-
1
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
Struhl, G., and Adachi, A. (2000) Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. Mol. Cell. 6, 625-636
-
(2000)
Mol. Cell
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
2
-
-
2942557122
-
γ-Secretase: Proteasome of the membrane?
-
Kopan, R., and Ilagan, M. X. (2004) γ-Secretase: proteasome of the membrane? Nat. Rev. Mol. Cell. Biol. 5, 499-504
-
(2004)
Nat. Rev. Mol. Cell. Biol
, vol.5
, pp. 499-504
-
-
Kopan, R.1
Ilagan, M.X.2
-
3
-
-
3142512452
-
Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration
-
Koo, E. H., and Kopan, R. (2004) Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration. Nat. Med. 10 Suppl., S26-S33
-
(2004)
Nat. Med
, vol.10
, Issue.SUPPL.
-
-
Koo, E.H.1
Kopan, R.2
-
4
-
-
0034785188
-
Presenilins and the intramembrane proteolysis of proteins: Facts and fiction
-
De Strooper, B., and Annaert, W. (2001) Presenilins and the intramembrane proteolysis of proteins: facts and fiction. Nat. Cell Biol. 3, E221-E225
-
(2001)
Nat. Cell Biol
, vol.3
-
-
De Strooper, B.1
Annaert, W.2
-
5
-
-
0036548070
-
γ-Secretase, Notch, Aβ and Alzheimer's disease: Where do the presenilins fit in?
-
Sisodia, S. S., and St. George-Hyslop, P. H. (2002) γ-Secretase, Notch, Aβ and Alzheimer's disease: where do the presenilins fit in? Nat. Rev. Neurosci. 3, 281-290
-
(2002)
Nat. Rev. Neurosci
, vol.3
, pp. 281-290
-
-
Sisodia, S.S.1
St. George-Hyslop, P.H.2
-
6
-
-
0036898485
-
Alzheimer disease γ-secretase: A complex story of GxGD-type presenilin proteases
-
Haass, C., and Steiner, H. (2002) Alzheimer disease γ-secretase: a complex story of GxGD-type presenilin proteases. Trends Cell Biol. 12, 556-562
-
(2002)
Trends Cell Biol
, vol.12
, pp. 556-562
-
-
Haass, C.1
Steiner, H.2
-
7
-
-
0036432244
-
The presenilins
-
Tandon, A., and Fraser, P. (2002) The presenilins. Genome Biol. 3, 3011-3019
-
(2002)
Genome Biol
, vol.3
, pp. 3011-3019
-
-
Tandon, A.1
Fraser, P.2
-
8
-
-
0030922421
-
Presenilins: Genes for life and death
-
Haass, C. (1997) Presenilins: genes for life and death. Neuron 18, 687-690
-
(1997)
Neuron
, vol.18
, pp. 687-690
-
-
Haass, C.1
-
9
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe, D. J. (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81, 741-766
-
(2001)
Physiol. Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
10
-
-
3242811966
-
Functional reconstitution of γ-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2
-
Periz, G., and Fortini, M. E. (2004) Functional reconstitution of γ-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2. J. Neurosci. Res. 77, 309-322
-
(2004)
J. Neurosci. Res
, vol.77
, pp. 309-322
-
-
Periz, G.1
Fortini, M.E.2
-
11
-
-
2942604376
-
The γ-secretase complex: Machinery for intramembrane proteolysis
-
Iwatsubo, T. (2004) The γ-secretase complex: machinery for intramembrane proteolysis. Curr. Opin. Neurobiol. 14, 379-383
-
(2004)
Curr. Opin. Neurobiol
, vol.14
, pp. 379-383
-
-
Iwatsubo, T.1
-
12
-
-
0037431082
-
Aph-1, Pen-2, and nicastrin with presenilin generate an active γ-secretase complex
-
De Strooper, B. (2003) Aph-1, Pen-2, and nicastrin with presenilin generate an active γ-secretase complex. Neuron 38, 9-12
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
13
-
-
0242361783
-
Identity and function of γ-secretase
-
Kimberly, W. T., and Wolfe, M. S. (2003) Identity and function of γ-secretase. J. Neurosci. Res. 74, 353-360
-
(2003)
J. Neurosci. Res
, vol.74
, pp. 353-360
-
-
Kimberly, W.T.1
Wolfe, M.S.2
-
14
-
-
0034727409
-
Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased Aβ42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans
-
Zhang, D. M., Levitan, D., Yu, G., Nishimura, M., Chen, F., Tandon, A., Kawarai, T., Arawaka, S., Supala, A., Song, Y. Q., et al. (2000) Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased Aβ42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans. NeuroReport 11, 3227-3230
-
(2000)
NeuroReport
, vol.11
, pp. 3227-3230
-
-
Zhang, D.M.1
Levitan, D.2
Yu, G.3
Nishimura, M.4
Chen, F.5
Tandon, A.6
Kawarai, T.7
Arawaka, S.8
Supala, A.9
Song, Y.Q.10
-
15
-
-
0033536072
-
Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations
-
Song, W., Nadeau, P., Yuan, M., Yang, X., Shen, J., and Yankner, B. A. (1999) Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. Proc. Natl. Acad. Sci. U. S. A. 96, 6959-6963
-
(1999)
