-
1
-
-
0036453721
-
Evolution of the TIR, tolls and TLRs: Functional inferences from computational biology
-
Beutler B, Rehli M. Evolution of the TIR, tolls and TLRs: functional inferences from computational biology. Curr Top Microbiol Immunol 2002; 270:1-21.
-
(2002)
Curr Top Microbiol Immunol
, vol.270
, pp. 1-21
-
-
Beutler, B.1
Rehli, M.2
-
2
-
-
0035859020
-
Plant pathogens and integrated defence responses to infection
-
Dangl JL, Jones JD. Plant pathogens and integrated defence responses to infection. Nature 2001; 411:826-33.
-
(2001)
Nature
, vol.411
, pp. 826-833
-
-
Dangl, J.L.1
Jones, J.D.2
-
3
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996; 86:973-83.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
4
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388:394-7.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr, C.A.3
-
5
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282:2085-8.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
6
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
Qureshi ST, Lariviere L, Leveque G et al. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J Exp Med 1999; 189:615-25.
-
(1999)
J Exp Med
, vol.189
, pp. 615-625
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
-
7
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product
-
Hoshino K, Takeuchi O, Kawai T et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 1999; 162:3749-52.
-
(1999)
J Immunol
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
-
8
-
-
0037290876
-
Mammalian Toll-like receptors
-
Akira S. Mammalian Toll-like receptors. Curr Opin Immunol 2003; 15:5-11.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 5-11
-
-
Akira, S.1
-
9
-
-
1542377424
-
A Toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang D, Zhang G, Hayden MS et al. A Toll-like receptor that prevents infection by uropathogenic bacteria. Science 2004; 303:1522-6.
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
-
10
-
-
4344627821
-
Endogenous ligands of Toll-like receptors
-
Tsan MF, Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol 2004; 76:514-19.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 514-519
-
-
Tsan, M.F.1
Gao, B.2
-
11
-
-
29444441343
-
Manifold mechanisms of Toll-like receptor-ligand recognition
-
Ishii KJ, Coban C, Akira S. Manifold mechanisms of Toll-like receptor-ligand recognition. J Clin Immunol 2005; 25:511-21.
-
(2005)
J Clin Immunol
, vol.25
, pp. 511-521
-
-
Ishii, K.J.1
Coban, C.2
Akira, S.3
-
12
-
-
23344431978
-
The molecular structure of the Toll-like receptor 3 ligand-binding domain
-
Bell JK, Botos I, Hall PR et al. The molecular structure of the Toll-like receptor 3 ligand-binding domain. Proc Natl Acad Sci USA 2005; 102:10976-80.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10976-10980
-
-
Bell, J.K.1
Botos, I.2
Hall, P.R.3
-
13
-
-
23044445303
-
Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain
-
Choe J, Kelker MS, Wilson IA. Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain. Science 2005; 309:581-5.
-
(2005)
Science
, vol.309
, pp. 581-585
-
-
Choe, J.1
Kelker, M.S.2
Wilson, I.A.3
-
14
-
-
33745048928
-
The dsRNA binding site of human Toll-like receptor 3
-
Bell JK, Askins J, Hall PR, Davies DR, Segal DM. The dsRNA binding site of human Toll-like receptor 3 Proc Natl Acad Sci USA 2006; 103:8792-7.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8792-8797
-
-
Bell, J.K.1
Askins, J.2
Hall, P.R.3
Davies, D.R.4
Segal, D.M.5
-
15
-
-
0041467711
-
Toll-like receptors: Networking for success
-
Underhill DM. Toll-like receptors: networking for success. Eur J Immunol 2003; 33:1767-75.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1767-1775
-
-
Underhill, D.M.1
-
16
-
-
3242758082
-
Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses
-
Triantafilou M, Brandenburg K, Kusumoto S et al. Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses. Biochem J 2004; 381:527-36.
-
(2004)
Biochem J
, vol.381
, pp. 527-536
-
-
Triantafilou, M.1
Brandenburg, K.2
Kusumoto, S.3
-
17
-
-
33746253323
-
Dirty little secrets' - endotoxin contamination of recombinant proteins
-
Wakelin SJ, Sabroe I, Gregory CD et al. 'Dirty little secrets' - endotoxin contamination of recombinant proteins. Immunol Lett 2006; 106:1-7.
