Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: Transforming growth factor-β1-dependent and -independent effects

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 21, Issue 12, 2001, Pages 1928-1933

  Wang, Yenfeng ^a   Shiota, Naotaka ^a   Leskinen, Markus J ^a   Lindstedt, Ken A ^a   Kovanen, Petri T ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

Author keywords

Atherosclerosis; Chymase; Collagen; Smooth muscle cells; Transforming growth factor

Indexed keywords

CHYMASE; COLLAGEN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; AORTA; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL GROWTH; COLLAGEN SYNTHESIS; CORONARY ARTERY; CYTOKINE RELEASE; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MALE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEROSA; SMOOTH MUSCLE FIBER;

EID: 0035571572     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq1201.100227     Document Type: Article

References (33)

1. A pivotal role for TGF-beta in atherogenesis
2. Concordant upregulation of type II-TGF-beta-receptor, the cyclin-dependent kinases inhibitor P27 kip1 and cyclin E in human atherosclerotic tissue: Implications for lesion cellularity
3. Distinct patterns of transforming growth factor-beta isoform and receptor expression in human atherosclerotic lesions: Colocalization implicates TGF-beta in fibrofatty lesion development
4. Proliferation, migration, matrix turnover, and death of smooth muscle cells in native coronary and vein graft atherosclerosis
5. Latent transforming growth factor-β: Structural features and mechanisms of activation
6. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-betal-like molecule by plasmin during co-culture
7. Macrophage and foam cell release of matrix-bound growth factors: Role of plasminogen activation
8. Integrin-dependent induction of functional urokinase receptors in primary T lymphocytes
9. Role of mast cells in atherosclerosis
10. Human mast cell chymase and leukocyte elastase release latent transforming growth factor-β1 from the extracellular matrix of cultured human epithelial and endothelial cells
11. Activation of paracrine TGF-betal signaling upon stimulation and degranulation of rat serosal mast cells: A novel function for chymase
12. Heparin proteoglycans released from rat serosal mast cells inhibit proliferation of rat aortic smooth muscle cells in culture
13. Inhibition of macrophage-mediated low density lipoprotein oxidation by stimulated rat serosal mast cells
14. Chymase in exocytosed rat mast cell granules effectively proteolyzes apolipoprotein A1-containing lipoproteins, so reducing the cholesterol efflux-inducing ability of serum and aortic intimal fluid
15. Release of transforming growth factor-β1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin
16. Isolation of the pericellular matrix of human fibroblast cultures
17. Latent transforming growth factor-β1 associates to fibroblast extracellular matrix via latent TGF-β binding protein
18. Regulation of cell cycle and apoptosis by protein kinase C in rat myeloid leukemia cell line
19. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
20. Active transforming growth factor-β in wound repair: Determination using a new assay
21. Latent transforming growth factor-β-binding proteins (LTBPs): Structural extracellular matrix proteins for targeting TGF-β action
22. Proteolytic activation of latent transforming growth factor-β from fibroblast-conditioned medium
23. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
24. Physiological consequences of loss of plasminogen activator gene function in mice
25. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
26. Authentic matrix vesicles contain active metalloproteases (MMP): A role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta
27. The pathogenesis of atherosclerosis: A perspective for the 1990s
28. Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture
29. Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rapture in myocardial infarction
30. Mast cell granule remnants carry LDL into smooth muscle cells of synthetic phenotype and induce their conversion into foam cells
31. Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization
32. Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions
33. Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells