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Volumn 23, Issue 3-4, 2006, Pages 125-163

CYP3A4 and MDR mediated interactions in drug therapy

Author keywords

Absorption; CYP3A4; Drug drug Interactions; Drug herbal Interactions; Metabolism; P gp; Pls and Recreational Drugs; Therapeutic Agents

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ALDOSTERONE; AMITRIPTYLINE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; ANTIRETROVIRUS AGENT; ATAZANAVIR; ATORVASTATIN; CARDIOVASCULAR AGENT; CELIPROLOL; CIMETIDINE; CISPLATIN; CYTOCHROME P450 3A4; DACTINOMYCIN; DEXAMETHASONE; DOXORUBICIN; ENFUVIRTIDE; GLYCOPROTEIN P; HERBACEOUS AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMATINIB; INDINAVIR; LOPINAVIR PLUS RITONAVIR; METHADONE; PACLITAXEL; QUINOLONE DERIVATIVE; RECREATIONAL DRUG; RITONAVIR; SAQUINAVIR; UNINDEXED DRUG; VALSPODAR; VINBLASTINE; VINCRISTINE; ZIDOVUDINE;

EID: 33847166853     PISSN: 10601333     EISSN: 15322521     Source Type: Journal    
DOI: 10.1080/10601330600961935     Document Type: Review
Times cited : (11)

References (253)
  • 1
    • 33644891064 scopus 로고    scopus 로고
    • MDR- and CYP3A4-mediated drug-herbal interactions
    • Pal D, Mitra AK. MDR- and CYP3A4-mediated drug-herbal interactions. Life Sci 2006; 78: 2131-2145.
    • (2006) Life Sci , vol.78 , pp. 2131-2145
    • Pal, D.1    Mitra, A.K.2
  • 2
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst P, Evers R, Kool M, Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst 2000; 92:1295-302.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 3
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993; 62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 5
    • 0007544439 scopus 로고    scopus 로고
    • MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
    • van Helvoort A, Smith AJ, Sprong H, Fritzsche I, Schinkel AH, Borst P, van Meer G.MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell 1996; 87:507-17.
    • (1996) Cell , vol.87 , pp. 507-517
    • van Helvoort, A.1    Smith, A.J.2    Sprong, H.3    Fritzsche, I.4    Schinkel, A.H.5    Borst, P.6    van Meer, G.7
  • 6
    • 0028307550 scopus 로고    scopus 로고
    • Ruetz S, Gros P. Phosphatidycholine translocase: a physiological role for the mdr2 gene. Cell 1994; 77:1071-1081.
    • Ruetz S, Gros P. Phosphatidycholine translocase: a physiological role for the mdr2 gene. Cell 1994; 77:1071-1081.
  • 7
    • 0034604707 scopus 로고    scopus 로고
    • MDR3 P-glycoprotein, phosphatidycholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with neucleotide trapping
    • Smith AJ, van Helvoort A, van Meer G, Szabo K, Welker E, Szakacs G, Varadi A, Sarkadi B, Borst P. MDR3 P-glycoprotein, phosphatidycholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with neucleotide trapping. J Biol Chem 2000; 275:23530-23539.
    • (2000) J Biol Chem , vol.275 , pp. 23530-23539
    • Smith, A.J.1    van Helvoort, A.2    van Meer, G.3    Szabo, K.4    Welker, E.5    Szakacs, G.6    Varadi, A.7    Sarkadi, B.8    Borst, P.9
  • 8
    • 0035813012 scopus 로고    scopus 로고
    • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters
    • Leslie EM, Deeley RG, Cole SP. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters, Toxicology 2001; 167:3-23.
    • (2001) Toxicology , vol.167 , pp. 3-23
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 10
    • 0027249710 scopus 로고    scopus 로고
    • Krishnamachary N, Center MS. MRP gene associated with a non-P-glycoprotein multidrug resistance encode a 190-kDa membrane bound glycoprotein. Cancer Res 1993; 53:3658-3661.
    • Krishnamachary N, Center MS. MRP gene associated with a non-P-glycoprotein multidrug resistance encode a 190-kDa membrane bound glycoprotein. Cancer Res 1993; 53:3658-3661.
  • 12
    • 4544357777 scopus 로고    scopus 로고
    • Investigation of MRP-1 protein and MDR-1 P-glycoprotein expression in invasive breast cancer: A prognostic study
    • Larkin A, O'Driscol L, Kennedy S, Purcell R, Moran E, Crown J, Parkinson M, Clynes M. Investigation of MRP-1 protein and MDR-1 P-glycoprotein expression in invasive breast cancer: a prognostic study. Int J cancer 2004; 112:286-294.
    • (2004) Int J cancer , vol.112 , pp. 286-294
    • Larkin, A.1    O'Driscol, L.2    Kennedy, S.3    Purcell, R.4    Moran, E.5    Crown, J.6    Parkinson, M.7    Clynes, M.8
  • 13
    • 15744363796 scopus 로고    scopus 로고
    • Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites
    • Letourneau IJ, Bowers RJ, Deeley RG, Cole SP. Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites. Toxicol Lett 2005; 157:9-19.
    • (2005) Toxicol Lett , vol.157 , pp. 9-19
    • Letourneau, I.J.1    Bowers, R.J.2    Deeley, R.G.3    Cole, S.P.4
  • 14
    • 0034072174 scopus 로고    scopus 로고
    • Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions
    • Bakos E, Evers R, Sinko E, Varadi A, Borst P, Sarkadi B. Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. Mol Pharmacol 2000; 57:760-768.
    • (2000) Mol Pharmacol , vol.57 , pp. 760-768
    • Bakos, E.1    Evers, R.2    Sinko, E.3    Varadi, A.4    Borst, P.5    Sarkadi, B.6
  • 17
    • 0037159933 scopus 로고    scopus 로고
    • Multidrug resistance protein 2 (MRP2) transport HIV protease inhibitors, and transport can be enhanced by other drugs
    • Huisman MT, Smit JW, Zelcer N, Wiltshire HR, Beijnen JH, Schinkel AH. Crommentuyn KM et al. Multidrug resistance protein 2 (MRP2) transport HIV protease inhibitors, and transport can be enhanced by other drugs. AIDS 2002; 16:2295-2301.
    • (2002) AIDS , vol.16 , pp. 2295-2301
    • Huisman, M.T.1    Smit, J.W.2    Zelcer, N.3    Wiltshire, H.R.4    Beijnen, J.H.5    Schinkel, A.H.6    Crommentuyn, K.M.7
  • 18
    • 0005014240 scopus 로고    scopus 로고
    • Gottesman MM, Pastan I' Ambudkar SV. P-glycoprotein and multidrug resistance. Curr Opin Genet Dev1996; 6:610-617.
    • Gottesman MM, Pastan I' Ambudkar SV. P-glycoprotein and multidrug resistance. Curr Opin Genet Dev1996; 6:610-617.
  • 19
    • 0031455482 scopus 로고    scopus 로고
    • Sharom FJ. P-glycoprotein efflux pump: how does it transport? J Membr Biol1997; 160: 161-175.
    • Sharom FJ. P-glycoprotein efflux pump: how does it transport? J Membr Biol1997; 160: 161-175.
  • 22
    • 0037229942 scopus 로고    scopus 로고
    • Role of P-glycoprotein in pharmacokinetics: Clinical implications
    • Lin JH, Yamazaki M. Role of P-glycoprotein in pharmacokinetics: clinical implications. Clin Pharmacokinet 2003; 42:59-98.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 59-98
    • Lin, J.H.1    Yamazaki, M.2
  • 23
    • 0033328139 scopus 로고    scopus 로고
    • The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions
    • Yu DK. The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions. J Clin Pharmacol 1999; 39:1203-1211.
    • (1999) J Clin Pharmacol , vol.39 , pp. 1203-1211
    • Yu, D.K.1
  • 27
    • 0033746295 scopus 로고    scopus 로고
    • Intracellular trafficking and regulation of canalicular ATP-binding cassette transporters
    • Kipp H, Arias IM. Intracellular trafficking and regulation of canalicular ATP-binding cassette transporters. Semin Liver Dis 2000; 20:339-351.
    • (2000) Semin Liver Dis , vol.20 , pp. 339-351
    • Kipp, H.1    Arias, I.M.2
  • 28
  • 29
    • 0031765907 scopus 로고    scopus 로고
    • Role of P-glycoprotein and cytochrome P450 3A4 in limiting oral absorption of peptides and peptidomimectics
    • Wacher VJ, Silverman JA, Zhang Y, Benet LZ. Role of P-glycoprotein and cytochrome P450 3A4 in limiting oral absorption of peptides and peptidomimectics. J Pharm Sci 1998; 87: 1322:1330.
    • (1998) J Pharm Sci , vol.87 , pp. 1322-1330
    • Wacher, V.J.1    Silverman, J.A.2    Zhang, Y.3    Benet, L.Z.4
  • 31
    • 0028054999 scopus 로고
    • Extrahepatic metabolism of drugs in human
    • Krishna DR, Koltz U. Extrahepatic metabolism of drugs in human. Clin Pharmacokinet 1994; 26:144-160.
    • (1994) Clin Pharmacokinet , vol.26 , pp. 144-160
    • Krishna, D.R.1    Koltz, U.2
  • 32
    • 0036223336 scopus 로고    scopus 로고
    • Nelson DR. introductory remarks on human CYPs. Drug Metab Rev 2002; 34:1-5.
