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Volumn 50, Issue 3, 1998, Pages 387-411

Prediction of pharmacokinetic alterations caused by drug-drug interactions: Metabolic interaction in the liver

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DRUG;

EID: 0031723235     PISSN: 00316997     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (493)

References (93)
  • 2
    • 0023924549 scopus 로고
    • In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulfonamides and quinolines
    • Back DJ, Tjia JF, Karbwang J and Colbert J (1988) In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulfonamides and quinolines. Br J Clin Pharmacol 26:23-29.
    • (1988) Br J Clin Pharmacol , vol.26 , pp. 23-29
    • Back, D.J.1    Tjia, J.F.2    Karbwang, J.3    Colbert, J.4
  • 4
    • 0345448082 scopus 로고    scopus 로고
    • Problems and progress: From Bio-International '89 to the present
    • Tokyo, Japan, April 22-24
    • Benet LZ (1996) Problems and progress: From Bio-International '89 to the present, in FIP Bio-International '96, Tokyo, Japan, April 22-24. pp 9-13.
    • (1996) FIP Bio-International '96 , pp. 9-13
    • Benet, L.Z.1
  • 5
    • 0026552617 scopus 로고
    • Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction
    • Bergstrom RF, Peyton AL and Lemberger L (1992) Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction. Clin Pharmacol Ther 51:239-248.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 239-248
    • Bergstrom, R.F.1    Peyton, A.L.2    Lemberger, L.3
  • 6
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • Bertz RJ and Granneman GR (1997) Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 32:210-258.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 7
    • 0029553030 scopus 로고
    • Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor
    • Chiba M, Nishime JA and Lin JH (1995) Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor. J Pharmacol Exp Ther 275:1527-1534.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1527-1534
    • Chiba, M.1    Nishime, J.A.2    Lin, J.H.3
  • 8
    • 0002570237 scopus 로고
    • Sulphaphenazole-induced hypoglycaemic attacks in tolbutamide-treated diabetics
    • Christensen LK, Hansen JM and Kristensen M (1963) Sulphaphenazole-induced hypoglycaemic attacks in tolbutamide-treated diabetics. Lancet 2:1298-1301.
    • (1963) Lancet , vol.2 , pp. 1298-1301
    • Christensen, L.K.1    Hansen, J.M.2    Kristensen, M.3
  • 11
    • 0022550597 scopus 로고
    • Effect of (E)-5-(2-Bromovinyl)uracil on the catabolism and anti-tumor activity of 5-fluorouracil in rats and leukemic mice
    • Desgranges C, Razaka G, De Clercq E, Herdewijn P, Balzarini J, Drouillet F and Bricaud H (1986) Effect of (E)-5-(2-Bromovinyl)uracil on the catabolism and anti-tumor activity of 5-fluorouracil in rats and leukemic mice. Cancer Res 46:1094-1101.
    • (1986) Cancer Res , vol.46 , pp. 1094-1101
    • Desgranges, C.1    Razaka, G.2    De Clercq, E.3    Herdewijn, P.4    Balzarini, J.5    Drouillet, F.6    Bricaud, H.7
  • 12
    • 0025344378 scopus 로고
    • Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
    • de Waziers I, Cugnenc PH, Yang CS, Leroux J-P and Beaune PH (1990) Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. J Pharmacol Exp Ther 253:387-394.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 387-394
    • De Waziers, I.1    Cugnenc, P.H.2    Yang, C.S.3    Leroux, J.-P.4    Beaune, P.H.5
  • 13
    • 0019952111 scopus 로고
    • Pharmacokinetics and biotransformation studies of terfenadine in man
    • Garteiz DA, Hook RH, Walker BJ and Okerholm RA (1982) Pharmacokinetics and biotransformation studies of terfenadine in man. Arzneim-Forsch 32:1185-1190.
