Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Nature Cell Biology

Volumn 4, Issue 1, 2002, Pages 11-20

  D’Orazi, Gabriella ^a,b   Cecchinelli, Barbara ^a   Bruno, Tiziana ^a   Manni, Isabella ^a   Higashimoto, Yuichiro ^c   Saito, Shin’ichi ^c   Gostissa, Monica ^d   Coen, Sabrina ^a   Marchetti, Alessandra ^a   Del Sal, Giannino ^d,e   Piaggio, Giulia ^a   Fanciulli, Maurizio ^a   Appella, Ettore ^c   Soddu, Silvia ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Inter University Consortium for Biotechnologies   (Italy)

^e Biophysics and Chemistry of Macromolecules   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; ISOPROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN 3; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; SERINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL NUCLEUS INCLUSION BODY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COOPERATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL NUCLEUS; ENZYME ACTIVATION; GENES, TUMOR SUPPRESSOR; HUMANS; MICE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; SERINE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; ULTRAVIOLET RAYS;

EID: 18244379872     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb714     Document Type: Article

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