Proc. Natl. Acad. Sci. U. S. A
, vol.96
, pp. 6959-6963
-
-
Song, W.1
Nadeau, P.2
Yuan, M.3
Yang, X.4
Shen, J.5
Yankner, B.A.6
-
16
-
-
0033588991
-
Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster
-
Ye, Y., and Fortini, M. E. (1999) Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster. J. Cell Biol. 146, 1351-1364
-
(1999)
J. Cell Biol
, vol.146
, pp. 1351-1364
-
-
Ye, Y.1
Fortini, M.E.2
-
17
-
-
4043052896
-
Identification of the role of presenilins beyond Alzheimer's disease
-
Thinakaran, G., and Parent, A. T. (2004) Identification of the role of presenilins beyond Alzheimer's disease. Pharmacol. Res. 50, 411-418
-
(2004)
Pharmacol. Res
, vol.50
, pp. 411-418
-
-
Thinakaran, G.1
Parent, A.T.2
-
18
-
-
0034858432
-
Presenilin mutations and calcium signaling defects in the nervous and immune systems
-
Mattson, M. P., Chan, S. L., and Camandola, S. (2001) Presenilin mutations and calcium signaling defects in the nervous and immune systems. Bioessays 23, 733-744
-
(2001)
Bioessays
, vol.23
, pp. 733-744
-
-
Mattson, M.P.1
Chan, S.L.2
Camandola, S.3
-
19
-
-
0035853828
-
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation
-
Schneider, I., Reverse, D., Dewachter, I., Ris, L., Caluwaerts, N., Kuiperi, C., Gilis, M., Geerts, H., Kretzschmar, H., Godaux, E., et al. (2001) Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J. Biol. Chem. 276, 11539-11544
-
(2001)
J. Biol. Chem
, vol.276
, pp. 11539-11544
-
-
Schneider, I.1
Reverse, D.2
Dewachter, I.3
Ris, L.4
Caluwaerts, N.5
Kuiperi, C.6
Gilis, M.7
Geerts, H.8
Kretzschmar, H.9
Godaux, E.10
-
20
-
-
0037462753
-
Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein
-
Herms, J., Schneider, I., Dewachter, I., Caluwaerts, N., Kretzschmar, H., and Van Leuven, F. (2003) Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein. J. Biol. Chem. 278, 2484-2489
-
(2003)
J. Biol. Chem
, vol.278
, pp. 2484-2489
-
-
Herms, J.1
Schneider, I.2
Dewachter, I.3
Caluwaerts, N.4
Kretzschmar, H.5
Van Leuven, F.6
-
21
-
-
0034657414
-
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice
-
Leissring, M. A., Akbari, Y., Fanger, C. M., Cahalan, M. D., Mattson, M. P., and LaFerla, F. M. (2000) Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J. Cell Biol. 149, 793-798
-
(2000)
J. Cell Biol
, vol.149
, pp. 793-798
-
-
Leissring, M.A.1
Akbari, Y.2
Fanger, C.M.3
Cahalan, M.D.4
Mattson, M.P.5
LaFerla, F.M.6
-
22
-
-
0033712477
-
Presenilin-mediated modulation of capacitative calcium entry
-
Yoo, A. S., Cheng, I., Chung, S., Grenfell, T. Z., Lee, H., Pack-Chung, E., Handler, M., Shen, J., Xia, W., Tesco, G., et al. (2000) Presenilin-mediated modulation of capacitative calcium entry. Neuron 27, 561-572
-
(2000)
Neuron
, vol.27
, pp. 561-572
-
-
Yoo, A.S.1
Cheng, I.2
Chung, S.3
Grenfell, T.Z.4
Lee, H.5
Pack-Chung, E.6
Handler, M.7
Shen, J.8
Xia, W.9
Tesco, G.10
-
23
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama, T., Imaizumi, K., Sato, N., Miyoshi, K., Kudo, T., Hitomi, J., Morihara, T., Yoneda, T., Gomi, F., Mori, Y., et al. (1999) Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat. Cell Biol. 1, 479-485
-
(1999)
Nat. Cell Biol
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
Morihara, T.7
Yoneda, T.8
Gomi, F.9
Mori, Y.10
-
24
-
-
4444298732
-
Induction of neuronal death by ER stress in Alzheimer's disease
-
Katayama, T., Imaizumi, K., Manabe, T., Hitomi, J., Kudo, T., and Tohyama, M. (2004) Induction of neuronal death by ER stress in Alzheimer's disease. J. Chem. Neuroanat. 28, 67-78
-
(2004)
J. Chem. Neuroanat
, vol.28
, pp. 67-78
-
-
Katayama, T.1
Imaizumi, K.2
Manabe, T.3
Hitomi, J.4
Kudo, T.5
Tohyama, M.6
-
25
-
-
0033671650
-
Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression
-
Sato, N., Urano, F., Yoon Leem, J., Kim, S. H., Li, M., Donoviel, D., Bernstein, A., Lee, A. S., Ron, D., Veselits, M. L., et al. (2000) Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nat. Cell Biol. 2, 863-870
-
(2000)
Nat. Cell Biol
, vol.2
, pp. 863-870
-
-
Sato, N.1
Urano, F.2
Yoon Leem, J.3
Kim, S.H.4
Li, M.5
Donoviel, D.6
Bernstein, A.7
Lee, A.S.8
Ron, D.9
Veselits, M.L.10
-
26
-
-
0031593685
-
Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression
-
Roperch, J. P., Alvaro, V., Prieur, S., Tuynder, M., Nemani, M., Lethrosne, F., Piouffre, L., Gendron, M. C., Israeli, D., Dausset, J., et al. (1998) Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression. Nat. Med. 4, 835-838
