메뉴 건너뛰기




Volumn 16, Issue 3, 2009, Pages 350-361

Benefits of caloric restriction on brain aging and related pathological states: Understanding mechanisms to devise novel therapies

Author keywords

Aging; Caloric restriction; Caloric restriction mimetics; Neurodegeneration; Neuroprotection; Neurotrophic factors; Sirtuins; Transcription factors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DEOXYGLUCOSE; FENFLURAMINE; LEPTIN; N TERT BUTYL ALPHA PHENYLNITRONE; NEUROTROPHIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RESVERATROL; RIMONABANT; SIBUTRAMINE; SIRTUIN; TRANSCRIPTION FACTOR FOXO;

EID: 61949103873     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709787002637     Document Type: Review
Times cited : (32)

References (172)
  • 1
    • 35348972430 scopus 로고    scopus 로고
    • Genetic links between diet and lifespan: Shared mechanisms from yeast to humans
    • Bishop, N.A.; Guarente, L. Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nature Rev. Genet., 2007, 8, 835-44.
    • (2007) Nature Rev. Genet , vol.8 , pp. 835-844
    • Bishop, N.A.1    Guarente, L.2
  • 2
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of lifespan and upon the ultimate body size
    • McCay, C.M.; Crowell, M.F.; Maynard, L.A. The effect of retarded growth upon the length of lifespan and upon the ultimate body size. J. Nutr., 1935, 10, 63-79.
    • (1935) J. Nutr , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 3
    • 0017763799 scopus 로고
    • Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span
    • Klass, M.R. Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span. Mech. Aging Dev., 1977, 6, 413-29.
    • (1977) Mech. Aging Dev , vol.6 , pp. 413-429
    • Klass, M.R.1
  • 5
    • 34247158551 scopus 로고    scopus 로고
    • Calorie restriction in nonhuman primates: Assessing effects on brain and behavioral aging
    • Ingram, D.K.; Young, J.; Mattison, J.A. Calorie restriction in nonhuman primates: Assessing effects on brain and behavioral aging. Neuroscience, 2007, 145, 1359-64.
    • (2007) Neuroscience , vol.145 , pp. 1359-1364
    • Ingram, D.K.1    Young, J.2    Mattison, J.A.3
  • 7
    • 0030051986 scopus 로고    scopus 로고
    • Dietary lipids and antioxidants in Parkinson's disease: A population-based, case-control study
    • Logroscino, G.; Marder, K.; Cote, L.; Tang, M.X.; Shea, S.; Mayeux, R. Dietary lipids and antioxidants in Parkinson's disease: A population-based, case-control study. Ann. Neurol., 1996, 39, 89-94.
    • (1996) Ann. Neurol , vol.39 , pp. 89-94
    • Logroscino, G.1    Marder, K.2    Cote, L.3    Tang, M.X.4    Shea, S.5    Mayeux, R.6
  • 8
    • 0036334166 scopus 로고    scopus 로고
    • Caloric intake and the risk of Alzheimer disease
    • Luchsinger, J.A.; Tang, M.X.; Shea, S.; Mayeux, R. Caloric intake and the risk of Alzheimer disease. Arch. Neurol., 2002, 59, 1258-63.
    • (2002) Arch. Neurol , vol.59 , pp. 1258-1263
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 9
    • 0017841253 scopus 로고
    • Impact of Westernization on the nutrition of Japanese: Changes in physique, cancer, longevity and centenarians
    • Kagawa, Y. Impact of Westernization on the nutrition of Japanese: changes in physique, cancer, longevity and centenarians. Prev. Med., 1978, 7, 205-17.
    • (1978) Prev. Med , vol.7 , pp. 205-217
    • Kagawa, Y.1
  • 10
    • 0026478119 scopus 로고
    • Nutritional improvement, cardiovascular diseases and longevity in Japan
    • Mizushima, S.; Yapori, Y. Nutritional improvement, cardiovascular diseases and longevity in Japan. Nutr. Health, 1992, 8, 97-105.
    • (1992) Nutr. Health , vol.8 , pp. 97-105
    • Mizushima, S.1    Yapori, Y.2
  • 11
    • 77049302902 scopus 로고
    • La dieta de hombre a dias alternos in la alimentacion de los vejos
    • Vallejo, E.A. La dieta de hombre a dias alternos in la alimentacion de los vejos. Rev. Clin. Exp., 1957, 63, 25-6.
    • (1957) Rev. Clin. Exp , vol.63 , pp. 25-26
    • Vallejo, E.A.1
  • 12
    • 65549104349 scopus 로고    scopus 로고
    • Stunkard, A.J. Nutrition, aging and obesity. In Rockstein, M.; Sussman, M.L. Eds. Nutrition, longevity and aging. Rockstein, M.; Sussman, M.L. Eds.; Academic Press: New York; 1976, pp. 253-284.
    • Stunkard, A.J. Nutrition, aging and obesity. In Rockstein, M.; Sussman, M.L. Eds. Nutrition, longevity and aging. Rockstein, M.; Sussman, M.L. Eds.; Academic Press: New York; 1976, pp. 253-284.
  • 13
    • 0141720388 scopus 로고    scopus 로고
    • Calorie restriction and aging: Review of the literature and implications for studies in humans
    • Heilbronn, L.K.; Ravussin, E. Calorie restriction and aging: Review of the literature and implications for studies in humans. Am. J. Clin. Nutr., 2003, 78, 361-9.
    • (2003) Am. J. Clin. Nutr , vol.78 , pp. 361-369
    • Heilbronn, L.K.1    Ravussin, E.2
  • 14
    • 33645526333 scopus 로고    scopus 로고
    • Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: A randomized controlled trial
    • Heilbronn, L.K.; de Jonge, L.; Frisard, M.I.; DeLany, J.P.; Larson-Meyer, D.E. et al. Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: A randomized controlled trial. JAMA, 2006, 295, 1539-48.
    • (2006) JAMA , vol.295 , pp. 1539-1548
    • Heilbronn, L.K.1    de Jonge, L.2    Frisard, M.I.3    DeLany, J.P.4    Larson-Meyer, D.E.5
  • 15
    • 33748540014 scopus 로고    scopus 로고
    • Caloric restriction and intermittent fasting: Two potential diets for successful brain aging
    • Martin, B.; Mattson, M.P.; Maudsley, S. Caloric restriction and intermittent fasting: Two potential diets for successful brain aging. Ageing Res. Rev., 2006, 5, 332-53.
    • (2006) Ageing Res. Rev , vol.5 , pp. 332-353
    • Martin, B.1    Mattson, M.P.2    Maudsley, S.3
  • 16
    • 1342279434 scopus 로고    scopus 로고
    • Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity
    • Contestabile, A.; Ciani, E.; Contestabile, A. Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity. Brain Res., 2004, 1002, 162-6.
    • (2004) Brain Res , vol.1002 , pp. 162-166
    • Contestabile, A.1    Ciani, E.2    Contestabile, A.3
  • 17
    • 0031549576 scopus 로고    scopus 로고
    • Seminars in medicine of the beth israel deaconess medical center. Caloric intake and aging
    • Weindruch, R.; Sohal, R.S.; Seminars in medicine of the beth israel deaconess medical center. Caloric intake and aging. New Engl. J. Med., 1997, 337, 986-94.
