Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies

Journal of Medicinal Chemistry

Volumn 49, Issue 12, 2006, Pages 3485-3495

  Tsai, Keng Chang ^a,c   Chen, Shih Yuan ^a   Liang, Po Huang ^b   Lu, I Lin ^d   Mahindroo, Neeraj ^d   Hsieh, Hsing Pang ^d   Chao, Yu Sheng ^d   Liu, Lincoln ^a   Liu, Donald ^a   Lien, Wei ^a   Lin, Thy Hou ^a   Wu, Su Ying ^d  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^c GENOMICS RESEARCH CENTER   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR;

ARTICLE; COMPUTER PROGRAM; DATA BASE; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; PHARMACOPHORE; SARS CORONAVIRUS; STRUCTURE ACTIVITY RELATION; VIROGENESIS; VIRTUAL SCREENING;

BINDING SITES; CYSTEINE ENDOPEPTIDASES; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SARS VIRUS; VIRAL PROTEINS;

EID: 33745133367     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050852f     Document Type: Article

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