-
(1998)
Nat. Med
, vol.4
, pp. 835-838
-
-
Roperch, J.P.1
Alvaro, V.2
Prieur, S.3
Tuynder, M.4
Nemani, M.5
Lethrosne, F.6
Piouffre, L.7
Gendron, M.C.8
Israeli, D.9
Dausset, J.10
-
27
-
-
0032531793
-
Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis
-
Zhang, Z., Hartmann, H., Do, V. M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., van de Wetering, M., Clevers, H., Saftig, P., et al. (1998) Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 395, 698-702
-
(1998)
Nature
, vol.395
, pp. 698-702
-
-
Zhang, Z.1
Hartmann, H.2
Do, V.M.3
Abramowski, D.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Sommer, B.7
van de Wetering, M.8
Clevers, H.9
Saftig, P.10
-
28
-
-
0037102939
-
Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress
-
Terro, F., Czech, C., Esclaire, F., Elyaman, W., Yardin, C., Baclet, M. C., Touchet, N., Tremp, G., Pradier, L., and Hugon, J. (2002) Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress. J. Neurosci. Res. 69, 530-539
-
(2002)
J. Neurosci. Res
, vol.69
, pp. 530-539
-
-
Terro, F.1
Czech, C.2
Esclaire, F.3
Elyaman, W.4
Yardin, C.5
Baclet, M.C.6
Touchet, N.7
Tremp, G.8
Pradier, L.9
Hugon, J.10
-
29
-
-
0028204224
-
Calcium ionophore increases amyloid β peptide production by cultured cells
-
Querfurth, H. W., and Selkoe, D. J. (1994) Calcium ionophore increases amyloid β peptide production by cultured cells. Biochemistry 33, 4550-4561
-
(1994)
Biochemistry
, vol.33
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
30
-
-
0034882422
-
Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro
-
Nakajima, M., Miura, M., Aosaki, T., and Shirasawa, T. (2001) Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro. J. Neurochem. 78, 807-814
-
(2001)
J. Neurochem
, vol.78
, pp. 807-814
-
-
Nakajima, M.1
Miura, M.2
Aosaki, T.3
Shirasawa, T.4
-
31
-
-
0032692216
-
Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease
-
Cecchi, C., Latorraca, S., Sorbi, S., Iantomasi, T., Favilli, F., Vincenzini, M. T., and Liguri, G. (1999) Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease. Neurosci. Lett. 275, 152-154
-
(1999)
Neurosci. Lett
, vol.275
, pp. 152-154
-
-
Cecchi, C.1
Latorraca, S.2
Sorbi, S.3
Iantomasi, T.4
Favilli, F.5
Vincenzini, M.T.6
Liguri, G.7
-
32
-
-
0345055313
-
Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production
-
Keller, J. N., Guo, Q., Holtsberg, F. W., Bruce-Keller, A. J., and Mattson, M. P. (1998) Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production. J. Neurosci. 18, 4439-4450
-
(1998)
J. Neurosci
, vol.18
, pp. 4439-4450
-
-
Keller, J.N.1
Guo, Q.2
Holtsberg, F.W.3
Bruce-Keller, A.J.4
Mattson, M.P.5
-
33
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
Guo, Q., Fu, W., Sopher, B. L., Miller, M. W., Ware, C. B., Martin, G. M., and Mattson, M. P. (1999) Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat. Med. 5, 101-106
-
(1999)
Nat. Med
, vol.5
, pp. 101-106
-
-
Guo, Q.1
Fu, W.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
34
-
-
0042536471
-
Neuronal and glial calcium signaling in Alzheimer's disease
-
Mattson, M. P., and Chan, S. L. (2003) Neuronal and glial calcium signaling in Alzheimer's disease. Cell Calcium 34, 385-397
-
(2003)
Cell Calcium
, vol.34
, pp. 385-397
-
-
Mattson, M.P.1
Chan, S.L.2
-
35
-
-
0037451784
-
Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines
-
Gamliel, A., Teicher, C., Hartmann, T., Beyreuther, K., and Stein, R. (2003) Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines. Neuroscience 117, 19-28
-
(2003)
Neuroscience
, vol.117
, pp. 19-28
-
-
Gamliel, A.1
Teicher, C.2
Hartmann, T.3
Beyreuther, K.4
Stein, R.5
-
36
-
-
0035827090
-
Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1
-
De Sarno, P., Lesort, M., Bijur, G. N., Johnson, G. V., and Jope, R. S. (2001) Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1. Brain Res. 903, 226-230
-
(2001)
Brain Res
, vol.903
, pp. 226-230
-
-
De Sarno, P.1
Lesort, M.2
Bijur, G.N.3
Johnson, G.V.4
Jope, R.S.5
-
37
-
-
0034551780
-
Presenilin-1 P264L knock-in mutation: Differential effects on Aβ production, amyloid deposition, and neuronal vulnerability
-
Siman, R., Reaume, A. G., Savage, M. J., Trusko, S., Lin, Y. G., Scott, R. W., and Flood, D. G. (2000) Presenilin-1 P264L knock-in mutation: differential effects on Aβ production, amyloid deposition, and neuronal vulnerability. J. Neurosci. 20, 8717-8726
-
(2000)
J. Neurosci