-
(2006)
Immunol Lett
, vol.106
, pp. 1-7
-
-
Wakelin, S.J.1
Sabroe, I.2
Gregory, C.D.3
-
18
-
-
1342324587
-
Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense
-
Knapp S, Wieland CW, van't Veer C et al. Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense. J Immunol 2004; 172:3132-8.
-
(2004)
J Immunol
, vol.172
, pp. 3132-3138
-
-
Knapp, S.1
Wieland, C.W.2
van't Veer, C.3
-
19
-
-
0035500281
-
Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli
-
Martin M, Katz J, Vogel SN, Michalek SM. Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli. J Immunol 2001; 167:5278-85.
-
(2001)
J Immunol
, vol.167
, pp. 5278-5285
-
-
Martin, M.1
Katz, J.2
Vogel, S.N.3
Michalek, S.M.4
-
20
-
-
0038448227
-
Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling
-
Tapping RI, Tobias PS. Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling. J Endotoxin Res 2003; 9:264-8.
-
(2003)
J Endotoxin Res
, vol.9
, pp. 264-268
-
-
Tapping, R.I.1
Tobias, P.S.2
-
21
-
-
20044368019
-
Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88
-
Hasan U, Chaffois C, Gaillard C et al. Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J Immunol 2005; 174:2942-50.
-
(2005)
J Immunol
, vol.174
, pp. 2942-2950
-
-
Hasan, U.1
Chaffois, C.2
Gaillard, C.3
-
22
-
-
0036232737
-
Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells
-
Spitzer JH, Visintin A, Mazzoni A, Kennedy MN, Segal DM. Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells. Eur J Immunol 2002; 32:1182-7.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1182-1187
-
-
Spitzer, J.H.1
Visintin, A.2
Mazzoni, A.3
Kennedy, M.N.4
Segal, D.M.5
-
23
-
-
0037604765
-
Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes
-
Mizel SB, Honko AN, Moors MA, Smith PS, West AP. Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes. J Immunol 2003; 170:6217-23.
-
(2003)
J Immunol
, vol.170
, pp. 6217-6223
-
-
Mizel, S.B.1
Honko, A.N.2
Moors, M.A.3
Smith, P.S.4
West, A.P.5
-
24
-
-
0035173628
-
CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression
-
Perera PY, Mayadas TN, Takeuchi O et al. CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression. J Immunol 2001; 166:574-81.
-
(2001)
J Immunol
, vol.166
, pp. 574-581
-
-
Perera, P.Y.1
Mayadas, T.N.2
Takeuchi, O.3
-
25
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones EA, Popova L, Kwinn L et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000; 1:398-401.
-
(2000)
Nat Immunol
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
-
26
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with Toll-like receptor 4
-
Rassa JC, Meyers JL, Zhang Y, Kudaravalli R, Ross SR. Murine retroviruses activate B cells via interaction with Toll-like receptor 4. Proc Natl Acad Sci USA 2002; 99:2281-6.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2281-2286
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.3
Kudaravalli, R.4
Ross, S.R.5
-
27
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F, Smith KD, Ozinsky A et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001; 410:1099-103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
-
28
-
-
0347776208
-
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
-
Smith KD, Andersen-Nissen E, Hayashi F et al. Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility. Nat Immunol 2003; 4:1247-53.
-
(2003)
Nat Immunol
, vol.4
, pp. 1247-1253
-
-
Smith, K.D.1
Andersen-Nissen, E.2
Hayashi, F.3
-
29
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001; 413:732-8.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
30
-
-
0242391997
-
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
-
Heil F, Ahmad-Nejad P, Hemmi H et al. The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 2003; 33:2987-97.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2987-2997
-
-
Heil, F.1
Ahmad-Nejad, P.2
Hemmi, H.3
-
31
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004; 303:1529-31.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis5
Sousa, C.6
-
32
-
-
0036456708
-
Imiquimod and the imidazoquinolones: Mechanism of action and therapeutic potential
-
Stanley MA. Imiquimod and the imidazoquinolones: mechanism of action and therapeutic potential. Clin Exp Dermatol 2002; 27:571-7.
