메뉴 건너뛰기




Volumn 67, Issue 6, 2005, Pages 482-491

Neuroprotective potential of dietary restriction against kainate-induced excitotoxicity in adult male Wistar rats

Author keywords

Dietary restriction; HSP 70; Kainate; Neuroprotection; Oxidative stress; Seizures

Indexed keywords

ANTIOXIDANT; HEAT SHOCK PROTEIN 70; KAINIC ACID;

EID: 26244443441     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2005.07.015     Document Type: Article
Times cited : (58)

References (56)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • L. Packer Academic press New York
    • H. Aebi Catalase in vitro L. Packer Methods in Enzymology vol. 105 1984 Academic press New York 121 126
    • (1984) Methods in Enzymology , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 0030564954 scopus 로고    scopus 로고
    • The inducible 70,000 molecular/weight heat shock protein is expressed in degenerating dentate hilus and piriform cortex after systemic administration of kainic acid in the rat
    • J.N. Armstrong, J.C.L. Plumier, and E. Rodriguez-Farre The inducible 70,000 molecular/weight heat shock protein is expressed in degenerating dentate hilus and piriform cortex after systemic administration of kainic acid in the rat Neuroscience 74 1996 685 693
    • (1996) Neuroscience , vol.74 , pp. 685-693
    • Armstrong, J.N.1    Plumier, J.C.L.2    Rodriguez-Farre, E.3
  • 3
    • 0035182221 scopus 로고    scopus 로고
    • Stress management - Heat shock protein-70 and the regulation of apoptosis
    • H.M. Beere, and D.R. Green Stress management - heat shock protein-70 and the regulation of apoptosis Trends Cell Biol. 11 2001 6 10
    • (2001) Trends Cell Biol. , vol.11 , pp. 6-10
    • Beere, H.M.1    Green, D.R.2
  • 4
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • L. Packer Academic Press New York
    • J.A. Beuge, and A.D. Aust Microsomal lipid peroxidation L. Packer Methods in Enzymology vol. 52 1978 Academic Press New York 302 310
    • (1978) Methods in Enzymology , vol.52 , pp. 302-310
    • Beuge, J.A.1    Aust, A.D.2
  • 5
    • 0029153913 scopus 로고
    • Apoptosis and necrosis, two distinct events induced, respectively, by mild and intense insults with NMDA or nitric oxide/superoxide in cortical cell cultures
    • E. Bonfoco, D. Krainc, M. Ankarcrona, P. Nicotera, and S.A. Lipton Apoptosis and necrosis, two distinct events induced, respectively, by mild and intense insults with NMDA or nitric oxide/superoxide in cortical cell cultures Proc. Natl. Acad. Sci. U.S.A. 92 1995 7162 7166
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 6
    • 0032925851 scopus 로고    scopus 로고
    • Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
    • A.J. Bruce-Keller, G. Umberger, R. McFall, and M.P. Mattson Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults Ann. Neurol. 45 1999 8 15
    • (1999) Ann. Neurol. , vol.45 , pp. 8-15
    • Bruce-Keller, A.J.1    Umberger, G.2    McFall, R.3    Mattson, M.P.4
  • 8
    • 0035845492 scopus 로고    scopus 로고
    • Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice
    • S.X. Cao, J.M. Dhahbi, P.L. Mote, and S.R. Spindler Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice Proc. Natl. Acad. Sci. U.S.A. 98 2001 10630 10635
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 10630-10635
    • Cao, S.X.1    Dhahbi, J.M.2    Mote, P.L.3    Spindler, S.R.4
  • 9
    • 1342279434 scopus 로고    scopus 로고
    • Dietary restriction protects from neurodegeneration in animal models of excitotoxicity
    • A. Contestabile, E. Ciani, and A. Contestabile Dietary restriction protects from neurodegeneration in animal models of excitotoxicity Brain Res. 1002 2004 162 166
    • (2004) Brain Res. , vol.1002 , pp. 162-166
