Virtual screening in drug discovery - A computational perspective

Current Protein and Peptide Science

Volumn 8, Issue 4, 2007, Pages 329-351

  Reddy, A Srinivas ^a   Pati, S Priyadarshini ^a   Kumar, P Praveen ^a   Pradeep, H N ^a   Sastry, G Narahari ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Binary descriptor; Consensus scoring; Monte carlo method; Structure based virtual screening; Support vector machine

Indexed keywords

ALDOSE REDUCTASE INHIBITOR; ASPARTIC PROTEINASE INHIBITOR; BLOOD CLOTTING FACTOR 10A INHIBITOR; CANNABOID RECEPTOR 1 INHIBITOR; CANNABOID RECEPTOR 2 INHIBITOR; CHECKPOINT KINASE 1 INHIBITOR; CHOLINESTERASE INHIBITOR; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DNA TOPOISOMERASE 2 ALPHA INHIBITOR; DOCKING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ESTROGEN RECEPTOR INHIBITOR; FALCIPAIN 2 INHIBITOR; FALCIPAIN 3 INHIBITOR; GROWTH HORMONE SECRETAGOGUE AGONIST; GYRASE INHIBITOR; HORMONE INHIBITOR; LEAD; MELANIN CONCENTRATING HORMONE 1 RECEPTOR INHIBITOR; METALLOPROTEINASE INHIBITOR; NEUROKININ 1 INHIBITOR; POTASSIUM CHANNEL KV1.5 INHIBITOR; PROTEIN INHIBITOR; PROTEIN KINASE INHIBITOR; SEROTONIN 2C RECEPTOR INHIBITOR; THYMIDINE MONOPHOSPHATE KINASE INHIBITOR; TRYPANOTHIONE REDUCTASE INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BIOINFORMATICS; COMPUTER PROGRAM; DRUG DESIGN; DRUG IDENTIFICATION; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; KNOWLEDGE BASE; MATHEMATICAL ANALYSIS; METHODOLOGY; PHARMACOPHORE; PROTEOMICS; REVIEW; STRENGTH;

ALGORITHMS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DRUG DESIGN; LIGANDS; MOLECULAR CONFORMATION; PROTEIN BINDING; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNOLOGY, PHARMACEUTICAL;

EID: 34548288600     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920307781369427     Document Type: Review

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