-
2
-
-
0029056606
-
1A-mediated serotonergic neurotransmission
-
1A-mediated serotonergic neurotransmission. CNS Drugs 1995; 4 Suppl. 1: 29-38
-
(1995)
CNS Drugs
, vol.4
, Issue.SUPPL. 1
, pp. 29-38
-
-
De Boer, T.1
Ruigt, G.S.F.2
-
3
-
-
0029070861
-
The effects of mirtazapine on interactions between central noradrenergic and serotonergic systems
-
3. De Montigny C, Haddjeri N, Mongeau R, et al. The effects of mirtazapine on interactions between central noradrenergic and serotonergic systems. CNS Drugs 1995; 4 Suppl. 1: 13-17
-
(1995)
CNS Drugs
, vol.4
, Issue.SUPPL. 1
, pp. 13-17
-
-
De Montigny, C.1
Haddjeri, N.2
Mongeau, R.3
-
4
-
-
0028798939
-
A double-blind comparison of Org 3770, amitriptyline and placebo in major depression
-
4. Bremner JD. A double-blind comparison of Org 3770, amitriptyline and placebo in major depression. J Clin Psychiatry 1995; 56: 519-25
-
(1995)
J Clin Psychiatry
, vol.56
, pp. 519-525
-
-
Bremner, J.D.1
-
5
-
-
0029070521
-
A double-blind placebo controlled study of Org 3770 in depressed outpatients
-
5. Claghorn JL, Lessem MD. A double-blind placebo controlled study of Org 3770 in depressed outpatients. J Affective Disorders 1995; 34: 165-71
-
(1995)
J Affective Disorders
, vol.34
, pp. 165-171
-
-
Claghorn, J.L.1
Lessem, M.D.2
-
6
-
-
0013679959
-
Wirksamkeit under verträglichkeit von Org 3770 bei patienten mit einer major depression
-
6. Sitsen JMA, Zivkov M, Dieterle D. Wirksamkeit under Verträglichkeit von Org 3770 bei Patienten mit einer Major Depression. Psychopharmakotherapie 1995; 2: 68-71
-
(1995)
Psychopharmakotherapie
, vol.2
, pp. 68-71
-
-
Sitsen, J.M.A.1
Zivkov, M.2
Dieterle, D.3
-
7
-
-
0028908269
-
Mirtazapine is more effective than trazodone: A controlled study in hospitalised patients with major depression
-
7. Van Moffaert M, De Wilde J, Vereecken A, et al. Mirtazapine is more effective than trazodone: a controlled study in hospitalised patients with major depression. Int Clin Psychopharmacol 1995; 10: 3-9
-
(1995)
Int Clin Psychopharmacol
, vol.10
, pp. 3-9
-
-
Van Moffaert, M.1
De Wilde, J.2
Vereecken, A.3
-
8
-
-
0031927915
-
Mirtazapine: Efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive disorder
-
Mirtazapine-Fluoxetine Study Group
-
8. Wheatley DP, Van Moffaert M, Timmerman L, et al. Mirtazapine: efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive disorder. Mirtazapine-Fluoxetine Study Group. J Clin Psychiatr 1998; 59: 306-12
-
(1998)
J Clin Psychiatr
, vol.59
, pp. 306-312
-
-
Wheatley, D.P.1
Van Moffaert, M.2
Timmerman, L.3
-
9
-
-
0013653971
-
Org 3770 vs amitriptyline: A 6-week randomised double-blind multicentre trial in hospitalised patients
-
9. Zivkov M, De Jongh G. Org 3770 vs amitriptyline: a 6-week randomised double-blind multicentre trial in hospitalised patients. Hum Psychopharmacol 1995; 10: 263-71
-
(1995)
Hum Psychopharmacol
, vol.10
, pp. 263-271
-
-
Zivkov, M.1
De Jongh, G.2
-
10
-
-
0029745693
-
A multicentre double-blind, amitriptyline-controlled study of mirtazapine in patients with major depression