    • Contestabile, A.1    Ciani, E.2    Contestabile, A.3
  • 10
    • 0019794534 scopus 로고
    • Relative role of caloric restriction and exercise training upon susceptibility to isoproterenol-induced myocardial infarction in male rats
    • D.L. Crandall, R.P. Feirer, D.R. Griffith, and D.C. Beitz Relative role of caloric restriction and exercise training upon susceptibility to isoproterenol-induced myocardial infarction in male rats Am. J. Clin. Nutr. 34 1981 841 847
    • (1981) Am. J. Clin. Nutr. , vol.34 , pp. 841-847
    • Crandall, D.L.1    Feirer, R.P.2    Griffith, D.R.3    Beitz, D.C.4
  • 11
    • 0034703590 scopus 로고    scopus 로고
    • Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats
    • F. Dal-Pizzol, F. Klamt, M.M.R. Vianna, N. Schroder, J. Quevedo, M.S. Benfato, J.C.F. Moreira, and R. Walz Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats Neurosci. Lett. 291 2000 179 182
    • (2000) Neurosci. Lett. , vol.291 , pp. 179-182
    • Dal-Pizzol, F.1    Klamt, F.2    Vianna, M.M.R.3    Schroder, N.4    Quevedo, J.5    Benfato, M.S.6    Moreira, J.C.F.7    Walz, R.8
  • 12
    • 0037418339 scopus 로고    scopus 로고
    • Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
    • W. Duan, Z. Guo, H. Jiang, M. Ware, X.J. Li, and M.P. Mattson Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice Proc. Natl. Acad. Sci. U.S.A. 100 2003 2911 2916
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 2911-2916
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Li, X.J.5    Mattson, M.P.6
  • 13
    • 0033566286 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
    • W. Duan, and M.P. Mattson Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease J. Neurosci. Res. 57 1999 195 206
    • (1999) J. Neurosci. Res. , vol.57 , pp. 195-206
    • Duan, W.1    Mattson, M.P.2
  • 14
    • 0021288821 scopus 로고
    • Assays of glutathione peroxidase
    • L. Packer Academic press New York
    • L. Flohe, and W.A. Gunzler Assays of glutathione peroxidase L. Packer Methods in Enzymology vol. 105 1984 Academic press New York 114 121
    • (1984) Methods in Enzymology , vol.105 , pp. 114-121
    • Flohe, L.1    Gunzler, W.A.2
  • 15
    • 0028106136 scopus 로고
    • The temporal relationship between hepatic GSH loss, heme oxygenase induction, and cytochrome P450 loss following intraperitoneal aluminium administration to mice
    • B. Fulton, and E.H. Jeffery The temporal relationship between hepatic GSH loss, heme oxygenase induction, and cytochrome P450 loss following intraperitoneal aluminium administration to mice Toxicol. Appl. Pharmacol. 127 1994 291 297
    • (1994) Toxicol. Appl. Pharmacol. , vol.127 , pp. 291-297
    • Fulton, B.1    Jeffery, E.H.2
  • 16
    • 0026011632 scopus 로고
    • Superoxide sensitivity of Escherichia coli 6-phosphogluconate dehydrogenase
    • P.R. Gardner, and I. Fridovich Superoxide sensitivity of Escherichia coli 6-phosphogluconate dehydrogenase J. Biol. Chem. 266 1991 1478 1483
    • (1991) J. Biol. Chem. , vol.266 , pp. 1478-1483
    • Gardner, P.R.1    Fridovich, I.2
  • 17
    • 0033931753 scopus 로고    scopus 로고
    • The relationship between stress protein induction and the oxidative defense system in the rat hippocampus following kainic acid administration
    • E.A. Gilberti, and L.D. Trombetta The relationship between stress protein induction and the oxidative defense system in the rat hippocampus following kainic acid administration Toxicol. Lett. 116 2000 17 26
    • (2000) Toxicol. Lett. , vol.116 , pp. 17-26
    • Gilberti, E.A.1    Trombetta, L.D.2
  • 19
    • 84996120592 scopus 로고
    • Oxidant and the central nervous system, some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic brain injury or stroke?