    • Nelson DR. introductory remarks on human CYPs. Drug Metab Rev 2002; 34:1-5.
  • 33
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogrnomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogrnomics: translating functional genomics into rational therapeutics. Science 1999; 286:487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 34
    • 0029025655 scopus 로고
    • Recent advances: The cytochrome P450 enzymes
    • Slaughter RL, Edwdards DJ. Recent advances: the cytochrome P450 enzymes. Ann Pharmacother 1995; 29:619-624.
    • (1995) Ann Pharmacother , vol.29 , pp. 619-624
    • Slaughter, R.L.1    Edwdards, D.J.2
  • 35
    • 0037478407 scopus 로고    scopus 로고
    • Human extrahepatic cytochromes P450: Function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts
    • Ding X, Kaminsky LS. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol 2003; 43:149-173.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 149-173
    • Ding, X.1    Kaminsky, L.S.2
  • 36
    • 0037302804 scopus 로고    scopus 로고
    • Kidney CYP450 enzymes: Biological actions beyond drug metabolism
    • Zhao X, Imig JD. Kidney CYP450 enzymes: biological actions beyond drug metabolism. Curr Drug Metab 2003; 4:73-84.
    • (2003) Curr Drug Metab , vol.4 , pp. 73-84
    • Zhao, X.1    Imig, J.D.2
  • 37
    • 2942596244 scopus 로고    scopus 로고
    • Cytochrome P450 in neurological disease
    • Liu M, Hurn PD, Alkayed NJ. Cytochrome P450 in neurological disease. Curr Drug Metab 2004; 5:225-234.
    • (2004) Curr Drug Metab , vol.5 , pp. 225-234
    • Liu, M.1    Hurn, P.D.2    Alkayed, N.J.3
  • 38
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
    • Watkins PB, Wrighton SA, Schuetz E.G, Molowa DT, Guzelian PS. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J Clin Invest 1987; 80:1029-36.
    • (1987) J Clin Invest , vol.80 , pp. 1029-1036
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, E.G.3    Molowa, D.T.4    Guzelian, P.S.5
  • 39
    • 0342437515 scopus 로고    scopus 로고
    • Enzyme-catalyzed process of first-pass hepatic and intestinal drug extraction
    • Shen DD, Kunze KL, Thummel KE. Enzyme-catalyzed process of first-pass hepatic and intestinal drug extraction. Adv Drug Delivery Rev 1997; 27:99-127.
    • (1997) Adv Drug Delivery Rev , vol.27 , pp. 99-127
    • Shen, D.D.1    Kunze, K.L.2    Thummel, K.E.3
  • 40
    • 0026464616 scopus 로고
    • Identification of rifampin-inducible P540IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P540IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 1992; 90:1871-1878.
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 41
    • 0028113492 scopus 로고
    • Inter-patient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test
    • Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, Watkins PB. Inter-patient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test. Drug Metab Dispos 1994; 22:947-955.
    • (1994) Drug Metab Dispos , vol.22 , pp. 947-955
    • Lown, K.S.1    Kolars, J.C.2    Thummel, K.E.3    Barnett, J.L.4    Kunze, K.L.5    Wrighton, S.A.6    Watkins, P.B.7
  • 42
    • 0035104276 scopus 로고    scopus 로고
    • Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport
    • Katoh M, Nakajima M, Yamazaki H, Yokoi T. Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport. Eur J Pharm Sci. 2001; 12:505-513.
    • (2001) Eur J Pharm Sci , vol.12 , pp. 505-513
    • Katoh, M.1    Nakajima, M.2    Yamazaki, H.3    Yokoi, T.4
  • 43
    • 0033795486 scopus 로고    scopus 로고
    • Potential role of P-glycoprotein in affecting hepatic metabolism of drugs
    • Chiou WL, Chung SM, Wu TC. Potential role of P-glycoprotein in affecting hepatic metabolism of drugs. Pharm Res 2000; 17:903-905.
    • (2000) Pharm Res , vol.17 , pp. 903-905
    • Chiou, W.L.1    Chung, S.M.2    Wu, T.C.3
  • 44
    • 0034077338 scopus 로고    scopus 로고
    • Theoritical calculation and prediction of P-glycoprotein-interacting drugs using MolSurf parametrization and PLS statistics
    • Osterberg T, Norinder U. Theoritical calculation and prediction of P-glycoprotein-interacting drugs using MolSurf parametrization and PLS statistics. Eur J Pharm Sci 2000; 10:295-303.
    • (2000) Eur J Pharm Sci , vol.10 , pp. 295-303
    • Osterberg, T.1    Norinder, U.2
  • 45
    • 0029898576 scopus 로고    scopus 로고
    • Structural requirements for activity of propafenone-type modulators in P-glycoprotein-mediated multidrug resistance
    • Chiba P, Ecker G, Schmid D, Drach J, Tell B, Goldenberg S, Gekeler V. Structural requirements for activity of propafenone-type modulators in P-glycoprotein-mediated multidrug resistance. Mol Pharmcol 1996; 49:1122-1130.
    • (1996) Mol Pharmcol , vol.49 , pp. 1122-1130
    • Chiba, P.1    Ecker, G.2    Schmid, D.3    Drach, J.4    Tell, B.5    Goldenberg, S.6    Gekeler, V.7
  • 46
    • 0342762062 scopus 로고    scopus 로고
    • The barrier functions of CYP3A4 and P-glycoprotein in the small bowel
    • Watkins PB. The barrier functions of CYP3A4 and P-glycoprotein in the small bowel. Adv Drug Deliv Rev 1997; 27: 161-70.
    • (1997) Adv Drug Deliv Rev , vol.27 , pp. 161-170
    • Watkins, P.B.1
  • 47
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • Wacher VJ, Wu CY, Benet LZ. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol Carcinog 1995;13: 129-134.
    • (1995) Mol Carcinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.Y.2    Benet, L.Z.3
  • 48
    • 5444251235 scopus 로고    scopus 로고
    • In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: Changes in P-gp and CYP3A4 activity
    • Patel J, Buddha B, Dey S, Pal D, Mitra AK. In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity. Am J Ther 2004; 11:262-277.
    • (2004) Am J Ther , vol.11 , pp. 262-277
    • Patel, J.1    Buddha, B.2    Dey, S.3    Pal, D.4    Mitra, A.K.5
  • 51
    • 33745574979 scopus 로고    scopus 로고
    • Drug interactions in cancer therapy
    • Scripture CD, Figg WD. Drug interactions in cancer therapy. Nature Rev/Cancer 2006; 6:546-558.
    • (2006) Nature Rev/Cancer , vol.6 , pp. 546-558
    • Scripture, C.D.1    Figg, W.D.2
  • 55
    • 0035003021 scopus 로고    scopus 로고
    • Role of formulation vehicle in taxane pharmacology
    • van Zuylen L, Verweij J, Sparreboom A. Role of formulation vehicle in taxane pharmacology. Invest New Drug 2001; 19:125-141.
    • (2001) Invest New Drug , vol.19 , pp. 125-141
    • van Zuylen, L.1    Verweij, J.2    Sparreboom, A.3
  • 56
    • 10344248680 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by SDZ PSC 833 combined with VAD (vincristine, doxorubicin, dexamethasone) in refractory multiple myeloma. A phase I study
    • Sonneveld P, Marie JP, Huisman C. Reversal of multidrug resistance by SDZ PSC 833 combined with VAD (vincristine, doxorubicin, dexamethasone) in refractory multiple myeloma. A phase I study. Leukemia 1996; 10:1741-1750.
    • (1996) Leukemia , vol.10 , pp. 1741-1750
    • Sonneveld, P.1    Marie, J.P.2    Huisman, C.3
  • 57
    • 22144434701 scopus 로고    scopus 로고
    • Drug-drug interactions in oncology: Why are they important and can they be minimized?
    • Blower P, de Wit R, Goodin S, Aapro M. Drug-drug interactions in oncology: Why are they important and can they be minimized? Crit Rev Oncol Hematol 2005; 55:117-142.
    • (2005) Crit Rev Oncol Hematol , vol.55 , pp. 117-142
    • Blower, P.1    de Wit, R.2    Goodin, S.3    Aapro, M.4
  • 58
    • 0029880344 scopus 로고    scopus 로고
    • Characterization of the cytochrome P450 enzymes involved in the invitro metabolism of dolassetrone. Comparison with other indole-containing 5-HT3 antagonists
    • Sanwald P, David M, Dow J. Characterization of the cytochrome P450 enzymes involved in the invitro metabolism of dolassetrone. Comparison with other indole-containing 5-HT3 antagonists. Drug Metab Dispos 1996; 24:602-609.
    • (1996) Drug Metab Dispos , vol.24 , pp. 602-609
    • Sanwald, P.1    David, M.2    Dow, J.3
  • 63
    • 24944465760 scopus 로고    scopus 로고
    • CYP1A1 is major enzyme responsible for the metabolism of granisetron in human liver microsomes
    • Nakamura H, Ariyoshi N, Okada K, Nakasa H, Nakazawa K, Kitada M. CYP1A1 is major enzyme responsible for the metabolism of granisetron in human liver microsomes. Curr Drug Metab 2005; 6:469-480.
