Protein structure similarity as guiding principle for combinatorial library design

Biological Chemistry

Volumn 384, Issue 9, 2003, Pages 1265-1272

  Koch, Marcus A ^a   Breinbauer, Rolf ^a   Waldmann, Herbert ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Bioinformatics; Chemical biology; Combination chemistry; Drug design; Inhibitors; Protein structure

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BESTATIN; CAPTOPRIL; CYCLIN DEPENDENT KINASE INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LEUKOTRIENE A4 HYDROLASE INHIBITOR; LIGAND; NAKIJIQUINONE DERIVATIVE; NUCLEOTIDE DERIVATIVE; OLOMOUCINE; PROTEIN KINASE INHIBITOR; QUINONE DERIVATIVE; SULFOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

COMBINATORIAL LIBRARY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; GENE IDENTIFICATION; HUMAN; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SEQUENCE ANALYSIS; SHORT SURVEY;

COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; EPOXIDE HYDROLASES; HUMANS; PROTEINS; STRUCTURAL HOMOLOGY, PROTEIN; SULFOTRANSFERASES;

EID: 0141828504     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2003.140     Document Type: Short Survey

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