Development of a novel non-human primate model for preclinical gene vector safety studies. Determining the effects of intracerebral HSV-1 inoculation in the common marmoset: A comparative study

Gene Therapy

Volumn 10, Issue 15, 2003, Pages 1225-1233

  Deisboeck, T S ^a   Wakimoto, H ^a,c   Nestler, U ^a,d   Louis, D N ^a   Sehgal, P K ^b   Simon, M ^b   Chiocca, E A ^a   Hochberg, F H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Common marmoset; Herpes simplex virus 1; Intracerebral inoculation; Non human primate model; Owl monkey; Viral encephalitis

Indexed keywords

VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; HERPES; HERPES SIMPLEX VIRUS 1; HISTOPATHOLOGY; INFECTION SENSITIVITY; INOCULATION; MARMOSET; NONHUMAN; POLYMERASE CHAIN REACTION; PRIMATE; PRIORITY JOURNAL; RELIABILITY; SAFETY; SPECIES DIFFERENCE; VIRAL GENE DELIVERY SYSTEM; VIRUS ENCEPHALITIS; VIRUS LOAD; VIRUS SHEDDING; VIRUS STRAIN; WILD TYPE;

ANIMALS; BRAIN; CALLITHRIX; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; KIDNEY; LIVER; MALE; POLYMERASE CHAIN REACTION; SURVIVAL RATE;

ANIMALIA; AOTUS TRIVIRGATUS; CALLITHRIX; CALLITHRIX JACCHUS; DNA VIRUSES; HUMAN HERPESVIRUS 1; MARMOSETS; PRIMATES; SIMPLEXVIRUS; STRIGIFORMES;

EID: 0041672185     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302003     Document Type: Article

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