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Angewandte Chemie - International Edition

Volumn 43, Issue 2, 2003, Pages 248-251

Ligand-Supported Homology Modeling of G-Protein-Coupled Receptor Sites: Models Sufficient for Successful Virtual Screening

(2) Evers, Andreas a Klebe, Gerhard a

a PHILIPPS UNIVERSITY MARBURG (Germany)

Author keywords

Computer chemistry; G proteins; Protein models; Receptors

Indexed keywords

COMPUTER SIMULATION; DRUG PRODUCTS; MOLECULAR STRUCTURE;

DRUG DESIGN;

PROTEINS;

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; ASN 1377642; G PROTEIN COUPLED RECEPTOR; NEUROKININ 1 RECEPTOR; TACHYKININ RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; COMPUTER ANALYSIS; COMPUTER MODEL; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SCREENING; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; GTP-BINDING PROTEINS; LIGANDS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; RECEPTORS, NEUROKININ-1; RHODOPSIN; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0347123444 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/anie.200352776 Document Type: Article

Times cited : (99)

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