Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and APLP

Neuron

Volumn 46, Issue 4, 2005, Pages 541-554

  Pardossi Piquard, Raphaëlle ^a   Petit, Agnès ^a   Kawarai, Toshitaka ^b   Sunyach, Claire ^a   Da Costa, Cristine Alves ^a   Vincent, Bruno ^a   Ring, Sabine ^c   D'Adamio, Luciano ^d,e   Shen, Jie ^f   Müller, Ulrike ^c   Hyslop, Peter St George ^b   Checler, Frédéric ^a  

^a CNRS   (France)

^b TORONTO WESTERN HOSPITAL   (Canada)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE INHIBITOR; ISOPROTEIN; MEMBRANE METALLOENDOPEPTIDASE; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; PRESENILIN 1; PRESENILIN 2; UVOMORULIN;

ADULT; AGED; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

AGED; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; CADHERINS; CELLS, CULTURED; CLONING, MOLECULAR; DRUG INTERACTIONS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SPACE; FEMALE; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MEMBRANE PROTEINS; MICE; MIDDLE AGED; MODELS, BIOLOGICAL; MUTAGENESIS; NEPRILYSIN; PEPTIDE FRAGMENTS; PROMOTER REGIONS (GENETICS); PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; RECOMBINANT PROTEINS; TIME FACTORS; TRANSFECTION;

EID: 20444398562     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2005.04.008     Document Type: Article

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