Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production

Journal of Neuroscience

Volumn 18, Issue 12, 1998, Pages 4439-4450

  Keller, Jeffrey N ^a,b   Quo, Qing ^b   Holtsberg, F W ^a   Bruce Keller, A J ^b   Mattson, Mark P ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

3 Nitropropionic acid; Alzheimer's disease; Amyloid; Caspase; Dantrolene; Glutathione; Malonate; Membrane permeability transition; Nifedipine; Peroxynitrite

Indexed keywords

3 NITROPROPIONIC ACID; ADENOSINE TRIPHOSPHATE; AMYLOID; ANTIOXIDANT; CALCIUM; DANTROLENE; MALONIC ACID; NIFEDIPINE; PEROXYNITRITE; PRESENILIN 1; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CELL LINE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; NERVE CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0345055313     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-12-04439.1998     Document Type: Article

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