-
4
-
-
0001458138
-
Polyoxyäthylenglycerol triricinoleat 35 DAC 1979
-
(1984)
Pharm Zeit
, vol.129
, pp. 1730-1733
-
-
Hoffmann, H.1
-
6
-
-
0002402420
-
Safety profile
-
McGuire WP, Rowinsky EK (eds). Marcel Dekker, New York
-
(1995)
Paclitaxel in Cancer Treatment
, pp. 21-149
-
-
Onetto, N.1
Dougan, M.2
Hellmann, S.3
Gustafson, N.4
Burroughs, J.5
Florczyk, A.6
Canetta, R.7
Rozenweig, M.8
-
9
-
-
0025326680
-
Hypersensitivity reactions from taxol
-
(1990)
J Clin Oncol
, vol.8
, pp. 1263-1268
-
-
Weiss, R.B.1
Donehower, R.C.2
Wiernik, P.H.3
Ohnuma, T.4
Gralla, R.5
Trump, D.L.6
Baker, J.R.7
Van Echo, D.A.8
Von Hoff, D.D.9
Leyland-Jones, B.10
-
11
-
-
0027862694
-
Overview of Taxol safety
-
(1993)
J Natl Cancer Inst Monogr
, vol.15
, pp. 131-139
-
-
Onetto, N.1
Canetta, R.2
Winograd, B.3
Catane, R.4
Dougan, M.5
Grechko, J.6
Burroughs, J.7
Rozencweig, M.8
-
12
-
-
0027999966
-
European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: High-dose versus low-dose and long versus short infusion
-
(1994)
J Clin Oncol
, vol.12
, pp. 2654-2666
-
-
Eisenhauer, E.A.1
Ten Bokkel Huinink, W.W.2
Swenerton, K.D.3
Gianni, L.4
Myles, J.5
Van der Burg, M.E.L.6
Kerr, I.7
Vermorken, J.B.8
Buser, K.9
Colombo, N.10
Bacon, M.11
Santabarbara, P.12
Onetto, N.13
Winograd, B.14
Canetta, R.15
-
17
-
-
0033926580
-
Interrelationships of paclitaxel disposition, infusion duration and Cremophor EL kinetics in cancer patients
-
(2000)
Anti-Cancer Drugs
, vol.11
, pp. 315-324
-
-
Van Zuylen, L.1
Gianni, L.2
Verweij, J.3
Mross, K.4
Brouwer, E.5
Loos, W.J.6
Sparreboom, A.7
-
22
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
(1997)
Proc Natl Acad Sci USA
, vol.4
, pp. 2031-2035
-
-
Sparreboom, A.1
Van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
-
23
-
-
0001583660
-
Coadministration of oral cyclosporin A enables oral therapy with paclitaxel
-
(1999)
Clin Cancer Res
, vol.5
, pp. 3379-3384
-
-
Meerum-Terwogt, J.M.1
Malingré, M.M.2
Beijnen, J.H.3
Ten Bokkel Huinink, W.W.4
Rosing, H.5
Koopman, F.J.6
Van Tellingen, O.7
Swart, M.8
Schellens, J.H.M.9
-
35
-
-
0028914767
-
Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability
-
(1995)
Eur J Biochem
, vol.228
, pp. 1020-1029
-
-
Drori, S.1
Eytan, G.D.2
Assaraf, Y.G.3
-
39
-
-
0032144286
-
Linearized colorimetric assay for Cremophor EL: Application to pharmacokinetics after 1-hour paclitaxel infusions
-
(1998)
Anal Biochem
, vol.261
, pp. 198-202
-
-
Brouwer, E.1
Verweij, J.2
Hauns, B.3
Loos, W.J.4
Nooter, K.5
Mross, K.6
Stoter, G.7
Sparreboom, A.8
-
42
-
-
0032418707
-
Quantitative determination of polysorbate 20 in nasal pharmaceutical preparations by high-performance liquid chromatography
-
(1998)
J Pharm Biomed Anal
, vol.18
, pp. 715-720
-
-
Oszi, Z.1
Petho, G.2
-
48
-
-
0033670057
-
Cremophor EL pharmacokinetics in a Phase I study of paclitaxel (Taxol) and carboplatin in non-small cell lung cancer patients
-
(2000)
Anticancer Drugs
, vol.11
, pp. 687-694
-
-
Meerum Terwogt, J.M.1
Van Tellingen, O.2
Nannan Panday, V.R.3