-
(2002)
Clin Exp Dermatol
, vol.27
, pp. 571-577
-
-
Stanley, M.A.1
-
33
-
-
21844442818
-
Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimod
-
Spaner DE, Miller RL, Mena J, Grossman L, Sorrenti V, Shi Y. Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimod. Leuk Lymph 2005; 46:935-9.
-
(2005)
Leuk Lymph
, vol.46
, pp. 935-939
-
-
Spaner, D.E.1
Miller, R.L.2
Mena, J.3
Grossman, L.4
Sorrenti, V.5
Shi, Y.6
-
34
-
-
0842328805
-
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9
-
Krug A, Luker GD, Barchet W, Leib DA, Akira S, Colonna M. Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9. Blood 2004; 103:1433-7.
-
(2004)
Blood
, vol.103
, pp. 1433-1437
-
-
Krug, A.1
Luker, G.D.2
Barchet, W.3
Leib, D.A.4
Akira, S.5
Colonna, M.6
-
35
-
-
0042123694
-
Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells
-
Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med 2003; 198:513-20.
-
(2003)
J Exp Med
, vol.198
, pp. 513-520
-
-
Lund, J.1
Sato, A.2
Akira, S.3
Medzhitov, R.4
Iwasaki, A.5
-
36
-
-
0036076593
-
Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling
-
Matsumoto M, Kikkawa S, Kohase M, Miyake K, Seya T. Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. Biochem Biophys Res Commun 2002; 293:1364-9.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 1364-1369
-
-
Matsumoto, M.1
Kikkawa, S.2
Kohase, M.3
Miyake, K.4
Seya, T.5
-
37
-
-
0041331693
-
Subcellular localization of Toll-like receptor 3 in human dendritic cells
-
Matsumoto M, Funami K, Tanabe M et al. Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol 2003; 171:3154-62.
-
(2003)
J Immunol
, vol.171
, pp. 3154-3162
-
-
Matsumoto, M.1
Funami, K.2
Tanabe, M.3
-
38
-
-
4444292595
-
Activation of airway epithelial cells by toll-like receptor agonists
-
Sha Q, Truong-Tran AQ, Plitt JR, Beck LA, Schleimer RP. Activation of airway epithelial cells by toll-like receptor agonists. Am J Respir Cell Mol Biol 2004; 31:358-64.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 358-364
-
-
Sha, Q.1
Truong-Tran, A.Q.2
Plitt, J.R.3
Beck, L.A.4
Schleimer, R.P.5
-
39
-
-
33845655896
-
Cooperative molecular and cellular networks regulate TLR-dependent inflammatory responses
-
in press
-
Morris GE, Parker LC, Ward JR et al. Cooperative molecular and cellular networks regulate TLR-dependent inflammatory responses. FASEB J in press.
-
FASEB J
-
-
Morris, G.E.1
Parker, L.C.2
Ward, J.R.3
-
40
-
-
0036216769
-
Phagocytosis of microbes: Complexity in action
-
Underhill DM, Ozinsky A. Phagocytosis of microbes: complexity in action. Annu Rev Immunol 2002 2006; 20:825-52.
-
(2002)
Annu Rev Immunol
, vol.2006
, Issue.20
, pp. 825-852
-
-
Underhill, D.M.1
Ozinsky, A.2
-
41
-
-
0033592748
-
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
-
Underhill DM, Ozinsky A, Hajjar AM et al. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999; 401:811-15.
-
(1999)
Nature
, vol.401
, pp. 811-815
-
-
Underhill, D.M.1
Ozinsky, A.2
Hajjar, A.M.3
-
42
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
-
Ozinsky A, Underhill DM, Fontenot JD et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc Natl Acad Sci USA 2000; 97:13766-71.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
-
43
-
-
1842477469
-
mRNA is an endogenous ligand for Toll-like receptor 3
-
Kariko K, Ni H, Capodici J, Lamphier M, Weissman D. mRNA is an endogenous ligand for Toll-like receptor 3. J Biol Chem 2004; 279:12542-50.
-
(2004)
J Biol Chem
, vol.279
, pp. 12542-12550
-
-
Kariko, K.1
Ni, H.2
Capodici, J.3
Lamphier, M.4
Weissman, D.5
-
44
-
-
0036829687
-
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2
-
Biragyn A, Ruffini PA, Leifer CA et al. Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science 2002; 298:1025-9.