    • (1997) New Engl. J. Med , vol.337 , pp. 986-994
    • Weindruch, R.1    Sohal, R.S.2
  • 18
    • 0038623652 scopus 로고    scopus 로고
    • Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
    • Anson, R.M.; Guo, Z.; de Cabo, R.; Iyun, T.; Rios, M.; Hagepanos, A.; Ingram, D.K.; Lane, M.A.; Mattson, M.P. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc. Natl. Acad. Sci. USA, 2003, 100, 6216-20.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6216-6220
    • Anson, R.M.1    Guo, Z.2    de Cabo, R.3    Iyun, T.4    Rios, M.5    Hagepanos, A.6    Ingram, D.K.7    Lane, M.A.8    Mattson, M.P.9
  • 19
    • 0037983775 scopus 로고    scopus 로고
    • Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes
    • Wu, X.; Motoshima, S.; Mahadev, K.; Stalker, T.J.; Scalia, R.; Goldstein, B.J. Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes, 2003, 52, 1355-63.
    • (2003) Diabetes , vol.52 , pp. 1355-1363
    • Wu, X.1    Motoshima, S.2    Mahadev, K.3    Stalker, T.J.4    Scalia, R.5    Goldstein, B.J.6
  • 20
    • 22744450382 scopus 로고    scopus 로고
    • Toward a unified theory of caloric restriction and longevity regulation
    • Sinclair, D.A. Toward a unified theory of caloric restriction and longevity regulation. Mech. Aging Devel., 2005, 126, 987-1002.
    • (2005) Mech. Aging Devel , vol.126 , pp. 987-1002
    • Sinclair, D.A.1
  • 21
    • 0141719852 scopus 로고    scopus 로고
    • Gene-diet interactions in brain aging and neurodegenerative disorders
    • Mattson, M.P. Gene-diet interactions in brain aging and neurodegenerative disorders. Ann. Intern. Med., 2003, 139, 441-4.
    • (2003) Ann. Intern. Med , vol.139 , pp. 441-444
    • Mattson, M.P.1
  • 22
    • 20444421530 scopus 로고
    • The need for controlled studies of the effects of meal frequency on health
    • Mattson, M.P. The need for controlled studies of the effects of meal frequency on health. Lancet, 2005, 365, 1978-80
    • (1978) Lancet , vol.2005 , pp. 365
    • Mattson, M.P.1
  • 24
    • 0032504657 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and ageing
    • Lenaz, G. Role of mitochondria in oxidative stress and ageing. Biochim. Biophys. Acta, 1998, 1366, 53-67.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 53-67
    • Lenaz, G.1
  • 26
    • 77049308856 scopus 로고
    • Aging: A theory based on free radicals and radiation chemistry
    • Harman, D. Aging: A theory based on free radicals and radiation chemistry. J. Gerontol., 1956, 11, 298-300.
    • (1956) J. Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 27
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman, D. The biologic clock: The mitochondria? J. Am. Geriatr. Soc., 1972, 20, 145-7.
    • (1972) J. Am. Geriatr. Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 28
    • 0032442835 scopus 로고    scopus 로고
    • Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice
    • Lee, C.M.; Aspnes, L.E.; Chung, S.S.; Weindruch, R.; Aiken, J.M. Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice. Ann. N. Y. Acad. Sci., 1998, 854, 182-91.
    • (1998) Ann. N. Y. Acad. Sci , vol.854 , pp. 182-191
    • Lee, C.M.1    Aspnes, L.E.2    Chung, S.S.3    Weindruch, R.4    Aiken, J.M.5
  • 31
    • 0033520166 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex
    • Polidori, M.C.; Mecocci, P.; Browne, P.; Senin, U.; Beal, M.F. Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex. Neurosci. Lett., 1999, 272, 53-6.
    • (1999) Neurosci. Lett , vol.272 , pp. 53-56
    • Polidori, M.C.1    Mecocci, P.2    Browne, P.3    Senin, U.4    Beal, M.F.5
  • 32
    • 18844462415 scopus 로고    scopus 로고
    • Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease
    • Wang, J.; Xiong, S.; Xie, C.; Markesbery, W.R.; Lovell, M.A. Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease. J. Neurochem., 2005, 93, 953-62.
    • (2005) J. Neurochem , vol.93 , pp. 953-962
    • Wang, J.1    Xiong, S.2    Xie, C.3    Markesbery, W.R.4    Lovell, M.A.5
  • 33
    • 0023904675 scopus 로고
    • Effect of 12 weeks' light-moderate underfeeding on 24-hour energy expenditure in normal male and female subjects
    • Garby, L.; Kurzer, M.S.; Lammert, O.; Nielsen, E. Effect of 12 weeks' light-moderate underfeeding on 24-hour energy expenditure in normal male and female subjects. Eur. J. Clin. Nutr., 1988, 42, 295-300.
    • (1988) Eur. J. Clin. Nutr , vol.42 , pp. 295-300
    • Garby, L.1    Kurzer, M.S.2    Lammert, O.3    Nielsen, E.4
  • 34
    • 0026640250 scopus 로고
    • Energy metabolism and aging: A lifelong study of Fischer 344 rats
    • McCarter, R.J.; Palmer, J. Energy metabolism and aging: A lifelong study of Fischer 344 rats. Am. J. Physiol., 1992, 263, E448-52.
    • (1992) Am. J. Physiol , vol.263
    • McCarter, R.J.1    Palmer, J.2
  • 36
    • 0035074805 scopus 로고    scopus 로고
    • Energy expenditure of rats subjected to long-term food restriction
    • Santos-Pinto, F.N.; Luz, J.; Griggio, M.A. Energy expenditure of rats subjected to long-term food restriction. Int. J. Food Sci. Nutr., 2001, 52, 193-200.
    • (2001) Int. J. Food Sci. Nutr , vol.52 , pp. 193-200
    • Santos-Pinto, F.N.1    Luz, J.2    Griggio, M.A.3
  • 38
    • 1842544684 scopus 로고    scopus 로고
    • Effects of short- and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production
    • Bevilacqua, L.; Ramsey, J.J.; Hagopian, K.; Weindruch, R.; Harper, M.E. Effects of short- and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production. Am. J. Physiol. Endocrinol. Metab., 2004, 286, E852-61.
    • (2004) Am. J. Physiol. Endocrinol. Metab , vol.286
    • Bevilacqua, L.1    Ramsey, J.J.2    Hagopian, K.3    Weindruch, R.4    Harper, M.E.5
  • 41
    • 0034669375 scopus 로고    scopus 로고
    • Restriction of energy intake, energy expenditure, and aging
    • Ramsey, J.J.; Harper, M.E.; Weindruch, R. Restriction of energy intake, energy expenditure, and aging. Free Rad. Biol. Med., 2000, 29, 946-68.
    • (2000) Free Rad. Biol. Med , vol.29 , pp. 946-968
    • Ramsey, J.J.1    Harper, M.E.2    Weindruch, R.3
  • 43
    • 1442314701 scopus 로고    scopus 로고
    • Adipose tissue energy metabolism: Altered gene expression profile of mice subjected to long-term caloric restriction
    • Higami, Y.; Pugh, T.D.; Page, G.P.; Allison,D. B.; Prolla, T.A.; Weindruch, R. Adipose tissue energy metabolism: Altered gene expression profile of mice subjected to long-term caloric restriction. FASEB J., 2004, 18, 415-7.