Huizing, M.T.4
Schellens, J.H.M.5
Ten Bokkel Huinink, W.W.6
Boschma, M.U.S.7
Giaccone, G.8
Veenhof, C.H.N.9
Beijnen, J.H.10
-
49
-
-
0029740954
-
Cremophor pharmacokinetics in patients receiving 3-, 6-, and 24-hour infusions of paclitaxel
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1297-1301
-
-
Rischin, D.1
Webster, L.K.2
Millward, M.J.3
Linahan, B.M.4
Toner, G.C.5
Woollett, A.M.6
Morton, C.G.7
Bishop, J.F.8
-
50
-
-
0031872770
-
Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1937-1942
-
-
Sparreboom, A.1
Verweij, J.2
Van der Burg, M.E.L.3
Loos, W.J.4
Brouwer, E.5
Viganó, L.6
Locatelli, A.7
De Vos, A.I.8
Nooter, K.9
Stoter, G.10
Gianni, L.11
-
51
-
-
0004312878
-
Pharmacologic study of Cremophor EL in cancer patients with impaired hepatic function receiving taxol
-
Academic Thesis, Utrecht University
-
(1999)
Clinical Pharmacology of Paclitaxel and Platinum Compounds
, pp. 109-120
-
-
Nannan Panday, V.R.1
Huizing, M.T.2
Van Tellingen, O.3
Hakvoort, R.A.4
Willemse, P.H.B.5
De Graeff, A.6
Vermorken, J.B.7
Beijnen, J.H.8
-
52
-
-
0032734467
-
3H] paclitaxel and Cremophor EL in a patient severely impaired renal function
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 1300-1305
-
-
Gelderblom, H.1
Verweij, J.2
Brouwer, E.3
Pillay, M.4
De Bruijn, P.5
Nooter, K.6
Stoter, G.7
Sparreboom, A.8
-
54
-
-
0004927826
-
Intermediary metabolism of certain polyoxyethylene derivatives in man. I. Recovery of the polyoxyethylene moiety from urine and feces following ingestion of polyoxyethylene (20) sorbitan monooletate and of polyoxyethylene (40) monostearate
-
(1951)
J Pharmacol Exp Ther
, vol.103
, pp. 377-381
-
-
Culver, P.J.1
Wilcox, C.S.2
Jones, C.M.3
Ross, R.S.4
-
60
-
-
0033118955
-
Cremophor EL-mediated alteration of paclitaxel distribution in human blood: Clinical pharmacokinetic implications
-
(1999)
Cancer Res
, vol.59
, pp. 1454-1457
-
-
Sparreboom, A.1
Van Zuyien, L.2
Brouwer, E.3
Loos, W.J.4
De Bruijn, P.5
Gelderblom, H.6
Pillay, M.7
Nooter, K.8
Stoter, G.9
Verweij, J.10
-
66
-
-
0028894301
-
Nonlinear pharmcokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans
-
(1995)
J Clin Oncol
, vol.13
, pp. 180-190
-
-
Gianni, L.1
Kearns, C.M.2
Giani, A.3
Capri, G.4
Vigano, L.5
Locatelli, A.6
Bonadonna, G.7
Egorin, M.J.8
-
75
-
-
0031723119
-
Phase I trial of Cremophor EL with bolus doxorubicin
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2321-2329
-
-
Millward, M.J.1
Webster, L.K.2
Rischin, D.3
Stokes, K.H.4
Toner, G.C.5
Bishop, J.I.F.6
Olver, I.N.7
Linahan, B.M.8
Linsenmeyer, M.E.9
Woodcock, D.M.10
-
77
-
-
10144261886
-
Sequence-dependent alteration of doxorubicin pharmacokinetics by paclitaxel in a Phase I study of paclitaxel and doxorubicin in patients with metastatic breast cancer
-
(1996)
J Clin Oncol
, vol.14
, pp. 2713-2721
-
-
Holmes, F.A.1
Madden, T.2
Newman, R.A.3
Valero, V.4
Theriault, R.L.5
Fraschini, G.6
Walters, R.S.7
Booser, D.J.8
Buzdar, A.U.9
Willey, J.10
Hortobagyi, G.N.11
-
78
-
-
0032978855
-