-
(2002)
Science
, vol.298
, pp. 1025-1029
-
-
Biragyn, A.1
Ruffini, P.A.2
Leifer, C.A.3
-
45
-
-
0035895913
-
Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes
-
Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem 2001; 276:5197-203.
-
(2001)
J Biol Chem
, vol.276
, pp. 5197-5203
-
-
Frantz, S.1
Kelly, R.A.2
Bourcier, T.3
-
46
-
-
33646882893
-
Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis
-
Roelofs MF, Boelens WC, Joosten LA et al. Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis. J Immunol 2006; 176:7021-7.
-
(2006)
J Immunol
, vol.176
, pp. 7021-7027
-
-
Roelofs, M.F.1
Boelens, W.C.2
Joosten, L.A.3
-
47
-
-
0035451118
-
Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4
-
Smiley ST, King JA, Hancock WW. Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J Immunol 2001; 167:2887-94.
-
(2001)
J Immunol
, vol.167
, pp. 2887-2894
-
-
Smiley, S.T.1
King, J.A.2
Hancock, W.W.3
-
48
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot L, Balloy V, McCormack FX, Golenbock DT, Chignard M, Si-Tahar M. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J Immunol 2002; 168:5989-92.
-
(2002)
J Immunol
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
Si-Tahar, M.6
-
49
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura Y, Watari M, Jerud ES et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001; 276:10229-33.
-
(2001)
J Biol Chem
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
-
50
-
-
0037094084
-
Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
-
Johnson GB, Brunn GJ, Kodaira Y, Platt JL. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol 2002; 168:5233-9.
-
(2002)
J Immunol
, vol.168
, pp. 5233-5239
-
-
Johnson, G.B.1
Brunn, G.J.2
Kodaira, Y.3
Platt, J.L.4
-
51
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park JS, Svetkauskaite D, He Q et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004; 279:7370-7.
-
(2004)
J Biol Chem
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
-
52
-
-
30044442866
-
How Toll-like receptors signal: What we know and what we don't know
-
O'Neill LA. How Toll-like receptors signal: what we know and what we don't know. Curr Opin Immunol 2006; 18:3-9.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 3-9
-
-
O'Neill, L.A.1
-
54
-
-
23744454577
-
TLR signalling and activation of IRFs: Revisiting old friends from the NF-kappaB pathway
-
Moynagh PN. TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway. Trends Immunol 2005; 26:469-76.
-
(2005)
Trends Immunol
, vol.26
, pp. 469-476
-
-
Moynagh, P.N.1
-
55
-
-
0037505362
-
The Toll-IL-1 receptor adaptor family grows to five members
-
O'Neill LA, Fitzgerald KA, Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends Immunol 2003; 24:286-90.
-
(2003)
Trends Immunol
, vol.24
, pp. 286-290
-
-
O'Neill, L.A.1
Fitzgerald, K.A.2
Bowie, A.G.3
-
56
-
-
0033583034
-
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
-
Zhang FX, Kirschning CJ, Mancinelli R et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem 1999; 274:7611-14.
-
(1999)
J Biol Chem
, vol.274
, pp. 7611-7614
-
-
Zhang, F.X.1
Kirschning, C.J.2
Mancinelli, R.3
-
57
-
-
0343114462
-
Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
-
Hacker H, Mischak H, Hacker G et al. Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells. EMBO J 1999; 18:6973-82.
-
(1999)
EMBO J
, vol.18
, pp. 6973-6982
-
-
Hacker, H.1
Mischak, H.2
Hacker, G.3
-
58
-
-
0034650930
-
Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors
-
Cario E, Rosenberg IM, Brandwein SL, Beck PL, Reinecker HC, Podolsky DK. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J Immunol 2000; 164:966-72.
-
(2000)
J Immunol
, vol.164
, pp. 966-972
-
-
Cario, E.1
Rosenberg, I.M.2
Brandwein, S.L.3
Beck, P.L.4
Reinecker, H.C.5
Podolsky, D.K.6
-
59
-
-
0035284834
-
Requirement of mitogen-activated protein kinases and I kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide
-
Ropert C, Almeida IC, Closel M et al. Requirement of mitogen-activated protein kinases and I kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide. J Immunol 2001; 166:3423-31.