    • (2004) FASEB J , vol.18 , pp. 415-417
    • Higami, Y.1    Pugh, T.D.2    Page, G.P.3    Allison, D.B.4    Prolla, T.A.5    Weindruch, R.6
  • 45
    • 0035403165 scopus 로고    scopus 로고
    • Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart
    • Gredilla, R.; Sanz, A.; Lopez-Torres, M.; Barja, G. Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart. FASEB J., 2001, 15, 1589-91.
    • (2001) FASEB J , vol.15 , pp. 1589-1591
    • Gredilla, R.1    Sanz, A.2    Lopez-Torres, M.3    Barja, G.4
  • 46
    • 0036569788 scopus 로고    scopus 로고
    • Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria
    • Lopez-Torres, M.; Gredilla, R.; Sanz, A.; Barja, G. Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria. Free Rad. Biol. Med., 2002, 32, 882-9.
    • (2002) Free Rad. Biol. Med , vol.32 , pp. 882-889
    • Lopez-Torres, M.1    Gredilla, R.2    Sanz, A.3    Barja, G.4
  • 47
    • 0036756755 scopus 로고    scopus 로고
    • Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls
    • Pamplona, R.; Portero-Otin, M.; Requena, J.; Gredilla, R.; Barja, G. Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls. Mech. Aging Dev., 2002, 123, 1437-46.
    • (2002) Mech. Aging Dev , vol.123 , pp. 1437-1446
    • Pamplona, R.1    Portero-Otin, M.2    Requena, J.3    Gredilla, R.4    Barja, G.5
  • 50
    • 0037069375 scopus 로고    scopus 로고
    • Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts
    • Lee, C.K.; Allison, D.B.; Brand, J.; Weindruch, R.; Prolla, T.A. Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc. Natl. Acad. Sci. USA, 2002, 99, 14988-93.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14988-14993
    • Lee, C.K.1    Allison, D.B.2    Brand, J.3    Weindruch, R.4    Prolla, T.A.5
  • 54
    • 0033610079 scopus 로고    scopus 로고
    • Gene expression profile of aging and its retardation by caloric restriction
    • Lee, C.K.; Klopp. R.G.; Weindruch, R.; Prolla, T.A. Gene expression profile of aging and its retardation by caloric restriction. Science, 1999, 285, 1390-3.
    • (1999) Science , vol.285 , pp. 1390-1393
    • Lee, C.K.1    Klopp, R.G.2    Weindruch, R.3    Prolla, T.A.4
  • 57
    • 0024829444 scopus 로고
    • The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris
    • Stewart, J.; Mitchell, J.; Kalant, N. The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris. Neurobiol. Aging, 1989, 10, 669-75.
    • (1989) Neurobiol. Aging , vol.10 , pp. 669-675
    • Stewart, J.1    Mitchell, J.2    Kalant, N.3
  • 58
    • 0025117957 scopus 로고
    • Effect of life-long hypocaloric diet on age-related changes in motor and cognitive behavior in a rat population
    • Pitsikas, N.; Carli, M.; Fidecka, S.; Algeri, S. Effect of life-long hypocaloric diet on age-related changes in motor and cognitive behavior in a rat population. Neurobiol. Aging, 1990, 11, 417-23.
    • (1990) Neurobiol. Aging , vol.11 , pp. 417-423
    • Pitsikas, N.1    Carli, M.2    Fidecka, S.3    Algeri, S.4
  • 59
    • 0032168690 scopus 로고    scopus 로고
    • Aging of glutamate receptors: Correlations between binding and spatial memory performance in mice
    • Magnusson, K.R. Aging of glutamate receptors: Correlations between binding and spatial memory performance in mice. Mech. Ageing Dev., 1998, 104, 227-48.
    • (1998) Mech. Ageing Dev , vol.104 , pp. 227-248
    • Magnusson, K.R.1
  • 60
    • 0027255341 scopus 로고
    • Mid-life onset of dietary restriction extends life and prolongs cognitive functioning
    • Means, L.W.; Higgins, J.L.; Fernandez, T.J. Mid-life onset of dietary restriction extends life and prolongs cognitive functioning. Physiol. Behav., 1993, 54, 503-8.
    • (1993) Physiol. Behav , vol.54 , pp. 503-508
    • Means, L.W.1    Higgins, J.L.2    Fernandez, T.J.3
  • 61
    • 0030249761 scopus 로고    scopus 로고
    • Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse
    • Dubey, A.; Forster, M.J.; Lal, H.; Sohal, R.S. Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse. Arch. Biochem. Biophys., 1996, 333, 189-97.
    • (1996) Arch. Biochem. Biophys , vol.333 , pp. 189-197
    • Dubey, A.1    Forster, M.J.2    Lal, H.3    Sohal, R.S.4
  • 62
    • 0029054997 scopus 로고
    • Effects of dietary restriction on motor learning and cerebellar noradrenergic dysfunction in aged F344 rats
    • Gould, T.J.; Bowenkamp, K.E.; Larson, G.; Zahniser, N.R.; Bickford, P.C. Effects of dietary restriction on motor learning and cerebellar noradrenergic dysfunction in aged F344 rats. P.C. Brain Res., 1995, 684, 150-8.
    • (1995) P.C. Brain Res , vol.684 , pp. 150-158
    • Gould, T.J.1    Bowenkamp, K.E.2    Larson, G.3    Zahniser, N.R.4    Bickford, P.C.5
  • 63
    • 0034738147 scopus 로고    scopus 로고
    • Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression
    • Eckles-Smith, K.; Clayton, D.; Bickford, P.; Browning, M.D. Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression. Mol. Brain Res., 2000, 78, 154-62.
    • (2000) Mol. Brain Res , vol.78 , pp. 154-162
    • Eckles-Smith, K.1    Clayton, D.2    Bickford, P.3    Browning, M.D.4
  • 64
    • 0035833068 scopus 로고    scopus 로고
    • Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
    • Cameron, H.A.; McKay, R.D. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J. Comp. Neurol., 2001, 435, 406-17.
    • (2001) J. Comp. Neurol , vol.435 , pp. 406-417
    • Cameron, H.A.1    McKay, R.D.2
  • 65
    • 34249094507 scopus 로고    scopus 로고
    • How widespread is adult neurogenesis in mammals?
    • Gould, E. How widespread is adult neurogenesis in mammals? Nat. Rev. Neurosci., 2007, 8, 481-8.
    • (2007) Nat. Rev. Neurosci , vol.8 , pp. 481-488
    • Gould, E.1
  • 66
    • 0034489693 scopus 로고    scopus 로고
    • Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats
    • Lee, J.; Duan, W.; Long, J.M.; Ingram, D.K.; Mattson, M.P. Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats. J. Mol. Neurosci., 2000, 15, 99-108.
