메뉴 건너뛰기




Volumn 72, Issue 3, 2006, Pages 267-279

Regulating the regulator: Factors that control levels and activity of the aryl hydrocarbon receptor

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; AH receptor; Aryl hydrocarbon receptor; Dioxin; Expression; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALPHA NAPHTHOFLAVONE; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; BETA NAPHTHOFLAVONE; DEXAMETHASONE; DIMETHYL SULFOXIDE; ESTRADIOL; GLUCOCORTICOID; PHENOBARBITAL; XENOBIOTIC AGENT;

EID: 33745656989     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.01.007     Document Type: Note
Times cited : (140)

References (99)
  • 1
    • 0017145975 scopus 로고
    • Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase
    • Poland A., Glover E., and Kende A.S. Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase. J Biol Chem 251 (1976) 4936-4946
    • (1976) J Biol Chem , vol.251 , pp. 4936-4946
    • Poland, A.1    Glover, E.2    Kende, A.S.3
  • 2
    • 0018609570 scopus 로고
    • Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation
    • Okey A.B., Bondy G.P., Mason M.E., Kahl G.F., Eisen H.J., Guenthner T.M., et al. Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation. J Biol Chem 254 (1979) 11636-11648
    • (1979) J Biol Chem , vol.254 , pp. 11636-11648
    • Okey, A.B.1    Bondy, G.P.2    Mason, M.E.3    Kahl, G.F.4    Eisen, H.J.5    Guenthner, T.M.6
  • 3
    • 0020010617 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity
    • Poland A., and Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 22 (1982) 517-554
    • (1982) Annu Rev Pharmacol Toxicol , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 4
    • 0034116376 scopus 로고    scopus 로고
    • The PAS superfamily: sensors of environmental and developmental signals
    • Gu Y.Z., Hogenesch J.B., and Bradfield C.A. The PAS superfamily: sensors of environmental and developmental signals. Annu Rev Pharmacol Toxicol 40 (2000) 519-561
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 519-561
    • Gu, Y.Z.1    Hogenesch, J.B.2    Bradfield, C.A.3
  • 5
    • 0034099303 scopus 로고    scopus 로고
    • Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast
    • Elizondo G., Fernandez-Salguero P., Sheikh M.S., Kim G.Y., Fornace A.J., Lee K.S., et al. Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast. Mol Pharmacol 57 (2000) 1056-1063
    • (2000) Mol Pharmacol , vol.57 , pp. 1056-1063
    • Elizondo, G.1    Fernandez-Salguero, P.2    Sheikh, M.S.3    Kim, G.Y.4    Fornace, A.J.5    Lee, K.S.6
  • 6
    • 0037145022 scopus 로고    scopus 로고
    • Role of the aryl hydrocarbon receptor in cell cycle regulation
    • Puga A., Xia Y., and Elferink C. Role of the aryl hydrocarbon receptor in cell cycle regulation. Chem Biol Interact 141 (2002) 117-130
    • (2002) Chem Biol Interact , vol.141 , pp. 117-130
    • Puga, A.1    Xia, Y.2    Elferink, C.3
  • 7
    • 13844298239 scopus 로고    scopus 로고
    • Ah receptor signals cross-talk with multiple developmental pathways
    • Puga A., Tomlinson C.R., and Xia Y. Ah receptor signals cross-talk with multiple developmental pathways. Biochem Pharmacol 69 (2005) 199-207
    • (2005) Biochem Pharmacol , vol.69 , pp. 199-207
    • Puga, A.1    Tomlinson, C.R.2    Xia, Y.3
  • 8
    • 9344230351 scopus 로고    scopus 로고
    • Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development
    • Walisser J.A., Bunger M.K., Glover E., and Bradfield C.A. Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development. Proc Natl Acad Sci USA 101 (2004) 16677-16682
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16677-16682
    • Walisser, J.A.1    Bunger, M.K.2    Glover, E.3    Bradfield, C.A.4
  • 9
    • 27644564007 scopus 로고    scopus 로고
    • Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction
    • Baba T., Mimura J., Nakamura N., Harada N., Yamamoto M., Morohashi K., et al. Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction. Mol Cell Biol 25 (2005) 10040-10051
    • (2005) Mol Cell Biol , vol.25 , pp. 10040-10051
    • Baba, T.1    Mimura, J.2    Nakamura, N.3    Harada, N.4    Yamamoto, M.5    Morohashi, K.6
  • 10
    • 0023236552 scopus 로고
    • Dose-dependent elevation of Ah receptor binding by TCDD in rat liver
    • Sloop T.C., and Lucier G.W. Dose-dependent elevation of Ah receptor binding by TCDD in rat liver. Toxicol Appl Pharmacol 88 (1987) 329-337
    • (1987) Toxicol Appl Pharmacol , vol.88 , pp. 329-337
    • Sloop, T.C.1    Lucier, G.W.2
  • 11
    • 0035880885 scopus 로고    scopus 로고
    • Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effect on aryl hydrocarbon receptor expression in a dioxin-resistance model
    • Franc M.A., Pohjanvirta R., Tuomisto J., and Okey A.B. Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effect on aryl hydrocarbon receptor expression in a dioxin-resistance model. Toxicol Appl Pharmacol 175 (2001) 43-53
    • (2001) Toxicol Appl Pharmacol , vol.175 , pp. 43-53