-
(2001)
J Immunol
, vol.166
, pp. 3423-3431
-
-
Ropert, C.1
Almeida, I.C.2
Closel, M.3
-
60
-
-
1642483742
-
Lipopolysaccharide- induced c-Jun NH2-terminal kinase activation in human neutrophils: Role of phosphatidylinositol 3-kinase and Syk-mediated pathways
-
Arndt PG, Suzuki N, Avdi NJ, Malcolm KC, Worthen GS. Lipopolysaccharide- induced c-Jun NH2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-kinase and Syk-mediated pathways. J Biol Chem 2004; 279:10883-91.
-
(2004)
J Biol Chem
, vol.279
, pp. 10883-10891
-
-
Arndt, P.G.1
Suzuki, N.2
Avdi, N.J.3
Malcolm, K.C.4
Worthen, G.S.5
-
61
-
-
2142652249
-
Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils
-
Strassheim D, Asehnoune K, Park JS et al. Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils. J Immunol 2004; 172:5727-33.
-
(2004)
J Immunol
, vol.172
, pp. 5727-5733
-
-
Strassheim, D.1
Asehnoune, K.2
Park, J.S.3
-
62
-
-
30544451546
-
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
-
Hacker H, Redecke V, Blagoev B et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 2006; 439:204-7.
-
(2006)
Nature
, vol.439
, pp. 204-207
-
-
Hacker, H.1
Redecke, V.2
Blagoev, B.3
-
63
-
-
30544447047
-
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
-
Oganesyan G, Saha SK, Guo B et al. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 2006; 43:208-11.
-
(2006)
Nature
, vol.43
, pp. 208-211
-
-
Oganesyan, G.1
Saha, S.K.2
Guo, B.3
-
64
-
-
5444274514
-
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai T, Sato S, Ishii KJ et al. Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 2004; 5:1061-8.
-
(2004)
Nat Immunol
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
-
65
-
-
7444250116
-
Role of a transductional- transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling
-
Honda K, Yanai H, Mizutani T et al. Role of a transductional- transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling. Proc Natl Acad Sci USA 2004; 101:15416-21.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15416-15421
-
-
Honda, K.1
Yanai, H.2
Mizutani, T.3
-
66
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
Takaoka A, Yanai H, Kondo S et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 2005; 434:243-9.
-
(2005)
Nature
, vol.434
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
-
67
-
-
27644548945
-
Negative regulation of Toll-like-receptor signaling by IRF-4
-
Negishi H, Ohba Y, Yanai H et al. Negative regulation of Toll-like-receptor signaling by IRF-4. Proc Natl Acad Sci USA 2005; 102:15989-94.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15989-15994
-
-
Negishi, H.1
Ohba, Y.2
Yanai, H.3
-
68
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H et al. Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 2003; 301:640-3.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
-
69
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto M, Sato S, Hemmi H et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002; 420:324-9.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
-
70
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
Yamamoto M, Sato S, Hemmi H et al. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 2003; 4:1144-50.
-
(2003)
Nat Immunol
, vol.4
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
-
71
-
-
33646746802
-
TRAF3: A new component of the TLR-signaling apparatus
-
Hoebe K, Beutler B. TRAF3: a new component of the TLR-signaling apparatus. Trends Mol Med 2006; 12:187-9.
-
(2006)
Trends Mol Med
, vol.12
, pp. 187-189
-
-
Hoebe, K.1
Beutler, B.2
-
72
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai T, Takeuchi O, Fujita T et al. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J Immunol 2001; 167:5887-94.
-
(2001)
J Immunol
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
-
73
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation
-
Meylan E, Burns K, Hofmann K et al. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol 2004; 5:503-7.
-
(2004)
Nat Immunol
, vol.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
-
74
-
-
0037080024
-
Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
-
Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002; 168:554-61.
-
(2002)
J Immunol
, vol.168
, pp. 554-561
-
-
Zarember, K.A.1
Godowski, P.J.2
-
75
-
-
0036570169
-
Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S et al. Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002; 168:4531-7.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
76
-
-
0034123135
-
Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
-
Muzio M, Bosisio D, Polentarutti N et al. Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol 2000; 164:5998-6004.