    • (2005) Curr Drug Metab , vol.6 , pp. 469-480
    • Nakamura, H.1    Ariyoshi, N.2    Okada, K.3    Nakasa, H.4    Nakazawa, K.5    Kitada, M.6
  • 65
    • 0034053590 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics of oxazaphosphorines
    • Boddy AV, Yule SM. Metabolism and pharmacokinetics of oxazaphosphorines. Clin Pharmacokinet 2000; 38:291-304.
    • (2000) Clin Pharmacokinet , vol.38 , pp. 291-304
    • Boddy, A.V.1    Yule, S.M.2
  • 66
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and isofosphamide by cytochrome P450 2B and 3A in human liver microsomes
    • Chang TK, Weber CF, Crespi CL, Waxman DJ. Differential activation of cyclophosphamide and isofosphamide by cytochrome P450 2B and 3A in human liver microsomes. Cancer Res 1993; 53:5629-5637.
    • (1993) Cancer Res , vol.53 , pp. 5629-5637
    • Chang, T.K.1    Weber, C.F.2    Crespi, C.L.3    Waxman, D.J.4
  • 67
    • 16244385619 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of imatinib mesylate
    • Leveque D, Maloisel F. Clinical pharmacokinetics of imatinib mesylate. In Vivo 2005; 19:77-84.
    • (2005) In Vivo , vol.19 , pp. 77-84
    • Leveque, D.1    Maloisel, F.2
  • 68
    • 33847172401 scopus 로고    scopus 로고
    • Gleevec product information
    • Novartis Pharmaceuticals Corporation, online
    • Novartis Pharmaceuticals Corporation. Gleevec product information. Norvatis [online], http://www.pharma.us.novartis.com/product/pi/pdf/ gleevec_tabs.pdf. 2005.
    • (2005) Norvatis
  • 71
  • 72
    • 20444499136 scopus 로고    scopus 로고
    • Effect of gefitinib on the systemic disposition of intravenous irrinotecan (IRN) in pediatric patients with refractory solid tumors
    • Iacono LC, Furman WL, Crews KR, Panetta JC, Freeman BB, Daw NC, Stewart CF. Effect of gefitinib on the systemic disposition of intravenous irrinotecan (IRN) in pediatric patients with refractory solid tumors. J Clin Oncol 2004; 22:2011.
    • (2004) J Clin Oncol , vol.22 , pp. 2011
    • Iacono, L.C.1    Furman, W.L.2    Crews, K.R.3    Panetta, J.C.4    Freeman, B.B.5    Daw, N.C.6    Stewart, C.F.7
  • 74
    • 0042343743 scopus 로고    scopus 로고
    • Carboxylesterasemediated sensitization of human tumor cells to CPT-11 can not override ABCG2imediated drug resistance
    • Wierdl M, Wall A, Morton CL, Sampath J, Danks MK, Schuetz JD, Potter PM. Carboxylesterasemediated sensitization of human tumor cells to CPT-11 can not override ABCG2imediated drug resistance. Mol Pharmacol 2003; 64:279-288.
    • (2003) Mol Pharmacol , vol.64 , pp. 279-288
    • Wierdl, M.1    Wall, A.2    Morton, C.L.3    Sampath, J.4    Danks, M.K.5    Schuetz, J.D.6    Potter, P.M.7
  • 75
    • 0030922974 scopus 로고    scopus 로고
    • Multidrug resistance-reversing agents increase vinblastin distribution in normal tissues expressing the P-glycoprotein but do not enhance drug penetration in brain and testis
    • Arboix M, Paz OG, Colombo T, D'Incalci M. Multidrug resistance-reversing agents increase vinblastin distribution in normal tissues expressing the P-glycoprotein but do not enhance drug penetration in brain and testis. J pharmacol Exp Ther 1997; 281:1226-1230.
    • (1997) J pharmacol Exp Ther , vol.281 , pp. 1226-1230
    • Arboix, M.1    Paz, O.G.2    Colombo, T.3    D'Incalci, M.4
  • 77
  • 80
    • 0021092701 scopus 로고
    • The influence of aminoglycosides on nephrotoxicity of cis-diamminedichloroplatinum in cancer patients
    • Haas A, Anderson L, Lad T. The influence of aminoglycosides on nephrotoxicity of cis-diamminedichloroplatinum in cancer patients. J Infect Dis 1983; 147:363.
    • (1983) J Infect Dis , vol.147 , pp. 363
    • Haas, A.1    Anderson, L.2    Lad, T.3
  • 81
    • 0024428166 scopus 로고
    • Evaluation of aminoglycoside disposition in patients previously treated with cisplatin
    • Christensen ML, Stewart CF, Crom WR. Evaluation of aminoglycoside disposition in patients previously treated with cisplatin. Ther Drug Monit 1989; 11:631-636.
    • (1989) Ther Drug Monit , vol.11 , pp. 631-636
    • Christensen, M.L.1    Stewart, C.F.2    Crom, W.R.3
  • 82
    • 0031038330 scopus 로고    scopus 로고
    • Effect of cisplatin and amphotericin B on DNA adduct formation and toxicity in malignant glioma and normal tissues in rat
    • Bergstrom P, Johnsson A, Cavallin-Stahl E, Bergenheim T, Henriksson R. Effect of cisplatin and amphotericin B on DNA adduct formation and toxicity in malignant glioma and normal tissues in rat. Eur J Cancer 1997; 33:153-159.
    • (1997) Eur J Cancer , vol.33 , pp. 153-159
    • Bergstrom, P.1    Johnsson, A.2    Cavallin-Stahl, E.3    Bergenheim, T.4    Henriksson, R.5
  • 83
    • 33847114050 scopus 로고    scopus 로고
    • Genentech, Inc, Genentec [online
    • Genentech, Inc. Rituxan product information. Genentec [online], http://www.gene.com/gene/product/information/pdf/rituxan-prescribing.pdf 2001.
    • (2001) Rituxan product information
  • 84
    • 1842627704 scopus 로고    scopus 로고
    • Vinorelbine-induced acute reversible peripheral neuropathy in patient with ovarian carcinoma pretreated with carboplatin and paclitaxel
    • Scalone S, Sorio R, Bortolussi R, Lombardi D, La Mura N, Veronesi A. Vinorelbine-induced acute reversible peripheral neuropathy in patient with ovarian carcinoma pretreated with carboplatin and paclitaxel. Acta Oncol 2004; 43:209-211.
    • (2004) Acta Oncol , vol.43 , pp. 209-211
    • Scalone, S.1    Sorio, R.2    Bortolussi, R.3    Lombardi, D.4    La Mura, N.5    Veronesi, A.6
  • 85
    • 0029762644 scopus 로고    scopus 로고
    • Severe neurotoxicity from vinorelbine-paclitaxel combinations
    • Parimoo D, Jeffers S, Muggia FM. Severe neurotoxicity from vinorelbine-paclitaxel combinations. J Natl Cancer Inst 1996; 88:1079-1080.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1079-1080
    • Parimoo, D.1    Jeffers, S.2    Muggia, F.M.3
  • 86
    • 0033009537 scopus 로고    scopus 로고
    • Potential interaction of antiretroviral therapy with paclitaxel in patients with AIDs-related Kaposi's sarcoma
    • Schwartz JD, Howard W, Scadden DT. Potential interaction of antiretroviral therapy with paclitaxel in patients with AIDs-related Kaposi's sarcoma. Aids 1999; 13:283-284.
    • (1999) Aids , vol.13 , pp. 283-284
    • Schwartz, J.D.1    Howard, W.2    Scadden, D.T.3
  • 87
    • 33847161331 scopus 로고    scopus 로고
    • Agenerase [package insert, Research Triangle Park, NC: Glaxo Wellcome Inc; 2004
    • Agenerase [package insert]. Research Triangle Park, NC: Glaxo Wellcome Inc; 2004.
  • 88
    • 0042444801 scopus 로고    scopus 로고
    • Steady state pharmacokinetic (PK) interaction study of atazanavir (ATV) with clarithromycin (CLR) in healthy subjects
    • September 27-30; San Diego, California, Abs, H-1717
    • Mummaneni V, Randall D, Chabuel D, Steady state pharmacokinetic (PK) interaction study of atazanavir (ATV) with clarithromycin (CLR) in healthy subjects. 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Diego, California. 2002; Abs. #H-1717.
    • (2002) 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Mummaneni, V.1    Randall, D.2    Chabuel, D.3
  • 89
    • 33847174263 scopus 로고    scopus 로고
    • Norvir [package insert] 2005; North Chicago, IL: Abbott Laboratories
    • Norvir [package insert] 2005; North Chicago, IL: Abbott Laboratories.
  • 90
    • 33847096913 scopus 로고    scopus 로고
    • Fortovase [package insert] 2003; Basel, Switzerland: F. Hoffman-La Roche Ltd
    • Fortovase [package insert] 2003; Basel, Switzerland: F. Hoffman-La Roche Ltd.
  • 92
    • 0033325440 scopus 로고    scopus 로고
    • The effect of azithromycin on the pharmacokinetics of indinavir
    • Foulds G, LaBoy-Goral L, Wei GC, Apseloff G. The effect of azithromycin on the pharmacokinetics of indinavir. J Clin Pharmacol 1999; 39:842-846.
    • (1999) J Clin Pharmacol , vol.39 , pp. 842-846
    • Foulds, G.1    LaBoy-Goral, L.2    Wei, G.C.3    Apseloff, G.4
  • 93
    • 33847104735 scopus 로고    scopus 로고
    • Kaletra [package insert] 2005; North Chicago, IL: Abbott Laboratories; Oct
    • Kaletra [package insert] 2005; North Chicago, IL: Abbott Laboratories; Oct.
