Deletion of the phosphoinositide 3-kinase p110γ gene attenuates murine atherosclerosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 19, 2007, Pages 8077-8082

  Chang, James D ^a,b,c   Sukhova, Galina K ^c   Libby, Peter ^c   Schvartz, Eugenia ^c   Lichtenstein, Alice H ^d   Field, Seth J ^e   Kennedy, Caitlin ^a   Madhavarapu, Swetha ^a   Luo, Ji ^b   Wu, Dianqing ^f   Cantley, Lewis C ^a,b,c  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d TUFTS UNIVERSITY   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Akt; G protein coupled receptors; Inflammation; Lipoproteins; Macrophage

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; CHEMOKINE; CHOLESTEROL; G PROTEIN COUPLED RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE DELETION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DRUG ANTAGONISM; GENETICS; OXIDATIVE STRESS; PHYSIOLOGY;

MURINAE; MUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; GENE DELETION; LIPOPROTEINS, LDL; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 34249951624     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0702663104     Document Type: Article

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