A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

Molecular Cell

Volumn 11, Issue 4, 2003, Pages 1079-1092

  Downes, Michael ^a   Verdecia, Mark A ^b   Roecker, A J ^c   Hughes, Robert ^c   Hogenesch, John B ^d   Kast Woelbern, Heidi R ^e   Bowman, Marianne E ^b   Ferrer, Jean Luc ^f   Anisfeld, Andrew M ^e   Edwards, Peter A ^e   Rosenfeld, John M ^a   Alvarez, Jacqueline G A ^a   Noel, Joseph P ^b   Nicolaou, K C ^c,g   Evans, Ronald M ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; FARNESOID X RECEPTOR; FEXARAMINE; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL ANALYSIS; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFRACTION; GENE EXPRESSION PROFILING; GENE TARGETING; GENETIC ANALYSIS; GENOME ANALYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; LIVER CELL; NUCLEOTIDE SEQUENCE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

EID: 0037738531     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(03)00104-7     Document Type: Article

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