Animal models for target diseases in gene therapy - Using DNA and siRNA delivery strategies

Pharmaceutical Research

Volumn 26, Issue 1, 2009, Pages 1-18

  Blagbrough, Ian S ^a   Zara, Chiara ^a  

^a University of Bath   (United Kingdom)

Author keywords

Efficacy; Gene delivery; Pharmacodynamics; Pharmacokinetics; RNAi

Indexed keywords

ADENOVIRUS VECTOR; ALPHA SARCOGLYCAN; ANTISENSE OLIGONUCLEOTIDE; DENDRIMER; DNA VACCINE; DRUG CARRIER; DYSTROPHIN; ENZYME INHIBITOR; FIBROBLAST GROWTH FACTOR 2; IMMUNOLIPOSOME; INTERLEUKIN 2; INTERLEUKIN 8; LIPOPLEX; LIPOSOME; NANOPARTICLE; OLIGOMER; PARVOVIRUS VECTOR; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR 2; PLASMID DNA; POLYETHYLENEIMINE; POLYLYSINE; RETINOL ACETATE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TRANSFERRIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; UROKINASE; VIRUS GLYCOPROTEIN;

ANIMAL MODEL; AOTUS; CAT; COW; DISEASE MODEL; DOG; DRUG DELIVERY SYSTEM; DUCHENNE MUSCULAR DYSTROPHY; GENE TARGETING; GENE THERAPY; HEART FAILURE; HORSE; HYDRODYNAMICS; LEBER CONGENITAL AMAUROSIS; LIVER FIBROSIS; MACACA; MARMOSET; MICELLE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; RABBIT; RAINBOW TROUT; REVIEW; RNA INTERFERENCE; RODENT; SHEEP; SWINE; ZEBRA FISH;

ANIMALS; CATS; CATTLE; DISEASE MODELS, ANIMAL; DNA; DOGS; DRUG DELIVERY SYSTEMS; FEMALE; FISHES; GENE THERAPY; HORSES; HUMANS; MICE; PREGNANCY; PRIMATES; RATS; RNA, SMALL INTERFERING; SHEEP; SWINE;

EID: 57749169059     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9646-8     Document Type: Review

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