Metabolism of the antidepressant mirtazapine in vitro: Contribution of cytochromes P-450 1A2, 2D6, and 3A4

Drug Metabolism and Disposition

Volumn 28, Issue 10, 2000, Pages 1168-1175

  Störmer, Elke ^a   Von Moltke, Lisa L ^a   Shader, Richard I ^a   Greenblatt, David J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; KETOCONAZOLE; MIRTAZAPINE; PHENACETIN O DEETHYLASE; QUINIDINE; UNCLASSIFIED DRUG;

ARTICLE; DEMETHYLATION; DRUG CLEARANCE; DRUG INHIBITION; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME POLYMORPHISM; GENETIC POLYMORPHISM; GLUCURONIDATION; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIVER MICROSOME; OXIDATION; PREDICTION; PRIORITY JOURNAL;

ANTIDEPRESSIVE AGENTS, TRICYCLIC; BENZOFLAVONES; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; HYDROXYLATION; ISOENZYMES; METHYLATION; MIANSERIN; MICROSOMES, LIVER; OXIDATION-REDUCTION; QUINIDINE; RECOMBINANT PROTEINS;

EID: 0033810675     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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