    • B. Halliwell Oxidant and the central nervous system, some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic brain injury or stroke? Acta Neurol. Scand. Suppl. 126 1989 23 33
    • (1989) Acta Neurol. Scand. Suppl. , vol.126 , pp. 23-33
    • Halliwell, B.1
  • 21
    • 0029870841 scopus 로고    scopus 로고
    • Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1
    • A.R. Heydari, S. You, R. Takahashi, A. Gutsmann, K.D. Sarge, and A. Richardson Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1 Dev. Genet. 18 1996 114 124
    • (1996) Dev. Genet. , vol.18 , pp. 114-124
    • Heydari, A.R.1    You, S.2    Takahashi, R.3    Gutsmann, A.4    Sarge, K.D.5    Richardson, A.6
  • 22
    • 0030872357 scopus 로고    scopus 로고
    • Kainate-induced hippocampal damage is attenuated in superoxide dismutase transgenic mice
    • H. Hirata, and J.L. Cadet Kainate-induced hippocampal damage is attenuated in superoxide dismutase transgenic mice Mol. Brain Res. 48 1997 145 148
    • (1997) Mol. Brain Res. , vol.48 , pp. 145-148
    • Hirata, H.1    Cadet, J.L.2
  • 23
    • 0017804313 scopus 로고
    • Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutases
    • Y. Kono Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutases Arch. Biochem. Biophys. 186 1978 189 195
    • (1978) Arch. Biochem. Biophys. , vol.186 , pp. 189-195
    • Kono, Y.1
  • 24
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 25
    • 0029586101 scopus 로고
    • Cell stress genes and neuronal protection
    • D.S. Latchman Cell stress genes and neuronal protection Neuropathol. Appl. Neurobiol. 21 1995 475 477
    • (1995) Neuropathol. Appl. Neurobiol. , vol.21 , pp. 475-477
    • Latchman, D.S.1
  • 26
    • 0346098178 scopus 로고    scopus 로고
    • Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice
    • J. Lee, W.W. Auyeung, and M.P. Mattson Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice Neuromol. Med. 4 2003 179 195
    • (2003) Neuromol. Med. , vol.4 , pp. 179-195
    • Lee, J.1    Auyeung, W.W.2    Mattson, M.P.3
  • 27
    • 0033168080 scopus 로고    scopus 로고
    • 2-Deoxy-d-glucose protects hippocampal neurons against excitotoxic and oxidative injury, evidence for the involvement of stress proteins
    • J. Lee, A.J. Bruce-keller, Y. Kruman, S.L. Chan, and M.P. Mattson 2-Deoxy-d-glucose protects hippocampal neurons against excitotoxic and oxidative injury, evidence for the involvement of stress proteins J. Neurosci. Res. 57 1999 48 61
    • (1999) J. Neurosci. Res. , vol.57 , pp. 48-61
    • Lee, J.1    Bruce-Keller, A.J.2    Kruman, Y.3    Chan, S.L.4    Mattson, M.P.5
  • 28
    • 0034669186 scopus 로고    scopus 로고
    • Mitochondrial superoxide production in kainate induced hippocampal damage
    • L.P. Liang, Y.S. Ho, and M. Patel Mitochondrial superoxide production in kainate induced hippocampal damage Neuroscience 101 2000 563 570
    • (2000) Neuroscience , vol.101 , pp. 563-570
    • Liang, L.P.1    Ho, Y.S.2    Patel, M.3
  • 29
    • 0034703217 scopus 로고    scopus 로고
    • Requirment of NAD and SIR2 for lifespan extension by calorie restriction in Saccharomyces cerevisiae
    • S.J. Lin, P.A. Defossez, and L. Guarente Requirment of NAD and SIR2 for lifespan extension by calorie restriction in Saccharomyces cerevisiae Science 289 2000 2126 2128
    • (2000) Science , vol.289 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 30
    • 0028044860 scopus 로고
    • Increased expression of mRNA encoding calbindin-D28k, the glucose related proteins, or the 72 heat shock protein in three models of acute CNS injury
    • D.H. Lowenstein, R.P. Gwinn, M.S. Seren, R.P. Simon, and T.K. Mclntosh Increased expression of mRNA encoding calbindin-D28k, the glucose related proteins, or the 72 heat shock protein in three models of acute CNS injury Mol. Brain Res. 22 1994 299 308
    • (1994) Mol. Brain Res. , vol.22 , pp. 299-308
    • Lowenstein, D.H.1    Gwinn, R.P.2    Seren, M.S.3    Simon, R.P.4    McLntosh, T.K.5
  • 31
    • 0025077712 scopus 로고
    • The pattern of 72-kDa heat shock protein like immunoreactivity in the rat brain following flurothyl-induced status epilepticus