    • (1982) Arzneim-Forsch , vol.32 , pp. 1185-1190
    • Garteiz, D.A.1    Hook, R.H.2    Walker, B.J.3    Okerholm, R.A.4
  • 14
  • 17
    • 0026457407 scopus 로고
    • Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
    • Hebert MF, Roberts JP, Prueksaritanont T and Benet LZ (1992) Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction. Clin Pharmacol Ther 52:453-457.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 453-457
    • Hebert, M.F.1    Roberts, J.P.2    Prueksaritanont, T.3    Benet, L.Z.4
  • 18
    • 0026671408 scopus 로고
    • Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin
    • Honig PK, Woosley RL, Zamani K, Conner DP and Cantilena LR Jr (1992) Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin. Clin Pharmacol Ther 52:231-238.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 231-238
    • Honig, P.K.1    Woosley, R.L.2    Zamani, K.3    Conner, D.P.4    Cantilena Jr., L.R.5
  • 20
    • 0020424170 scopus 로고
    • Mechanisms of p-aminohippurate transport by brush-border and basolateral membrane vesicles isolated from rat kidney cortex
    • Hori R, Takano M, Okano T, Kitazawa S and Inui K (1982) Mechanisms of p-aminohippurate transport by brush-border and basolateral membrane vesicles isolated from rat kidney cortex. Biochim Biophys Acta 692:97-100.
    • (1982) Biochim Biophys Acta , vol.692 , pp. 97-100
    • Hori, R.1    Takano, M.2    Okano, T.3    Kitazawa, S.4    Inui, K.5
  • 21
    • 7844245907 scopus 로고
    • Oral administration of procaine penicillin with and without benemid p-(di-n-propylsulphanyl) benzoic acid
    • Hunter WC (1951) Oral administration of procaine penicillin with and without benemid p-(di-n-propylsulphanyl) benzoic acid. Lancet 261:105.
    • (1951) Lancet , vol.261 , pp. 105
    • Hunter, W.C.1
  • 22
    • 0031777718 scopus 로고    scopus 로고
    • Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism together with binding and transport
    • Ito K, Iwatsubo T, Kanamitsu S, Nakajima Y and Sugiyama Y (1998) Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism together with binding and transport. Anna Rev Pharmacol Toxicol, 38:461-499.
    • (1998) Anna Rev Pharmacol Toxicol , vol.38 , pp. 461-499
    • Ito, K.1    Iwatsubo, T.2    Kanamitsu, S.3    Nakajima, Y.4    Sugiyama, Y.5
  • 24
    • 0029950964 scopus 로고    scopus 로고
    • Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics
    • Iwatsubo T, Hirota N, Ooie T, Suzuki H and Sugiyama Y (1996) Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics. Biopharm Drug Dispos 17:273-310.
    • (1996) Biopharm Drug Dispos , vol.17 , pp. 273-310
    • Iwatsubo, T.1    Hirota, N.2    Ooie, T.3    Suzuki, H.4    Sugiyama, Y.5
  • 25
    • 0027996327 scopus 로고
    • Terfenadine metabolism in human liver: In vitro inhibition by macrolide antibiotics and azole antifungals
    • Jurima-Romet M, Crawford K, Cyr T and Inaba T (1994) Terfenadine metabolism in human liver: In vitro inhibition by macrolide antibiotics and azole antifungals. Drug Metab Dispos 22:849-857.
    • (1994) Drug Metab Dispos , vol.22 , pp. 849-857
    • Jurima-Romet, M.1    Crawford, K.2    Cyr, T.3    Inaba, T.4
  • 26
    • 0030483808 scopus 로고    scopus 로고
    • Evaluation of drug interactions in intact hepatocytes: Inhibitors of terfenadine metabolism
    • Jurima-Romet M, Huang HS, Beck DJ and Li AP (1996) Evaluation of drug interactions in intact hepatocytes: Inhibitors of terfenadine metabolism. Toxicol In Vitro 10:655-663.
    • (1996) Toxicol in Vitro , vol.10 , pp. 655-663
    • Jurima-Romet, M.1    Huang, H.S.2    Beck, D.J.3    Li, A.P.4
  • 27
    • 0026094528 scopus 로고
    • Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities
    • Kalow W and Tang BK (1991) Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities. Clin Pharmacol Ther 50:508-519.
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 508-519
    • Kalow, W.1    Tang, B.K.2
  • 29
    • 0025719746 scopus 로고
    • First-pass metabolism of cyclosporin by the gut
    • Kolars JC, Awni WM, Merion RM and Watkins PB (1991) First-pass metabolism of cyclosporin by the gut. Lancet 338:1488-1490.
