Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Analytical and Bioanalytical Chemistry

Volumn 392, Issue 6, 2008, Pages 1093-1108

  Zanger, Ulrich M ^a,b   Turpeinen, Miia ^a,b,c   Klein, Kathrin ^a,b   Schwab, Matthias ^a,b  

^a DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF OULU   (Finland)

Author keywords

Drug metabolism; Functional genomics; Genotype; Mutation; Pharmacogenetics; Phenotype; Single nucleotide polymorphism

Indexed keywords

BIOCHEMISTRY; METABOLISM; NUCLEIC ACIDS; POLYMORPHISM;

DRUG METABOLISM; FUNCTIONAL GENOMICS; GENOTYPE; MUTATION; PHARMACOGENETICS; PHENOTYPE; SINGLE-NUCLEOTIDE POLYMORPHISM;

ANIMAL CELL CULTURE;

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOCHROME P450; PROTON PUMP INHIBITOR; PSYCHOTROPIC AGENT;

BIOTRANSFORMATION; CLASSIFICATION; DRUG DESIGN; GENETICS; GENOMICS; GENOTYPE; HUMAN; METABOLISM; METHODOLOGY; MUTATION; PHARMACEUTICS; PHARMACOGENETICS; PHENOTYPE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

ADRENERGIC BETA-ANTAGONISTS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DESIGN; GENOMICS; GENOTYPE; HUMANS; MUTATION; PHARMACOGENETICS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTON PUMP INHIBITORS; PSYCHOTROPIC DRUGS; TECHNOLOGY, PHARMACEUTICAL;

EID: 54949144309     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-008-2291-6     Document Type: Review

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