Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

Nature

Volumn 413, Issue 6851, 2001, Pages 83-86

  Krimpenfort, Paul ^a   Quon, Kim C ^a   Mooi, Wolter J ^a   Loonstra, Ate ^a   Berns, Anton ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGENS; GENES; MUTAGENESIS; PROTEINS; TUMORS;

TUMORIGENESIS;

GENETIC ENGINEERING;

CYCLIN DEPENDENT KINASE INHIBITOR; DIMETHYLBENZ[A]ANTHRACENE; PROTEIN; PROTEIN P14 ARF; PROTEIN P16INK4A; UNCLASSIFIED DRUG; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; PROTEIN P14ARF;

MEDICINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; FIBROBLAST; GENE DISRUPTION; GENE LOCUS; GERM LINE; MALE; MELANOMA; METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; CELL CULTURE; CELL TRANSFORMATION; CYTOLOGY; EMBRYO; EXPERIMENTAL MELANOMA; GENE DELETION; GENETIC PREDISPOSITION; GENETICS; HUMAN; ONCOGENE RAS; PATHOLOGY; PHYSIOLOGY; POINT MUTATION;

ANIMALIA;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EMBRYO; FEMALE; FIBROBLASTS; GENE DELETION; GENES, P16; GENES, RAS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MELANOMA, EXPERIMENTAL; MICE; POINT MUTATION; PROTEINS; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 0035817687     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35092584     Document Type: Article

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