    • (1991) Lancet , vol.338 , pp. 1488-1490
    • Kolars, J.C.1    Awni, W.M.2    Merion, R.M.3    Watkins, P.B.4
  • 30
    • 0026464616 scopus 로고
    • Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C and Watkins PB (1992) Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 90:1871-1878.
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 31
    • 0027380074 scopus 로고
    • Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline
    • Kunze KL and Trager WF (1993) Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline. Chem Res Toxicol 6:649-656.
    • (1993) Chem Res Toxicol , vol.6 , pp. 649-656
    • Kunze, K.L.1    Trager, W.F.2
  • 32
    • 0031691234 scopus 로고    scopus 로고
    • The role of p-glycoprotein and canalicular multispecific organic anion transporter (cMOAT) in the hepatobiliary excretion of drugs
    • in press
    • Kusuhara H, Suzuki H and Sugiyama Y (1998) The role of p-glycoprotein and canalicular multispecific organic anion transporter (cMOAT) in the hepatobiliary excretion of drugs. J Pharm Sci, in press.
    • (1998) J Pharm Sci
    • Kusuhara, H.1    Suzuki, H.2    Sugiyama, Y.3
  • 33
    • 0023941798 scopus 로고
    • Deposition of nine metabolites of cyclosporine in human tissues, bile, urine, and whole blood
    • Lensmeyer GL, Wiebe DA and Carlson IH (1988) Deposition of nine metabolites of cyclosporine in human tissues, bile, urine, and whole blood. Transplant Proc 20:614-622.
    • (1988) Transplant Proc , vol.20 , pp. 614-622
    • Lensmeyer, G.L.1    Wiebe, D.A.2    Carlson, I.H.3
  • 34
    • 0030803654 scopus 로고    scopus 로고
    • Applications of primary human hepatocytea in the evaluation of pharmacokinetic drug-drug interactions: Evaluation of model drugs terfenadine and rifampin
    • Li AP and Jurima-Romet M (1997) Applications of primary human hepatocytea in the evaluation of pharmacokinetic drug-drug interactions: Evaluation of model drugs terfenadine and rifampin. Cell Biol Toxicol 13:365-374.
    • (1997) Cell Biol Toxicol , vol.13 , pp. 365-374
    • Li, A.P.1    Jurima-Romet, M.2
  • 38
    • 0025323155 scopus 로고
    • Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents
    • Murray M and Reidy GF (1990) Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents. Pharmacol Rev 42:85-101.
    • (1990) Pharmacol Rev , vol.42 , pp. 85-101
    • Murray, M.1    Reidy, G.F.2
  • 39
    • 0028283927 scopus 로고
    • 2 receptor antagonists, cimetidine and nizatidine, into isolated rat hepatocytes: Contribution of Type 1 system
    • 2 receptor antagonists, cimetidine and nizatidine, into isolated rat hepatocytes: Contribution of Type 1 system. J Pharmacol Exp Ther 269:1220-1227.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 1220-1227
    • Nakamura, H.1    Sano, H.2    Yamazaki, M.3    Sugiyama, Y.4
  • 40
    • 0013613778 scopus 로고
    • Kinetics of carboxytolbutamide excretion following tolbutamide and carboxytolbutamide administration
    • Nelson E and O'Reilly I (1961) Kinetics of carboxytolbutamide excretion following tolbutamide and carboxytolbutamide administration. J Pharmacol Exp Ther 132:103-109.
    • (1961) J Pharmacol Exp Ther , vol.132 , pp. 103-109
    • Nelson, E.1    O'Reilly, I.2
  • 42
    • 0006329350 scopus 로고
    • Mechanism of lethal toxicity exerted by simultaneous administration of the new antiviral, sorivudine, and the antitumor agent, Tegafur
    • Okuda H, Nishiyama T, Ogura K, Nagayama S, Ikeda K, Yamaguchi S, Nakamura Y, Kawaguchi Y and Watabe T (1995) Mechanism of lethal toxicity exerted by simultaneous administration of the new antiviral, sorivudine, and the antitumor agent, Tegafur, Xenobio Metabol Dispos 10(Suppl):166-169.
