Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

Nature Cell Biology

Volumn 2, Issue 8, 2000, Pages 469-475

  Beere, Helen M ^a   Wolf, Beni B ^a   Cain, Kelvin ^d   Mosser, Dick D ^b   Mahboubi, Artin ^a   Kuwana, Tomomi ^a   Tailor, Pankaj ^c   Morimoto, Richard I ^e   Cohen, Gerald M ^d   Green, Douglas R ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

^e NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; ENZYME PRECURSOR; HEAT SHOCK PROTEIN 70;

APOPTOSIS; ARTICLE; CELL FREE SYSTEM; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROCESSING;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BINDING SITES; CASPASE 9; CASPASES; CELL LINE; CELL-FREE SYSTEM; CHROMATOGRAPHY, GEL; CYTOCHROME C GROUP; DEOXYADENINE NUCLEOTIDES; ENZYME ACTIVATION; ENZYME PRECURSORS; HEAT; HSP70 HEAT-SHOCK PROTEINS; HUMANS; JURKAT CELLS; LIGANDS; MACROMOLECULAR SUBSTANCES; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 0034253533     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35019501     Document Type: Article

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