-
10. Mullin J, Lodge A, Bennie E, et al. A multicentre double-blind, amitriptyline-controlled study of mirtazapine in patients with major depression. J Psychopharmacol 1996; 10: 235-40
-
(1996)
J Psychopharmacol
, vol.10
, pp. 235-240
-
-
Mullin, J.1
Lodge, A.2
Bennie, E.3
-
11
-
-
0029118693
-
A multicentre, double-blind, clomipramine-controlled efficacy and safety study of Org 3770
-
11. Richou H, Ruimy P, Charbaut J, et al. A multicentre, double-blind, clomipramine-controlled efficacy and safety study of Org 3770. Hum Psychopharmacol 1995; 10: 263-71
-
(1995)
Hum Psychopharmacol
, vol.10
, pp. 263-271
-
-
Richou, H.1
Ruimy, P.2
Charbaut, J.3
-
12
-
-
0028792322
-
A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression
-
12. Marttilla M, Jääskeläinen J, Järvi R, et al. A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression. Eur Neuropsychopharmacol 1995; 5: 441-6
-
(1995)
Eur Neuropsychopharmacol
, vol.5
, pp. 441-446
-
-
Marttilla, M.1
Jääskeläinen, J.2
Järvi, R.3
-
13
-
-
0000467740
-
Clinically relevant sizes in depression
-
13. Montgomery SA. Clinically relevant sizes in depression. Eur Neuropsychopharmacol 1994; 4: 283-4
-
(1994)
Eur Neuropsychopharmacol
, vol.4
, pp. 283-284
-
-
Montgomery, S.A.1
-
14
-
-
0032729491
-
Efficacy and tolerability of mirtazapine versus citalopram: A double-blind, randomized study in patients with major depressive disorder
-
14. Leinonen E, Skarstein J, Behnke K, et al. Efficacy and tolerability of mirtazapine versus citalopram: a double-blind, randomized study in patients with major depressive disorder. Int Clin Psychopharmacol 1999; 14: 329-37
-
(1999)
Int Clin Psychopharmacol
, vol.14
, pp. 329-337
-
-
Leinonen, E.1
Skarstein, J.2
Behnke, K.3
-
15
-
-
0032841611
-
Mirtazapine versus selective serotonin reuptake inhibitors
-
15. Thompson C. Mirtazapine versus selective serotonin reuptake inhibitors. J Clin Psychiatry 1999; 60 Suppl. 17: 18-22
-
(1999)
J Clin Psychiatry
, vol.60
, Issue.SUPPL. 17
, pp. 18-22
-
-
Thompson, C.1
-
16
-
-
0032863310
-
New developments in the treatment of depression
-
16. Montgomery SA. New developments in the treatment of depression. J Clin Psychiatry 1999; 60 Suppl. 14: 19-5
-
(1999)
J Clin Psychiatry
, vol.60
, Issue.SUPPL. 14
, pp. 19-25
-
-
Montgomery, S.A.1
-
18
-
-
0029150570
-
Org 3770 (mirtazapine) versus trazodone: A placebo controlled trial in depressed elderly patients
-
18. Halikas JA. Org 3770 (mirtazapine) versus trazodone: a placebo controlled trial in depressed elderly patients. Hum Psychopharmacol 1995; 10 Suppl. 2: S125-33
-
(1995)
Hum Psychopharmacol
, vol.10
, Issue.SUPPL. 2
-
-
Halikas, J.A.1
-
19
-
-
0029994575
-
A double blind multicentre comparison of mirtazapine and amitriptyline in elderly depressed patients
-
19. Hoeyberg OJ, Maragakis B, Mullin J, et al. A double blind multicentre comparison of mirtazapine and amitriptyline in elderly depressed patients. Acta Psychiatr Scand 1996; 93: 184-90
-
(1996)
Acta Psychiatr Scand
, vol.93
, pp. 184-190
-
-
Hoeyberg, O.J.1
Maragakis, B.2