  • 94
    • 33847129327 scopus 로고    scopus 로고
    • Fiske W, Benedek IH. Pharmacokinetics of efavirenz (EFV) and ritonavir (RIT) after multiple oral doses in healthy volunteers.12th International Conference on AIDS; June 28-July 3; Geneva, Switzerland.1998; Abst. #42269.
    • Fiske W, Benedek IH. Pharmacokinetics of efavirenz (EFV) and ritonavir (RIT) after multiple oral doses in healthy volunteers.12th International Conference on AIDS; June 28-July 3; Geneva, Switzerland.1998; Abst. #42269.
  • 96
    • 33847173846 scopus 로고    scopus 로고
    • Aptivus [package insert] 2005; Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc, Nov
    • Aptivus [package insert] 2005; Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; Nov.
  • 99
    • 33847138256 scopus 로고    scopus 로고
    • Reyataz [package insert, Princeton, NJ: Bristol-Myers Squibb Company; Jan. 2006
    • Reyataz [package insert], Princeton, NJ: Bristol-Myers Squibb Company; Jan. 2006.
  • 100
    • 0042444800 scopus 로고    scopus 로고
    • Pharmacokinetic effect of rifabutin on atazanavir with and without ritonavir in healthy subjects
    • Feb 24-28; Seattle, Washington, Abst #445
    • Agarwala S, Mummaneni V, Randall D. Pharmacokinetic effect of rifabutin on atazanavir with and without ritonavir in healthy subjects. 9th Conference on Retroviruses and Opportunistic Infections; Feb 24-28; Seattle, Washington 2002; Abst #445.
    • (2002) 9th Conference on Retroviruses and Opportunistic Infections
    • Agarwala, S.1    Mummaneni, V.2    Randall, D.3
  • 101
    • 33847132870 scopus 로고    scopus 로고
    • CDC Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. 2000, Jan 28, [AIDS Treatment Information Service: Current Treatment] Available at: http://www.hivatis.org/trtgdlns.html.
    • CDC Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. 2000, Jan 28, [AIDS Treatment Information Service: Current Treatment] Available at: http://www.hivatis.org/trtgdlns.html.
  • 102
    • 33847163291 scopus 로고    scopus 로고
    • Crixivan [package insert] 2005; Whitehouse Station, NJ: Merck & Co, Inc, Oct
    • Crixivan [package insert] 2005; Whitehouse Station, NJ: Merck & Co., Inc.; Oct.
  • 103
    • 0345982987 scopus 로고    scopus 로고
    • Steady-state pharmacokinetic interaction of modified-dose indinavir and rifabutin
    • Jan 30-Feb 2; San Francisco, California, Abst #90
    • Hamzeh F, Benson C, Gerber J. Steady-state pharmacokinetic interaction of modified-dose indinavir and rifabutin. 7th Conference on Retroviruses and Opportunistic Infections; Jan 30-Feb 2; San Francisco, California. 2000; Abst #90.
    • (2000) 7th Conference on Retroviruses and Opportunistic Infections
    • Hamzeh, F.1    Benson, C.2    Gerber, J.3
  • 104
    • 33847112552 scopus 로고    scopus 로고
    • Viracept [package insert] 2004; La Jolla, CA: Agouron Pharmaceuticals, Inc, Sept
    • Viracept [package insert] 2004; La Jolla, CA: Agouron Pharmaceuticals, Inc.; Sept.
  • 108
    • 0031939246 scopus 로고    scopus 로고
    • Systemic antifungal agents: Drug interactions of clinical significance
    • Albengres E, Le Louet H, Tillement JP. Systemic antifungal agents: drug interactions of clinical significance. Drug Saf 1998;18:83-97.
    • (1998) Drug Saf , vol.18 , pp. 83-97
    • Albengres, E.1    Le Louet, H.2    Tillement, J.P.3
  • 109
    • 0035041368 scopus 로고    scopus 로고
    • The interaction of saquinavir with ketoconazole, erythromycin and rifampicin: Comparison of the effect in healthy volunteers and in HIV-infected patients
    • Grub S, Bryson H, Goggin T, Ludin E, Jorga K. The interaction of saquinavir with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. Eur J Clin Pharmacol 2001; 57: 115-121.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 115-121
    • Grub, S.1    Bryson, H.2    Goggin, T.3    Ludin, E.4    Jorga, K.5
  • 110
    • 33847118172 scopus 로고    scopus 로고
    • Sporanox [package insert] 2000; Titusville, NJ: Janssen Pharmaceutica
    • Sporanox [package insert] 2000; Titusville, NJ: Janssen Pharmaceutica.
  • 112
    • 85088600996 scopus 로고    scopus 로고
    • Indinavir-fluconazole interaction. [letter]
    • Bellibas SE. Indinavir-fluconazole interaction. [letter] Antimicrob Agents Chemother 1999; 43:432-33.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 432-433
    • Bellibas, S.E.1
  • 114
    • 0034830154 scopus 로고    scopus 로고
    • Koks CH, Crommentuyn KM, Hoetelmans RM, Burger DM, Koopmans PP, Mathot RA, Mulder JW, Meenhorst PL, Beijnen JH.Koks CH, Crommentuyn KM, Hoetelmans RM. The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1 infected individuals. Br J Clin Pharmacol 2001; 51:631-635.
    • Koks CH, Crommentuyn KM, Hoetelmans RM, Burger DM, Koopmans PP, Mathot RA, Mulder JW, Meenhorst PL, Beijnen JH.Koks CH, Crommentuyn KM, Hoetelmans RM. The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1 infected individuals. Br J Clin Pharmacol 2001; 51:631-635.
  • 115
    • 32944472661 scopus 로고    scopus 로고
    • OSI Pharmaceuticals Inc. & Genentech Inc;, Genentec, online
    • OSI Pharmaceuticals Inc. & Genentech Inc; Tarceva prescribing information: Genentec 2005; [online], http://www.gene.com/gene/products/ information/oncology/tarceva/insert.jsp.
    • (2005) Tarceva prescribing information
  • 116
    • 0000604128 scopus 로고    scopus 로고
    • A phase I study of CYP3A4 modulation of oral etoposide with ketoconazole in patients with advanced cancer
    • Abstract
    • Kobayashi K, Ratain MJ, Fleming GF, Vogelzang NJ, Cooper N, Sun BL. A phase I study of CYP3A4 modulation of oral etoposide with ketoconazole in patients with advanced cancer. Proc. Am Soc Clin Oncol 1996; 15: Abstract # 1489.
    • Proc. Am Soc Clin Oncol , vol.1996 , Issue.15 , pp. 1489
    • Kobayashi, K.1    Ratain, M.J.2    Fleming, G.F.3    Vogelzang, N.J.4    Cooper, N.5    Sun, B.L.6
  • 117
    • 0005127640 scopus 로고    scopus 로고
    • The effect of the induction and inhibition of CyP3A4 on the pharmacokinetics of single oral dose of ZD1839(Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TK) in healthy male volunteers
    • Abstract
    • Swaisland H, Smith RP, Farebrother J, Laight A. The effect of the induction and inhibition of CyP3A4 on the pharmacokinetics of single oral dose of ZD1839(Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TK) in healthy male volunteers. Proc. Am Soc Clin Oncol 2002; 21: Abstract # 83.
    • Proc. Am Soc Clin Oncol , vol.2002 , Issue.21 , pp. 83
    • Swaisland, H.1    Smith, R.P.2    Farebrother, J.3    Laight, A.4
  • 120
    • 33847139124 scopus 로고    scopus 로고
    • Lexiva [package insert] 2005; Research Triangle Park, NC: Glaxo Wellcome Inc; Nov
    • Lexiva [package insert] 2005; Research Triangle Park, NC: Glaxo Wellcome Inc; Nov.
  • 121
    • 0002105970 scopus 로고    scopus 로고
    • Concomitant administration of ABT-378/ritonavir. Results in a clinically important pharmacokinectic interaction with atorvastatin but not pravastatin
    • September 17-20; Toronto, Canada, Abst #1644
    • Carr RA, Andre AK, Bertz RJ. Concomitant administration of ABT-378/ritonavir. Results in a clinically important pharmacokinectic interaction with atorvastatin but not pravastatin. 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20; Toronto, Canada. 2000; Abst #1644.
    • (2000) 40th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Carr, R.A.1    Andre, A.K.2    Bertz, R.J.3
  • 122
    • 0035185490 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between nelfinavir and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and simvastatin
    • Hsyu PH, Schultz-Smith MD, Lillibridge JH, Lewis RH, Kerr BM. Pharmacokinetic interactions between nelfinavir and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and simvastatin. Antimicrob Agents Chemother 2001; 45:3445-3450.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 3445-3450
    • Hsyu, P.H.1    Schultz-Smith, M.D.2    Lillibridge, J.H.3    Lewis, R.H.4    Kerr, B.M.5
  • 124
    • 0032005580 scopus 로고    scopus 로고
    • Potentiated antitumor activity effects of cisplatin and lovostatin against MmB16 melanoma in mice
    • Feleszko W, Zagozdzon R, Golab J, Jakobisiak M. Potentiated antitumor activity effects of cisplatin and lovostatin against MmB16 melanoma in mice. Eur J Cancer 34:406-411.
