Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: Effect on the CYP1A2 inducibility in humans

Journal of Biochemistry

Volumn 125, Issue 4, 1999, Pages 803-808

  Nakajima, Miki ^a,d   Yokoi, Tsuyoshi ^a,d   Mizutani, Mayumi ^a   Kinoshita, Moritoshi ^b   Funayama, Masato ^c   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

Author keywords

Caffeine metabolism; Cigarette smoking; Induction; PCR RFLP

Indexed keywords

ADENINE; CAFFEINE; CYTOCHROME P450 ISOENZYME; GUANINE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DNA FLANKING REGION; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME STRUCTURE; FEMALE; GENE FREQUENCY; GENE INDUCTION; GENETIC POLYMORPHISM; HUMAN; MALE; NORMAL HUMAN; POINT MUTATION; PROTEIN DNA BINDING; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

EID: 0032929010     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022352     Document Type: Article

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