Mullin, J.3
-
20
-
-
0030742298
-
Pharmacokinetics of mirtazapine from orally administered tablets: Influence of a high-fat meal
-
20. Cohen M, Panagides J, Timmer CJ, et al. Pharmacokinetics of mirtazapine from orally administered tablets: influence of a high-fat meal. Eur J Drug Metab Pharmacokinet 1997; 22: 103-10
-
(1997)
Eur J Drug Metab Pharmacokinet
, vol.22
, pp. 103-110
-
-
Cohen, M.1
Panagides, J.2
Timmer, C.J.3
-
21
-
-
85037967129
-
-
Oss: N.V. Organon. Data on file
-
21. Colbers EPH, Boom SPA, Kleijn HJ, et al. Single-dose, fasting, open, randomised, two-way cross-over bioequivalence study on Org 3770 oral liquid versus 15 mg tablet in thirty-two healthy volunteer subjects [Study 22523, Report No. NL 0012550]. Oss: N.V. Organon, 1999. (Data on file)
-
(1999)
Single-dose, Fasting, Open, Randomised, Two-way Cross-over Bioequivalence Study on Org 3770 Oral Liquid Versus 15 mg Tablet in Thirty-two Healthy Volunteer Subjects [Study 22523, Report No. NL 0012550]
-
-
Colbers, E.P.H.1
Boom, S.P.A.2
Kleijn, H.J.3
-
22
-
-
0029028790
-
Bioavailability of mirtazapine from Remeron® tablets after single and multiple oral dosing
-
22. Voortman G, Paanakker JE. Bioavailability of mirtazapine from Remeron® tablets after single and multiple oral dosing. Hum Psychopharmacol 1995; 10 Suppl.: S83-96
-
(1995)
Hum Psychopharmacol
, vol.10
, Issue.SUPPL.
-
-
Voortman, G.1
Paanakker, J.E.2
-
23
-
-
0031874360
-
Mirtazapine oral single dose kinetics in patients with different degrees of renal failure
-
23. Bengtsson F, Höglund P, Timmer C, et al. Mirtazapine oral single dose kinetics in patients with different degrees of renal failure. Hum Psychopharmacol 1998; 13: 357-65
-
(1998)
Hum Psychopharmacol
, vol.13
, pp. 357-365
-
-
Bengtsson, F.1
Höglund, P.2
Timmer, C.3
-
24
-
-
0027448196
-
Influence of hepatic impairment on the pharmacokinetics of single doses of mirtazapine in elderly subjects
-
24. Murdoch DL, Ashgar J, Ankier SI, et al. Influence of hepatic impairment on the pharmacokinetics of single doses of mirtazapine in elderly subjects [abstract]. Br J Clin Pharmacol 1993; 35: 76P
-
(1993)
Br J Clin Pharmacol
, vol.35
-
-
Murdoch, D.L.1
Ashgar, J.2
Ankier, S.I.3
-
25
-
-
0030460935
-
Pharmacokinetics of mirtazapine from orally administered tablets: Influence of gender, age and treatment regimen
-
25. Timmer CJ, Paanakker JE, Van Hal HJM. Pharmacokinetics of mirtazapine from orally administered tablets: influence of gender, age and treatment regimen. Hum Psychopharmacol 1996; 11: 497-509
-
(1996)
Hum Psychopharmacol
, vol.11
, pp. 497-509
-
-
Timmer, C.J.1
Paanakker, J.E.2
Van Hal, H.J.M.3
-
27
-
-
85037950547
-
-
Oss: N.V. Organon. Data on file
-
27. Timmer CJ, Paanakker JE, Mink CPA, et al. Assessment of the bioequivalence of four oral Org 3770 formulations (30mg tablet, 15mg tablet, 5mg tablet and 5mg capsule) in healthy, young, male subjects [Study 88003, Report No. 2499]. Oss: N.V. Organon, 1989. (Data on file)
-
(1989)