    • Eur J Cancer , vol.34 , pp. 406-411
    • Feleszko, W.1    Zagozdzon, R.2    Golab, J.3    Jakobisiak, M.4
  • 125
    • 0032766426 scopus 로고    scopus 로고
    • Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells
    • Agarwal B, Bhendwal S, Halmos B, Moss SF, Ramey WG, Holt PR. Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. Clin Cancer Res 1999; 5:2223-2229.
    • (1999) Clin Cancer Res , vol.5 , pp. 2223-2229
    • Agarwal, B.1    Bhendwal, S.2    Halmos, B.3    Moss, S.F.4    Ramey, W.G.5    Holt, P.R.6
  • 126
    • 0035552572 scopus 로고    scopus 로고
    • Synergistic interaction of lovastatin and paclitaxel in human cancer cells
    • Holstein SA, Hohl RJ. Synergistic interaction of lovastatin and paclitaxel in human cancer cells. Mol Cancer Ther 2001; 1:141-149.
    • (2001) Mol Cancer Ther , vol.1 , pp. 141-149
    • Holstein, S.A.1    Hohl, R.J.2
  • 127
    • 2542458153 scopus 로고    scopus 로고
    • Potential antitumor effects of statins (Review)
    • Jakobisiak M, Golab J. Potential antitumor effects of statins (Review). Int J Oncol 2003; 23:1055-1069.
    • (2003) Int J Oncol , vol.23 , pp. 1055-1069
    • Jakobisiak, M.1    Golab, J.2
  • 128
    • 0034639643 scopus 로고    scopus 로고
    • Piscitelli S.C., Burstein A.H., Chaitt D., Alfaro R.M., Falloon J. Indinavir concentrations and St John's wort. Lancet 2000 a; 355(9203): 547-548.
    • Piscitelli S.C., Burstein A.H., Chaitt D., Alfaro R.M., Falloon J. Indinavir concentrations and St John's wort. Lancet 2000 a; 355(9203): 547-548.
  • 131
    • 0028807793 scopus 로고
    • Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes
    • Chieli E, Romiti N, Cervelli F, Tongiani R. Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes. Life Sci 1995; 57:1741-1751.
    • (1995) Life Sci , vol.57 , pp. 1741-1751
    • Chieli, E.1    Romiti, N.2    Cervelli, F.3    Tongiani, R.4
  • 133
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
    • Shapiro AB, Ling V. Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem Pharmacol 1997; 53:587-596.
    • (1997) Biochem Pharmacol , vol.53 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 135
    • 0035671937 scopus 로고    scopus 로고
    • Saint John's wort: An in vitro analysis of P-glycoprotein induction due to extended exposure
    • Perloff MD, von Moltke LL, Stormer E, Shader RI, Greenblatt DJ. Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure. Br J Pharmacol 2001; 134:1601-1608.
    • (2001) Br J Pharmacol , vol.134 , pp. 1601-1608
    • Perloff, M.D.1    von Moltke, L.L.2    Stormer, E.3    Shader, R.I.4    Greenblatt, D.J.5
  • 136
    • 0034639638 scopus 로고    scopus 로고
    • Acute heart transplant rejection due to Saint John's wort
    • Ruschitzka F, Meier PJ, Turina M, Luscher TF, Noll G. Acute heart transplant rejection due to Saint John's wort. Lancet 2000; 355 (9203):548-549.
    • (2000) Lancet , vol.355 , Issue.9203 , pp. 548-549
    • Ruschitzka, F.1    Meier, P.J.2    Turina, M.3    Luscher, T.F.4    Noll, G.5
  • 138
  • 140
    • 0033763121 scopus 로고    scopus 로고
    • Interaction of Hypericum perforatum (St. John's wort) with cyclosporin A metabolism in a patient after liver transplantation
    • Karliova M, Treichel U, Malago M, Frilling A, Gerken G, Broelsch CE. Interaction of Hypericum perforatum (St. John's wort) with cyclosporin A metabolism in a patient after liver transplantation. J Hepatol 2000; 33:853-855.
    • (2000) J Hepatol , vol.33 , pp. 853-855
    • Karliova, M.1    Treichel, U.2    Malago, M.3    Frilling, A.4    Gerken, G.5    Broelsch, C.E.6
  • 141
    • 0034639580 scopus 로고    scopus 로고
    • Safety of St John's wort (Hypericum perforatum)
    • Yue QY, Bergquist C, Gerden B. Safety of St John's wort (Hypericum perforatum). Lancet 2000; 355(9203): 576-577.
    • (2000) Lancet , vol.355 , Issue.9203 , pp. 576-577
    • Yue, Q.Y.1    Bergquist, C.2    Gerden, B.3
  • 142
    • 0036304016 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between herbal remedies and medicinal drugs
    • Ioannides C. Pharmacokinetic interactions between herbal remedies and medicinal drugs. Xenobiotica 2002; 32: 451-478.
    • (2002) Xenobiotica , vol.32 , pp. 451-478
    • Ioannides, C.1
  • 144
    • 0033600191 scopus 로고    scopus 로고
    • Glucuronidation of 7-ethyl-10-hydroxycampothecin (SN-38) by human UDP-glucuronosyltransferases encoded at the UGT1 locus
    • Ciotti M, Basu N, Brangi M, Owens IS. Glucuronidation of 7-ethyl-10-hydroxycampothecin (SN-38) by human UDP-glucuronosyltransferases encoded at the UGT1 locus. Biochem Biophys Res Commun 1999; 260:199-202.
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 199-202
    • Ciotti, M.1    Basu, N.2    Brangi, M.3    Owens, I.S.4
  • 146
    • 0031723235 scopus 로고    scopus 로고
    • Prediction of pharmacokinetic alterations caused by drug-drug interactions: Metabolic interaction in the liver
    • Ito K, Iwatsubo T, Kanamitsu S, Ueda K, Suzuki H, Sugiyama Y.1998.Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver. Pharmacol Rev 1998; 50:387-412.
    • (1998) Pharmacol Rev 1998 , vol.50 , pp. 387-412
    • Ito, K.1    Iwatsubo, T.2    Kanamitsu, S.3    Ueda, K.4    Suzuki, H.5    Sugiyama, Y.6
  • 147
    • 0034532081 scopus 로고    scopus 로고
    • Oral bioavailability of active principles from herbal products in humans. A study on Hypericum perforatum extracts using the soft gelatin capsule technology
    • Agrosi M, Mischiatti S, Harrasser PC, Savio D. 2000.Oral bioavailability of active principles from herbal products in humans. A study on Hypericum perforatum extracts using the soft gelatin capsule technology. Phytomedicine 2000; 7:455-462.
    • (2000) Phytomedicine 2000 , vol.7 , pp. 455-462
    • Agrosi, M.1    Mischiatti, S.2    Harrasser, P.C.3    Savio, D.4
  • 148
    • 0031779971 scopus 로고    scopus 로고
    • Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers
    • Biber A, Fischer H, Romer A, Chatterjee SS. Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers. Pharmacopsychiatry, 1998; 31 Suppl 1: 36-43.
    • (1998) Pharmacopsychiatry , vol.31 , Issue.SUPPL. 1 , pp. 36-43
    • Biber, A.1    Fischer, H.2    Romer, A.3    Chatterjee, S.S.4
  • 149
    • 0034060357 scopus 로고    scopus 로고
    • Inhibitory effect of natural furanocoumarins on human microsomal cytochrome P450 3A activity
    • Guo LQ, Taniguchi M, Xiao YQ, Baba K, Ohta T, Yamazoe Y. Inhibitory effect of natural furanocoumarins on human microsomal cytochrome P450 3A activity. Jpn J Pharmacol 2000; 82:122-129.
    • (2000) Jpn J Pharmacol , vol.82 , pp. 122-129
    • Guo, L.Q.1    Taniguchi, M.2    Xiao, Y.Q.3    Baba, K.4    Ohta, T.5    Yamazoe, Y.6
  • 150
    • 0030839243 scopus 로고    scopus 로고
    • Drug interactions eith grapefood juice
    • Ameer B, Weintraub RA. Drug interactions eith grapefood juice. Clin Pharmacokinetics 1997; 33:103-121.
    • (1997) Clin Pharmacokinetics , vol.33 , pp. 103-121
    • Ameer, B.1    Weintraub, R.A.2
  • 151
    • 0029101508 scopus 로고
    • Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice
    • Hukkinen SK, Varhe A, Olkkola KT, Neuvonen PJ. Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice. Clin Pharmcol Ther 1995; 58:127-131.
    • (1995) Clin Pharmcol Ther , vol.58 , pp. 127-131
    • Hukkinen, S.K.1    Varhe, A.2    Olkkola, K.T.3    Neuvonen, P.J.4
  • 152
    • 0033917295 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 enzymes by constituents of St. John's wort, an herbal preparation used in the treatment of depression
    • Obach RS. Inhibition of human cytochrome P450 enzymes by constituents of St. John's wort, an herbal preparation used in the treatment of depression. J Pharmacol Exp Ther 2000; 294:88-95.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 88-95
    • Obach, R.S.1
  • 153
    • 0042950000 scopus 로고    scopus 로고
    • Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects
    • Dresser GK, Schwarz UI, Wilkinson GR, Kim RB. Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects. Clin Pharmacol Ther 2003; 73: 41-50.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 41-50
    • Dresser, G.K.1    Schwarz, U.I.2    Wilkinson, G.R.3    Kim, R.B.4
  • 157
    • 0033826492 scopus 로고    scopus 로고
    • Wentworth JM, Agostini M, Love J, Schwabe JW, Chatterjee VK. St John's wort, a herbal antidepressant, activates the steroid X receptor. J Endocrinol 2000; 166:R11-16.