, vol.20
, pp. 8717-8726
-
-
Siman, R.1
Reaume, A.G.2
Savage, M.J.3
Trusko, S.4
Lin, Y.G.5
Scott, R.W.6
Flood, D.G.7
-
38
-
-
0033568677
-
Inhibition of AMPA responses by mutated presenilin 1
-
Moerman, A. M., and Barger, S. W. (1999) Inhibition of AMPA responses by mutated presenilin 1. J. Neurosci. Res. 57, 962-967
-
(1999)
J. Neurosci. Res
, vol.57
, pp. 962-967
-
-
Moerman, A.M.1
Barger, S.W.2
-
39
-
-
0032779694
-
Signal transduction from the endoplasmic reticulum to the cell nucleus
-
Pahl, H. L. (1999) Signal transduction from the endoplasmic reticulum to the cell nucleus. Physiol. Rev. 79, 683-701
-
(1999)
Physiol. Rev
, vol.79
, pp. 683-701
-
-
Pahl, H.L.1
-
40
-
-
0034644111
-
ER stress response: Getting the UPR hand on misfolded proteins
-
Hampton, R. Y. (2000) ER stress response: getting the UPR hand on misfolded proteins. Curr. Biol. 10, R518-R521
-
(2000)
Curr. Biol
, vol.10
-
-
Hampton, R.Y.1
-
41
-
-
0033562966
-
Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
-
Kaufman, R. J. (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13, 1211-1233
-
(1999)
Genes Dev
, vol.13
, pp. 1211-1233
-
-
Kaufman, R.J.1
-
42
-
-
0035900779
-
Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations
-
Katayama, T., Imaizumi, K., Honda, A., Yoneda, T., Kudo, T., Takeda, M., Mori, K., Rozmahel, R., Fraser, P., George-Hyslop, P. S., and Tohyama, M. (2001) Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations. J. Biol. Chem. 276, 43446-43454
-
(2001)
J. Biol. Chem
, vol.276
, pp. 43446-43454
-
-
Katayama, T.1
Imaizumi, K.2
Honda, A.3
Yoneda, T.4
Kudo, T.5
Takeda, M.6
Mori, K.7
Rozmahel, R.8
Fraser, P.9
George-Hyslop, P.S.10
Tohyama, M.11
-
43
-
-
0035976923
-
Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: Effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation
-
Siman, R., Flood, D. G., Thinakaran, G., and Neumar, R. W. (2001) Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation. J. Biol. Chem. 276, 44736-44743
-
(2001)
J. Biol. Chem
, vol.276
, pp. 44736-44743
-
-
Siman, R.1
Flood, D.G.2
Thinakaran, G.3
Neumar, R.W.4
-
44
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe, D. J. (2002) Alzheimer's disease is a synaptic failure. Science 298, 789-791
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
45
-
-
0032440973
-
Characterization of Drosophila Presenilin and its colocalization with Notch during development
-
Ye, Y., and Fortini, M. E. (1998) Characterization of Drosophila Presenilin and its colocalization with Notch during development. Mech. Dev. 79, 199-211
-
(1998)
Mech. Dev
, vol.79
, pp. 199-211
-
-
Ye, Y.1
Fortini, M.E.2
-
46
-
-
0030889705
-
Isolation and characterization of Drosophila presenilin homolog
-
Hong, C. S., and Koo, E. H. (1997) Isolation and characterization of Drosophila presenilin homolog. NeuroReport 8, 665-668
-
(1997)
NeuroReport
, vol.8
, pp. 665-668
-
-
Hong, C.S.1
Koo, E.H.2
-
47
-
-
0030971393
-
Cloning and characterization of the Drosophila presenilin homologue
-
Boulianne, G. L., Livne-Bar, I., Humphreys, J. M., Liang, Y., Lin, C., Rogaev, E., and St George-Hyslop, P. (1997) Cloning and characterization of the Drosophila presenilin homologue. NeuroReport 8, 1025-1029
-
(1997)
NeuroReport
, vol.8
, pp. 1025-1029
-
-
Boulianne, G.L.1
Livne-Bar, I.2
Humphreys, J.M.3
Liang, Y.4
Lin, C.5
Rogaev, E.6
St George-Hyslop, P.7
-
48
-
-
0024643283
-
Complete separation of four potassium currents in Drosophila
-
Singh, S., and Wu, C. F. (1989) Complete separation of four potassium currents in Drosophila. Neuron 2, 1325-1329
-
(1989)
Neuron
, vol.2
, pp. 1325-1329
-
-
Singh, S.1
Wu, C.F.2
-
49
-
-
0029059781
-
Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles
-
Gielow, M. L., Gu, G. G., and Singh, S. (1995) Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles. J. Neurosci. 15, 6085-6093
-
(1995)
J. Neurosci
, vol.15
, pp. 6085-6093
-
-
Gielow, M.L.1
Gu, G.G.2
Singh, S.3
-
50
-
-
0032737082
-
Genetic characterization of cytological region 77A-D harboring the presenilin gene of Drosophila melanogaster
-
Lukinova, N. I., Roussakova, V. V., and Fortini, M. E. (1999) Genetic characterization of cytological region 77A-D harboring the presenilin gene of Drosophila melanogaster. Genetics 153, 1789-1797
-
(1999)
Genetics
, vol.153
, pp. 1789-1797
-
-
Lukinova, N.I.1
Roussakova, V.V.2
Fortini, M.E.3
-
51
-
-
0017089101
-
Properties of the larval neuromuscular junction in Drosophila melanogaster