    • (1995) Xenobio Metabol Dispos , vol.10 , Issue.SUPPL. , pp. 166-169
    • Okuda, H.1    Nishiyama, T.2    Ogura, K.3    Nagayama, S.4    Ikeda, K.5    Yamaguchi, S.6    Nakamura, Y.7    Kawaguchi, Y.8    Watabe, T.9
  • 47
    • 0025134337 scopus 로고
    • Cyclosporin A drug interactions: Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes
    • Pichard L, Fabre I, Fabre G, Domergue J, Saint Aubert B, Mourad G and Maurel P (1990) Cyclosporin A drug interactions: Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab Dispos 18:595-605.
    • (1990) Drug Metab Dispos , vol.18 , pp. 595-605
    • Pichard, L.1    Fabre, I.2    Fabre, G.3    Domergue, J.4    Saint Aubert, B.5    Mourad, G.6    Maurel, P.7
  • 48
    • 0025219954 scopus 로고
    • Serious adverse effects of combining fluoxetine and tricyclic antidepressants
    • Preskorn SH, Beber JH, Faul JC and Hirschfeld RMA (1990) Serious adverse effects of combining fluoxetine and tricyclic antidepressants [letter]. Am J Psychiatry 147:532.
    • (1990) Am J Psychiatry , vol.147 , pp. 532
    • Preskorn, S.H.1    Beber, J.H.2    Faul, J.C.3    Hirschfeld, R.M.A.4
  • 49
    • 0028303820 scopus 로고
    • Plasma protein binding displacement interactions-why are they still regarded as clinically important?
    • Rolan PE (1994) Plasma protein binding displacement interactions-why are they still regarded as clinically important? Br J Clin Pharmacol 37:125-128.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 125-128
    • Rolan, P.E.1
  • 52
    • 0028840847 scopus 로고
    • Possible involvement of multiple P-glycoproteinmediated efflux systems in the transport of verapamil and other organic cations across rat intestine
    • Saitoh H and Aungst BJ (1995) Possible involvement of multiple P-glycoproteinmediated efflux systems in the transport of verapamil and other organic cations across rat intestine. Pharmaceut Res 12:1304-1310.
    • (1995) Pharmaceut Res , vol.12 , pp. 1304-1310
    • Saitoh, H.1    Aungst, B.J.2
  • 53
    • 0030824648 scopus 로고    scopus 로고
    • Carrier-mediated hepatic uptake of quinolone antibiotics in the rat
    • Sasabe H, Terasaki T, Tsuji A and Sugiyama Y (1997) Carrier-mediated hepatic uptake of quinolone antibiotics in the rat. J Pharmacol Exp Ther 282:162-171.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 162-171
    • Sasabe, H.1    Terasaki, T.2    Tsuji, A.3    Sugiyama, Y.4
  • 54
    • 0028103708 scopus 로고
    • Multiple transport systems for organic anions across the bile canalicular membrane
    • Sathirakul K, Suzuki H, Yamada T, Hanano M and Sugiyama Y (1994) Multiple transport systems for organic anions across the bile canalicular membrane. J Pharmacol Exp Ther 268:65-73.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 65-73
    • Sathirakul, K.1    Suzuki, H.2    Yamada, T.3    Hanano, M.4    Sugiyama, Y.5
  • 56
    • 0030059953 scopus 로고    scopus 로고
    • Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
    • Schuetz EG, Beck WT and Schuetz JD (1996) Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol Pharmacol 49:311-318.
    • (1996) Mol Pharmacol , vol.49 , pp. 311-318
    • Schuetz, E.G.1    Beck, W.T.2    Schuetz, J.D.3
  • 57
    • 0028027840 scopus 로고
    • Multiple systems for the biliary excretion of organic anions in rats: Liquiritigenin conjugates as model compounds
    • Shimamura H, Suzuki H, Hanano M, Suzuki A, Tagaya O, Horie T and Sugiyama Y (1994) Multiple systems for the biliary excretion of organic anions in rats: Liquiritigenin conjugates as model compounds. J Pharmacol Exp Ther 271:370-378.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 370-378
    • Shimamura, H.1    Suzuki, H.2    Hanano, M.3    Suzuki, A.4    Tagaya, O.5    Horie, T.6    Sugiyama, Y.7
  • 58
    • 0030444592 scopus 로고    scopus 로고
    • Biliary excretion of glucyrrhizin in rats: Kinetic basis for multiplicity in bile canalicular transport of organic anions
    • Shimamura H, Suzuki H, Tagaya O, Horie T and Sugiyama Y (1996) Biliary excretion of glucyrrhizin in rats: Kinetic basis for multiplicity in bile canalicular transport of organic anions. Pharmaceut Res 13:1833-1837.