    • Wentworth JM, Agostini M, Love J, Schwabe JW, Chatterjee VK. St John's wort, a herbal antidepressant, activates the steroid X receptor. J Endocrinol 2000; 166:R11-16.
  • 158
    • 0036186534 scopus 로고    scopus 로고
    • John's wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
    • Bray BJ, Perry NB, Menkes DB, Rosengren RJ. St. John's wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse. Toxicol Sci 2002; 66:27-33.
    • (2002) Toxicol Sci , vol.66 , pp. 27-33
    • Bray, B.J.1    Perry, N.B.2    Menkes, D.B.3    Rosengren, R.J.4    St5
  • 162
    • 0036591445 scopus 로고    scopus 로고
    • Club drugs: Methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate
    • Smith KM, Larive LL, Romanelli F. Club drugs: methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate. Am J Health Syst Pharm 2002; 59:1067-1076.
    • (2002) Am J Health Syst Pharm , vol.59 , pp. 1067-1076
    • Smith, K.M.1    Larive, L.L.2    Romanelli, F.3
  • 163
    • 0034671674 scopus 로고    scopus 로고
    • Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression
    • Ladona MG, Gonzalez ML, Rane A, Peter RM, de la Torre R. Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression. Life Sci 2000; 68:431-443.
    • (2000) Life Sci , vol.68 , pp. 431-443
    • Ladona, M.G.1    Gonzalez, M.L.2    Rane, A.3    Peter, R.M.4    de la Torre, R.5
  • 165
    • 0031834159 scopus 로고    scopus 로고
    • Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity
    • Bornheim L. Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity. Toxicol Appl Pharmacol 1998;150:158-165.
    • (1998) Toxicol Appl Pharmacol , vol.150 , pp. 158-165
    • Bornheim, L.1
  • 167
    • 0033547191 scopus 로고    scopus 로고
    • Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate
    • Harrington RD, Woodward JA, Hooton TM, Horn JR. Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate. Arch Intern Med 1999; 159:2221-2224.
    • (1999) Arch Intern Med , vol.159 , pp. 2221-2224
    • Harrington, R.D.1    Woodward, J.A.2    Hooton, T.M.3    Horn, J.R.4
  • 169
    • 0032576351 scopus 로고    scopus 로고
    • Fatal interaction between ritonavir and MDMA
    • Henry J, Hill I. Fatal interaction between ritonavir and MDMA. Lancet 1998; 352:1751-1752.
    • (1998) Lancet , vol.352 , pp. 1751-1752
    • Henry, J.1    Hill, I.2
  • 171
    • 0034653801 scopus 로고    scopus 로고
    • Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ("Ecstasy")
    • Maurer HH, Bickeboeller-Friedrich J, Kraemer T, Peters FT. Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ("Ecstasy"). Toxicol Lett 2000; 112/113:133-142.
    • (2000) Toxicol Lett , vol.112-113 , pp. 133-142
    • Maurer, H.H.1    Bickeboeller-Friedrich, J.2    Kraemer, T.3    Peters, F.T.4
  • 173
    • 0347762493 scopus 로고    scopus 로고
    • P-Glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine, and paramethoxyamphetamine
    • Ketabi-Kiyanvash N, Weiss J, Haefeli WE, Mikus G. P-Glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine, and paramethoxyamphetamine. Addict Biol 2003; 8:413-418.
    • (2003) Addict Biol , vol.8 , pp. 413-418
    • Ketabi-Kiyanvash, N.1    Weiss, J.2    Haefeli, W.E.3    Mikus, G.4
  • 177
    • 0037369176 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: Theory and clinical reality, part I
    • Armstrong SC, Cozza KL. Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: theory and clinical reality, part I. Psychosomatics 2003a; 44:167-171.
    • (2003) Psychosomatics , vol.44 , pp. 167-171
    • Armstrong, S.C.1    Cozza, K.L.2
  • 178
    • 0242299162 scopus 로고    scopus 로고
    • Armstrong SC, Cozza KL. Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: theory and clinical reality, part II. Psychosomatics2003b; 44:515-520.
    • Armstrong SC, Cozza KL. Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: theory and clinical reality, part II. Psychosomatics2003b; 44:515-520.
  • 179
    • 0034024545 scopus 로고    scopus 로고
    • The effect of ritonavir on the pharmacokinetics of meperidine and normeperidine
    • Piscitelli SC, Kress DR, Bertz RJ, Pau A, Davey R. The effect of ritonavir on the pharmacokinetics of meperidine and normeperidine. Pharmacotherapy 2000b; 20:549-553.
    • (2000) Pharmacotherapy , vol.20 , pp. 549-553
    • Piscitelli, S.C.1    Kress, D.R.2    Bertz, R.J.3    Pau, A.4    Davey, R.5
  • 180
    • 0026648389 scopus 로고
    • Pharmacokinetic interactions of Zidovudine and methadone in intravenous drug-using patients with HIV infections
    • Schwartz EL, Brechbuhl AB, Khal P. Pharmacokinetic interactions of Zidovudine and methadone in intravenous drug-using patients with HIV infections. J Acquir Immune Defic Syndr 1992; 5:619-626.
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 619-626
    • Schwartz, E.L.1    Brechbuhl, A.B.2    Khal, P.3
  • 182
    • 0031774469 scopus 로고    scopus 로고
    • Nevirapine/didanosine/lavivudine once daily in HIV-1-infected intravenous drug users
    • Stazewski S, Haberl A, Gute P. Nevirapine/didanosine/lavivudine once daily in HIV-1-infected intravenous drug users. Antivir Ther 1998; 3 (suppl 4):55-56.
    • (1998) Antivir Ther , vol.3 , Issue.SUPPL. 4 , pp. 55-56
    • Stazewski, S.1    Haberl, A.2    Gute, P.3
  • 183
    • 0033044075 scopus 로고    scopus 로고
    • Nevirapine induced opiate withdrawal among injection drug users with HIV infection receiving methadone
    • Altice FL, Friedland GH, Cooney EL. Nevirapine induced opiate withdrawal among injection drug users with HIV infection receiving methadone. AIDS. 1999;13:957-962.
    • (1999) AIDS , vol.13 , pp. 957-962
    • Altice, F.L.1    Friedland, G.H.2    Cooney, E.L.3
  • 184
    • 0032564624 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of methadone in HIV-infected patients receiving protease inhibitors (letter)
    • Beauverie P, Taburet AM, Dessalles MC, Furlan V, Touzeau D. Therapeutic drug monitoring of methadone in HIV-infected patients receiving protease inhibitors (letter). AIDS 1998; 12:2510-2511.
    • (1998) AIDS , vol.12 , pp. 2510-2511
    • Beauverie, P.1    Taburet, A.M.2    Dessalles, M.C.3    Furlan, V.4    Touzeau, D.5
  • 185
    • 0034062132 scopus 로고    scopus 로고
    • Methadone withdrawal symptoms with nevirapine and efavirenz (letter)
    • Pinzani V, Faucherre V, Peyreire H, Blayac JP. Methadone withdrawal symptoms with nevirapine and efavirenz (letter). Ann Pharmacother 2000; 34:405-407.
    • (2000) Ann Pharmacother , vol.34 , pp. 405-407
    • Pinzani, V.1    Faucherre, V.2    Peyreire, H.3    Blayac, J.P.4
  • 189
    • 0027454958 scopus 로고
    • Inhibition of cytochrome P450 2D6 (CYP2D6) by methadone
    • Wu D, Otton SV, Sproule BA. Inhibition of cytochrome P450 2D6 (CYP2D6) by methadone. Br J Clin Pharmac Ther 1993; 35:30-34.
    • (1993) Br J Clin Pharmac Ther , vol.35 , pp. 30-34
    • Wu, D.1    Otton, S.V.2    Sproule, B.A.3
  • 192
    • 0031868559 scopus 로고    scopus 로고
    • The effect of fluconazole on the clinical pharmokinetics of methadone
    • Cobb M, Desai J, Brown LS. The effect of fluconazole on the clinical pharmokinetics of methadone. Clinical Pharmacol Ther 1998; 63:655-662.
    • (1998) Clinical Pharmacol Ther , vol.63 , pp. 655-662
    • Cobb, M.1    Desai, J.2    Brown, L.S.3
  • 193
    • 0033123321 scopus 로고    scopus 로고
    • Methadone and antiretroviral medications, Parts 1 & 2
    • and
    • Gourevitch MN, Friedland GF. Methadone and antiretroviral medications, Parts 1 & 2. AIDS Clin Care 1999; 11:30-31 and 37-46.
    • (1999) AIDS Clin Care , vol.11
    • Gourevitch, M.N.1    Friedland, G.F.2
  • 194
    • 0032754284 scopus 로고    scopus 로고
    • The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
    • Greiner B, Eichelbaum M, Fritz P. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest 1999; 104:147-53.