Assessment of the Bioequivalence of Four Oral Org 3770 Formulations (30mg Tablet, 15mg Tablet, 5mg Tablet and 5mg Capsule) in Healthy, Young, Male Subjects [Study 88003, Report No. 2499]
-
-
Timmer, C.J.1
Paanakker, J.E.2
Mink, C.P.A.3
-
29
-
-
85037953666
-
-
Oss: N.V. Organon. Data on file
-
29. Vrijmoed-De Vries MC, Kleijn HJ, Colbers EPH, et al. Single-dose, fasting, open, two-way cross-over bioequivalence trial on Org 3770 30 mg OraSolv® tablet versus 30 mg Org 3770 marketed tablet in 40 healthy subjects [Study 22527, Report No. NL 0016343]. Oss: N.V. Organon, 1999. (Data on file)
-
(1999)
Single-dose, Fasting, Open, Two-way Cross-over Bioequivalence Trial on Org 3770 30 mg OraSolv® Tablet Versus 30 mg Org 3770 Marketed Tablet in 40 Healthy Subjects [Study 22527, Report No. NL 0016343]
-
-
Vrijmoed-De Vries, M.C.1
Kleijn, H.J.2
Colbers, E.P.H.3
-
31
-
-
0029074770
-
Pharmacokinetic dose-proportionality study at steady state of mirtazapine from Remeron® tablets
-
31. Timmer CJ, Lohmann AAM, Mink CPA. Pharmacokinetic dose-proportionality study at steady state of mirtazapine from Remeron® tablets. Hum Psychopharmacol 1995; 10 Suppl.: S97-106
-
(1995)
Hum Psychopharmacol
, vol.10
, Issue.SUPPL.
-
-
Timmer, C.J.1
Lohmann, A.A.M.2
Mink, C.P.A.3
-
32
-
-
85037959624
-
-
Oss: N.V. Organon. Data on file
-
32. Peeters PAM, Brett MA, Van den Heuvel MW. A phase I, multiple dose, pharmacokinetic and safety comparison study of Org 3770 between healthy male Japanese and Caucasian volunteers (Study 22525]. Oss: N.V. Organon, 2000. (Data on file)
-
(2000)
A Phase I, Multiple Dose, Pharmacokinetic and Safety Comparison Study of Org 3770 between Healthy Male Japanese and Caucasian Volunteers (Study 22525]
-
-
Peeters, P.A.M.1
Brett, M.A.2
Van Den Heuvel, M.W.3
-
33
-
-
0031048167
-
Mirtazapine pharmacoktnetics with two dosage regimens and two pharmaceutical formulations
-
33. Timmer CJ, Paanakker JE, Vrijmoed-De Vries M. Mirtazapine pharmacoktnetics with two dosage regimens and two pharmaceutical formulations. Pharm Res 1997; 14: 98-102
-
(1997)
Pharm Res
, vol.14
, pp. 98-102
-
-
Timmer, C.J.1
Paanakker, J.E.2
Vrijmoed-De Vries, M.3
-
35
-
-
0003560781
-
-
Oss: N.V. Organon. Data on file
-
35. Ebes F, Van Lookeren-Campagne AM, Hartmans HLA, et al. A phase I, single center, single-blind, placebo-controlled multiple dose study of the interaction between Org 3770 and carbamazepine in healthy male volunteers [Study 22514, Report No. NL 0003854]. Oss: N.V. Organon, 1998. (Data on file)
-
(1998)
A Phase I, Single Center, Single-blind, Placebo-controlled Multiple Dose Study of the Interaction between Org 3770 and Carbamazepine in Healthy Male Volunteers [Study 22514, Report No. NL 0003854]
-
-
Ebes, F.1
Van Lookeren-Campagne, A.M.2
Hartmans, H.L.A.3
-
36
-
-
85037955339
-
Concomitant use of mirtazapine and cimetidine: A drug-drug interaction study in healthy male subjects
-
In press
-
36. Sitsen JMA, Maris FA, Timmer CJ. Concomitant use of mirtazapine and cimetidine: a drug-drug interaction study in healthy male subjects. Eur J Clin Pharmacol. In press
-
Eur J Clin Pharmacol.