-
(2000)
J Immunol
, vol.164
, pp. 5998-6004
-
-
Muzio, M.1
Bosisio, D.2
Polentarutti, N.3
-
77
-
-
0034617074
-
Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin
-
Wang ZM, Liu C, Dziarski R. Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin. J Biol Chem 2000; 275:20260-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 20260-20267
-
-
Wang, Z.M.1
Liu, C.2
Dziarski, R.3
-
78
-
-
29144532165
-
Characterization of Toll-like receptors in primary lung epithelial cells: Strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response
-
Ritter M, Mennerich D, Weith A, Seither P. Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response. J Inflamm 2005; 2:16.
-
(2005)
J Inflamm
, vol.2
, pp. 16
-
-
Ritter, M.1
Mennerich, D.2
Weith, A.3
Seither, P.4
-
79
-
-
0033179531
-
Regulation of macrophage chemokine expression by lipopolysaccharide in vitro and in vivo
-
Kopydlowski KM, Salkowski CA, Cody MJ et al. Regulation of macrophage chemokine expression by lipopolysaccharide in vitro and in vivo. J Immunol 1999; 163:1537-44.
-
(1999)
J Immunol
, vol.163
, pp. 1537-1544
-
-
Kopydlowski, K.M.1
Salkowski, C.A.2
Cody, M.J.3
-
80
-
-
0031848913
-
Pulmonary and hepatic gene expression following cecal ligation and puncture: Monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration
-
Salkowski CA, Detore G, Franks A, Falk MC, Vogel SN. Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration. Infect Immun 1998; 66:3569-78.
-
(1998)
Infect Immun
, vol.66
, pp. 3569-3578
-
-
Salkowski, C.A.1
Detore, G.2
Franks, A.3
Falk, M.C.4
Vogel, S.N.5
-
81
-
-
0030825407
-
Chemokines
-
Rollins BJ. Chemokines. Blood 1997; 90:909-28.
-
(1997)
Blood
, vol.90
, pp. 909-928
-
-
Rollins, B.J.1
-
82
-
-
0030045179
-
Expression and regulation of chemokines in bacterial pneumonia
-
Standiford TJ, Kunkel SL, Greenberger MJ, Laichalk LL, Strieter RM. Expression and regulation of chemokines in bacterial pneumonia. J Leukoc Biol 1996; 59:24-8.
-
(1996)
J Leukoc Biol
, vol.59
, pp. 24-28
-
-
Standiford, T.J.1
Kunkel, S.L.2
Greenberger, M.J.3
Laichalk, L.L.4
Strieter, R.M.5
-
83
-
-
16344376747
-
Impaired toll-like receptor 9 expression in alveolar macrophages with no sensitivity to CpG DNA
-
Suzuki K, Suda T, Naito T, Ide K, Chida K, Nakamura H. Impaired toll-like receptor 9 expression in alveolar macrophages with no sensitivity to CpG DNA. Am J Respir Crit Care Med 2005; 171:707-13.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 707-713
-
-
Suzuki, K.1
Suda, T.2
Naito, T.3
Ide, K.4
Chida, K.5
Nakamura, H.6
-
84
-
-
17644365720
-
The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation
-
Hollingsworth JW, Chen BJ, Brass DM et al. The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation. Am J Respir Crit Care Med 2005; 171:806-13.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 806-813
-
-
Hollingsworth, J.W.1
Chen, B.J.2
Brass, D.M.3
-
85
-
-
33645843063
-
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
-
Lotz M, Gutle D, Walther S, Menard S, Bogdan C, Hornef MW. Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J Exp Med 2006; 203:973-84.
-
(2006)
J Exp Med
, vol.203
, pp. 973-984
-
-
Lotz, M.1
Gutle, D.2
Walther, S.3
Menard, S.4
Bogdan, C.5
Hornef, M.W.6
-
86
-
-
3042568807
-
What can we learn from highly purified neutrophils?
-
Sabroe I, Prince LR, Dower SK, Walmsley SR, Chilvers ER, Whyte MK. What can we learn from highly purified neutrophils? Biochem Soc Trans 2004; 32:468-9.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 468-469
-
-
Sabroe, I.1
Prince, L.R.2
Dower, S.K.3
Walmsley, S.R.4
Chilvers, E.R.5
Whyte, M.K.6
-
87
-
-
0037883695
-
Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span
-
Sabroe I, Prince LR, Jones EC et al. Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span. J Immunol 2003; 170:5268-75.