    • (1996) Pharmaceut Res , vol.13 , pp. 1833-1837
    • Shimamura, H.1    Suzuki, H.2    Tagaya, O.3    Horie, T.4    Sugiyama, Y.5
  • 59
    • 0001842796 scopus 로고
    • Mechanism-based enzyme inactivation
    • CRC Press, Boca Raton
    • Silverman RB (1988) Mechanism-based enzyme inactivation, in Chemistry and Enzymology, vol 1, pp 3-30, CRC Press, Boca Raton.
    • (1988) Chemistry and Enzymology , vol.1 , pp. 3-30
    • Silverman, R.B.1
  • 60
    • 0026795695 scopus 로고
    • Inhibitors of imipramine metabolism by human liver microsomes
    • Skjelbo E and Brosen K (1992) Inhibitors of imipramine metabolism by human liver microsomes. Br J Clin Pharmacol 34:256-261.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 256-261
    • Skjelbo, E.1    Brosen, K.2
  • 61
    • 0022552455 scopus 로고
    • Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro
    • Slater LM, Sweet P, Stupeckey M and Gupta S (1986) Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro. J Clin Invest 77:1405-1408.
    • (1986) J Clin Invest , vol.77 , pp. 1405-1408
    • Slater, L.M.1    Sweet, P.2    Stupeckey, M.3    Gupta, S.4
  • 62
    • 0023248835 scopus 로고
    • Pharmacokinetic interactions of cimetidine 1987
    • Somogyi A and Muirhead M (1987) Pharmacokinetic interactions of cimetidine 1987. Clin Pharmacokinet 12:321-366.
    • (1987) Clin Pharmacokinet , vol.12 , pp. 321-366
    • Somogyi, A.1    Muirhead, M.2
  • 63
    • 0027432508 scopus 로고
    • Characterization of methotrexate elimination and interaction with indomethacin and flurbiprofen in the isolated perfused rat kidney
    • Statkevich P, Fournier DJ and Sweeney KR (1993) Characterization of methotrexate elimination and interaction with indomethacin and flurbiprofen in the isolated perfused rat kidney. J Pharmacol Exp Ther 265:1118-1124.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1118-1124
    • Statkevich, P.1    Fournier, D.J.2    Sweeney, K.R.3
  • 65
    • 0019847460 scopus 로고
    • Prediction of drug-drug interaction from in vitro plasma protein binding and metabolism
    • Sugita O, Sawada Y, Sugiyama Y, Iga T and Hanano M (1981) Prediction of drug-drug interaction from in vitro plasma protein binding and metabolism. Biochem Pharmacol 30:3347-3354.
    • (1981) Biochem Pharmacol , vol.30 , pp. 3347-3354
    • Sugita, O.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 66
    • 0021341390 scopus 로고
    • Kinetic analysis of tolbutamide-sulfonamide interaction in rabbits based on clearance concept: Prediction of species difference from in vitro plasma protein binding and metabolism
    • Sugita O, Sawada Y, Sugiyama Y, Iga T and Hanano M (1984) Kinetic analysis of tolbutamide-sulfonamide interaction in rabbits based on clearance concept: Prediction of species difference from in vitro plasma protein binding and metabolism. Drug Metab Dispos 12:131-138.
    • (1984) Drug Metab Dispos , vol.12 , pp. 131-138
    • Sugita, O.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 67
    • 0007562143 scopus 로고    scopus 로고
    • Alteration of pharmacokinetic features caused by drug interactions
    • Sugiyama Y and Iwatsubo T (1996) Alteration of pharmacokinetic features caused by drug interactions. Xenobio Metabol Dispos 11:286-293.
