Pharmacophore-based virtual screening: The discovery of novel methionyl-tRNA synthetase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 18, 2006, Pages 4898-4907

  Kim, Su Yeon ^a   Lee, Yeon Sook ^b   Kang, Taehee ^b   Kim, Sunghoon ^a   Lee, Jeewoo ^a  

^a Tumor Microenvironment Global Core Research Center   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Methionyl tRNA synthetase inhibitors; Virtual ligand screening

Indexed keywords

ENZYME INHIBITOR; LEAD; METHIONINE TRANSFER RNA LIGASE; METHIONINE TRANSFER RNA LIGASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DATA BASE; DRUG MARKETING; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; ESCHERICHIA COLI; IC 50; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PHARMACOPHORE; VANCOMYCIN RESISTANT ENTEROCOCCUS;

BINDING SITES; ENZYME INHIBITORS; ESCHERICHIA COLI; METHIONINE-TRNA LIGASE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 33746807698     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.06.057     Document Type: Article

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