    • Franc, M.A.1    Pohjanvirta, R.2    Tuomisto, J.3    Okey, A.B.4
  • 12
    • 23044448334 scopus 로고    scopus 로고
    • Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes
    • Kann S., Huang M.Y., Estes C., Reichard J.F., Sartor M.A., Xia Y., et al. Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes. Mol Pharmacol 68 (2005) 336-346
    • (2005) Mol Pharmacol , vol.68 , pp. 336-346
    • Kann, S.1    Huang, M.Y.2    Estes, C.3    Reichard, J.F.4    Sartor, M.A.5    Xia, Y.6
  • 13
    • 19944406443 scopus 로고    scopus 로고
    • CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3′,4,4′,5-pentachlorobiphenyl
    • Wakui S., Yokoo K., Takahashi H., Muto T., Suzuki Y., Kanai Y., et al. CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3′,4,4′,5-pentachlorobiphenyl. Toxicology 211 (2005) 231-241
    • (2005) Toxicology , vol.211 , pp. 231-241
    • Wakui, S.1    Yokoo, K.2    Takahashi, H.3    Muto, T.4    Suzuki, Y.5    Kanai, Y.6
  • 14
    • 0021319045 scopus 로고
    • Elevated binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene to the Ah receptor in hepatic cytosols from phenobarbital-treated rats and mice
    • Okey A.B., and Vella L.M. Elevated binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene to the Ah receptor in hepatic cytosols from phenobarbital-treated rats and mice. Biochem Pharmacol 33 (1984) 531-538
    • (1984) Biochem Pharmacol , vol.33 , pp. 531-538
    • Okey, A.B.1    Vella, L.M.2
  • 15
    • 0036765785 scopus 로고    scopus 로고
    • Nuclear pregnane × receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
    • Maglich J.M., Stoltz C.M., Goodwin B., Hawkins-Brown D., Moore J.T., and Kliewer S.A. Nuclear pregnane × receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol Pharmacol 62 (2002) 638-646
    • (2002) Mol Pharmacol , vol.62 , pp. 638-646
    • Maglich, J.M.1    Stoltz, C.M.2    Goodwin, B.3    Hawkins-Brown, D.4    Moore, J.T.5    Kliewer, S.A.6
  • 16
    • 0022501185 scopus 로고
    • Elevation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) rat hepatic receptor levels by polychlorinated biphenyls. Structure-activity relationships
    • Denomme M.A., Leece B., Li A., Towner R., and Safe S. Elevation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) rat hepatic receptor levels by polychlorinated biphenyls. Structure-activity relationships. Biochem Pharmacol 35 (1986) 277-282
    • (1986) Biochem Pharmacol , vol.35 , pp. 277-282
    • Denomme, M.A.1    Leece, B.2    Li, A.3    Towner, R.4    Safe, S.5
  • 17
    • 0019291033 scopus 로고
    • Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines
    • Okey A.B., Bondy G.P., Mason M.E., Nebert D.W., Forster-Gibson C.J., Muncan J., et al. Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines. J Biol Chem 255 (1980) 11415-11422
    • (1980) J Biol Chem , vol.255 , pp. 11415-11422
    • Okey, A.B.1    Bondy, G.P.2    Mason, M.E.3    Nebert, D.W.4    Forster-Gibson, C.J.5    Muncan, J.6
  • 18
    • 0020024781 scopus 로고
    • Cytosolic and nuclear binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the Ah receptor in extra-hepatic tissues of rats and mice
    • Mason M.E., and Okey A.B. Cytosolic and nuclear binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the Ah receptor in extra-hepatic tissues of rats and mice. Eur J Biochem 123 (1982) 209-215
    • (1982) Eur J Biochem , vol.123 , pp. 209-215
    • Mason, M.E.1    Okey, A.B.2
  • 19
    • 0023617544 scopus 로고
    • Ah receptor in human placenta: stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo[a]pyrene
    • Manchester D.K., Gordon S.K., Golas C.L., Roberts E.A., and Okey A.B. Ah receptor in human placenta: stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo[a]pyrene. Cancer Res 47 (1987) 4861-4868
    • (1987) Cancer Res , vol.47 , pp. 4861-4868
    • Manchester, D.K.1    Gordon, S.K.2    Golas, C.L.3    Roberts, E.A.4    Okey, A.B.5
  • 21
    • 0031874217 scopus 로고    scopus 로고
    • The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis
    • Zaher H., Fernandez-Salguero P.M., Letterio J., Sheikh M.S., Fornace Jr. A.J., Roberts A.B., et al. The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis. Mol Pharmacol 54 (1998) 313-321
    • (1998) Mol Pharmacol , vol.54 , pp. 313-321
    • Zaher, H.1    Fernandez-Salguero, P.M.2    Letterio, J.3    Sheikh, M.S.4    Fornace Jr., A.J.5    Roberts, A.B.6
  • 22
    • 1642279296 scopus 로고    scopus 로고
    • Overexpression of latent transforming growth factor-beta binding protein 1 (LTBP-1) in dioxin receptor-null mouse embryo fibroblasts
    • Santiago-Josefat B., Mulero-Navarro S., Dallas S.L., and Fernandez-Salguero P.M. Overexpression of latent transforming growth factor-beta binding protein 1 (LTBP-1) in dioxin receptor-null mouse embryo fibroblasts. J Cell Sci 117 (2004) 849-859
    • (2004) J Cell Sci , vol.117 , pp. 849-859
    • Santiago-Josefat, B.1    Mulero-Navarro, S.2    Dallas, S.L.3    Fernandez-Salguero, P.M.4