    • (1996) Xenobio Metabol Dispos , vol.11 , pp. 286-293
    • Sugiyama, Y.1    Iwatsubo, T.2
  • 68
    • 0030483051 scopus 로고    scopus 로고
    • Strategic proposals for avoiding toxic interactions with drugs for clinical use during development and after marketing of a new drug pharmacokinetic consideration
    • Sugiyama Y, Iwatsubo T, Ueda K and Ito K (1996) Strategic proposals for avoiding toxic interactions with drugs for clinical use during development and after marketing of a new drug pharmacokinetic consideration. J Toxicol Sci 21:309-316.
    • (1996) J Toxicol Sci , vol.21 , pp. 309-316
    • Sugiyama, Y.1    Iwatsubo, T.2    Ueda, K.3    Ito, K.4
  • 69
    • 3142513216 scopus 로고
    • Prediction of pharmacokinetics based on in vitro data
    • Sugiyama Y ed Japanese Society for the Study of Xenobiotics, Tokyo
    • Sugiyama Y and Ooie T (1993) Prediction of pharmacokinetics based on in vitro data, in Methods and Techniques for Pharmacokinetic Studies (Sugiyama Y ed) pp 87-108, Japanese Society for the Study of Xenobiotics, Tokyo.
    • (1993) Methods and Techniques for Pharmacokinetic Studies , pp. 87-108
    • Sugiyama, Y.1    Ooie, T.2
  • 70
    • 0021255131 scopus 로고
    • Carrier-mediated transport systems of tetraethylammonium in rat brush-border and basolateral membrane vesicles
    • Takano M, Inui K, Okano T, Saitoh H and Hori R (1984) Carrier-mediated transport systems of tetraethylammonium in rat brush-border and basolateral membrane vesicles. Biochim Biophys Acta 773:113-124.
    • (1984) Biochim Biophys Acta , vol.773 , pp. 113-124
    • Takano, M.1    Inui, K.2    Okano, T.3    Saitoh, H.4    Hori, R.5
  • 72
    • 0029800447 scopus 로고    scopus 로고
    • Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier
    • Terao T, Hisanaga E, Sai Y, Tamai I and Tsuji A (1996) Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier. J Pharm Pharmacol 48:1083-1089.
    • (1996) J Pharm Pharmacol , vol.48 , pp. 1083-1089
    • Terao, T.1    Hisanaga, E.2    Sai, Y.3    Tamai, I.4    Tsuji, A.5
  • 73
    • 0013926913 scopus 로고
    • The metabolic fate of tolbutamide in man and in the rat
    • Thomas RC and Ikeda GJ (1966) The metabolic fate of tolbutamide in man and in the rat. J Med Chem 9:507-510.
    • (1966) J Med Chem , vol.9 , pp. 507-510
    • Thomas, R.C.1    Ikeda, G.J.2
  • 75
    • 0018678175 scopus 로고
    • Reversible enzyme inhibition
    • Purich DL ed Academic Press, London
    • Todhunter JA (1979) Reversible enzyme inhibition, in Methods in Enzymology (Purich DL ed) vol 63, pp 383-411, Academic Press, London.
    • (1979) Methods in Enzymology , vol.63 , pp. 383-411
    • Todhunter, J.A.1
  • 76
    • 0030004755 scopus 로고    scopus 로고
    • In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors
    • Transon C, Leemann T and Dayer P (1996) In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors. Eur J Clin Pharmacol 50:209-215.
    • (1996) Eur J Clin Pharmacol , vol.50 , pp. 209-215
    • Transon, C.1    Leemann, T.2    Dayer, P.3
  • 77
    • 0019430432 scopus 로고
    • Overcoming of vincristine resistance in P388 leukemia, in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
    • Tsuruo T, lida H, Tsukagoshi S and Sakurai Y (1981) Overcoming of vincristine resistance in P388 leukemia, in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res 41:1967-1972.
    • (1981) Cancer Res , vol.41 , pp. 1967-1972
    • Tsuruo, T.1    Lida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 78
    • 0026677681 scopus 로고
    • The rational selection of drug interaction studies: Implications of recent advances in drug metabolism
    • Tucker GT (1992) The rational selection of drug interaction studies: Implications of recent advances in drug metabolism. Int J Clin Pharmacol Ther Toxicol 30:550-553.
