Pharmacophore identification, in silico screening, and virtual library design for inhibitors of the human factor Xa

Journal of Chemical Information and Modeling

Volumn 45, Issue 1, 2005, Pages 146-159

  Krovat, Eva M ^a   Frühwirth, Karin H ^a   Langer, Thierry ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CHELATION; COAGULATION; DATABASE SYSTEMS; ENZYME INHIBITION; HEALTH CARE; MOLECULAR STRUCTURE; PHARMACOKINETICS; SILICON COMPOUNDS;

HUMAN FACTOR; LIGANDS; MOLECULAR DATABASES; PHARMACOPHORE;

HUMAN ENGINEERING;

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; FACTUAL DATABASE; HUMAN; LIBRARY; STRUCTURE ACTIVITY RELATION;

ANTICOAGULANTS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; DATABASES, FACTUAL; DRUG DESIGN; FACTOR XA; HUMANS; LIBRARIES, DIGITAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 13844319727     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci049778k     Document Type: Article

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