-
Jan, L. Y., and Jan, Y. N. (1976) Properties of the larval neuromuscular junction in Drosophila melanogaster. J. Physiol. (London) 262, 189-214
-
(1976)
J. Physiol. (London)
, vol.262
, pp. 189-214
-
-
Jan, L.Y.1
Jan, Y.N.2
-
52
-
-
0022380606
-
Voltage clamp analysis of membrane currents in larval muscle fibers of Drosophila: Alteration of potassium currents in Shaker mutants
-
Wu, C. F., and Haugland, F. N. (1985) Voltage clamp analysis of membrane currents in larval muscle fibers of Drosophila: alteration of potassium currents in Shaker mutants. J. Neurosci. 5, 2626-2640
-
(1985)
J. Neurosci
, vol.5
, pp. 2626-2640
-
-
Wu, C.F.1
Haugland, F.N.2
-
53
-
-
0022119763
-
Classical conditioning and retention in normal and mutant Drosophila melanogaster
-
Tully, T., and Quinn, W. G. (1985) Classical conditioning and retention in normal and mutant Drosophila melanogaster. J. Comp. Physiol. [A] 157, 263-277
-
(1985)
J. Comp. Physiol
, vol.157
, Issue.A
, pp. 263-277
-
-
Tully, T.1
Quinn, W.G.2
-
54
-
-
0033535555
-
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants
-
Ye, Y., Lukinova, N., and Fortini, M. E. (1999) Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature 398, 525-529
-
(1999)
Nature
, vol.398
, pp. 525-529
-
-
Ye, Y.1
Lukinova, N.2
Fortini, M.E.3
-
55
-
-
0025752446
-
+ currents in Drosophila muscle and their pharmacological block
-
+ currents in Drosophila muscle and their pharmacological block. J. Membr. Biol. 121, 237-248
-
(1991)
J. Membr. Biol
, vol.121
, pp. 237-248
-
-
Gorczyca, M.G.1
Wu, C.F.2
-
56
-
-
0026688388
-
Heat shock response in Drosophila
-
Pauli, D., Arrigo, A. P., and Tissieres, A. (1992) Heat shock response in Drosophila. Experientia 48, 623-629
-
(1992)
Experientia
, vol.48
, pp. 623-629
-
-
Pauli, D.1
Arrigo, A.P.2
Tissieres, A.3
-
57
-
-
0029926999
-
The Drosophila neuromuscular junction: A model system for studying synaptic development and function
-
Keshishian, H., Broadie, K., Chiba, A., and Bate, M. (1996) The Drosophila neuromuscular junction: a model system for studying synaptic development and function. Annu. Rev. Neurosci. 19, 545-575
-
(1996)
Annu. Rev. Neurosci
, vol.19
, pp. 545-575
-
-
Keshishian, H.1
Broadie, K.2
Chiba, A.3
Bate, M.4
-
58
-
-
0014259321
-
The role of calcium in neuromuscular facilitation
-
Katz, B., and Miledi, R. (1968) The role of calcium in neuromuscular facilitation. J. Physiol. (London) 195, 481-492
-
(1968)
J. Physiol. (London)
, vol.195
, pp. 481-492
-
-
Katz, B.1
Miledi, R.2
-
59
-
-
0037431131
-
2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals
-
2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals. Neuron 38, 79-88
-
(2003)
Neuron
, vol.38
, pp. 79-88
-
-
Blatow, M.1
Caputi, A.2
Burnashev, N.3
Monyer, H.4
Rozov, A.5
-
60
-
-
17944376442
-
APP processing and synaptic plasticity in presenilin-1 conditional knockout mice
-
Yu, H., Saura, C. A., Choi, S. Y., Sun, L. D., Yang, X., Handler, M., Kawarabayashi, T., Younkin, L., Fedeles, B., Wilson, M. A., et al. (2001) APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron 31, 713-726
-
(2001)
Neuron
, vol.31
, pp. 713-726
-
-
Yu, H.1
Saura, C.A.2
Choi, S.Y.3
Sun, L.D.4
Yang, X.5
Handler, M.6
Kawarabayashi, T.7
Younkin, L.8
Fedeles, B.9
Wilson, M.A.10
-
61
-
-
11144354609
-
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
-
Saura, C. A., Choi, S. Y., Beglopoulos, V., Malkani, S., Zhang, D., Rao, B. S., Chattarji, S., Kelleher, R. J., 3rd, Kandel, E. R., Duff, K., et al. (2004) Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron 42, 23-36
-
(2004)
Neuron
, vol.42
, pp. 23-36
-
-
Saura, C.A.1
Choi, S.Y.2
Beglopoulos, V.3
Malkani, S.4
Zhang, D.5
Rao, B.S.6
Chattarji, S.7
Kelleher 3rd, R.J.8
Kandel, E.R.9
Duff, K.10
-
62
-
-
0031841168
-
Developmental regulation of T-, N- and L-type calcium currents in mouse embryonic sensory neurones
-
Desmadryl, G., Hilaire, C., Vigues, S., Diochot, S., and Valmier, J. (1998) Developmental regulation of T-, N- and L-type calcium currents in mouse embryonic sensory neurones. Eur. J. Neurosci. 10, 545-552
-
(1998)
Eur. J. Neurosci
, vol.10
, pp. 545-552
-
-
Desmadryl, G.1
Hilaire, C.2
Vigues, S.3
Diochot, S.4
Valmier, J.5
-
63
-
-
0031915451
-
Facilitation of L-type calcium current in thalamic neurons
-
Kammermeier, P. J., and Jones, S. W. (1998) Facilitation of L-type calcium current in thalamic neurons. J. Neurophysiol. 79, 410-417