  • 23
    • 0035061761 scopus 로고    scopus 로고
    • Cell-specific regulation of human aryl hydrocarbon receptor expression by transforming growth factor-beta(1)
    • Wolff S., Harper P.A., Wong J.M., Mostert V., Wang Y., and Abel J. Cell-specific regulation of human aryl hydrocarbon receptor expression by transforming growth factor-beta(1). Mol Pharmacol 59 (2001) 716-724
    • (2001) Mol Pharmacol , vol.59 , pp. 716-724
    • Wolff, S.1    Harper, P.A.2    Wong, J.M.3    Mostert, V.4    Wang, Y.5    Abel, J.6
  • 24
    • 16844379900 scopus 로고    scopus 로고
    • Transforming growth factor-beta 3 restores fusion in palatal shelves exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Thomae T.L., Stevens E.A., and Bradfield C.A. Transforming growth factor-beta 3 restores fusion in palatal shelves exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem 280 (2005) 12742-12746
    • (2005) J Biol Chem , vol.280 , pp. 12742-12746
    • Thomae, T.L.1    Stevens, E.A.2    Bradfield, C.A.3
  • 25
    • 0027372414 scopus 로고
    • Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and chromosomal assignment
    • Schmidt J.V., Carver L.A., and Bradfield C.A. Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and chromosomal assignment. J Biol Chem 268 (1993) 22203-22209
    • (1993) J Biol Chem , vol.268 , pp. 22203-22209
    • Schmidt, J.V.1    Carver, L.A.2    Bradfield, C.A.3
  • 30
    • 12444312577 scopus 로고    scopus 로고
    • Effect of TCDD on mRNA expression of genes encoding bHLH/PAS proteins in rat hypothalamus
    • Korkalainen M., Linden J., Tuomisto J., and Pohjanvirta R. Effect of TCDD on mRNA expression of genes encoding bHLH/PAS proteins in rat hypothalamus. Toxicology 208 (2005) 1-11
    • (2005) Toxicology , vol.208 , pp. 1-11
    • Korkalainen, M.1    Linden, J.2    Tuomisto, J.3    Pohjanvirta, R.4
  • 31
    • 2142812857 scopus 로고    scopus 로고
    • Transcriptional regulation of the AhR gene during adipose differentiation
    • Shimba S., Hayashi M., Ohno T., and Tezuka M. Transcriptional regulation of the AhR gene during adipose differentiation. Biol Pharm Bull 26 (2003) 1266-1271
    • (2003) Biol Pharm Bull , vol.26 , pp. 1266-1271
    • Shimba, S.1    Hayashi, M.2    Ohno, T.3    Tezuka, M.4
  • 32
    • 26444493215 scopus 로고    scopus 로고
    • Induction and activation of the aryl hydrocarbon receptor by IL-4 in B cells
    • Tanaka G., Kanaji S., Hirano A., Arima K., Shinagawa A., Goda C., et al. Induction and activation of the aryl hydrocarbon receptor by IL-4 in B cells. Int Immunol 17 (2005) 797-805
    • (2005) Int Immunol , vol.17 , pp. 797-805
    • Tanaka, G.1    Kanaji, S.2    Hirano, A.3    Arima, K.4    Shinagawa, A.5    Goda, C.6
  • 33
    • 0041307080 scopus 로고    scopus 로고
    • Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action
    • Safe S., and Wormke M. Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action. Chem Res Toxicol 16 (2003) 807-816
    • (2003) Chem Res Toxicol , vol.16 , pp. 807-816
    • Safe, S.1    Wormke, M.2
  • 34
    • 0018139079 scopus 로고
    • Pituitary involvement in the sexual differentiation and 3-methylcholanthrene induction of rat liver microsomal monooxygenases
    • Burke M.D., Orrenius S., and Gustafsson J.A. Pituitary involvement in the sexual differentiation and 3-methylcholanthrene induction of rat liver microsomal monooxygenases. Biochem Pharmacol 27 (1978) 1125-1128
    • (1978) Biochem Pharmacol , vol.27 , pp. 1125-1128
    • Burke, M.D.1    Orrenius, S.2    Gustafsson, J.A.3
  • 35
    • 0018569935 scopus 로고
    • Ontogeny of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin and its endocrine independence
    • Carlstedt-Duke J.M., Elfstrom G., Hogberg B., and Gustafsson J.A. Ontogeny of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin and its endocrine independence. Cancer Res 39 (1979) 4653-4656
    • (1979) Cancer Res , vol.39 , pp. 4653-4656
    • Carlstedt-Duke, J.M.1    Elfstrom, G.2    Hogberg, B.3    Gustafsson, J.A.4
  • 36
    • 0036935229 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor expression and function in liver of hypophysectomized male rats
    • Timsit Y.E., Chia F.S.C., Bhathena A., and Riddick D.S. Aromatic hydrocarbon receptor expression and function in liver of hypophysectomized male rats. Toxicol Appl Pharmacol 185 (2002) 136-145
    • (2002) Toxicol Appl Pharmacol , vol.185 , pp. 136-145
    • Timsit, Y.E.1    Chia, F.S.C.2    Bhathena, A.3    Riddick, D.S.4
  • 37
    • 11144262283 scopus 로고    scopus 로고
    • The effect of synthetic glucocorticoid, dexamethasone on CYP1A1 inducibility in adult rat and human hepatocytes
    • Monostory K., Kohalmy K., Prough R.A., Kobori L., and Vereczkey L. The effect of synthetic glucocorticoid, dexamethasone on CYP1A1 inducibility in adult rat and human hepatocytes. FEBS Lett 579 (2005) 229-235
    • (2005) FEBS Lett , vol.579 , pp. 229-235
