Molecular mechnisms of cellular senescence and immortalization of human cells

Expert Opinion on Therapeutic Targets

Volumn 11, Issue 12, 2007, Pages 1623-1637

  Kiyono, Tohru ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Ageing; Cyclin dependent kinase inhibitor; Eyelin dependent kinase; Immoralization; p16(INK4a); p21(WAF1 CIP1 SDI1); P38(MAPK); p53; Polycomb group; Reactive oxygen species; Retinoblastoma protein; Senescence; Senescence associated heterochromatic foci; Telomerase reverse transcriptase; Telomere

Indexed keywords

DNA METHYLTRANSFERASE; DOUBLE STRANDED DNA; GENE PRODUCT; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; PROTEIN P21; PROTEIN P53; PROTEIN SNF5; RAF PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN;

APOPTOSIS; CANCER INHIBITION; CELL AGING; CELL IMMORTALIZATION; CELL PROTECTION; DNA DAMAGE; DNA REPAIR; FIBROBLAST; GENE EXPRESSION REGULATION; GENE LOCUS; HETEROCHROMATIN; HUMAN; LIVER CARCINOMA; MELANOMA; NONHUMAN; ONCOGENE; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REVIEW; SARCOMA; TELOMERE; TRANSLATION INITIATION; ANIMAL; ARTICLE; CELL CYCLE; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL AGING; CELL CYCLE; CELL CYCLE PROTEINS; DNA DAMAGE; HUMANS; REACTIVE OXYGEN SPECIES; TELOMERE;

EID: 37349064784     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.11.12.1623     Document Type: Review

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