    • (1992) Int J Clin Pharmacol Ther Toxicol , vol.30 , pp. 550-553
    • Tucker, G.T.1
  • 80
    • 0025264682 scopus 로고
    • Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers
    • Veronese ME, Miners JO, Randles D, Gregov D and Birkett DJ (1990) Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers. Clin Pharmacol Ther 47:403-411.
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 403-411
    • Veronese, M.E.1    Miners, J.O.2    Randles, D.3    Gregov, D.4    Birkett, D.J.5
  • 83
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • Wacher VJ, Wu C-Y and Benet LZ (1995) Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy. Mol Careinog 13:129-134.
    • (1995) Mol Careinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.-Y.2    Benet, L.Z.3
  • 85
    • 0021875282 scopus 로고
    • Kinetics of suicide substrates: Practical procedures for determining parameters
    • Waley SG (1985) Kinetics of suicide substrates: Practical procedures for determining parameters. Biochem J 227:843-849.
    • (1985) Biochem J , vol.227 , pp. 843-849
    • Waley, S.G.1
  • 86
    • 0030512057 scopus 로고    scopus 로고
    • Strategic proposals for predicting drug-drug interactions during new drug development: Based on sixteen deaths caused by interactions of the new antiviral sorivudine with 5-fluorouracil prodrugs
    • Watabe T (1996) Strategic proposals for predicting drug-drug interactions during new drug development: Based on sixteen deaths caused by interactions of the new antiviral sorivudine with 5-fluorouracil prodrugs. J Toxicol Sci 21:299-300.
    • (1996) J Toxicol Sci , vol.21 , pp. 299-300
    • Watabe, T.1
  • 87
    • 0020511430 scopus 로고
    • Plasma and tissue binding considerations in drug disposition
    • Wilkinson GR (1983) Plasma and tissue binding considerations in drug disposition. Drug Metab Rev 14:427-465.
    • (1983) Drug Metab Rev , vol.14 , pp. 427-465
    • Wilkinson, G.R.1
  • 88
  • 89
    • 0030909156 scopus 로고    scopus 로고
    • Carriermediated hepatic uptake of the cationic cyclopeptide, octreotide, in rats: Comparison between in vivo and in vitro
    • Yamada T, Niinuma K, Lemaire M, Terasaki T and Sugiyama Y (1997) Carriermediated hepatic uptake of the cationic cyclopeptide, octreotide, in rats: Comparison between in vivo and in vitro. Drug Metab Dispos 25:536-543.
    • (1997) Drug Metab Dispos , vol.25 , pp. 536-543
    • Yamada, T.1    Niinuma, K.2    Lemaire, M.3    Terasaki, T.4    Sugiyama, Y.5
  • 90
    • 0029592262 scopus 로고
    • Kinetic analysis of hepatobiliary transport of drugs: Importance of carrier-mediated transport
    • Yamazaki M, Nishigaki R, Suzuki H and Sugiyama Y (1995) Kinetic analysis of hepatobiliary transport of drugs: Importance of carrier-mediated transport. Yakugaku Zasshi 115:953-977.
    • (1995) Yakugaku Zasshi , vol.115 , pp. 953-977
    • Yamazaki, M.1    Nishigaki, R.2    Suzuki, H.3    Sugiyama, Y.4
  • 92
    • 0029926676 scopus 로고    scopus 로고
    • Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics
    • Yamazaki M, Suzuki H and Sugiyama Y (1996) Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics. Pharmaceut Res 13:497-513.
    • (1996) Pharmaceut Res , vol.13 , pp. 497-513
    • Yamazaki, M.1    Suzuki, H.2    Sugiyama, Y.3
  • 93
    • 0029559885 scopus 로고
    • Effect of omeprazole on diazepam disposition in the rat: In vitro and in vivo studies
    • Zomorodi K and Houston JB (1995) Effect of omeprazole on diazepam disposition in the rat: In vitro and in vivo studies. Pharmaceut Res 12:1642-1646.
    • (1995) Pharmaceut Res , vol.12 , pp. 1642-1646
    • Zomorodi, K.1    Houston, J.B.2


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