    • (2000) J. Mol. Neurosci , vol.15 , pp. 99-108
    • Lee, J.1    Duan, W.2    Long, J.M.3    Ingram, D.K.4    Mattson, M.P.5
  • 67
    • 1242271233 scopus 로고    scopus 로고
    • Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice
    • Bondolfi, L.; Ermini, F.; Long, J.M.; Ingram, D.K.; Jucker, M. Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice. Neurobiol. Aging, 2004, 25, 33-403
    • (2004) Neurobiol. Aging , vol.25 , pp. 33-403
    • Bondolfi, L.1    Ermini, F.2    Long, J.M.3    Ingram, D.K.4    Jucker, M.5
  • 68
    • 0036488190 scopus 로고    scopus 로고
    • Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice
    • Lee, J.; Seroogy, K.B.; Mattson, M.P. Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice. J. Neurochem., 2002, 80, 539-47.
    • (2002) J. Neurochem , vol.80 , pp. 539-547
    • Lee, J.1    Seroogy, K.B.2    Mattson, M.P.3
  • 69
    • 0036734833 scopus 로고    scopus 로고
    • Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
    • Lee, J.; Duan, W.; Mattson, M.P. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J. Neurochem., 2002, 82, 1367-75.
    • (2002) J. Neurochem , vol.82 , pp. 1367-1375
    • Lee, J.1    Duan, W.2    Mattson, M.P.3
  • 71
    • 0037362863 scopus 로고    scopus 로고
    • Lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain
    • Shelke, R.R.; Leeuwenburgh, C. Lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain. FASEB J., 2003, 17, 494-6.
    • (2003) FASEB J , vol.17 , pp. 494-496
    • Shelke, R.R.1    Leeuwenburgh, C.2
  • 72
    • 3242659914 scopus 로고    scopus 로고
    • Effects of age and caloric restriction on brain neuronal cell death/survival
    • Hiona, A.; Leeuwenburgh, C. Effects of age and caloric restriction on brain neuronal cell death/survival. Ann. N.Y. Acad. Sci., 2004, 1019, 96-105.
    • (2004) Ann. N.Y. Acad. Sci , vol.1019 , pp. 96-105
    • Hiona, A.1    Leeuwenburgh, C.2
  • 73
    • 0030717684 scopus 로고    scopus 로고
    • Life-long dietary restriction attenuates age-related increases in hippocampal glial fibrillary acidic protein mRNA
    • Major, D.E.; Kessiak, J.P.; Cotman, C.W.; Finch, C.E.; Day, J.R. Life-long dietary restriction attenuates age-related increases in hippocampal glial fibrillary acidic protein mRNA. Neurobiol. Aging, 1997, 18, 523-6.
    • (1997) Neurobiol. Aging , vol.18 , pp. 523-526
    • Major, D.E.1    Kessiak, J.P.2    Cotman, C.W.3    Finch, C.E.4    Day, J.R.5
  • 74
    • 34250622873 scopus 로고    scopus 로고
    • Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis
    • Shi, L.; Adams, M.M.; Linville, M.C.; Newton, I.G.; Forbes, M.E.; Long, A.B.; Riddle, D.R.; Brunso-Bechtold, J.K. Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis. Exp. Neurol., 2007, 206, 70-9.
    • (2007) Exp. Neurol , vol.206 , pp. 70-79
    • Shi, L.1    Adams, M.M.2    Linville, M.C.3    Newton, I.G.4    Forbes, M.E.5    Long, A.B.6    Riddle, D.R.7    Brunso-Bechtold, J.K.8
  • 76
    • 0342275259 scopus 로고    scopus 로고
    • Caloric restriction enhances evoked DA overflow in striatum and nucleus accumbens of aged Fischer 344 rats
    • Diao, L.H.; Bickford, P.C.; Stevens, J.O.; Cline, E.J.; Gerhardt, G.A. Caloric restriction enhances evoked DA overflow in striatum and nucleus accumbens of aged Fischer 344 rats. Brain Res., 1997, 763, 276-80.
    • (1997) Brain Res , vol.763 , pp. 276-280
    • Diao, L.H.1    Bickford, P.C.2    Stevens, J.O.3    Cline, E.J.4    Gerhardt, G.A.5
  • 77
    • 0035097725 scopus 로고    scopus 로고
    • Calorie restriction in obesity: Prevention of kidney disease in rodents
    • Stern, J.S.; Gades, M.D.; Wheeldon, C.M.; Borchers, A.T. Calorie restriction in obesity: Prevention of kidney disease in rodents. J. Nutr., 2001, 131, 913-7S.
    • (2001) J. Nutr , vol.131
    • Stern, J.S.1    Gades, M.D.2    Wheeldon, C.M.3    Borchers, A.T.4
  • 78
    • 0013072999 scopus 로고    scopus 로고
    • Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans
    • Hursting, S.D.; Lavigne, J.A.; Berrigan, D.; Perkins, S.N.; Barret, J.C. Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans. Annu. Rev. Med., 2003, 54, 13-521.
    • (2003) Annu. Rev. Med , vol.54 , pp. 13-521
    • Hursting, S.D.1    Lavigne, J.A.2    Berrigan, D.3    Perkins, S.N.4    Barret, J.C.5
  • 80
    • 14644390872 scopus 로고    scopus 로고
    • Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems
    • Mattson, M.P.; Wan, R. Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems. J. Nutr. Biochem., 2005, 16, 129-37.
    • (2005) J. Nutr. Biochem , vol.16 , pp. 129-137
    • Mattson, M.P.1    Wan, R.2
  • 81
    • 0035030699 scopus 로고    scopus 로고
    • Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury
    • Duan, W.; Lee, J.; Guo, Z.; Mattson, M.P. Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury. J. Mol. Neurosci., 2001, 16, 1-12.
    • (2001) J. Mol. Neurosci , vol.16 , pp. 1-12
    • Duan, W.1    Lee, J.2    Guo, Z.3    Mattson, M.P.4
  • 82
    • 0035145760 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice
    • Duan, W.; Guo, Z.; Mattson, M.P. Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. J. Neurochem., 2001, 76, 619-26.
    • (2001) J. Neurochem , vol.76 , pp. 619-626
    • Duan, W.1    Guo, Z.2    Mattson, M.P.3
  • 83
    • 1342279434 scopus 로고    scopus 로고
    • Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity
    • Contestabile, A., Ciani, E.; Contestabile, A. Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity. Brain Res., 2004, 1002, 162-6.
    • (2004) Brain Res , vol.1002 , pp. 162-166
    • Contestabile, A.1    Ciani, E.2    Contestabile, A.3
  • 84
    • 26244443441 scopus 로고    scopus 로고
    • Neuroprotective potential of dietary restriction against kainate-induced excitotoxicity in adult male Wistar rats
    • Sharma, S.; Kaur, G. Neuroprotective potential of dietary restriction against kainate-induced excitotoxicity in adult male Wistar rats. Brain Res. Bull., 2005, 67, 482-91.
    • (2005) Brain Res. Bull , vol.67 , pp. 482-491
    • Sharma, S.1    Kaur, G.2
  • 85
    • 0032925851 scopus 로고    scopus 로고
    • Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
    • Bruce-Keller, A.J.; Umberger, G.; McFall, R.; Mattson, M.P. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann. Neurol., 1999, 45, 8-15.
