Solid-Phase Synthesis and Biological Evaluation of a Teleocidin Library - Discovery of a Selective PKCδ Down Regulator

Chemistry - A European Journal

Volumn 6, Issue 21, 2000, Pages 3943-3957

  Meseguer, Benjamín ^a   Alonso Díaz, Daniel ^a   Griebenow, Nils ^b   Herget, Thomas ^c   Waldmann, Herbert ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b BAYER AG   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Alkaloids; Combinatorial chemistry; Enzyme catalysis; Lactams; Protien kinase C; Signal transduction

Indexed keywords

ALKALOID; BRYOSTATIN 1; DEBROMOAPLYSIATOXIN; DIACYLGLYCEROL; INDOLACTAM V; ISOENZYME; LACTAM; LYNGBYATOXIN; MARCKS PROTEIN; MYRISTOYLATED ALANINE-RICH C KINASE SUBSTRATE; PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE C-DELTA; TELEOCIDIN; TRYPTOPHAN;

ANIMAL; ARTICLE; CATALYSIS; CELL CULTURE; CELL STRAIN 3T3; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; DOWN REGULATION; ENANTIOMER; ENZYME ACTIVATION; ENZYME INHIBITION; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SIGNAL TRANSDUCTION; STEREOISOMERISM; SYNTHESIS; THIN LAYER CHROMATOGRAPHY; WESTERN BLOTTING;

EID: 85046528002     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20001103)6:21<3943::AID-CHEM3943>3.3.CO;2-K     Document Type: Article

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