    • Monostory, K.1    Kohalmy, K.2    Prough, R.A.3    Kobori, L.4    Vereczkey, L.5
  • 38
    • 0033832648 scopus 로고    scopus 로고
    • Stress modulates the enzymatic inducibility by benzo[alpha]pyrene in the rat liver
    • Konstandi M., Johnson E., Lang M.A., Camus-Radon A.M., and Marselos M. Stress modulates the enzymatic inducibility by benzo[alpha]pyrene in the rat liver. Pharmacol Res 42 (2000) 205-211
    • (2000) Pharmacol Res , vol.42 , pp. 205-211
    • Konstandi, M.1    Johnson, E.2    Lang, M.A.3    Camus-Radon, A.M.4    Marselos, M.5
  • 39
    • 0025029021 scopus 로고
    • Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor
    • Wiebel F.J., and Cikryt P. Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor. Chem Biol Interact 76 (1990) 307-320
    • (1990) Chem Biol Interact , vol.76 , pp. 307-320
    • Wiebel, F.J.1    Cikryt, P.2
  • 40
    • 0027937244 scopus 로고
    • Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone
    • Abbott B.D., Perdew G.H., Buckalew A.R., and Birnbaum L.S. Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone. Toxicol Appl Pharmacol 128 (1994) 138-150
    • (1994) Toxicol Appl Pharmacol , vol.128 , pp. 138-150
    • Abbott, B.D.1    Perdew, G.H.2    Buckalew, A.R.3    Birnbaum, L.S.4
  • 41
    • 0031785466 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulation of cytochrome P4501B1 in rat mammary fibroblasts: evidence for transcriptional repression by glucocorticoids
    • Brake P.B., Zhang L., and Jefcoate C.R. Aryl hydrocarbon receptor regulation of cytochrome P4501B1 in rat mammary fibroblasts: evidence for transcriptional repression by glucocorticoids. Mol Pharmacol 54 (1998) 825-833
    • (1998) Mol Pharmacol , vol.54 , pp. 825-833
    • Brake, P.B.1    Zhang, L.2    Jefcoate, C.R.3
  • 42
    • 0022320031 scopus 로고
    • Thyroid hormones modulate the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Rozman K., Rozman T., Scheufler E., Pazdernik T., and Greim H. Thyroid hormones modulate the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). J Toxicol Environ Health 16 (1985) 481-491
    • (1985) J Toxicol Environ Health , vol.16 , pp. 481-491
    • Rozman, K.1    Rozman, T.2    Scheufler, E.3    Pazdernik, T.4    Greim, H.5
  • 43
    • 0022908995 scopus 로고
    • Effects of thyroidectomy on the Ah receptor and enzyme inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver
    • Henry E.C., and Gasiewicz T.A. Effects of thyroidectomy on the Ah receptor and enzyme inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver. Chem Biol Interact 59 (1986) 29-42
    • (1986) Chem Biol Interact , vol.59 , pp. 29-42
    • Henry, E.C.1    Gasiewicz, T.A.2
  • 44
    • 0022358847 scopus 로고
    • Effect of thyroid hormones on liver microsomal enzyme induction in rats exposed to 2,3,7,8,-tetrachlorodibenzo-p-dioxin
    • Rozman K., Hazelton G.A., Klaassen C.D., Arlotto M.P., and Parkinson A. Effect of thyroid hormones on liver microsomal enzyme induction in rats exposed to 2,3,7,8,-tetrachlorodibenzo-p-dioxin. Toxicology 37 (1985) 51-63
    • (1985) Toxicology , vol.37 , pp. 51-63
    • Rozman, K.1    Hazelton, G.A.2    Klaassen, C.D.3    Arlotto, M.P.4    Parkinson, A.5
  • 45
    • 0025904447 scopus 로고
    • Ovarian hormones enhance 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated increases in cell proliferation and preneoplastic foci in a two-stage model for rat hepatocarcinogenesis
    • Lucier G.W., Tritscher A., Goldsworthy T., Foley J., Clark G., Goldstein J., et al. Ovarian hormones enhance 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated increases in cell proliferation and preneoplastic foci in a two-stage model for rat hepatocarcinogenesis. Cancer Res 51 (1991) 1391-1397
    • (1991) Cancer Res , vol.51 , pp. 1391-1397
    • Lucier, G.W.1    Tritscher, A.2    Goldsworthy, T.3    Foley, J.4    Clark, G.5    Goldstein, J.6
  • 46
    • 0029918651 scopus 로고    scopus 로고
    • Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signalling
    • Kharat I., and Saatcioglu F. Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signalling. J Biol Chem 271 (1996) 10533-10537
    • (1996) J Biol Chem , vol.271 , pp. 10533-10537
    • Kharat, I.1    Saatcioglu, F.2
  • 47
    • 0030775162 scopus 로고    scopus 로고
    • Estrogen does not inhibit 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated effects in MCF-7 and Hepa 1c1c7 cells
    • Hoivik D., Willett K., Wilson C., and Safe S. Estrogen does not inhibit 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated effects in MCF-7 and Hepa 1c1c7 cells. J Biol Chem 272 (1997) 30270-30274
    • (1997) J Biol Chem , vol.272 , pp. 30270-30274
    • Hoivik, D.1    Willett, K.2    Wilson, C.3    Safe, S.4
  • 48
    • 0033179445 scopus 로고    scopus 로고
    • Role of estradiol receptor-alpha in differential expression of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible genes in the RL95-2 and KLE human endometrial cancer cell lines