    • (1999) Ann. Neurol , vol.45 , pp. 8-15
    • Bruce-Keller, A.J.1    Umberger, G.2    McFall, R.3    Mattson, M.P.4
  • 86
    • 0346098178 scopus 로고    scopus 로고
    • Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice
    • Lee, J.; Auyeung, W.W.; Mattson, M.P. Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice. Neuromol. Med., 2003, 4, 179-96.
    • (2003) Neuromol. Med , vol.4 , pp. 179-196
    • Lee, J.1    Auyeung, W.W.2    Mattson, M.P.3
  • 87
    • 44549089070 scopus 로고    scopus 로고
    • Dietary restriction enhances kainate-induced increase in NCAM while blocking the glial activation in adult rat brain
    • Sharma, S.; Kaur, G. Dietary restriction enhances kainate-induced increase in NCAM while blocking the glial activation in adult rat brain. Neurochem. Res., 2007, 33, 1178-88.
    • (2007) Neurochem. Res , vol.33 , pp. 1178-1188
    • Sharma, S.1    Kaur, G.2
  • 88
    • 0001611514 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism
    • Yu, Z.F.; Mattson, M.P. Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism. J. Neurosci. Res., 1999, 15, 830-9.
    • (1999) J. Neurosci. Res , vol.15 , pp. 830-839
    • Yu, Z.F.1    Mattson, M.P.2
  • 89
    • 36849077218 scopus 로고    scopus 로고
    • Food restriction attenuates ischemia-induced spatial learning and memory deficits despite extensive CA1 ischemic injury
    • Roberge, M.C.; Hotte-Bernard, J.; Messier, C.; Plamondon, H. Food restriction attenuates ischemia-induced spatial learning and memory deficits despite extensive CA1 ischemic injury. Behav. Brain Res., 2008, 187, 123-32.
    • (2008) Behav. Brain Res , vol.187 , pp. 123-132
    • Roberge, M.C.1    Hotte-Bernard, J.2    Messier, C.3    Plamondon, H.4
  • 90
    • 0034575582 scopus 로고    scopus 로고
    • Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism
    • Calingasan, N.Y.; Gibson, G.E. Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism. Brain Res., 2000, 885, 62-9.
    • (2000) Brain Res , vol.885 , pp. 62-69
    • Calingasan, N.Y.1    Gibson, G.E.2
  • 91
    • 0033566286 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
    • Duan, W.; Mattson, M.P. Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J. Neurosci. Res., 1999, 57, 195-206.
    • (1999) J. Neurosci. Res , vol.57 , pp. 195-206
    • Duan, W.1    Mattson, M.P.2
  • 95
    • 33947264635 scopus 로고    scopus 로고
    • Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
    • Halagappa, M., Guo, Z.; Pearson, M.; Matsuoka, Y.; Cutler, R.G.; LaFerla, F.M.; Mattson, M.P. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol. Dis., 2007, 26, 212-20.
    • (2007) Neurobiol. Dis , vol.26 , pp. 212-220
    • Halagappa, M.1    Guo, Z.2    Pearson, M.3    Matsuoka, Y.4    Cutler, R.G.5    LaFerla, F.M.6    Mattson, M.P.7
  • 97
    • 0037418339 scopus 로고    scopus 로고
    • Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
    • Duan, W.; Guo, Z.; Jiang, H.; Ware, M.; Li, X.J.; Mattson, M.P. Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proc. Natl. Acad. Sci. USA, 2003, 100, 2911-6.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2911-2916
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Li, X.J.5    Mattson, M.P.6
  • 98
    • 0033606410 scopus 로고    scopus 로고
    • No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/ Zn-superoxide dismutase mutant mice
    • Pedersen, W.A.; Mattson, M.P. No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/ Zn-superoxide dismutase mutant mice. Brain Res., 1999, 833, 117-20.
    • (1999) Brain Res , vol.833 , pp. 117-120
    • Pedersen, W.A.1    Mattson, M.P.2
  • 99
    • 3343020674 scopus 로고    scopus 로고
    • Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: Benefit of a high-energy diet in a transgenic mouse model
    • Dupuis, L.; Oudart, H.; René, F.; Gonzalez de Aguilar, J.L.; Loeffler, J.P. Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: Benefit of a high-energy diet in a transgenic mouse model. Proc. Natl. Acad. Sci. USA, 2004, 101, 11159-64.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11159-11164
    • Dupuis, L.1    Oudart, H.2    René, F.3    Gonzalez de Aguilar, J.L.4    Loeffler, J.P.5
  • 100
    • 33751091740 scopus 로고    scopus 로고
    • Energy intake and amyotrophic lateral sclerosis
    • Mattson, M.P.; Cutler, R.G.; Camandola, S. Energy intake and amyotrophic lateral sclerosis. Neuromol. Med., 2007, 9, 17-20
    • (2007) Neuromol. Med , vol.9 , pp. 17-20
    • Mattson, M.P.1    Cutler, R.G.2    Camandola, S.3
  • 101
    • 18044366164 scopus 로고    scopus 로고
    • The metabolic hypothesis in amyotrophic lateral sclerosis: Insights from mutant Cu/Zn-superoxide dismutase mice
    • Gonzalez de Aguilar, J.L.; Dupuis, L.; Oudart, H.; Loeffler, J.P. The metabolic hypothesis in amyotrophic lateral sclerosis: Insights from mutant Cu/Zn-superoxide dismutase mice. Biomed. Pharmacother., 2005, 59, 190-6.
    • (2005) Biomed. Pharmacother , vol.59 , pp. 190-196
    • Gonzalez de Aguilar, J.L.1    Dupuis, L.2    Oudart, H.3    Loeffler, J.P.4
  • 102
    • 0001883841 scopus 로고    scopus 로고
    • Molecular mechanisms of brain aging and neurodegenerative disorders: Lessons from dietary restriction
    • Prolla, T.A.; Mattson, M.P. Molecular mechanisms of brain aging and neurodegenerative disorders: Lessons from dietary restriction. Trends Neurosci., 2001, 24, S21-31.
    • (2001) Trends Neurosci , vol.24
    • Prolla, T.A.1    Mattson, M.P.2
  • 103
    • 11144321344 scopus 로고    scopus 로고
    • Lessons learned from gene expression profile studies of aging and caloric restriction
    • Park, S.K.; Prolla, T.A. Lessons learned from gene expression profile studies of aging and caloric restriction. Ageing Res. Rev., 2005, 4, 55-65.
    • (2005) Ageing Res. Rev , vol.4 , pp. 55-65
    • Park, S.K.1    Prolla, T.A.2
  • 104
    • 0033610079 scopus 로고    scopus 로고
    • Gene expression profile of aging and its retardation by caloric restriction
    • Lee, C.K.; Klopp, R.G.; Weindruch, R.; Prolla, T.A. Gene expression profile of aging and its retardation by caloric restriction Science, 1999, 285, 1390-3.
    • (1999) Science , vol.285 , pp. 1390-1393
    • Lee, C.K.1    Klopp, R.G.2    Weindruch, R.3    Prolla, T.A.4
  • 105
    • 0000847978 scopus 로고    scopus 로고
    • Gene-expression profile of the ageing brain in mice
    • Lee, C.K.; Weindruch, R.; Prolla, T.A. Gene-expression profile of the ageing brain in mice. Nat. Genet., 2000, 25, 294-7.
