Adenoviral gene transfer of HCN4 creates a genetic pacemaker in pigs with complete atrioventricular block

Life Sciences

Volumn 80, Issue 19, 2007, Pages 1746-1753

  Cai, Jun ^a   Yi, Fang Fang ^b   Li, Yan Hui ^b   Yang, Xin Chun ^b   Song, Jian ^c   Jiang, Xue Jun ^a   Jiang, Hong ^a   Lin, Guo Sheng ^a   Wang, Wei ^b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

Arrhythmia; Gene therapy; HCN channel; Pacemaker

Indexed keywords

ADENOVIRUS VECTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CATION CHANNEL; GREEN FLUORESCENT PROTEIN; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CATION CHANNEL 4; ISOPRENALINE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATRIOVENTRICULAR BLOCK; BRADYCARDIA; CATHETER ABLATION; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEASIBILITY STUDY; GENE; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HEART ATRIOVENTRICULAR NODE; HEART RATE; HEART RHYTHM; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CATION CHANNEL 4 GENE; MALE; NONHUMAN; PACEMAKER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ADRENERGIC BETA-AGONISTS; ANIMALS; CELL MEMBRANE; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEART BLOCK; HEART RATE; ION CHANNELS; ISOPROTERENOL; MICROSCOPY, CONFOCAL; MUSCLE PROTEINS; RNA, MESSENGER; SUS SCROFA; TRANSFECTION;

SUIDAE;

EID: 34047252011     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.02.006     Document Type: Article

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