Biology-inspired synthesis of compound libraries

Cellular and Molecular Life Sciences

Volumn 65, Issue 7-8, 2008, Pages 1186-1201

  Kaiser, M ^a   Wetzel, S ^b,c   Kumar, K ^b,c   Waldmann, H ^b,c  

^a CHEMICAL GENOMICS CENTRE OF THE MAX PLANCK SOCIETY   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Biology oriented synthesis (BIOS); Chemical biology; Compound libraries; Diversity oriented synthesis (DOS)

Indexed keywords

BINDING AFFINITY; BINDING SITE; BIOCHEMISTRY; BIOLOGICAL ACTIVITY; BIOLOGY; BIOSYNTHESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; HIGH THROUGHPUT SCREENING; PHENOTYPE; QUALITATIVE ANALYSIS; REVIEW; SCREENING; STATISTICAL ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SYNTHESIS;

BINDING SITES; BIOLOGICAL PRODUCTS; CONSERVED SEQUENCE; SMALL MOLECULE LIBRARIES; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 42449139634     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-007-7492-1     Document Type: Review

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