    • (2000) Nat. Genet , vol.25 , pp. 294-297
    • Lee, C.K.1    Weindruch, R.2    Prolla, T.A.3
  • 107
    • 37749037128 scopus 로고    scopus 로고
    • Dietary factors, hormesis and health
    • Mattson, M.P. Dietary factors, hormesis and health. Ageing Res. Rev., 2008, 7, 43-8.
    • (2008) Ageing Res. Rev , vol.7 , pp. 43-48
    • Mattson, M.P.1
  • 109
    • 0034924812 scopus 로고    scopus 로고
    • Folding of newly translated proteins in vivo: The role of molecular chaperones
    • Frydman, J. Folding of newly translated proteins in vivo: The role of molecular chaperones. Annu. Rev. Biochem., 2001, 70, 603-47.
    • (2001) Annu. Rev. Biochem , vol.70 , pp. 603-647
    • Frydman, J.1
  • 111
    • 0032727617 scopus 로고    scopus 로고
    • Warrick, J.M., Chan, H.Y.; Gray-Board, G.L.; Chai, Y.; Paulson, H.L.; Bonini, N.M. Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat. Genet., 1999, 23, 425-8.
    • Warrick, J.M., Chan, H.Y.; Gray-Board, G.L.; Chai, Y.; Paulson, H.L.; Bonini, N.M. Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat. Genet., 1999, 23, 425-8.
  • 112
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu, Z.F.; Luo, W.; Fu, W.; Mattson, M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol., 1999, 155, 302-14.
    • (1999) Exp. Neurol , vol.155 , pp. 302-314
    • Yu, Z.F.1    Luo, W.2    Fu, W.3    Mattson, M.P.4
  • 113
    • 0026328490 scopus 로고
    • The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity
    • Lowenstein, D.H.; Chan, P.H.; Miles, M.F. The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity. Neuron, 1991, 7, 1053-60.
    • (1991) Neuron , vol.7 , pp. 1053-1060
    • Lowenstein, D.H.1    Chan, P.H.2    Miles, M.F.3
  • 115
    • 33744934491 scopus 로고    scopus 로고
    • Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity
    • Lee, J.; Kim, S.J.; Son, T.G.; Chan, S.L.; Mattson, M.P. Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity. J. Neurosci. Res., 2006, 83, 1552-7.
    • (2006) J. Neurosci. Res , vol.83 , pp. 1552-1557
    • Lee, J.1    Kim, S.J.2    Son, T.G.3    Chan, S.L.4    Mattson, M.P.5
  • 116
    • 0035970719 scopus 로고    scopus 로고
    • Interferon-gamma-induced changes in synaptic activity and AMPA receptor clustering in hippocampal cultures
    • Vikman, K.S.; Owe-Larsson, B.; Brask, J.; Kristensson, K.S.; Hill, R.H. Interferon-gamma-induced changes in synaptic activity and AMPA receptor clustering in hippocampal cultures. Brain Res., 2001, 896, 18-29.
    • (2001) Brain Res , vol.896 , pp. 18-29
    • Vikman, K.S.1    Owe-Larsson, B.2    Brask, J.3    Kristensson, K.S.4    Hill, R.H.5
  • 117
    • 1842663407 scopus 로고    scopus 로고
    • Interferon-gamma but not TNF alpha promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells
    • Wong, G.; Goldshmit, Y.; Turnley, A.M. Interferon-gamma but not TNF alpha promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells. Exp. Neurol., 2004, 187, 171-7.
    • (2004) Exp. Neurol , vol.187 , pp. 171-177
    • Wong, G.1    Goldshmit, Y.2    Turnley, A.M.3
  • 118
    • 3042748278 scopus 로고    scopus 로고
    • Exposure to interferon-gamma during synaptogenesis increases inhibitory activity after a latent period in cultured rat hippocampal neurons
    • Brask, J.; Kristensson, K.; Hill, R.K. Exposure to interferon-gamma during synaptogenesis increases inhibitory activity after a latent period in cultured rat hippocampal neurons. Eur. J. Neurosci., 2004, 19, 3193-201.
    • (2004) Eur. J. Neurosci , vol.19 , pp. 3193-3201
    • Brask, J.1    Kristensson, K.2    Hill, R.K.3
  • 120
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon, C.; Chang, J.; Gensh, A.; Rudner, A.; Tabtiang, R. A C. elegans mutant that lives twice as long as wild type. Nature, 1993, 366, 461-4.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensh, A.3    Rudner, A.4    Tabtiang, R.5
  • 121
    • 0029108666 scopus 로고
    • Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points
    • Lane, M.A.; Ball, S.S.; Ingram, D.K.; Cutler, R.G.; Engel, J.; Read, V.; Roth, G.S. Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points. Am. J. Physiol., 1995, 268, E941-8.
    • (1995) Am. J. Physiol , vol.268
    • Lane, M.A.1    Ball, S.S.2    Ingram, D.K.3    Cutler, R.G.4    Engel, J.5    Read, V.6    Roth, G.S.7
  • 122
    • 0032836611 scopus 로고    scopus 로고
    • Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice
    • Gazdag, A.C.; Dumke, C.L.; Kahn, C.R.; Cartee, G.D. Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice. Diabetes, 1999, 48, 1930-6
    • (1999) Diabetes , vol.48 , pp. 1930-1936
    • Gazdag, A.C.1    Dumke, C.L.2    Kahn, C.R.3    Cartee, G.D.4
  • 123
    • 0034102203 scopus 로고    scopus 로고
    • The effect of age on cyclooxygenase-2 gene expression: NF-kappaB activation and IkappaBalpha degradation
    • Kim, H.J.; Kim, K.W.; Yu, B.P.; Chung, H.Y. The effect of age on cyclooxygenase-2 gene expression: NF-kappaB activation and IkappaBalpha degradation. Free Rad. Biol. Med., 2000, 28, 683-92.
    • (2000) Free Rad. Biol. Med , vol.28 , pp. 683-692
    • Kim, H.J.1    Kim, K.W.2    Yu, B.P.3    Chung, H.Y.4
  • 124
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • Nakae, J.; Kitamura, T.; Silver, D.L.; Accili, D. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J. Clin. Invest., 2001, 108, 1359-67.
    • (2001) J. Clin. Invest , vol.108 , pp. 1359-1367
    • Nakae, J.1    Kitamura, T.2    Silver, D.L.3    Accili, D.4
  • 125
    • 0035823515 scopus 로고    scopus 로고
    • Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences
    • Yeagley, D.; Guo, S.; Unterman, T.; Quinn, P.G. Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences. J. Biol. Chem., 2001, 276, 33705-10.
    • (2001) J. Biol. Chem , vol.276 , pp. 33705-33710
    • Yeagley, D.1    Guo, S.2    Unterman, T.3    Quinn, P.G.4
  • 127
    • 0038363836 scopus 로고    scopus 로고
    • Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16
    • Imae, M.; Fu, Z.; Yoshida, A.; Noguchi, T.; Kato, H. Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16. J. Mol. Endocrinol., 2003, 30, 253-62.