-
(1998)
J. Neurophysiol
, vol.79
, pp. 410-417
-
-
Kammermeier, P.J.1
Jones, S.W.2
-
64
-
-
0029910646
-
Voltage-dependent facilitation of calcium channels in rat neostriatal neurons
-
Song, W. J., and Surmeier, D. J. (1996) Voltage-dependent facilitation of calcium channels in rat neostriatal neurons. J. Neurophysiol. 76, 2290-2306
-
(1996)
J. Neurophysiol
, vol.76
, pp. 2290-2306
-
-
Song, W.J.1
Surmeier, D.J.2
-
65
-
-
0029666457
-
2+ channel facilitation in cerebellar granule cells: Expression of facilitation during development in culture
-
2+ channel facilitation in cerebellar granule cells: expression of facilitation during development in culture. J. Neurosci. 16, 4890-4902
-
(1996)
J. Neurosci
, vol.16
, pp. 4890-4902
-
-
Parri, H.R.1
Lansman, J.B.2
-
67
-
-
1242319239
-
The impact of splice isoforms on voltage-gated calcium channel α1 subunits
-
Jurkat-Rott, K., and Lehmann-Horn, F. (2004) The impact of splice isoforms on voltage-gated calcium channel α1 subunits. J. Physiol. (London) 554, 609-619
-
(2004)
J. Physiol. (London)
, vol.554
, pp. 609-619
-
-
Jurkat-Rott, K.1
Lehmann-Horn, F.2
-
68
-
-
0030006652
-
Influence of L-type Ca channel α2/δ-subunit on ionic and gating current in transiently transfected HEK 293 cells
-
Bangalore, R., Mehrke, G., Gingrich, K., Hofmann, F., and Kass, R. S. (1996) Influence of L-type Ca channel α2/δ-subunit on ionic and gating current in transiently transfected HEK 293 cells. Am. J. Physiol. 270, H1521-1528
-
(1996)
Am. J. Physiol
, vol.270
-
-
Bangalore, R.1
Mehrke, G.2
Gingrich, K.3
Hofmann, F.4
Kass, R.S.5
-
70
-
-
0027506332
-
Functional diversity of L-type calcium channels in rat cerebellar neurons
-
Forti, L., and Pietrobon, D. (1993) Functional diversity of L-type calcium channels in rat cerebellar neurons. Neuron 10, 437-450
-
(1993)
Neuron
, vol.10
, pp. 437-450
-
-
Forti, L.1
Pietrobon, D.2
-
71
-
-
0028047011
-
Selective potentiation of a novel calcium channel in rat hippocampal neurones
-
Kavalali, E. T., and Plummer, M. R. (1994) Selective potentiation of a novel calcium channel in rat hippocampal neurones. J. Physiol. (London) 480, 475-484
-
(1994)
J. Physiol. (London)
, vol.480
, pp. 475-484
-
-
Kavalali, E.T.1
Plummer, M.R.2
-
72
-
-
33751261593
-
2+ channel isoforms for brain function
-
2+ channel isoforms for brain function. Biochem. Soc. Trans. 34, 903-909
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 903-909
-
-
Striessnig, J.1
Koschak, A.2
Sinnegger-Brauns, M.J.3
Hetzenauer, A.4
Nguyen, N.K.5
Busquet, P.6
Pelster, G.7
Singewald, N.8
-
73
-
-
0026561420
-
Calcium channel β subunit heterogeneity: Functional expression of cloned cDNA from heart, aorta and brain
-
Hullin, R., Singer-Lahat, D., Freichel, M., Biel, M., Dascal, N., Hofmann, F., and Flockerzi, V. (1992) Calcium channel β subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. EMBO J. 11, 885-890
-
(1992)
EMBO J
, vol.11
, pp. 885-890
-
-
Hullin, R.1
Singer-Lahat, D.2
Freichel, M.3
Biel, M.4
Dascal, N.5
Hofmann, F.6
Flockerzi, V.7
-
75
-
-
0031017176
-
2+ channel by anchored cAMP-dependent protein kinase
-
2+ channel by anchored cAMP-dependent protein kinase. J. Neurosci. 17, 1243-1255
-
(1997)
J. Neurosci
, vol.17
, pp. 1243-1255
-
-
Johnson, B.D.1
Brousal, J.P.2
Peterson, B.Z.3
Gallombardo, P.A.4
Hockerman, G.H.5
Lai, Y.6
Scheuer, T.7
Catterall, W.A.8
-
76
-
-
0026674610
-
2+ channels in polarized planar bilayers. 3. Effects of phosphorylation by protein kinase C
-
2+ channels in polarized planar bilayers. 3. Effects of phosphorylation by protein kinase C. Biophys. J. 63, 639-647
-
(1992)
Biophys. J
, vol.63
, pp. 639-647
-
-
Ma, J.1
Gutierrez, L.2
Hosey, M.3
Rios, E.4
-
77
-
-
0028877710
-
Voltage-dependent potentiation of neuronal L-type calcium channels due to state-dependent phosphorylation
-
Sculptoreanu, A., Figourov, A., and De Groat, W. C. (1995) Voltage-dependent potentiation of neuronal L-type calcium channels due to state-dependent phosphorylation. Am. J. Physiol. 269, C725-C732
-
(1995)
Am. J. Physiol
, vol.269
-
-
Sculptoreanu, A.1
Figourov, A.2
De Groat, W.C.3
-
78
-
-
0033564438
-
Modulation of dihydropyridine-sensitive calcium channels in Drosophila by a cAMP-mediated pathway
-
Bhattacharya, A., Gu, G. G., and Singh, S. (1999) Modulation of dihydropyridine-sensitive calcium channels in Drosophila by a cAMP-mediated pathway. J. Neurobiol. 39, 491-500
