An In Vivo Orthotopic Canine Model to Evaluate Distribution of Intraprostatic Injectate: Implications for Gene Therapy and Drug Delivery for Prostate Cancer

Urology

Volumn 70, Issue 4, 2007, Pages 822-825

  Kassouf, Wassim ^a   Brown, Gordon A ^a   Shetty, Anil ^a   Hazle, John D ^a   Stafford, R Jason ^a   Rosser, Charles J ^a   Stephens, Clifton ^a   Tinkey, Peggy T ^a   Pisters, Louis L ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM PENTETATE; METHYLENE BLUE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DOG; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; EVALUATION; FEASIBILITY STUDY; GENE THERAPY; IMAGE ANALYSIS; LAPAROTOMY; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSTATE CANCER; RELIABILITY; STUDENT T TEST;

ANIMALS; CONTRAST MEDIA; DOGS; DRUG DELIVERY SYSTEMS; GADOLINIUM DTPA; GENE THERAPY; INJECTIONS; MAGNETIC RESONANCE IMAGING; MALE; METHYLENE BLUE; PROSTATE; PROSTATIC NEOPLASMS;

EID: 35648998461     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2007.06.637     Document Type: Article

References (8)

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2. Pisters L.L., Pettaway C.A., Hossan E., et al. Intraprostatic AD-p53 gene therapy followed by radical prostatectomy: feasibility and preliminary results. Prostate Cancer Prostatic Dis 2 (1999) S27
3. Steiner M.S., and Gingrich J.R. Gene therapy for prostate cancer: where are we now?. J Urol 164 (2000) 1121-1136
4. Harrington K.J., Spitzweg C., Bateman A.R., et al. Gene therapy for prostate cancer: current status and future prospects. J Urol 166 (2001) 1220-1233
5. Pisters L.L., Pettaway C.A., Troncoso P., et al. Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancer. Clin Cancer Res 10 (2004) 2587-2593
6. Rosser C.J., Tanaka N., Stafford R.J., et al. Feasibility to delineate distribution of solution injected intraprostatic using an ex-vivo canine model. Gene Ther Mol Biol 8 (2004) 509-514
7. O'Hara A.J., Howell J.M., Taplin R.H., et al. The spread of transgene expression at the site of gene construct injection. Muscle Nerve 24 (2001) 488-495
8. Lu Y., Carraher J., Zhang Y., et al. Delivery of adenoviral vectors to the prostate for gene therapy. Cancer Gene Ther 6 (1999) 64-72