    • (2003) J. Mol. Endocrinol , vol.30 , pp. 253-262
    • Imae, M.1    Fu, Z.2    Yoshida, A.3    Noguchi, T.4    Kato, H.5
  • 128
    • 0142200472 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
    • Furuyama, T.; Kitayama, K.; Yamashita, H.; Mori, N. Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. Biochem. J., 2003, 375, 365-71.
    • (2003) Biochem. J , vol.375 , pp. 365-371
    • Furuyama, T.1    Kitayama, K.2    Yamashita, H.3    Mori, N.4
  • 129
    • 3142734385 scopus 로고    scopus 로고
    • Additive regulation of hepatic gene expression by dwarfism and caloric restriction
    • Tsuchiya, T.; Dhahbi, J.M.; Cui, X.; Mote, P.L.; Bartke, A.; Spindler, S.R. Additive regulation of hepatic gene expression by dwarfism and caloric restriction. Physiol. Genom., 2004, 17, 307-15.
    • (2004) Physiol. Genom , vol.17 , pp. 307-315
    • Tsuchiya, T.1    Dhahbi, J.M.2    Cui, X.3    Mote, P.L.4    Bartke, A.5    Spindler, S.R.6
  • 130
    • 12344335482 scopus 로고    scopus 로고
    • Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction
    • Al-Regaiey, K.A.; Masternak, M.M.; Bonkowski, M.; Sun, L.; Bartke, A. Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. Endocrinology, 2005, 146, 851-60.
    • (2005) Endocrinology , vol.146 , pp. 851-860
    • Al-Regaiey, K.A.1    Masternak, M.M.2    Bonkowski, M.3    Sun, L.4    Bartke, A.5
  • 131
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/ DAF-16
    • Oh, S.W.; Mukhopadhyay, A.; Svrzikapa, N.; Jiang, F.; Davis, R.J.; Tissenbaum, H.A. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/ DAF-16. Proc. Natl. Acad. Sci. USA, 2005, 102, 4494-9.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 4494-4499
    • Oh, S.W.1    Mukhopadhyay, A.2    Svrzikapa, N.3    Jiang, F.4    Davis, R.J.5    Tissenbaum, H.A.6
  • 132
    • 17044408768 scopus 로고    scopus 로고
    • JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
    • Wang, M.C.; Bohmann, D.; Jasper, H. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell, 2005, 121, 115-25.
    • (2005) Cell , vol.121 , pp. 115-125
    • Wang, M.C.1    Bohmann, D.2    Jasper, H.3
  • 134
    • 0035942222 scopus 로고    scopus 로고
    • Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys
    • Kayo, T.; Allison, D.B.; Weindruch, R.; Prolla, T.A. Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys. Proc. Natl. Acad. Sci. USA, 2001, 98, 5093-8.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5093-5098
    • Kayo, T.1    Allison, D.B.2    Weindruch, R.3    Prolla, T.A.4
  • 136
    • 10844236451 scopus 로고    scopus 로고
    • Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
    • Nemoto, S.; Fergusson, M.M.; Finkel, T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science, 2004, 306, 2105-8.
    • (2004) Science , vol.306 , pp. 2105-2108
    • Nemoto, S.1    Fergusson, M.M.2    Finkel, T.3
  • 137
    • 0018644035 scopus 로고
    • MAR1-a Regulator of the HMa and HMalpha Loci in Saccharomices cerevisiae
    • Klar, A.J.; Fogel, S.; Macleod, K. MAR1-a Regulator of the HMa and HMalpha Loci in Saccharomices cerevisiae. Genetics, 1979, 93, 37-50.
    • (1979) Genetics , vol.93 , pp. 37-50
    • Klar, A.J.1    Fogel, S.2    Macleod, K.3
  • 138
    • 0023340731 scopus 로고
    • Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
    • Rine, J.; Herskowitz, I. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics, 1987, 116, 9-22.
    • (1987) Genetics , vol.116 , pp. 9-22
    • Rine, J.1    Herskowitz, I.2
  • 139
    • 0028897013 scopus 로고
    • Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae
    • Kennedy, B.K.; Austriaco, N.R.Jr.; Zhang, J.; Guarente, L. Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell, 1995, 80, 485-96.
    • (1995) Cell , vol.80 , pp. 485-496
    • Kennedy, B.K.1    Austriaco Jr, N.R.2    Zhang, J.3    Guarente, L.4
  • 140
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein, M.; McVey, M.; Guarente, L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev., 1999, 13, 2570-80.
    • (1999) Genes Dev , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 141
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum, H.A.; Guarente, L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature, 2001, 410, 227-30.
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 142
    • 8644224064 scopus 로고    scopus 로고
    • Sir2 mediates longevity in the fly through a pathway related to calorie restriction
    • Rogina, B.; Helfand, S.L. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. USA, 2004, 101, 15998-6003.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 15998-16003
    • Rogina, B.1    Helfand, S.L.2
  • 143
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 in an NAD-dependent histone deacetylase
    • Imai, S.; Armstrong, C.M.; Kaeberlein, M.; Guarente, L. Transcriptional silencing and longevity protein Sir2 in an NAD-dependent histone deacetylase. Nature, 2000, 403, 795-800.
    • (2000) Nature , vol.403 , pp. 795-800
    • Imai, S.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 146
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung, F.; Hoberg, J.E.; Ramsey, C.S.; Keller, M.D.; Jones, D.R.; Frye, R.A.; Mayo, M.W. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J., 2004, 23, 2369-80.
    • (2004) EMBO J , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 147
    • 28844474597 scopus 로고    scopus 로고
    • SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
    • Chen, J.; Zhou, Y.; Mueller-Steiner S.; Chen, L.F.; Kwon, H.; Mucke, L.; Gan, L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J. Biol. Chem., 2005, 280, 40364-74.
    • (2005) J. Biol. Chem , vol.280 , pp. 40364-40374
    • Chen, J.1    Zhou, Y.2    Mueller-Steiner, S.3    Chen, L.F.4    Kwon, H.5    Mucke, L.6    Gan, L.7
  • 149
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • Araki, T.; Sasaki, Y.; Milbrandt, J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science, 2004, 305, 1010-3.
    • (2004) Science , vol.305 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 150
    • 23744474976 scopus 로고    scopus 로고
    • A local mechanism mediates NAD-dependent protection of axon degeneration
    • Wang. J.; Zhai, Q.; Chen, Y.; Lin, E.; Gu, W.; McBurney, M.W.; He, Z. A local mechanism mediates NAD-dependent protection of axon degeneration. J. Cell Biol., 2005, 170. 349-55.
    • (2005) J. Cell Biol , vol.170 , pp. 349-355
    • Wang, J.1    Zhai, Q.2    Chen, Y.3    Lin, E.4    Gu, W.5    McBurney, M.W.6    He, Z.7
  • 152
    • 0038580262 scopus 로고    scopus 로고
    • Transcription factors: New targets for antiallergic therapy
    • Quarcoo, D.; Hamelmann, E. Transcription factors: New targets for antiallergic therapy. Pathobiology, 2002, 70, 293-6.