    • D.H. Lowenstein, R.P. Simon, and F.R. Sharp The pattern of 72-kDa heat shock protein like immunoreactivity in the rat brain following flurothyl-induced status epilepticus Brain Res. 531 1990 173 182
    • (1990) Brain Res. , vol.531 , pp. 173-182
    • Lowenstein, D.H.1    Simon, R.P.2    Sharp, F.R.3
  • 32
    • 19944427435 scopus 로고    scopus 로고
    • Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease
    • N. Maswood, J. Young, E. Tilmont, Z. Zhang, D.M. Gash, and D.K. Ingram Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease Proc. Natl. Acad. Sci. U.S.A. 101 2004 18171 18176
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 18171-18176
    • Maswood, N.1    Young, J.2    Tilmont, E.3    Zhang, Z.4    Gash, D.M.5    Ingram, D.K.6
  • 33
    • 0037314445 scopus 로고    scopus 로고
    • Meal size and frequency affect neuronal plasticity and vulnerability to disease, cellular and molecular mechanisms
    • M.P. Mattson, W. Duan, and Z. Guo Meal size and frequency affect neuronal plasticity and vulnerability to disease, cellular and molecular mechanisms J. Neurochem. 84 2003 417 431
    • (2003) J. Neurochem. , vol.84 , pp. 417-431
    • Mattson, M.P.1    Duan, W.2    Guo, Z.3
  • 34
    • 0030915211 scopus 로고    scopus 로고
    • Physical activity as a factor in the action of dietary restriction on aging: Effects in Fisher 344
    • R.J. McCarter, I. Shimokawa, Y. Ikeno, Y. Higami, G.B. Hubbard, B.P. Yu, and C.A. McMahan Physical activity as a factor in the action of dietary restriction on aging: effects in Fisher 344 Aging 9 1997 73 79
    • (1997) Aging , vol.9 , pp. 73-79
    • McCarter, R.J.1    Shimokawa, I.2    Ikeno, Y.3    Higami, Y.4    Hubbard, G.B.5    Yu, B.P.6    McMahan, C.A.7
  • 36
    • 0028861824 scopus 로고
    • Kainic acid induced heat shock protein 70, mRNA and protein expression is inhibited by MK-801 in certain rat brain regions
    • A.M. Planas, M.A. Soriano, I. Ferrer, and F.E. Rodriguez Kainic acid induced heat shock protein 70, mRNA and protein expression is inhibited by MK-801 in certain rat brain regions Eur. J. Neurosci. 7 1995 293 304
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 293-304
    • Planas, A.M.1    Soriano, M.A.2    Ferrer, I.3    Rodriguez, F.E.4
  • 37
    • 0001883841 scopus 로고    scopus 로고
    • Molecular mechanism of brain aging and neurodegenerative disorders, lessons from dietary restriction
    • T.A. Prolla, and M.P. Mattson Molecular mechanism of brain aging and neurodegenerative disorders, lessons from dietary restriction Trends Neurosci. 24 2001 521 531
    • (2001) Trends Neurosci. , vol.24 , pp. 521-531
    • Prolla, T.A.1    Mattson, M.P.2
  • 38
    • 0034883512 scopus 로고    scopus 로고
    • Dependence of excitotoxicity neurodegeneration on mitochondrial aconitase inactivation
    • L. Qing-You, C. Pederson, B.J. Day, and M. Patel Dependence of excitotoxicity neurodegeneration on mitochondrial aconitase inactivation J. Neurochem. 78 2001 746 755
    • (2001) J. Neurochem. , vol.78 , pp. 746-755
    • Qing-You, L.1    Pederson, C.2    Day, B.J.3    Patel, M.4
  • 40
    • 0029750727 scopus 로고    scopus 로고
    • 2-Cyclopentene-1. a new inducer of heat shock protein 70 with antiviral activity
    • G. Rossi, M.G. Elia, and Santoro 2-Cyclopentene-1. A new inducer of heat shock protein 70 with antiviral activity J. Biol. Chem. 271 1996 32192 32196
    • (1996) J. Biol. Chem. , vol.271 , pp. 32192-32196
    • Rossi, G.1    Elia, M.G.2    Santoro3
  • 41
    • 0037008501 scopus 로고    scopus 로고
    • Biomarkers of Caloric restriction may predict longevity in humans
    • G.S. Roth, M.A. Lane, D.K. Ingram, and J.A. Mattson Biomarkers of Caloric restriction may predict longevity in humans Science 297 2002 811
    • (2002) Science , vol.297 , pp. 811
    • Roth, G.S.1    Lane, M.A.2    Ingram, D.K.3    Mattson, J.A.4
  • 43
    • 0030592803 scopus 로고    scopus 로고
    • HSP 70 is essential to the neuroprotective effect of heat-shock
    • K. Sato, H. Saito, and N. Matsuki HSP 70 is essential to the neuroprotective effect of heat-shock Brain Res. 740 1996
