Efficient method for high-throughput virtual screening based on flexible docking: Discovery of novel acetylcholinesterase inhibitors

Journal of Medicinal Chemistry

Volumn 47, Issue 20, 2004, Pages 4818-4828

  Mizutani, Miho Yamada ^a   Itai, Akiko ^a  

^a Inst of Medicinal Molecular Design   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE INHIBITOR; LIGAND;

ARTICLE; AUTOMATION; CALCULATION; COMMERCIAL PHENOMENA; CONFORMATION; DATA BASE; DRUG DETERMINATION; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; IC 50; MOLECULE; PARAMETER; TECHNIQUE; X RAY CRYSTALLOGRAPHY;

ACETYLCHOLINESTERASE; ALGORITHMS; ANIMALS; CHOLINESTERASE INHIBITORS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER-AIDED DESIGN; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; TORPEDO;

EID: 4544366514     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030605g     Document Type: Article

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