Overexpression of eotaxin and the CCR3 receptor in human atherosclerosis: Using genomic technology to identify a potential novel pathway of vascular inflammation

Circulation

Volumn 102, Issue 18, 2000, Pages 2185-2189

  Haley, Kathleen J ^a   Lilly, Craig M ^a   Yang, Jeong Hee ^a   Feng, Yajun ^a   Kennedy, Scott P ^b   Turi, Thomas G ^b   Thompson, John F ^b   Sukhova, Galina H ^a   Libby, Peter ^a   Lee, Richard T ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Atherosclerosis; Genes; Inflammation

Indexed keywords

CD68 ANTIGEN; CHEMOKINE RECEPTOR CCR3; DNA; EOTAXIN; MESSENGER RNA;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0034739456     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.102.18.2185     Document Type: Article

References (27)

1. Association between myocardial infarction and the mast cells in the adventitia of the infarct-related coronary artery
2. Macrophage infiltration in acute coronary syndromes: Implications for plaque rupture
3. Molecular bases of the acute coronary syndromes
4. The unstable atheroma
5. Human vascular smooth muscle cell-monocyte interactions and metalloproteinase secretion in culture
6. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques: Potential role of matrix-degrading metalloproteinases and implications for plaque rupture
7. Tumor necrosis factor gene expression in human vascular intimal smooth muscle cells detected by in situ hybridization
8. Cytokines regulate vascular functions related to stability of the atherosclerotic plaque
9. The transcriptional program in the response of human fibroblasts to serum
10. Expression monitoring by hybridization to high-density oligonucleotide arrays
11. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
12. Atherosclerosis: An inflammatory disease
13. Absence of monocyte chemoattractant protein-reduces atherosclerosis in low density lipoprotein receptor-deficient mice
14. MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
15. Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis
16. Cytokines, chemokines, RANTES, and cotaxin
17. The MCP/eotaxin subfamily of CC chemokines
18. Expression and participation of eotaxin during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granuloma formation
19. The chemotactic cytokine eotaxin acts as a granulocyte-macrophage colony-stimulating factor during lung inflammation
20. Eotaxin and capping protein in experimental vasculopathy
21. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
22. High expression of the chemokine receptor CCR3 in human blood basophils: Role in activation by eotaxin, MCP4, and other chemokines
23. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: Association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES)
24. Antigen-induced eosinophilic lung inflammation develops in mice deficient in chemokine eotaxin
25. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia
26. Eotaxin and capping protein in experimental vasculopathy
27. Constitutive and cytokine-stimulated expression of eotaxin by human airway smooth muscle cells