A Phase I study of continuous infusion doxorubicin and paclitaxel chemotherapy with granulocyte colony-stimulating factor for relapsed epithelial ovarian cancer
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1299-1305
-
-
Duska, L.R.1
Penson, R.2
Supko, J.G.3
Finkelstein, D.M.4
Makastorsis, T.5
Gallagher, J.6
Borden, K.7
Goodman, A.8
Fuller, A.F.9
Nikrui, N.10
Seiden, M.V.11
-
81
-
-
0022885034
-
Role of the carrier solution in cyclosporine phannacokinetics in the baboon
-
(1986)
J Heart Transplant
, vol.5
, pp. 312-316
-
-
Kurlansky, P.A.1
Sadeghi, A.M.2
Michler, R.E.3
Coppey, L.J.4
Re, L.P.5
Thomas, W.G.6
Smith, C.R.7
Reemtsma, K.8
Rose, E.A.9
-
85
-
-
0000590536
-
Docetaxel in combination with doxorubicin as first line chemotherapy of metastatic breast cancer: A Phase I dose finding study
-
(1996)
Proc Am Assoc Clin Oncol
, vol.15
, pp. 148
-
-
Bourgeois, H.1
Gruia, G.2
Dieras, V.3
Kalla, S.4
Giaccetti, S.5
Cvitkovic, E.6
Aussel, J.P.7
Azli, N.8
Riva, A.9
Poullart, P.10
Misser, J.L.11
-
87
-
-
0032937810
-
Comparative effects of paclitaxel and docetaxel on the metabolism and pharmacokinetic of epirubicin in breast cancer patients
-
(1999)
J Clin Oncol
, vol.17
, pp. 1132-1138
-
-
Eposito, M.1
Venturini, M.2
Vannozzi, M.O.3
Tolino, G.4
Lunardi, G.5
Garrone, O.6
Angiolini, C.7
Viale, M.8
Bergaglio, M.9
Del Mastro, L.10
Rosso, R.11
-
90
-
-
0019506405
-
Effect of polysorbate 80 on the apparent partition coefficient of drugs on their intestinal absorption in the rat: II. Phenobarbital
-
(1981)
Int J Pharm
, vol.7
, pp. 205-210
-
-
Hikal, A.H.1
-
92
-
-
0025020496
-
Thiotepa pharmacokinefics during intravesical chemotherapy and the influence of Tween 80
-
(1990)
Cancer Chemother Pharmacol
, vol.25
, pp. 267-273
-
-
Masters, J.R.1
McDermott, B.J.2
Jenkins, W.E.3
Fenwick, E.4
Shah, P.J.5
Mundy, A.R.6
Loadman, P.M.7
Bibby, M.C.8
-
93
-
-
0025325040
-
Reversal of the multidrug resistance phenotype with Cremophor EL, a common vehicle for water-insoluble vitamins and drugs
-
(1990)
Cancer Res
, vol.50
, pp. 4199-4203
-
-
Woodcock, D.M.1
Jefferson, S.2
Linsenmeyer, M.E.3
Crowther, P.J.4
Chojnowski, G.M.5
Williams, B.6
Bertoncello, I.7
-
96
-
-
0025133137
-
The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance
-
(1990)
Br J Cancer
, vol.62
, pp. 591-594
-
-
Schuurhuis, G.J.1
Broxterman, H.J.2
Pinedo, H.M.3
Van Heijningen, T.H.M.4
Van Kalker, C.K.5
Vermorken, J.B.6
Spoelstra, E.C.7
Lankelma, J.8
-
106
-
-
0028047339
-
Synergistic reversal of multidrug-resistance phenotype in acute myeloid leukemia cells by cyclosporin A and Cremophor EL
-
(1995)
Blood
, vol.83
, pp. 1337-1347
-
-
Ross, D.D.1
Wooten, P.J.2
Tong, Y.3
Comblatt, B.4
Levy, C.5
Sridhara, R.6
Lee, E.J.7
Schiffer, C.A.8
-
115
-
-
0027494879
-
Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients
-
(1993)
J Clin Oncol
, vol.11
, pp. 2127-2135
-
-
Huizing, M.T.1
Keung, A.C.2
Rosing, H.3
Van der Kuij, V.4
Ten Bokkel Huinink, W.W.5
Mandjes, I.M.6
Dubbelman, A.C.7
Pinedo, H.M.8
Beijnen, J.R.9
-
118
-
-
0028934665
-