    • (1999) J Clin Invest , vol.104 , pp. 147-153
    • Greiner, B.1    Eichelbaum, M.2    Fritz, P.3
  • 195
    • 0029916534 scopus 로고    scopus 로고
    • P-glycoprotein: A major determinant of rifampicin-inducible expression of cytochrome P450 3A4 in mice and humans
    • Schuetz EG, Schinkel AH, Relling MV, Schuetz JD. P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P450 3A4 in mice and humans. Proc Natl Acad Sci USA 1996; 93:4001-4005.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4001-4005
    • Schuetz, E.G.1    Schinkel, A.H.2    Relling, M.V.3    Schuetz, J.D.4
  • 196
    • 33847128488 scopus 로고    scopus 로고
    • Penzak S, Shen J, Alfar R, Remaley A, Falloon J. Influence of low-dose ritonavir on the pharmacokinetics of the P-glycoprotein (P-gp) substrate digoxin. Program and abstracts of the 4th International Workshop on Clinical Pharmacology of HIV Therapy 2003; March 27-29, Cannes, France. Abstract 2.6.
    • Penzak S, Shen J, Alfar R, Remaley A, Falloon J. Influence of low-dose ritonavir on the pharmacokinetics of the P-glycoprotein (P-gp) substrate digoxin. Program and abstracts of the 4th International Workshop on Clinical Pharmacology of HIV Therapy 2003; March 27-29, Cannes, France. Abstract 2.6.
  • 197
    • 0032401711 scopus 로고    scopus 로고
    • l Pharmacokinetic interaction between saquinavir and cyclosporine
    • Brinkman K, Huysmans F, Burger DM.l Pharmacokinetic interaction between saquinavir and cyclosporine. Ann Intern Med 1998; 129:914-915.
    • (1998) Ann Intern Med , vol.129 , pp. 914-915
    • Brinkman, K.1    Huysmans, F.2    Burger, D.M.3
  • 198
    • 3242723840 scopus 로고    scopus 로고
    • The MDR1 (ABCB1) gene polymorphism and its clinical implications
    • Ieiri I, Takane H, Ostubo K. The MDR1 (ABCB1) gene polymorphism and its clinical implications. Clin Pharmacokinet 2004; 43:553-576.
    • (2004) Clin Pharmacokinet , vol.43 , pp. 553-576
    • Ieiri, I.1    Takane, H.2    Ostubo, K.3
  • 199
    • 13944274619 scopus 로고    scopus 로고
    • Clinical and toxicological relevance of CYP2C9: Drug-drug interactions and pharmacogenetics
    • Rettie AE, Jones JP. Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics. Annu Rev Pharmacol Toxicol. 2005; 45:477-94.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 477-494
    • Rettie, A.E.1    Jones, J.P.2
  • 200
    • 0036667955 scopus 로고    scopus 로고
    • MDR1 single neucleotide polymorphisms: Multiplicity of haplotypes and functional consequences
    • Kim RB. MDR1 single neucleotide polymorphisms: multiplicity of haplotypes and functional consequences. Pharmacogenetics 2002; 12:425-427.
    • (2002) Pharmacogenetics , vol.12 , pp. 425-427
    • Kim, R.B.1
  • 202
    • 0032937986 scopus 로고    scopus 로고
    • The Physiological and pharmacological roles of P450 isoenzymes
    • Chang GWM, Kam PC. The Physiological and pharmacological roles of P450 isoenzymes. Anaesthesia 1999; 54:42-50.
    • (1999) Anaesthesia , vol.54 , pp. 42-50
    • Chang, G.W.M.1    Kam, P.C.2
  • 203
    • 20144378997 scopus 로고    scopus 로고
    • IIe 118Val genetic polymorphism of Cyp3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients
    • Wang A, Yu BN, Luo CH, Tan ZR, Zhou G, Wang LS, Zhang W, Li Z, Liu J, Zhou HH. IIe 118Val genetic polymorphism of Cyp3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients. Eur J Clin Pharmacol 2005; 60:843-848.
    • (2005) Eur J Clin Pharmacol , vol.60 , pp. 843-848
    • Wang, A.1    Yu, B.N.2    Luo, C.H.3    Tan, Z.R.4    Zhou, G.5    Wang, L.S.6    Zhang, W.7    Li, Z.8    Liu, J.9    Zhou, H.H.10
  • 205
    • 0024581065 scopus 로고
    • Leucovorin enhancement of the effects of the fluoropyridines on thymidylate synthase
    • Morgan RG. Leucovorin enhancement of the effects of the fluoropyridines on thymidylate synthase. Cancer 1989; 63:1008- 1012.
    • (1989) Cancer , vol.63 , pp. 1008-1012
    • Morgan, R.G.1
  • 206
    • 17744418861 scopus 로고    scopus 로고
    • Kohne CH, Wils J, Lorenz M, Schoffski P, Voigtmann R, Bokemeyer C, Lutz M, Kleeberg C, Ridwelski K, Souchon R, El-Serafi M, Weiss U, Burkhard O, Ruckle H, Lichnitser M, Langenbuch T, Scheithauer W, Baron B, Couvreur ML, Schmoll HJ; Randomized phase III study of high dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin verses bolus fluorouracil plus leucovorin in advanced colorectal cancer. European Organization of Research and Treatment of Cancer Gastrointestional Group Study 40952. J Clin Oncol 2003; 21:3721-3728.
    • Kohne CH, Wils J, Lorenz M, Schoffski P, Voigtmann R, Bokemeyer C, Lutz M, Kleeberg C, Ridwelski K, Souchon R, El-Serafi M, Weiss U, Burkhard O, Ruckle H, Lichnitser M, Langenbuch T, Scheithauer W, Baron B, Couvreur ML, Schmoll HJ; Randomized phase III study of high dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin verses bolus fluorouracil plus leucovorin in advanced colorectal cancer. European Organization of Research and Treatment of Cancer Gastrointestional Group Study 40952. J Clin Oncol 2003; 21:3721-3728.
  • 207
    • 0026004795 scopus 로고
    • Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethazone: Does it reduce the antitumor therapeutic efficacy
    • Shiloni E, Matzner Y. Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethazone: does it reduce the antitumor therapeutic efficacy. Blood 1991; 78:1389-1390.
    • (1991) Blood , vol.78 , pp. 1389-1390
    • Shiloni, E.1    Matzner, Y.2
  • 208
    • 0025250697 scopus 로고
    • Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethazone: Prevention of acquired neutrophill chemotaxis defect and differential suppression of interleukin-2-associated side effects
    • Mier JW. Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethazone: prevention of acquired neutrophill chemotaxis defect and differential suppression of interleukin-2-associated side effects. Blood 1990; 76:1933-1940.
    • (1990) Blood , vol.76 , pp. 1933-1940
    • Mier, J.W.1
  • 209
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs
    • Kronbach T, Fischer V, Meyer UA. Cyclosporine metabolism in human liver identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs. Clin Pharmacol Ther 1988; 43(6), 630-5.
    • (1988) Clin Pharmacol Ther , vol.43 , Issue.6 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 210
    • 0032556549 scopus 로고    scopus 로고
    • Hypericum perforatum (St John's wort) in depression: Pest or blessing?
    • Rey JM, Walter G. Hypericum perforatum (St John's wort) in depression: pest or blessing? Med J Aust 1998; 169:583-586.
    • (1998) Med J Aust , vol.169 , pp. 583-586
    • Rey, J.M.1    Walter, G.2
  • 213
    • 0030735733 scopus 로고    scopus 로고
    • Metabolism of the tricyclic antidepressant amitriptyline by cDNA-expressed human cytochrome P450 enzymes
    • Olesen OV, Linnet K. Metabolism of the tricyclic antidepressant amitriptyline by cDNA-expressed human cytochrome P450 enzymes. Pharmacology1997; 55:235-243.
    • Pharmacology1997 , vol.55 , pp. 235-243
    • Olesen, O.V.1    Linnet, K.2
  • 215
    • 0033314052 scopus 로고    scopus 로고
    • Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): Implications for interactions with enzyme-inducing drugs
    • Venkatakrishnan K, von Moltke LL, Greenblatt DJ. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs. J Clin Pharmacol 1999; 39:567-577.
    • (1999) J Clin Pharmacol , vol.39 , pp. 567-577
    • Venkatakrishnan, K.1    von Moltke, L.L.2    Greenblatt, D.J.3
  • 216
    • 0028929645 scopus 로고
    • Metabolism of theophylline by cDNA-expressed human cytochromes P-450
    • Ha HR, Chen J, Freiburghaus AU, Follath F. Metabolism of theophylline by cDNA-expressed human cytochromes P-450. Br J Clin Pharmacol 1995; 39:321-326.
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 321-326
    • Ha, H.R.1    Chen, J.2    Freiburghaus, A.U.3    Follath, F.4
  • 217
    • 0032793959 scopus 로고    scopus 로고
    • OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
    • Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, Kim RB. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab Dispos 1999; 27:866-871.
    • (1999) Drug Metab Dispos , vol.27 , pp. 866-871
    • Cvetkovic, M.1    Leake, B.2    Fromm, M.F.3    Wilkinson, G.R.4    Kim, R.B.5
  • 218
    • 0036288273 scopus 로고    scopus 로고
    • Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates
    • Tian R, Koyabu N, Takanaga H, Matsuo H, Ohtani H, Sawada Y. Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates. Pharm Res 2002; 19: 802-809.
    • (2002) Pharm Res , vol.19 , pp. 802-809
    • Tian, R.1    Koyabu, N.2    Takanaga, H.3    Matsuo, H.4    Ohtani, H.5    Sawada, Y.6
  • 219
    • 0031015345 scopus 로고    scopus 로고
    • Human P450 metabolism of warfarin
    • Kaminsky LS, Zhang ZY. Human P450 metabolism of warfarin. Pharmacol Ther 1997; 73:67-74.
