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Angewandte Chemie - International Edition

Volumn 41, Issue 7, 2002, Pages 1174-1178

Natural product derived receptor tyrosine kinase inhibitors: Identification of IGF1R, Tie-2, and VEGFR-3 inhibitors

(5) Stahl, Petra a,b Kissau, Lars a,b Mazitschek, Ralph c Giannis, Athanassios c Waldmann, Herbert a,b

a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY (Germany)

b TU DORTMUND UNIVERSITY (Germany)

c UNIVERSITY OF KARLSRUHE (Germany)

Author keywords

Angiogenesis; Antitumor agents; Combinatorial chemistry; Natural products; Tyrosine kinases

Indexed keywords

BLOOD; ENZYME INHIBITION; TUMORS;

ANTITUMOR AGENTS;

ONCOLOGY;

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; DITERPENE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; QUINONE DERIVATIVE; RECEPTOR PROTEIN TYROSINE KINASES; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN RECEPTOR; TIE 2 RECEPTOR TYROSINE KINASE; TIE-2 RECEPTOR TYROSINE KINASE; VASCULOTROPIN RECEPTOR 3; ANGIOPOIETIN RECEPTOR;

AMINO ACID SEQUENCE; ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG USE; GENETICS; MOLECULAR GENETICS; NEOVASCULARIZATION (PATHOLOGY); SEQUENCE ALIGNMENT; TUMOR BLOOD FLOW; VASCULAR ENDOTHELIUM; DRUG ANTAGONISM; REVIEW;

AMINO ACID SEQUENCE; ANGIOGENESIS INHIBITORS; COMBINATORIAL CHEMISTRY TECHNIQUES; DITERPENES; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PATHOLOGIC; QUINONES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, IGF TYPE 1; SEQUENCE ALIGNMENT; SUPPORT, NON-U.S. GOV'T; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3; RECEPTOR, TIE-2;

EID: 0037006785 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/1521-3773(20020402)41:7<1174::AID-ANIE1174>3.0.CO;2-V Document Type: Article

Times cited : (92)

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