Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes

Drug Metabolism and Disposition

Volumn 29, Issue 10, 2001, Pages 1263-1268

  Yasui Furukori, Norio ^a   Hidestrand, Mats ^b   Spina, Edoardo ^c   Facciolá, Gabriella ^c   Scordo, Maria Gabriella ^c   Tybring, Gunnel ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; KETOCONAZOLE; OROSOMUCOID; PALIPERIDONE; QUINIDINE; RISPERIDONE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG POTENCY; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIVER MICROSOME; PRIORITY JOURNAL; STEREOCHEMISTRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; DOPAMINE ANTAGONISTS; HUMANS; HYDROXYLATION; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; MOLECULAR CONFORMATION; RECOMBINANT PROTEINS; RISPERIDONE;

EID: 0034829228     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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