    • (1997) Pharmacol Ther , vol.73 , pp. 67-74
    • Kaminsky, L.S.1    Zhang, Z.Y.2
  • 221
    • 0030430035 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
    • Kumar GN, Rodrigues AD, Buko AM, Denissen JF. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 1996; 277: 423-431.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 423-431
    • Kumar, G.N.1    Rodrigues, A.D.2    Buko, A.M.3    Denissen, J.F.4
  • 222
    • 0034821939 scopus 로고    scopus 로고
    • Role of transport proteins in drug absorption, distribution and excretion
    • Ayrton A, Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica 2001; 31:469-497.
    • (2001) Xenobiotica , vol.31 , pp. 469-497
    • Ayrton, A.1    Morgan, P.2
  • 223
    • 0031448854 scopus 로고    scopus 로고
    • The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone
    • Moody DE, Alburges ME, Parker RJ, Collins JM, Strong JM. The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone. Drug Metab Dispos 1997; 25:1347-1353.
    • (1997) Drug Metab Dispos , vol.25 , pp. 1347-1353
    • Moody, D.E.1    Alburges, M.E.2    Parker, R.J.3    Collins, J.M.4    Strong, J.M.5
  • 225
    • 0028825399 scopus 로고
    • Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
    • Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest 1995; 96:1698-1705.
    • (1995) J Clin Invest , vol.96 , pp. 1698-1705
    • Schinkel, A.H.1    Wagenaar, E.2    van Deemter, L.3    Mol, C.A.4    Borst, P.5
  • 226
    • 0031748173 scopus 로고    scopus 로고
    • In vitro and in vivo drug interactions involving human CYP3A
    • Thummel KE, Wilkinson GR. In vitro and in vivo drug interactions involving human CYP3A. Annu Rev Pharmacol Toxicol 1998; 38:389-430.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 389-430
    • Thummel, K.E.1    Wilkinson, G.R.2
  • 228
    • 0034020386 scopus 로고    scopus 로고
    • Barbenel DM, Yusufi B, O'Shea D, Bench CJ. Mania in a patient receiving testosterone replacement postorchidectomy taking St John's wort and sertraline. J Psychopharmacol 2000; 14:84-86.
    • Barbenel DM, Yusufi B, O'Shea D, Bench CJ. Mania in a patient receiving testosterone replacement postorchidectomy taking St John's wort and sertraline. J Psychopharmacol 2000; 14:84-86.
  • 229
    • 0034106493 scopus 로고    scopus 로고
    • Consumer use of St. John's wort: A survey on effectiveness, safety, and tolerability
    • Beckman SE, Sommi RW, Switzer J. Consumer use of St. John's wort: a survey on effectiveness, safety, and tolerability. Pharmacotherapy 2000; 20:568-574.
    • (2000) Pharmacotherapy , vol.20 , pp. 568-574
    • Beckman, S.E.1    Sommi, R.W.2    Switzer, J.3
  • 230
    • 1842847407 scopus 로고    scopus 로고
    • Possible serotonin syndrome after combination of buspirone and St John's Wort
    • Dannawi M. Possible serotonin syndrome after combination of buspirone and St John's Wort. J Psychopharmacol 2002; 16:401.
    • (2002) J Psychopharmacol , vol.16 , pp. 401
    • Dannawi, M.1
  • 231
    • 0032032735 scopus 로고    scopus 로고
    • SSRIs and St.John's Wort: Possible toxicity?
    • Gordon JB. SSRIs and St.John's Wort: possible toxicity? Am Fam Physician 1998; 57: 950-953.
    • (1998) Am Fam Physician , vol.57 , pp. 950-953
    • Gordon, J.B.1
  • 235
    • 0036243269 scopus 로고    scopus 로고
    • Hypomania induced by herbal and pharmaceutical psychotropic medicines following mild traumatic brain injury
    • Spinella M, Eaton LA. Hypomania induced by herbal and pharmaceutical psychotropic medicines following mild traumatic brain injury. Brain Inj 2002; 16:359-367.
    • (2002) Brain Inj , vol.16 , pp. 359-367
    • Spinella, M.1    Eaton, L.A.2
  • 236
    • 0000203223 scopus 로고    scopus 로고
    • Interaction of St John's wort extract with phenprocoumon
    • Maurer A JA, Bauer S. Interaction of St John's wort extract with phenprocoumon. Eur J Clin Pharmacol 1999; 55:22.
    • (1999) Eur J Clin Pharmacol , vol.55 , pp. 22
    • Maurer, A.J.1    Bauer, S.2
  • 237
    • 0033547648 scopus 로고    scopus 로고
    • Second thoughts about safety of St John's wort
    • Ernst E. Second thoughts about safety of St John's wort. Lancet 1999; 354(9195):2014-2016.
    • (1999) Lancet , vol.354 , Issue.9195 , pp. 2014-2016
    • Ernst, E.1
  • 240
    • 0031024382 scopus 로고    scopus 로고
    • Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: Potential contribution to high first-pass metabolism
    • Fitzsimmons ME, Collins JM. Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism. Drug Metab Dispos 1997; 25: 256-266.
    • (1997) Drug Metab Dispos , vol.25 , pp. 256-266
    • Fitzsimmons, M.E.1    Collins, J.M.2
  • 241
    • 0032914931 scopus 로고    scopus 로고
    • Potential metabolic interaction between St. John's wort and theophylline
    • Nebel A, Schneider BJ, Baker RK, Kroll DJ. Potential metabolic interaction between St. John's wort and theophylline. Ann Pharmacother 1999: 33:502.
    • (1999) Ann Pharmacother , vol.33 , pp. 502
    • Nebel, A.1    Schneider, B.J.2    Baker, R.K.3    Kroll, D.J.4
  • 242
    • 0026508999 scopus 로고
    • Characterization of human liver cytochromes P-450 involved in theophylline metabolism
    • Sarkar MA, Hunt C, Guzelian PS, Karnes HT. Characterization of human liver cytochromes P-450 involved in theophylline metabolism. Drug Metab Dispos 1992; 20:31-37.
    • (1992) Drug Metab Dispos , vol.20 , pp. 31-37
    • Sarkar, M.A.1    Hunt, C.2    Guzelian, P.S.3    Karnes, H.T.4
  • 244
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs
    • Kronbach T, Fischer V, Meyer UA. Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs. Clin Pharmacol Ther 1988; 43:630-635.
    • (1988) Clin Pharmacol Ther , vol.43 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 245
    • 0034720558 scopus 로고    scopus 로고
    • Profound drop of cyclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum)
    • Breidenbach T, Kliem V, Burg M, Radermacher J, Hoffmann M W, Klempnauer J. Profound drop of cyclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum). Transplantation 2000b: 69:2229-2230.
    • (2000) Transplantation , vol.69 , pp. 2229-2230
    • Breidenbach, T.1    Kliem, V.2    Burg, M.3    Radermacher, J.4    Hoffmann, M.W.5    Klempnauer, J.6
  • 246
    • 0035956720 scopus 로고    scopus 로고
    • Barone GW, Gurley BJ, Abul-Ezz SR. Herbal supplements: a potential for drug interactions in transplant recipients.Transplatation 2001; 71:239-241.
    • Barone GW, Gurley BJ, Abul-Ezz SR. Herbal supplements: a potential for drug interactions in transplant recipients.Transplatation 2001; 71:239-241.
  • 247
    • 10744232730 scopus 로고    scopus 로고
    • Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients
    • Bauer S, Stormer E, Johne A, Kruger H, Budde K, Neumayer HH, Roots I, and Mai I. Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients. Br J Clin Pharmacol 2003; 55:203-211.
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 203-211
    • Bauer, S.1    Stormer, E.2    Johne, A.3    Kruger, H.4    Budde, K.5    Neumayer, H.H.6    Roots, I.7    Mai, I.8
  • 248
    • 0034598569 scopus 로고    scopus 로고
    • Drug interactions with Hypericum. Is nature not so mild after all?. Interview by Petra Eiden]
    • Roots I. [Drug interactions with Hypericum. Is nature not so mild after all?. Interview by Petra Eiden]. MMW Fortschr Med 2000; 142:14.
    • (2000) MMW Fortschr Med , vol.142 , pp. 14
    • Roots, I.1
  • 249
    • 0000006828 scopus 로고    scopus 로고
    • Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)
    • Johne A, Brockmoller J, Bauer S, Maurer A, Langheinrich M, Roots I. Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum). Clin Pharmacol Ther 1999; 66:338-345.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 338-345
    • Johne, A.1    Brockmoller, J.2    Bauer, S.3    Maurer, A.4    Langheinrich, M.5    Roots, I.6
  • 251
    • 0036229852 scopus 로고    scopus 로고
    • Drugs as P-glycoprotein substrates, inhibitors, and inducers
    • Kim BR. Drugs as P-glycoprotein substrates, inhibitors, and inducers. Drug Metab Rev 2002; 34:47-54.
    • (2002) Drug Metab Rev , vol.34 , pp. 47-54
    • Kim, B.R.1
  • 253
    • 0032456884 scopus 로고    scopus 로고
    • Clinically important pharmacokinetic drug-drug interactions: Role of cytochrome P450 enzymes
    • Tanaka E. Clinically important pharmacokinetic drug-drug interactions: role of cytochrome P450 enzymes. J Clin Phar Ther 1998; 23:403-416.
    • (1998) J Clin Phar Ther , vol.23 , pp. 403-416
    • Tanaka, E.1


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