-
-
Sitsen, J.M.A.1
Maris, F.A.2
Timmer, C.J.3
-
37
-
-
0003560780
-
-
Oss: N.V. Organon. Data on file
-
37. Van Lookeren-Campagne AM, Hartmans HLA, Ruwe FJL, et al. A phase I, single center, randomized, partially double-blind, multiple dose, three-way cross-over study of the pharmacokinetic and pharmacodynamic interaction of Org 3770 (mirtazapine) and paroxetine in healthy volunteers [Study 22511, Report No. NL 0010166]. Oss: N.V. Organon, 1998. (Data on file)
-
(1998)
A Phase I, Single Center, Randomized, Partially Double-blind, Multiple Dose, Three-way Cross-over Study of the Pharmacokinetic and Pharmacodynamic Interaction of Org 3770 (Mirtazapine) and Paroxetine in Healthy Volunteers [Study 22511, Report No. NL 0010166]
-
-
Van Lookeren-Campagne, A.M.1
Hartmans, H.L.A.2
Ruwe, F.J.L.3
-
38
-
-
0031930087
-
Pharmacokinetics and biotransformation of mirtazapine in human volunteers
-
38. Delbressine LPC, Moonen MEG, Kaspersen FM, et al. Pharmacokinetics and biotransformation of mirtazapine in human volunteers. Clin Drug Invest 1998; 15: 45-55
-
(1998)
Clin Drug Invest
, vol.15
, pp. 45-55
-
-
Delbressine, L.P.C.1
Moonen, M.E.G.2
Kaspersen, F.M.3
-
39
-
-
0025338183
-
Biointernational '89
-
39. Midha K. Biointernational '89. Int Pharm J 4 1990; 3: 101-3
-
(1990)
Int Pharm J 4
, vol.3
, pp. 101-103
-
-
Midha, K.1
-
42
-
-
0031029475
-
In vitro and in vivo studies on the disposition of mirtazapine in humans
-
42. Dahl ML, Voortman G, Alm C, et al. In vitro and in vivo studies on the disposition of mirtazapine in humans. Clin Drug Invest 1997; 13: 37-46
-
(1997)
Clin Drug Invest
, vol.13
, pp. 37-46
-
-
Dahl, M.L.1
Voortman, G.2
Alm, C.3
-
44
-
-
0025365963
-
Contributions of the enantiomers of mirtazapine (Org 3770) and its demethyl metabolite to its neuropharmacological profile in rats
-
44. De Graaf JS, Delbressine LPC. Contributions of the enantiomers of mirtazapine (Org 3770) and its demethyl metabolite to its neuropharmacological profile in rats. Eur J Pharmacol 1990; 183; 583-4
-
(1990)
Eur J Pharmacol
, vol.183
, pp. 583-584
-
-
De Graaf, J.S.1
Delbressine, L.P.C.2
-
45
-
-
85037970920
-
-
Oss: N.V. Organon. Data on file
-
45. Mink CPA, Timmer CJ. A single-centre, double-blind, placebo-controlled phase I study in healthy male volunteers to assess the safety, tolerance and pharmacokinetics of intravenously administered Org 3770 [Study 22505. Report No. 3309]. Oss: N.V. Organon, 1993. (Data on file)
-
(1993)
A Single-centre, Double-blind, Placebo-controlled Phase I Study in Healthy Male Volunteers to Assess the Safety, Tolerance and Pharmacokinetics of Intravenously Administered Org 3770 [Study 22505. Report No. 3309]
-
-
Mink, C.P.A.1
Timmer, C.J.2
-
46
-
-
0025690366
-
Single dose pharmacokinetics of fluphenazine after fluphenazine decanoate administration
-