    • (2002) Pathobiology , vol.70 , pp. 293-296
    • Quarcoo, D.1    Hamelmann, E.2
  • 154
    • 15744368996 scopus 로고    scopus 로고
    • Nuclear receptors as targets for drug development: Crosstalk between peroxisome proliferator-activated receptor gamma and cytokines in bone marrow-derived mesenchymal stem cells
    • Takada, I.; Suzawa, M.; Kato, S. Nuclear receptors as targets for drug development: Crosstalk between peroxisome proliferator-activated receptor gamma and cytokines in bone marrow-derived mesenchymal stem cells. J. Pharmacol. Sci., 2005, 97, 184-9.
    • (2005) J. Pharmacol. Sci , vol.97 , pp. 184-189
    • Takada, I.1    Suzawa, M.2    Kato, S.3
  • 155
    • 33645734522 scopus 로고    scopus 로고
    • Targeting transcription factors for cancer gene therapy
    • Libermann, T.A.; Zerbini, L.F. Targeting transcription factors for cancer gene therapy. Curr. Gene Ther., 2006, 6, 17-33.
    • (2006) Curr. Gene Ther , vol.6 , pp. 17-33
    • Libermann, T.A.1    Zerbini, L.F.2
  • 156
    • 33846583673 scopus 로고    scopus 로고
    • SIR2: A potential target for calorie restriction mimetics
    • Chen, D.; Guarente, L. SIR2: A potential target for calorie restriction mimetics. Trends Mol. Med., 2007, 13, 64-71.
    • (2007) Trends Mol. Med , vol.13 , pp. 64-71
    • Chen, D.1    Guarente, L.2
  • 157
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur, J.A.; Sinclair, D.A. Therapeutic potential of resveratrol: The in vivo evidence. Nat. Rev. Drug Discov., 2006, 5, 493-506.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 159
  • 160
    • 31944450272 scopus 로고    scopus 로고
    • Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate
    • Valenzano, D.R.; Terzibasi, E.; Genade, T.; Cattaneo, A.; Domenici, L.; Cellerino, A. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr. Biol., 2006, 16, 296-300.
    • (2006) Curr. Biol , vol.16 , pp. 296-300
    • Valenzano, D.R.1    Terzibasi, E.2    Genade, T.3    Cattaneo, A.4    Domenici, L.5    Cellerino, A.6
  • 163
    • 0029058728 scopus 로고
    • The spin-trap N-tert-alphaphenyl-butylnitrone prolongs the life span of the senescence accelerated mouse
    • Edamatsu, R.; Mori, A.; Packer, L. The spin-trap N-tert-alphaphenyl-butylnitrone prolongs the life span of the senescence accelerated mouse. Biochem. Biophys. Res. Comm. 1995, 211, 847-9.
    • (1995) Biochem. Biophys. Res. Comm , vol.211 , pp. 847-849
    • Edamatsu, R.1    Mori, A.2    Packer, L.3
  • 164
    • 0032038894 scopus 로고    scopus 로고
    • A spin trap, N-tert-butyl-alphalhenylnitrone extends the life span of mice
    • Saito, K.; Yoshioka, H.; Cutler, R.G. A spin trap, N-tert-butyl-alphalhenylnitrone extends the life span of mice. Biosci. Biotechnol. Biochem., 1998, 62, 792-4.
    • (1998) Biosci. Biotechnol. Biochem , vol.62 , pp. 792-794
    • Saito, K.1    Yoshioka, H.2    Cutler, R.G.3
  • 165
    • 0026409177 scopus 로고
    • The free radical trapping agent N-tert.-butyl-alpha-phenylnitrone (PBN) attenuates cerebral ischaemic injury in gerbils
    • Clough-Helfman C.; Phillis, J.W. The free radical trapping agent N-tert.-butyl-alpha-phenylnitrone (PBN) attenuates cerebral ischaemic injury in gerbils. Free Rad. Res. Comm., 1991, 15, 177-86.
    • (1991) Free Rad. Res. Comm , vol.15 , pp. 177-186
    • Clough-Helfman, C.1    Phillis, J.W.2
  • 166
    • 0002654027 scopus 로고
    • Protective action of nitrone based free radical traps against oxidative damage of the central nervous system
    • Chapman, C.A, Olanow, C.W, Jenner, P, Youssim, M. Eds; Academic Press: London
    • Floyd, R.A.; Carney, J.M. Protective action of nitrone based free radical traps against oxidative damage of the central nervous system. In: Neuroprotective approaches in the treatment of Parkinson's disease and other neurodegenerative disorders. Chapman, C.A.; Olanow, C.W.; Jenner, P.; Youssim, M. Eds; Academic Press: London, 1995; pp. 69-90.
    • (1995) Neuroprotective approaches in the treatment of Parkinson's disease and other neurodegenerative disorders , pp. 69-90
    • Floyd, R.A.1    Carney, J.M.2
  • 167
    • 0020659023 scopus 로고
    • Effect of age and diet on insulin secretion and insulin action in the rat
    • Reaven, G.M.; Wright, D.; Mondon, C.E.; Solomon, R.; Ho, H. Effect of age and diet on insulin secretion and insulin action in the rat. Diabetes, 1983, 32, 175-80.
    • (1983) Diabetes , vol.32 , pp. 175-180
    • Reaven, G.M.1    Wright, D.2    Mondon, C.E.3    Solomon, R.4    Ho, H.5
  • 169
    • 0000093948 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose feeding in rats mimics physiological effect of caloric restriction
    • Lane, M.A.; Ingram, D.K.; Roth, G.S. 2-deoxy-D-glucose feeding in rats mimics physiological effect of caloric restriction. J. Anti Aging Med., 1998, 1, 327-337.
    • (1998) J. Anti Aging Med , vol.1 , pp. 327-337
    • Lane, M.A.1    Ingram, D.K.2    Roth, G.S.3
  • 170
    • 0038718723 scopus 로고    scopus 로고
    • Intermittent fasting and dietary supplementation with 2-deoxy-D-glucose improve functional and metabolic cardiovascular risk factors in rats
    • Wan, R.; Camandola, S.; Mattson, M.P. Intermittent fasting and dietary supplementation with 2-deoxy-D-glucose improve functional and metabolic cardiovascular risk factors in rats. FASEB J., 2003, 17, 1133-4.
    • (2003) FASEB J , vol.17 , pp. 1133-1134
    • Wan, R.1    Camandola, S.2    Mattson, M.P.3
  • 171
    • 36649019357 scopus 로고    scopus 로고
    • The development of tolerance to drugs that suppress food intake
    • Fernstrom, J.D.; Choi, S. The development of tolerance to drugs that suppress food intake. Pharmacol. Ther., 2008, 117, 105-22.
    • (2008) Pharmacol. Ther , vol.117 , pp. 105-122
    • Fernstrom, J.D.1    Choi, S.2
  • 172
    • 33748078481 scopus 로고    scopus 로고
    • Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: Preclinical and clinical data
    • Carai, M.A.; Colombo, G.; Maccioni, P.; Gessa, G.L. Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: Preclinical and clinical data. CNS Drug Rev., 2006, 12, 91-9.
    • (2006) CNS Drug Rev , vol.12 , pp. 91-99
    • Carai, M.A.1    Colombo, G.2    Maccioni, P.3    Gessa, G.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.