    • Jana N.R., Sarkar S., Ishizuka M., Yonemoto J., Tohyama C., and Sone H. Role of estradiol receptor-alpha in differential expression of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible genes in the RL95-2 and KLE human endometrial cancer cell lines. Arch Biochem Biophys 368 (1999) 31-39
    • (1999) Arch Biochem Biophys , vol.368 , pp. 31-39
    • Jana, N.R.1    Sarkar, S.2    Ishizuka, M.3    Yonemoto, J.4    Tohyama, C.5    Sone, H.6
  • 49
    • 0037100132 scopus 로고    scopus 로고
    • Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line
    • Son D.S., Roby K.F., Rozman K.K., and Terranova P.F. Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line. Toxicology 176 (2002) 229-243
    • (2002) Toxicology , vol.176 , pp. 229-243
    • Son, D.S.1    Roby, K.F.2    Rozman, K.K.3    Terranova, P.F.4
  • 50
    • 0038100188 scopus 로고    scopus 로고
    • Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
    • Ohtake F., Takeyama K., Matsumoto T., Kitagawa H., Yamamoto Y., Nohara K., et al. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423 (2003) 545-550
    • (2003) Nature , vol.423 , pp. 545-550
    • Ohtake, F.1    Takeyama, K.2    Matsumoto, T.3    Kitagawa, H.4    Yamamoto, Y.5    Nohara, K.6
  • 51
    • 20844440300 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters
    • Matthews J., Wihlen B., Thomsen J., and Gustafsson J.A. Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters. Mol Cell Biol 25 (2005) 5317-5328
    • (2005) Mol Cell Biol , vol.25 , pp. 5317-5328
    • Matthews, J.1    Wihlen, B.2    Thomsen, J.3    Gustafsson, J.A.4
  • 52
    • 20444381667 scopus 로고    scopus 로고
    • ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription
    • Beischlag T.V., and Perdew G.H. ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. J Biol Chem 280 (2005) 21607-21611
    • (2005) J Biol Chem , vol.280 , pp. 21607-21611
    • Beischlag, T.V.1    Perdew, G.H.2
  • 54
    • 0037166042 scopus 로고    scopus 로고
    • Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on preimplantation mouse embryos
    • Wu Q., Ohsako S., Baba T., Miyamoto K., and Tohyama C. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on preimplantation mouse embryos. Toxicology 174 (2002) 119-129
    • (2002) Toxicology , vol.174 , pp. 119-129
    • Wu, Q.1    Ohsako, S.2    Baba, T.3    Miyamoto, K.4    Tohyama, C.5
  • 55
    • 0018898233 scopus 로고
    • Ontogenetic expression of regulatory and structural gene products associated with the Ah locus. Comparison of rat, mouse, rabbit and Sigmoden hispedis
    • Kahl G.F., Friederici D.E., Bigelow S.W., Okey A.B., and Nebert D.W. Ontogenetic expression of regulatory and structural gene products associated with the Ah locus. Comparison of rat, mouse, rabbit and Sigmoden hispedis. Dev Pharmacol Ther 1 (1980) 137-162
    • (1980) Dev Pharmacol Ther , vol.1 , pp. 137-162
    • Kahl, G.F.1    Friederici, D.E.2    Bigelow, S.W.3    Okey, A.B.4    Nebert, D.W.5
  • 56
    • 0021345006 scopus 로고
    • Ontogeny of the cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, lung, and thymus
    • Gasiewicz T.A., Ness W.C., and Rucci G. Ontogeny of the cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, lung, and thymus. Biochem Biophys Res Commun 118 (1984) 183-190
    • (1984) Biochem Biophys Res Commun , vol.118 , pp. 183-190
    • Gasiewicz, T.A.1    Ness, W.C.2    Rucci, G.3
  • 57
    • 0344859868 scopus 로고    scopus 로고
    • Ah receptor and ARNT protein and mRNA concentrations in rat prostate: effects of stage of development and 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
    • Sommer R.J., Sojka K.M., Pollenz R.S., Cooke P.S., and Peterson R.E. Ah receptor and ARNT protein and mRNA concentrations in rat prostate: effects of stage of development and 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Toxicol Appl Pharmacol 155 (1999) 177-189
    • (1999) Toxicol Appl Pharmacol , vol.155 , pp. 177-189
    • Sommer, R.J.1    Sojka, K.M.2    Pollenz, R.S.3    Cooke, P.S.4    Peterson, R.E.5
  • 58
    • 17144404543 scopus 로고    scopus 로고
    • Gene expression of drug metabolizing enzymes in adult and aged mouse liver: a modulation by immobilization stress
    • Mikhailova O.N., Gulyaeva L.F., and Filipenko M.L. Gene expression of drug metabolizing enzymes in adult and aged mouse liver: a modulation by immobilization stress. Toxicology 210 (2005) 189-196
    • (2005) Toxicology , vol.210 , pp. 189-196
    • Mikhailova, O.N.1    Gulyaeva, L.F.2    Filipenko, M.L.3
  • 59
    • 0037145023 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptors: diversity and evolution
    • Hahn M.E. Aryl hydrocarbon receptors: diversity and evolution. Chem Biol Interact 141 (2002) 131-160
    • (2002) Chem Biol Interact , vol.141 , pp. 131-160
    • Hahn, M.E.1
  • 60
    • 0032539796 scopus 로고    scopus 로고
    • Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator
    • Powell-Coffman J.A., Bradfield C.A., and Wood W.B. Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator. Proc Natl Acad Sci USA 95 (1998) 2844-2849
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2844-2849
    • Powell-Coffman, J.A.1    Bradfield, C.A.2    Wood, W.B.3
  • 61
    • 0030973864 scopus 로고    scopus 로고
    • POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolution
    • Gruber C.A., Rhee J.M., Gleiberman A., and Turner E.E. POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolution. Mol Cell Biol 17 (1997) 2391-2400
    • (1997) Mol Cell Biol , vol.17 , pp. 2391-2400
    • Gruber, C.A.1    Rhee, J.M.2    Gleiberman, A.3    Turner, E.E.4
  • 62
    • 0032079316 scopus 로고    scopus 로고
    • Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor
    • Duncan D.M., Burgess E.A., and Duncan I. Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor. Genes Dev 12 (1998) 1290-1303
    • (1998) Genes Dev , vol.12 , pp. 1290-1303
    • Duncan, D.M.1    Burgess, E.A.2    Duncan, I.3
  • 63
    • 0032872580 scopus 로고    scopus 로고
    • The spineless-aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila
    • Emmons R.B., Duncan D., Estes P.A., Kiefel P., Mosher J.T., Sonnenfeld M., et al. The spineless-aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila. Development 126 (1999) 3937-3945
    • (1999) Development , vol.126 , pp. 3937-3945
    • Emmons, R.B.1    Duncan, D.2    Estes, P.A.3    Kiefel, P.4    Mosher, J.T.5    Sonnenfeld, M.6
  • 65
    • 0036667370 scopus 로고    scopus 로고
    • Effects of aryl hydrocarbon receptor null mutation and in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on prostate and seminal vesicle development in C57BL/6 mice
    • Lin T.M., Ko K., Moore R.W., Simanainen U., Oberley T.D., and Peterson R.E. Effects of aryl hydrocarbon receptor null mutation and in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on prostate and seminal vesicle development in C57BL/6 mice. Toxicol Sci 68 (2002) 479-487
    • (2002) Toxicol Sci , vol.68 , pp. 479-487
    • Lin, T.M.1    Ko, K.2    Moore, R.W.3    Simanainen, U.4    Oberley, T.D.5    Peterson, R.E.6
  • 66
    • 0032104188 scopus 로고    scopus 로고
    • In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prostate development. 1. Effects on gene expression
    • Roman B.L., and Peterson R.E. In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prostate development. 1. Effects on gene expression. Toxicol Appl Pharmacol 150 (1998) 240-253
    • (1998) Toxicol Appl Pharmacol , vol.150 , pp. 240-253
    • Roman, B.L.1    Peterson, R.E.2
  • 67
    • 0026000191 scopus 로고
    • Downregulation of the Ah receptor in mouse hepatoma cells treated in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Prokipcak R.D., and Okey A.B. Downregulation of the Ah receptor in mouse hepatoma cells treated in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Can J Physiol Pharmacol 69 (1991) 1204-1210
    • (1991) Can J Physiol Pharmacol , vol.69 , pp. 1204-1210
    • Prokipcak, R.D.1    Okey, A.B.2
  • 68
    • 0033579570 scopus 로고    scopus 로고
    • Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway
    • Roberts B.J., and Whitelaw M.L. Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway. J Biol Chem 274 (1999) 36351-36356
    • (1999) J Biol Chem , vol.274 , pp. 36351-36356
    • Roberts, B.J.1    Whitelaw, M.L.2
  • 69
    • 0037145007 scopus 로고    scopus 로고
    • The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation
    • Pollenz R.S. The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation. Chem Biol Interact 141 (2002) 41-61
    • (2002) Chem Biol Interact , vol.141 , pp. 41-61
    • Pollenz, R.S.1
  • 70
    • 0032519879 scopus 로고    scopus 로고
    • Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Giannone J.V., Li W., Probst M., and Okey A.B. Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem Pharmacol 55 (1998) 489-497
    • (1998) Biochem Pharmacol , vol.55 , pp. 489-497
    • Giannone, J.V.1    Li, W.2    Probst, M.3    Okey, A.B.4
  • 71
    • 27544488746 scopus 로고    scopus 로고
    • Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse Ah(b-1) receptor
    • Pollenz R.S., Popat J., and Dougherty E.J. Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse Ah(b-1) receptor. Biochem Pharmacol 70 (2005) 1623-1633
    • (2005) Biochem Pharmacol , vol.70 , pp. 1623-1633
    • Pollenz, R.S.1    Popat, J.2    Dougherty, E.J.3
  • 72
    • 0032899367 scopus 로고    scopus 로고
    • Identification of a novel mechanism of regulation of Ah (dioxin) receptor function
    • Mimura J., Ema M., Sogawa K., and Fujii-Kuriyama Y. Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. Genes Dev 13 (1999) 20-25
    • (1999) Genes Dev , vol.13 , pp. 20-25
    • Mimura, J.1    Ema, M.2    Sogawa, K.3    Fujii-Kuriyama, Y.4
  • 73
    • 0842308115 scopus 로고    scopus 로고
    • Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain
    • Korkalainen M., Tuomisto J., and Pohjanvirta R. Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain. Biochem Biophys Res Commun 315 (2004) 123-131
