Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro

Journal of Neurochemistry

Volumn 78, Issue 4, 2001, Pages 807-814

  Nakajima, Mitsunari ^a   Miura, Masami ^a   Aosaki, Toshihiko ^a   Shirasawa, Takuji ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Alzheimer's disease; BAPTA AM; Glutamate; Hydrogen peroxide; Neuronal death; Nifedipine

Indexed keywords

ANTIOXIDANT; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHELATING AGENT; DANTROLENE; GLUTAMIC ACID; HYDROGEN PEROXIDE; NIFEDIPINE; OMEGA CONOTOXIN; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL;

ALZHEIMER DISEASE; ANIMALS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CHELATING AGENTS; EGTAZIC ACID; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; NEURONS; OXIDATIVE STRESS; PEROXIDES; PRESENILIN-1;

EID: 0034882422     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00478.x     Document Type: Article

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