Selecting optimally diverse compounds from structure databases: A validation study of two-dimensional and three-dimensional molecular descriptors

Journal of Medicinal Chemistry

Volumn 40, Issue 8, 1997, Pages 1219-1229

  Matter, Hans ^a,b  

^a Tripos GmbH   (Germany)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ARTICLE; CHEMICAL STRUCTURE; DATA BASE; DRUG ACTIVITY; DRUG DESIGN; DRUG MANUFACTURE; PHYSICAL CHEMISTRY; STEREOCHEMISTRY;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CHEMISTRY, PHYSICAL; DATABASES, FACTUAL; DRUG DESIGN; ENZYME INHIBITORS; FOLIC ACID ANTAGONISTS; GENE LIBRARY; MODELS, MOLECULAR; MOLECULAR WEIGHT; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 0030943408     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960352+     Document Type: Article

References (72)

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