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 123-131
    • Korkalainen, M.1    Tuomisto, J.2    Pohjanvirta, R.3
  • 75
    • 33745662655 scopus 로고    scopus 로고
    • Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice
    • [Epub ahead of print]
    • Bernshausen T., Jux B., Esser C., Abel J., and Fritsche E. Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice. Arch Toxicol (2005) [Epub ahead of print]
    • (2005) Arch Toxicol
    • Bernshausen, T.1    Jux, B.2    Esser, C.3    Abel, J.4    Fritsche, E.5
  • 76
    • 0347481466 scopus 로고    scopus 로고
    • Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: organ-specific distribution and variable induction patterns in mononuclear cells
    • Yamamoto J., Ihara K., Nakayama H., Hikino S., Satoh K., Kubo N., et al. Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: organ-specific distribution and variable induction patterns in mononuclear cells. Life Sci 74 (2004) 1039-1049
    • (2004) Life Sci , vol.74 , pp. 1039-1049
    • Yamamoto, J.1    Ihara, K.2    Nakayama, H.3    Hikino, S.4    Satoh, K.5    Kubo, N.6
  • 77
    • 0037387905 scopus 로고    scopus 로고
    • Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines
    • Tsuchiya Y., Nakajima M., Itoh S., Iwanari M., and Yokoi T. Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines. Toxicol Sci 72 (2003) 253-259
    • (2003) Toxicol Sci , vol.72 , pp. 253-259
    • Tsuchiya, Y.1    Nakajima, M.2    Itoh, S.3    Iwanari, M.4    Yokoi, T.5
  • 79
    • 20644435582 scopus 로고    scopus 로고
    • Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes
    • Okey A.B., Boutros P.C., and Harper P.A. Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes. Pharmacogenet Genomics 15 (2005) 371-379
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 371-379
    • Okey, A.B.1    Boutros, P.C.2    Harper, P.A.3
  • 80
    • 24644461253 scopus 로고    scopus 로고
    • Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: the case of the aryl hydrocarbon receptor
    • Okey A.B., Franc M.A., Moffat I.D., Tijet N., Boutros P.C., Korkalainen M., et al. Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: the case of the aryl hydrocarbon receptor. Toxicol Appl Pharmacol 207 (2005) S43-S51
    • (2005) Toxicol Appl Pharmacol , vol.207
    • Okey, A.B.1    Franc, M.A.2    Moffat, I.D.3    Tijet, N.4    Boutros, P.C.5    Korkalainen, M.6
  • 81
    • 22944490557 scopus 로고    scopus 로고
    • Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population
    • Koyano S., Saito Y., Fukushima-Uesaka H., Ishida S., Ozawa S., Kamatani N., et al. Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population. Drug Metab Dispos 33 (2005) 1254-1260
    • (2005) Drug Metab Dispos , vol.33 , pp. 1254-1260
    • Koyano, S.1    Saito, Y.2    Fukushima-Uesaka, H.3    Ishida, S.4    Ozawa, S.5    Kamatani, N.6
  • 82
    • 1942501666 scopus 로고    scopus 로고
    • Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele
    • Walisser J.A., Bunger M.K., Glover E., Harstad E.B., and Bradfield C.A. Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele. J Biol Chem 279 (2004) 16326-16331
    • (2004) J Biol Chem , vol.279 , pp. 16326-16331
    • Walisser, J.A.1    Bunger, M.K.2    Glover, E.3    Harstad, E.B.4    Bradfield, C.A.5
  • 83
    • 0032983540 scopus 로고    scopus 로고
    • Biological regulation of receptor-hormone complex concentrations in relation to dose-response assessments for endocrine-active compounds
    • Andersen M.E., and Barton H.A. Biological regulation of receptor-hormone complex concentrations in relation to dose-response assessments for endocrine-active compounds. Toxicol Sci 48 (1999) 38-50
    • (1999) Toxicol Sci , vol.48 , pp. 38-50
    • Andersen, M.E.1    Barton, H.A.2
  • 84
    • 0034725042 scopus 로고    scopus 로고
    • Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide
    • Ma Q., Renzelli A.J., Baldwin K.T., and Antonini J.M. Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide. J Biol Chem 275 (2000) 12676-12683
    • (2000) J Biol Chem , vol.275 , pp. 12676-12683
    • Ma, Q.1    Renzelli, A.J.2    Baldwin, K.T.3    Antonini, J.M.4
  • 85
    • 0037764668 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells
    • Abdelrahim M., Smith III R., and Safe S. Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. Mol Pharmacol 63 (2003) 1373-1381
    • (2003) Mol Pharmacol , vol.63 , pp. 1373-1381
    • Abdelrahim, M.1    Smith III, R.2    Safe, S.3
  • 86
    • 0025055648 scopus 로고
    • Enzyme induction in the cytochrome P-450 system
    • Okey A.B. Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 45 (1990) 241-298
    • (1990) Pharmacol Ther , vol.45 , pp. 241-298
    • Okey, A.B.1
  • 87
    • 2642510760 scopus 로고    scopus 로고
    • Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
    • Nebert D.W., Dalton T.P., Okey A.B., and Gonzalez F.J. Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem 279 (2004) 23847-23850