-
(1999)
J. Neurobiol
, vol.39
, pp. 491-500
-
-
Bhattacharya, A.1
Gu, G.G.2
Singh, S.3
-
79
-
-
0030872199
-
Modulation of the dihydropyridine- sensitive calcium channels in Drosophila by a phospholipase C-mediated pathway
-
Gu, G. G., and Singh, S. (1997) Modulation of the dihydropyridine- sensitive calcium channels in Drosophila by a phospholipase C-mediated pathway. J. Neurobiol. 33, 265-275
-
(1997)
J. Neurobiol
, vol.33
, pp. 265-275
-
-
Gu, G.G.1
Singh, S.2
-
81
-
-
33748140720
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 126, 981-993
-
(2006)
Cell
, vol.126
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.-F.5
Hao, Y.-H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
82
-
-
15844425969
-
Endoproteolysis of Presenilin 1 and accumulation of processed derivatives in vivo
-
Thinakaran, G., Borchelt, D. R., Lee, M. K., Slunt, H. H., Spitzer, L., Kim, G., Ratovitsky, T., Davenport, F., Nordstedt, C., Seeger, M., et al. (1996) Endoproteolysis of Presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17, 181-190
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
-
83
-
-
0031931185
-
2+ current in fish cardiac myocytes: Effects of thermal acclimation and β-adrenergic stimulation
-
2+ current in fish cardiac myocytes: effects of thermal acclimation and β-adrenergic stimulation. J. Exp. Biol. 201, 533-547
-
(1998)
J. Exp. Biol
, vol.201
, pp. 533-547
-
-
Vornanen, M.1
-
86
-
-
0036457088
-
Glucocorticoids alter calcium conductances and calcium channel subunit expression in basolateral amygdala neurons
-
Karst, H., Nair, S., Velzing, E., Rumpff-van Essen, L., Slagter, E., Shinnick-Gallagher, P., and Joels, M. (2002) Glucocorticoids alter calcium conductances and calcium channel subunit expression in basolateral amygdala neurons. Eur. J. Neurosci. 16, 1083-1089
-
(2002)
Eur. J. Neurosci
, vol.16
, pp. 1083-1089
-
-
Karst, H.1
Nair, S.2
Velzing, E.3
Rumpff-van Essen, L.4
Slagter, E.5
Shinnick-Gallagher, P.6
Joels, M.7
-
87
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl, G., and Greenwald, I. (1999) Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398, 522-525
-
(1999)
Nature
, vol.398
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
88
-
-
0035816661
-
A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao, X., and Sudhof, T. C. (2001) A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293, 115-120
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
89
-
-
2642582435
-
Dissection of amyloid-β precursor protein-dependent transcriptional transactivation
-
Cao, X., and Sudhof, T. C. (2004) Dissection of amyloid-β precursor protein-dependent transcriptional transactivation. J. Biol. Chem. 279, 24601-24611
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24601-24611
-
-
Cao, X.1
Sudhof, T.C.2
-
90
-
-
20444398562
-
Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and APLP
-
Pardossi-Piquard, R., Petit, A., Kawarai, T., Sunyach, C., Alves da Costa, C., Vincent, B., Ring, S., D'Adamio, L., Shen, J., and Muller, U. (2005) Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and APLP. Neuron 46, 541-554
-
(2005)
Neuron
, vol.46
, pp. 541-554
-
-
Pardossi-Piquard, R.1
Petit, A.2
Kawarai, T.3
Sunyach, C.4
Alves da Costa, C.5
Vincent, B.6
Ring, S.7
D'Adamio, L.8
Shen, J.9
Muller, U.10
-
91
-
-
0038322593
-
γ-Secretase cleavage and binding to Fe65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins
-
Walsh, D. M., Fadeeva, J. V., LaVoie, M. J., Paliga, K., Eggert, S., Kimberly, W. T., Wasco, W., and Selkoe, D. J. (2003) γ-Secretase cleavage and binding to Fe65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry 42, 6664-6673
-
(2003)
Biochemistry
, vol.42
, pp. 6664-6673
-
-
Walsh, D.M.1
Fadeeva, J.V.2
LaVoie, M.J.3
Paliga, K.4
Eggert, S.5
Kimberly, W.T.6
Wasco, W.7
Selkoe, D.J.8
-
92
-
-
0034237814
-
Facilitation, augmentation and potentiation at central synapses
-
Thomson, A. M. (2000) Facilitation, augmentation and potentiation at central synapses. Trends Neurosci. 23, 305-312
-
(2000)
Trends Neurosci
, vol.23
, pp. 305-312
-
-
Thomson, A.M.1
-
93
-
-
0028179515
-
2+ channel is involved in the regulation of spontaneous transmitter release at developing neuromuscular synapses
-
2+ channel is involved in the regulation of spontaneous transmitter release at developing neuromuscular synapses. Neuroscience 58, 131-140
-
(1994)
Neuroscience
, vol.58
, pp. 131-140
-
-
Fu, W.M.1