The cytotoxic activity of Taxol in primary cultures of tumour cells from patients is partly mediated by Cremophor EL
-
(1995)
Br J Cancer
, vol.71
, pp. 478-481
-
-
Nygren, P.1
Csóka, K.2
Jonsson, B.3
Fridborg, H.4
Bergh, J.5
Hagberg, H.6
Glimelius, B.7
Brodin, O.8
Tholander, B.9
Kreuger, A.10
Lönnerholm, G.11
Jakobsson, Å.12
Olsen, L.13
Kristensen, J.14
Larsson, R.15
-
120
-
-
0028139542
-
Paclitaxel induced cytotoxicity - The effects of cremophor EL (castor oil) on two human breast cancer cell lines with acquired multidrug resistant phenotype and induced expression of the permeability glycoprotein
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 687-690
-
-
Fjällskog, M.L.1
Frii, L.2
Bergh, J.3
-
123
-
-
0030918258
-
Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro
-
(1997)
Br J Cancer
, vol.75
, pp. 1744-1752
-
-
Terzis, A.J.1
Thorsen, F.2
Heese, O.3
Visted, T.4
Bjerkvig, R.5
Dahl, O.6
Arnold, H.7
Gundersen, G.8
-
128
-
-
0028224041
-
Study for modifying activity of solvents on antitumor activity of paclitaxel
-
Japanese
-
(1994)
Gan To Kagaku Ryoho
, vol.21
, pp. 665-670
-
-
Fujimoto, S.1
-
132
-
-
0028877036
-
Paclitaxel by 3-hour infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: High antitumor efficacy and cardiac effects in a dose-finding and sequence-finding study
-
(1995)
J Clin Oncol
, vol.13
, pp. 2688-2699
-
-
Gianni, L.1
Munzone, E.2
Capri, A.3
Fulfaro, F.4
Tarenzi, E.5
Villani, F.6
Spreafico, C.7
Laffranchi, A.8
Caraceni, A.9
Martini, C.10
Stefanelli, M.11
Valagussa, P.12
Bonadonna, G.13
-
135
-
-
0028806664
-
Doxorubicin/paclitaxel combination chemotherapy for metastatic breast cancer: The Eastern Cooperative Oncology Group experience
-
(1995)
Semin Oncol
, vol.22
, pp. 123-125
-
-
Sledge, G.W.1
-
136
-
-
0025850566
-
Sequences of taxol and cisplatin: A Phase I and pharmacologic study
-
(1991)
J Clin Oncol
, vol.9
, pp. 1692-1703
-
-
Rowinsky, E.K.1
Gilbert, M.R.2
McGuire, W.P.3
Noe, D.A.4
Grochow, L.B.5
Forastiere, A.A.6
Clark, B.7
Sartorius, S.E.8
Cornblath, D.R.9
Hendricks, C.B.10
Donehower, R.C.11
-
137
-
-
0031044607
-
Phase I and pharmacologic study of docetaxel and cisplatin in patients with advanced solid tumors
-
(1997)
J Clin Oncol
, vol.15
, pp. 1071-1079
-
-
Pronk, L.C.1
Schellens, J.H.M.2
Planting, A.S.T.3
Van den Bent, M.J.4
Hilkens, P.H.5
Van der Burg, M.E.L.6
De Boer-Dennert, M.7
Ma, J.8
Blanc, C.9
Harteveld, M.10
Bruno, R.11
Stoter, G.12
Verweij, J.13
-
138
-
-
0001574133
-
Pharmacokinetics of cisplatin and Taxotere (docetaxel) and PBL DNA-adduct formation of cisplatin in the sequence Taxotere/cisplatin and cisplatin/Taxotere in a Phase I/II study in solid tumor patients
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 132
-
-
Schellens, J.H.M.1
Ma, J.2
Bruno, R.3
Paccaly, D.4
Vergniol, J.C.5
Planting, A.S.T.6
De Boer-Dennert, M.7
Van der Burg, M.E.L.8
Stoter, G.9
Verweij, J.10
-
139
-
-
0028901405
-
Current sample handling methods for measurement of cisplatin-DNA-adducts in leukocytes in man lead to discrepant results in DNA-adduct levels and DNA-repair
