The P-glycoprotein efflux pump: How does it transport drugs?

Journal of Membrane Biology

Volumn 160, Issue 3, 1997, Pages 161-175

  Sharom, F J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

ABC superfamily; ATPase; Chemotherapy drugs; Flippase; Membrane transport; Multidrug resistance

Indexed keywords

ALDOSTERONE; AMIODARONE; ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CALMODULIN INHIBITOR; CHLOROQUINE; CHLORPROMAZINE; CHYMOSTATIN; COLCHICINE; CYCLOSPORIN A; DACTINOMYCIN; DAUNORUBICIN; DIPYRIDAMOLE; DOCETAXEL; DOXORUBICIN; EPIPODOPHYLLOTOXIN; GLYCOPROTEIN P; MITOXANTRONE; NIFEDIPINE; TACROLIMUS; TAMOXIFEN; TERFENADINE; TRIFLUOPERAZINE; UNINDEXED DRUG; VALINOMYCIN; VALSPODAR; VERAPAMIL; VINBLASTINE; VINCRISTINE;

CONFORMATIONAL TRANSITION; CROSS RESISTANCE; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENZYME ACTIVITY; HUMAN; HYDROLYSIS; MEMBRANE VESICLE; MULTIDRUG RESISTANCE; NONHUMAN; REVIEW;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; DRUG RESISTANCE, MULTIPLE; HUMANS; ION TRANSPORT; P-GLYCOPROTEIN;

EID: 0031455482     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900305     Document Type: Review

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