    • (1996) Brain Res. , vol.740
    • Sato, K.1    Saito, H.2    Matsuki, N.3
  • 44
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to HSP 90
    • S. Sato, N. Fujita, and T. Tsuruo Modulation of Akt kinase activity by binding to HSP 90 Proc. Natl. Acad. Sci. U.S.A. 97 2000 10832 10837
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 45
    • 0014428865 scopus 로고
    • Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellman's reagent
    • J. Sedlak, and R.H. Lindsay Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellman's reagent Anal. Biochem. 25 1968 192 205
    • (1968) Anal. Biochem. , vol.25 , pp. 192-205
    • Sedlak, J.1    Lindsay, R.H.2
  • 46
    • 0026721889 scopus 로고
    • Heat shock protein expression in vulnerable cells of the rat hippocampus as an indicator of excitotoxin-induced neuronal stress
    • R.S. Sloviter, and D.H. Lowenstein Heat shock protein expression in vulnerable cells of the rat hippocampus as an indicator of excitotoxin-induced neuronal stress J. Neurosci. 12 1992 3004 3009
    • (1992) J. Neurosci. , vol.12 , pp. 3004-3009
    • Sloviter, R.S.1    Lowenstein, D.H.2
  • 47
    • 0342680006 scopus 로고    scopus 로고
    • Food and metabolic signaling defects in a Caenorhabditis elegans serotonin-synthesis mutant
    • J.Y. Sze, M. Victor, C. Loer, Y. Shi, and G. Ruvkun Food and metabolic signaling defects in a Caenorhabditis elegans serotonin-synthesis mutant Nature 403 2000 560 564
    • (2000) Nature , vol.403 , pp. 560-564
    • Sze, J.Y.1    Victor, M.2    Loer, C.3    Shi, Y.4    Ruvkun, G.5
  • 48
    • 0036460123 scopus 로고    scopus 로고
    • Glutamate excess and free radical formation during and following kainic acid-induced status epilepticus
    • Y. Ueda, H. Yokoyama, A. Nakajima, J. Tokumaru, T. Doi, and Y. Mitsuyama Glutamate excess and free radical formation during and following kainic acid-induced status epilepticus Exp. Brain Res. 147 2002 219 226
    • (2002) Exp. Brain Res. , vol.147 , pp. 219-226
    • Ueda, Y.1    Yokoyama, H.2    Nakajima, A.3    Tokumaru, J.4    Doi, T.5    Mitsuyama, Y.6
  • 49
    • 0024590250 scopus 로고
    • Induction of stress protein HSP 70 in nerve cells after status epilepticus in the rat
    • K. Vass, M.L. Berger, T.S. Nowak Jr., W.J. Welch, and H. Lassmann Induction of stress protein HSP 70 in nerve cells after status epilepticus in the rat Neurosci. Lett. 100 1989 259 264
    • (1989) Neurosci. Lett. , vol.100 , pp. 259-264
    • Vass, K.1    Berger, M.L.2    Nowak Jr., T.S.3    Welch, W.J.4    Lassmann, H.5
  • 51
    • 0026460892 scopus 로고
    • Mammalian stress response, cell physiology, structure/function of stress proteins, and implications for medicine and disease
    • W.J. Welch Mammalian stress response, cell physiology, structure/function of stress proteins, and implications for medicine and disease Physiol. Rev. 72 1992 1063 1081
    • (1992) Physiol. Rev. , vol.72 , pp. 1063-1081
    • Welch, W.J.1
  • 54
    • 0001611514 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome, evidence for a preconditioning mechanism
    • Z.F. Yu, and M.P. Mattson Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome, evidence for a preconditioning mechanism J. Neurosci. Res. 57 1999 830 839
    • (1999) J. Neurosci. Res. , vol.57 , pp. 830-839
    • Yu, Z.F.1    Mattson, M.P.2
  • 55
    • 0029973665 scopus 로고    scopus 로고
    • Expression of heat shock protein-70 and limbic seizure-induced neuronal death in the rat brain
    • X. Zhang, A.A. Boulton, and P.H. Yu Expression of heat shock protein-70 and limbic seizure-induced neuronal death in the rat brain Eur. J. Neurosci. 8 1996 1432 1440
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1432-1440
    • Zhang, X.1    Boulton, A.A.2    Yu, P.H.3
  • 56
    • 0033581321 scopus 로고    scopus 로고
    • Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation
    • H. Zhu, Q. Guo, and M.P. Mattson Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation Brain Res. 842 1999 224 229
    • (1999) Brain Res. , vol.842 , pp. 224-229
    • Zhu, H.1    Guo, Q.2    Mattson, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.