Huang, F.L.2
-
94
-
-
28044445059
-
Presynaptic modulation of synaptic transmission by pregnenolone sulfate as studied by optical recordings
-
Chen, L., and Sokabe, M. (2005) Presynaptic modulation of synaptic transmission by pregnenolone sulfate as studied by optical recordings. J. Neurophysiol. 94, 4131-4144
-
(2005)
J. Neurophysiol
, vol.94
, pp. 4131-4144
-
-
Chen, L.1
Sokabe, M.2
-
95
-
-
33645853170
-
Frequency-dependent depression of exocytosis and the role of voltage-gated calcium channels
-
Pamidimukkala, J., Habibi, S., and Hay, M. (2006) Frequency-dependent depression of exocytosis and the role of voltage-gated calcium channels. Brain Res. 1078, 1-8
-
(2006)
Brain Res
, vol.1078
, pp. 1-8
-
-
Pamidimukkala, J.1
Habibi, S.2
Hay, M.3
-
97
-
-
30744434111
-
V1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse
-
V1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse. J. Neurosci. 25, 11577-11585
-
(2005)
J. Neurosci
, vol.25
, pp. 11577-11585
-
-
Brandt, A.1
Khimich, D.2
Moser, T.3
-
98
-
-
0036095987
-
+-loaded terminals of rat hippocampal neurons
-
+-loaded terminals of rat hippocampal neurons. J. Neurophysiol. 87, 1222-1233
-
(2002)
J. Neurophysiol
, vol.87
, pp. 1222-1233
-
-
Lu, F.-M.1
Kuba, K.2
-
99
-
-
0028965467
-
Heterogeneous functional expression of calcium channels at sensory and synaptic regions in nodose neurons
-
Mendelowitz, D., Reynolds, P. J., and Andresen, M. C. (1995) Heterogeneous functional expression of calcium channels at sensory and synaptic regions in nodose neurons. J. Neurophysiol. 73, 872-875
-
(1995)
J. Neurophysiol
, vol.73
, pp. 872-875
-
-
Mendelowitz, D.1
Reynolds, P.J.2
Andresen, M.C.3
-
100
-
-
27344432023
-
2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory
-
2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory. J. Neurosci. 25, 9883-9892
-
(2005)
J. Neurosci
, vol.25
, pp. 9883-9892
-
-
Moosmang, S.1
Haider, N.2
Klugbauer, N.3
Adelsberger, H.4
Langwieser, N.5
Muller, J.6
Stiess, M.7
Marais, E.8
Schulla, V.9
Lacinova, L.10
-
102
-
-
0032506013
-
Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype
-
Fossgreen, A., Bruckner, B., Czech, C., Masters, C. L., Beyreuther, K., and Paro, R. (1998) Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype. Proc. Natl. Acad. Sci. U. S. A. 95, 13703-13708
-
(1998)
Proc. Natl. Acad. Sci. U. S. A
, vol.95
, pp. 13703-13708
-
-
Fossgreen, A.1
Bruckner, B.2
Czech, C.3
Masters, C.L.4
Beyreuther, K.5
Paro, R.6
-
103
-
-
0037129745
-
-
Lleo, A., Blesa, R., Gendre, J., Castellvi, M., Molinuevo, J. L., and Oliva, R. (2002) Clinical characteristics of a family with early-onset Alzheimer's disease associated with a presenilin 1 mutation (M139T). Med. Clin. (Barcelona) 118, 698-700
-
Lleo, A., Blesa, R., Gendre, J., Castellvi, M., Molinuevo, J. L., and Oliva, R. (2002) Clinical characteristics of a family with early-onset Alzheimer's disease associated with a presenilin 1 mutation (M139T). Med. Clin. (Barcelona) 118, 698-700
-
-
-
-
104
-
-
1342344129
-
Clinical, pathological, and biochemical spectrum of Alzheimer disease associated with PS-1 mutations
-
Lleo, A., Berezovska, O., Growdon, J. H., and Hyman, B. T. (2004) Clinical, pathological, and biochemical spectrum of Alzheimer disease associated with PS-1 mutations. Am. J. Geriatr. Psychiatry 12, 146-156
-
(2004)
Am. J. Geriatr. Psychiatry
, vol.12
, pp. 146-156
-
-
Lleo, A.1
Berezovska, O.2
Growdon, J.H.3
Hyman, B.T.4
-
105
-
-
85136419889
-
-
Lopera, F., Ardilla, A., Martinez, A., Madrigal, L., Arango-Viana, J. C., Lemere, C. A., Arango-Lasprilla, J. C., Hincapie, L., Arcos-Burgos, M., Ossa, J. E., et al. (1997) Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation. J. Am. Med. Assoc. 277, 793-799
-
Lopera, F., Ardilla, A., Martinez, A., Madrigal, L., Arango-Viana, J. C., Lemere, C. A., Arango-Lasprilla, J. C., Hincapie, L., Arcos-Burgos, M., Ossa, J. E., et al. (1997) Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation. J. Am. Med. Assoc. 277, 793-799
-
-
-
-
106
-
-
0442324932
-
Nongenetic factors as modifiers of the age of onset of familial Alzheimer's disease
-
Mejia, S., Giraldo, M., Pineda, D., Ardila, A., and Lopera, F. (2003) Nongenetic factors as modifiers of the age of onset of familial Alzheimer's disease. Int. Psychogeriatr. 15, 337-349
-
(2003)
Int. Psychogeriatr
, vol.15
, pp. 337-349
-
-
Mejia, S.1
Giraldo, M.2
Pineda, D.3
Ardila, A.4
Lopera, F.5
|