2D and 3D quantitative structure-activity relationship studies on a series of bis-pyridinium compounds as choline kinase inhibitors

QSAR and Combinatorial Science

Volumn 25, Issue 10, 2006, Pages 860-872

  Janardhan, S ^a   Srivani, P ^a   Sastry, G Narahari ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

2D QSAR; bis pyridinium derivatives; ChoK; CoMFA; CoMSIA

Indexed keywords

COMPUTATIONAL CHEMISTRY; ENZYMES; MOLECULAR GRAPHICS;

2D-QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; BIS-PYRIDINIA DERIVATIVE; CHOLINE KINASE; COMFA; COMSIA; KINASE INHIBITORS; PYRIDINIUM; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES; TWO-DIMENSIONAL;

HEURISTIC METHODS;

BISPYRIDINIUM DERIVATIVE; CHOLINE KINASE; CHOLINE KINASE INHIBITOR; ENZYME INHIBITOR; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; FISHER EXACT TEST; HUMAN; IC 50; MULTIPLE LINEAR REGRESSION ANALYSIS; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

EID: 33750330064     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200530199     Document Type: Article

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