    • (2004) J Biol Chem , vol.279 , pp. 23847-23850
    • Nebert, D.W.1    Dalton, T.P.2    Okey, A.B.3    Gonzalez, F.J.4
  • 88
    • 0029963257 scopus 로고    scopus 로고
    • The aromatic hydrocarbon receptor modulates the Hepa-1c1c7 cell cycle and differentiated state independently of dioxin
    • Ma Q., and Whitlock Jr. J.P. The aromatic hydrocarbon receptor modulates the Hepa-1c1c7 cell cycle and differentiated state independently of dioxin. Mol Cell Biol 16 (1996) 2144-2150
    • (1996) Mol Cell Biol , vol.16 , pp. 2144-2150
    • Ma, Q.1    Whitlock Jr., J.P.2
  • 89
    • 18044374985 scopus 로고    scopus 로고
    • Ah receptor- and TCDD-mediated liver tumor promotion: clonal selection and expansion of cells evading growth arrest and apoptosis
    • Bock K.W., and Kohle C. Ah receptor- and TCDD-mediated liver tumor promotion: clonal selection and expansion of cells evading growth arrest and apoptosis. Biochem Pharmacol 69 (2005) 1403-1408
    • (2005) Biochem Pharmacol , vol.69 , pp. 1403-1408
    • Bock, K.W.1    Kohle, C.2
  • 90
    • 0036615860 scopus 로고    scopus 로고
    • Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers
    • Safe S., and McDougal A. Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers. Int J Oncol 20 (2002) 1123-1128
    • (2002) Int J Oncol , vol.20 , pp. 1123-1128
    • Safe, S.1    McDougal, A.2
  • 91
    • 1842484230 scopus 로고    scopus 로고
    • The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate
    • Bradshaw T.D., and Westwell A.D. The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate. Curr Med Chem 11 (2004) 1009-1021
    • (2004) Curr Med Chem , vol.11 , pp. 1009-1021
    • Bradshaw, T.D.1    Westwell, A.D.2
  • 92
    • 4444223703 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells
    • Loaiza-Perez A.I., Kenney S., Boswell J., Hollingshead M., Alley M.C., Hose C., et al. Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells. Mol Cancer Ther 3 (2004) 715-725
    • (2004) Mol Cancer Ther , vol.3 , pp. 715-725
    • Loaiza-Perez, A.I.1    Kenney, S.2    Boswell, J.3    Hollingshead, M.4    Alley, M.C.5    Hose, C.6
  • 93
    • 3042695024 scopus 로고    scopus 로고
    • Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a
    • Ray S.S., and Swanson H.I. Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. J Biol Chem 279 (2004) 27187-27193
    • (2004) J Biol Chem , vol.279 , pp. 27187-27193
    • Ray, S.S.1    Swanson, H.I.2
  • 94
    • 1942538298 scopus 로고    scopus 로고
    • Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells
    • Chesire D.R., Dunn T.A., Ewing C.M., Luo J., and Isaacs W.B. Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells. Cancer Res 64 (2004) 2523-2533
    • (2004) Cancer Res , vol.64 , pp. 2523-2533
    • Chesire, D.R.1    Dunn, T.A.2    Ewing, C.M.3    Luo, J.4    Isaacs, W.B.5
  • 95
    • 0037026632 scopus 로고    scopus 로고
    • Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer
    • Koliopanos A., Kleeff J., Xiao Y., Safe S., Zimmermann A., Buchler M.W., et al. Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer. Oncogene 21 (2002) 6059-6070
    • (2002) Oncogene , vol.21 , pp. 6059-6070
    • Koliopanos, A.1    Kleeff, J.2    Xiao, Y.3    Safe, S.4    Zimmermann, A.5    Buchler, M.W.6
  • 96
    • 23744439083 scopus 로고    scopus 로고
    • Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
    • Gunton J.E., Kulkarni R.N., Yim S., Okada T., Hawthorne W.J., Tseng Y.H., et al. Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell 122 (2005) 337-349
    • (2005) Cell , vol.122 , pp. 337-349
    • Gunton, J.E.1    Kulkarni, R.N.2    Yim, S.3    Okada, T.4    Hawthorne, W.J.5    Tseng, Y.H.6
  • 97
    • 27144450537 scopus 로고    scopus 로고
    • Systems biology. Less is more in modeling large genetic networks
    • Bornholdt S. Systems biology. Less is more in modeling large genetic networks. Science 310 (2005) 449-451
    • (2005) Science , vol.310 , pp. 449-451
    • Bornholdt, S.1
  • 98
    • 30044452058 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
    • Tijet N., Boutros P.C., Moffat I.D., Okey A.B., Tuomisto J., and Pohjanvirta R. The aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol Pharmacol 69 (2006) 140-153
    • (2006) Mol Pharmacol , vol.69 , pp. 140-153
    • Tijet, N.1    Boutros, P.C.2    Moffat, I.D.3    Okey, A.B.4    Tuomisto, J.5    Pohjanvirta, R.6
  • 99
    • 21444443478 scopus 로고    scopus 로고
    • MatInspector and beyond: promoter analysis based on transcription factor binding sites
    • Cartharius K., Frech K., Grote K., Klocke B., Haltmeier M., Klingenhoff A., et al. MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics 21 (2005) 2933-2942
    • (2005) Bioinformatics , vol.21 , pp. 2933-2942
    • Cartharius, K.1    Frech, K.2    Grote, K.3    Klocke, B.4    Haltmeier, M.5    Klingenhoff, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.