-
(1995)
Br J Cancer
, vol.71
, pp. 512-517
-
-
Ma, J.1
Verweij, J.2
Planting, A.S.T.3
De Boer-Dennert, M.4
Van Ingen, H.E.5
Van der Burg, M.E.L.6
Stoter, G.7
Schellens, J.H.M.8
-
140
-
-
9844220294
-
Differential modulation of cisplatin accumulation in leukocytes and tumor cell lines by the paclitaxel vehicle Cremophor EL
-
(1997)
Ann Oncol
, vol.8
, pp. 1145-1150
-
-
De Vos, A.I.1
Nooter, K.2
Verweij, J.3
Loos, W.J.4
Brouwer, E.5
De Bruijn, P.6
Ruijgrok, E.J.7
Van der Burg, M.E.L.8
Stoter, G.9
Sparreboom, A.10
-
144
-
-
0031047886
-
Clinical pharmacology of carboplatin administered in combination with paclitaxel
-
(1997)
Semin Oncol
, vol.24
, Issue.SUPPL. 2
, pp. 97-104
-
-
Van Warmerdam, L.C.J.1
Huizing, M.T.2
Giaccone, G.3
Postmus, P.E.4
Ten Bokkel Huinink, W.W.5
Van Zandwijk, N.6
Koolen, M.G.7
Helmerhorst, T.J.8
Van der Vijgh, W.J.9
Veenhof, C.H.10
Beijnen, J.H.11
-
145
-
-
0000397829
-
Randomised, crossover trial to determine the effect of cremophor on the pharmacokinetics and pharmacodynamics or carboplatin-based therapy
-
(1998)
Ann Oncol
, vol.9
, Issue.SUPPL. 2
, pp. 130
-
-
Millward, M.J.1
Webster, L.K.2
Rischin, D.3
Ellis, A.G.4
Linahan, B.M.5
Maisano, R.6
Toner, G.C.7
Stokes, K.H.8
-
146
-
-
0029976216
-
Phase I and pharmacologic study of sequences of paclitaxel and cyclo-phosphamide supported by granulocyte colony-stimulating factor in women with previously treated metastatic breast cancer
-
(1996)
J Clin Oncol
, vol.14
, pp. 783-791
-
-
Kennedy, M.J.1
Zahurak, M.L.2
Donehower, R.3
Noe, D.A.4
Sartorius, S.5
Chen, T.L.6
Bowling, K.7
Rowinsky, E.K.8
-
147
-
-
0031938204
-
Sequence-dependent hematological toxicity associated with 3-hour paclitaxel/cyclophosphamide doublet
-
(1998)
Clin Cancer Res
, vol.4
, pp. 349-356
-
-
Kennedy, M.J.1
Zahurak, M.L.2
Donehower, R.C.3
Noe, D.A.4
Grochow, L.B.5
Sartofius, S.6
Chen, T.L.7
Bowling, K.8
Duerr, M.9
Rowinsky, E.K.10
-
148
-
-
9044235183
-
Phase I study of paclitaxel in combination with cyclophosphamide and granulocyte colony-stimulating factor in metastatic breast cancer patients
-
(1996)
J Clin Oncol
, vol.14
, pp. 95-102
-
-
Tolcher, A.W.1
Cowan, K.H.2
Noone, M.H.3
Denicoff, A.M.4
Kohler, D.R.5
Goldspiel, B.R.6
Barnes, C.S.7
McCabe, M.8
Gossard, M.R.9
Zulewski, J.10
O'Shaughnessy, J.A.11
-
149
-
-
0003267585
-
Phase I study of Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel (Abi-007) in solid tumors
-
(2000)
Proc Am Assoc Clin Oncol
, vol.18
-
-
Ibrahim, N.K.1
Ellerhorst, J.A.2
Theriault, R.L.3
Rivera, E.4
Esmaeli, B.5
Legha, S.S.6
Ring, S.E.7
Soon-Shiong, P.8
Benjamin, R.S.9
Hortobagyi, G.N.10
-
150
-
-
0004935950
-
A dose finding and pharmacokinetic (PK) Phase I study of a new formulation of docetaxel (D) in advanced solid tumors
-
(1998)
Ann Oncol
, vol.9
, Issue.SUPPL. 2
, pp. 101
-
-
Fumoleau, P.1
Tubiana-Hulin, M.2
Soulié, P.3
Delecroix, V.4
Sistac, F.5
Mefti, F.6
Soulas, F.7
Appia, E.8
Lebecq, A.9
Vergniol, J.C.10
Vernillet, L.11
Riva, A.12
|