46. Simpson GM, Yadalam KG, Levinson DF, et al. Single dose pharmacokinetics of fluphenazine after fluphenazine decanoate administration. J Clin Psychophamacol 1990; 10: 417-21
-
(1990)
J Clin Psychophamacol
, vol.10
, pp. 417-421
-
-
Simpson, G.M.1
Yadalam, K.G.2
Levinson, D.F.3
-
47
-
-
0024468418
-
Dose-related plasma levels of clozapine: Influence of smoking behavior, sex and age
-
47. Haring C, Meise U, Humpel C, et al. Dose-related plasma levels of clozapine: influence of smoking behavior, sex and age. Psychopharmacology 1989; 99 Suppl. J: S38-40
-
(1989)
Psychopharmacology
, vol.99
, Issue.SUPPL. J
-
-
Haring, C.1
Meise, U.2
Humpel, C.3
-
48
-
-
0025833549
-
Thiothixene pharmacokinetic interactions: A study of hepatic enzyme inducers, clearance inhibitors, and demographic variables
-
48. Ereshefsky L, Saklad SR, Watanabe MD, et al. Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables. J Clin Psychopharmacol 1991; 11: 296-301
-
(1991)
J Clin Psychopharmacol
, vol.11
, pp. 296-301
-
-
Ereshefsky, L.1
Saklad, S.R.2
Watanabe, M.D.3
-
50
-
-
0030792394
-
Selection of an antidepressant: Mirtazapine
-
50. Preskorn SH. Selection of an antidepressant: mirtazapine. J Clin Psychiatry 1997; 58 Suppl. 6: 3-8
-
(1997)
J Clin Psychiatry
, vol.58
, Issue.SUPPL. 6
, pp. 3-8
-
-
Preskorn, S.H.1
-
51
-
-
0032714390
-
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: A pilot study
-
51. Loonen, AJM, Doorschot CH, Oostelbos MCJM, et al. Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study. Eur Neuropsychopharmacol 1999; 10: 51-7
-
(1999)
Eur Neuropsychopharmacol
, vol.10
, pp. 51-57
-
-
Loonen, A.J.M.1
Doorschot, C.H.2
Oostelbos, M.C.J.M.3
-
52
-
-
4243338680
-
Immediate crossover from fluoxetine to mirtazapine
-
52. Preskorn SH, Omo K, Magnus R, et al. Immediate crossover from fluoxetine to mirtazapine. Biol Psychiatry 1997; 41: 96S
-
(1997)
Biol Psychiatry
, vol.41
-
-
Preskorn, S.H.1
Omo, K.2
Magnus, R.3
-
54
-
-
85037959465
-
-
Oss: N.V. Organon. Data on file
-
54. Manila M, Mattila MJ, Vrijmoed-de Vries M, et al. Actions and interactions of psychotropic drugs on human performance and mood: single doses of Org 3770, amitriptyline and diazepam [Study 85148, Report No. 2468]. Oss: N.V. Organon, 1989. (Data on file)
-
(1989)
Actions and Interactions of Psychotropic Drugs on Human Performance and Mood: Single Doses of Org 3770, Amitriptyline and Diazepam [Study 85148, Report No. 2468]
-
-
Manila, M.1
Mattila, M.J.2
Vrijmoed-De Vries, M.3
-
56
-
-
0029046487
-
The alpha-2-selective adrenoceptor antagonist Org 3770 (Mirtazapine, Remeron) enhances noradrenergic and serotonergic transmission
-
56. De Boer T, Ruigt GSF, Berendsen HHG. The alpha-2-selective adrenoceptor antagonist Org 3770 (Mirtazapine, Remeron) enhances noradrenergic and serotonergic transmission. Hum Psychopharmacol 1995; 10 Suppl.: S107-18
-
(1995)
Hum Psychopharmacol
, vol.10
, Issue.SUPPL.
-
-
De Boer, T.1
Ruigt, G.S.F.2
Berendsen, H.H.G.3
|