메뉴 건너뛰기




Volumn 21, Issue 13, 2002, Pages 3358-3369

Deconstructing PML-induced premature senescence

Author keywords

p53; PML; PML nuclear bodies; Senescence; Telomerase

Indexed keywords

LYSINE; PROTEIN P53; RAS PROTEIN; SERINE; TELOMERASE;

EID: 0036646102     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf341     Document Type: Article
Times cited : (190)

References (58)
  • 4
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1
  • 7
    • 18244379872 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
    • (2002) Nat. Cell Biol , vol.4 , pp. 11-19
    • D'Orazi, G.1
  • 11
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1
  • 12
    • 0035969103 scopus 로고    scopus 로고
    • DNA viruses and viral proteins that interact with PML nuclear bodies
    • (2001) Oncogene , vol.20 , pp. 7266-7273
    • Everett, R.D.1
  • 13
    • 7344248065 scopus 로고    scopus 로고
    • Cooperation between the RING + B1-B2 and coiled-coil domains of PML is necessary for its effects on cell survival
    • (1998) Oncogene , vol.16 , pp. 2905-2913
    • Fagioli, M.1
  • 15
    • 0034669124 scopus 로고    scopus 로고
    • Regulation of p53 activity in nuclear bodies by a specific PML isoform
    • (2000) EMBO J , vol.19 , pp. 6185-6195
    • Fogal, V.1
  • 19
    • 0032721540 scopus 로고    scopus 로고
    • PML is critical for ND10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1
    • (1999) J. Cell Biol , vol.147 , pp. 221-234
    • Ishov, A.M.1
  • 25
    • 0028293945 scopus 로고
    • The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion
    • (1994) EMBO J , vol.13 , pp. 1073-1083
    • Koken, M.H.1
  • 26
    • 0035908032 scopus 로고    scopus 로고
    • Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment and As203-induced PML or PML/retinoic acid receptor α degradation
    • (2001) J. Exp. Med , vol.193 , pp. 1361-1371
    • Lallemand-Breitenbach, V.1
  • 29
    • 0033583242 scopus 로고    scopus 로고
    • Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
    • (1999) J. Biol. Chem , vol.274 , pp. 7936-7940
    • Lee, A.C.1
  • 34
    • 0344299239 scopus 로고    scopus 로고
    • Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption
    • (1999) J. Virol , vol.73 , pp. 5137-5143
    • Muller, S.1    Dejean, A.2
  • 36
    • 0035969107 scopus 로고    scopus 로고
    • Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot
    • (2001) Oncogene , vol.20 , pp. 7234-7242
    • Negorev, D.1    Maul, G.G.2
  • 39
    • 0034644274 scopus 로고    scopus 로고
    • PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
    • (2000) Nature , vol.406 , pp. 207-210
    • Pearson, M.1
  • 40
    • 0035959740 scopus 로고    scopus 로고
    • High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth
    • (2001) Oncogene , vol.20 , pp. 6132-6141
    • Pierantoni, G.M.1
  • 48
    • 0029831907 scopus 로고    scopus 로고
    • Regulation of reactive-oxygen-species generation in fibroblasts by Racl
    • (1996) Biochem. J , vol.318 , pp. 379-382
    • Sundaresan, M.1
  • 49
    • 0037011958 scopus 로고    scopus 로고
    • p53 mutant mice that display early ageing-associated phenotypes
    • (2002) Nature , vol.415 , pp. 45-53
    • Tyner, S.D.1
  • 50
    • 0032567967 scopus 로고    scopus 로고
    • Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
    • (1998) Curr. Biol , vol.8 , pp. 279-282
    • Vaziri, H.1    Benchimol, S.2
  • 53
    • 0033119189 scopus 로고    scopus 로고
    • Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts
    • (1999) Cancer Res , vol.59 , pp. 1539-1543
    • Wei, S.1    Sedivy, J.M.2
  • 54
    • 0028158682 scopus 로고
    • Retinoic acid regulates aberrant nuclear localization of PML-RAR α in acute promyelocytic leukemia cells
    • (1994) Cell , vol.76 , pp. 345-356
    • Weis, K.1
  • 55
    • 0034730633 scopus 로고    scopus 로고
    • 2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres
    • (2000) J. Biol. Chem , vol.275 , pp. 30618-30622
    • Wu, G.1    Lee, W.H.2    Chen, P.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.