Disturbed Activation of Endoplasmic Reticulum Stress Transducers by Familial Alzheimer's Disease-linked Presenilin-1 Mutations

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 43446-43454

  Katayama, Taiichi ^a,f   Imaizumi, Kazunori ^b   Honda, Akiko ^a,c,f   Yoneda, Takunari ^a,f   Kudo, Takashi ^a   Takeda, Masatoshi ^a   Mori, Kazutoshi ^d   Rozmahel, Richard ^e   Fraser, Paul ^e   St George Hyslop, Peter ^e   Tohyama, Masaya ^a,f  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e UNIVERSITY OF TORONTO   (Canada)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; ENZYME INHIBITION; PROTEINS;

MUTANTS;

BIOCHEMISTRY;

ACTIVATING TRANSCRIPTION FACTOR 6; MEMBRANE PROTEIN; PHOSPHOTRANSFERASE; PKR LIKE ER KINASE; PRESENILIN 1; PROTEIN IRE1ALPHA; UNCLASSIFIED DRUG; ASPARTIC ACID; PSEN1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ARTICLE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRESS; UNFOLDED PROTEIN RESPONSE; ANIMAL; CELL CULTURE; CHEMISTRY; DOMINANT GENE; DOWN REGULATION; FIBROBLAST; FLUORESCENCE MICROSCOPY; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; PLASMID; PROTEIN BINDING; PROTEIN FOLDING; TIME; WESTERN BLOTTING;

ALZHEIMER DISEASE; ANIMALS; ASPARTIC ACID; BLOTTING, WESTERN; DOWN-REGULATION; ENDOPLASMIC RETICULUM; FIBROBLASTS; GENES, DOMINANT; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MUTATION; PLASMIDS; PRESENILIN-1; PROTEIN BINDING; PROTEIN FOLDING; SIGNAL TRANSDUCTION; STRESS; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035900779     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104096200     Document Type: Article

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