-
(2003)
J Immunol
, vol.170
, pp. 5268-5275
-
-
Sabroe, I.1
Prince, L.R.2
Jones, E.C.3
-
88
-
-
17844382454
-
Regulation of human neutrophil chemokine receptor expression and function by activation of Toll-like receptors 2 and 4
-
Sabroe I, Jones EC, Whyte MK, Dower SK. Regulation of human neutrophil chemokine receptor expression and function by activation of Toll-like receptors 2 and 4. Immunology 2005; 115:90-8.
-
(2005)
Immunology
, vol.115
, pp. 90-98
-
-
Sabroe, I.1
Jones, E.C.2
Whyte, M.K.3
Dower, S.K.4
-
89
-
-
7244219855
-
The role of interleukin-1{beta} in direct and Toll-like receptor 4-mediated neutrophil activation and survival
-
Prince LR, Allen L, Jones EC et al. The role of interleukin-1{beta} in direct and Toll-like receptor 4-mediated neutrophil activation and survival. Am J Pathol 2004; 165:1819-26.
-
(2004)
Am J Pathol
, vol.165
, pp. 1819-1826
-
-
Prince, L.R.1
Allen, L.2
Jones, E.C.3
-
90
-
-
0036569658
-
Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: A critical role for monocytes in leukocyte lipopolysaccharide responses
-
Sabroe I, Jones EC, Usher LR, Whyte MK, Dower SK. Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses. J Immunol 2002; 168:4701-10.
-
(2002)
J Immunol
, vol.168
, pp. 4701-4710
-
-
Sabroe, I.1
Jones, E.C.2
Usher, L.R.3
Whyte, M.K.4
Dower, S.K.5
-
91
-
-
0034528582
-
CD14(+) cells are necessary for increased survival of eosinophils in response to lipopolysaccharide
-
Meerschaert J, Busse WW, Bertics PJ, Mosher DF. CD14(+) cells are necessary for increased survival of eosinophils in response to lipopolysaccharide. Am J Respir Cell Mol Biol 2000; 23:780-7.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 780-787
-
-
Meerschaert, J.1
Busse, W.W.2
Bertics, P.J.3
Mosher, D.F.4
-
92
-
-
0027938844
-
Requirement for lymphocytes and resident macrophages in LPS-induced pleural eosinophil accumulation
-
Bozza PT, Castro-Faria-Neto HC, Penido C et al. Requirement for lymphocytes and resident macrophages in LPS-induced pleural eosinophil accumulation. J Leukoc Biol 1994; 56:151-8.
-
(1994)
J Leukoc Biol
, vol.56
, pp. 151-158
-
-
Bozza, P.T.1
Castro-Faria-Neto, H.C.2
Penido, C.3
-
93
-
-
0031570944
-
The role of gammadelta T lymphocytes in lipopolysaccharide-induced eosinophil accumulation into the mouse pleural cavity
-
Penido C, Castro-Faria-Neto HC, Larangeira AP et al. The role of gammadelta T lymphocytes in lipopolysaccharide-induced eosinophil accumulation into the mouse pleural cavity. J Immunol 1997; 159:853-60.
-
(1997)
J Immunol
, vol.159
, pp. 853-860
-
-
Penido, C.1
Castro-Faria-Neto, H.C.2
Larangeira, A.P.3
-
94
-
-
0038281539
-
Expression and function of Toll-like receptors 2 and 4 in human keratinocytes
-
Pivarcsi A, Bodai L, Rethi B et al. Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int Immunol 2003; 15:721-30.
-
(2003)
Int Immunol
, vol.15
, pp. 721-730
-
-
Pivarcsi, A.1
Bodai, L.2
Rethi, B.3
-
95
-
-
20144389424
-
Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes
-
Kollisch G, Kalali BN, Voelcker V et al. Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. Immunology 2005; 114:531-41.
-
(2005)
Immunology
, vol.114
, pp. 531-541
-
-
Kollisch, G.1
Kalali, B.N.2
Voelcker, V.3
-
96
-
-
0037297756
-
Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung
-
Droemann D, Goldmann T, Branscheid D et al. Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung. Histochem Cell Biol 2003; 119:103-8.
-
(2003)
Histochem Cell Biol
, vol.119
, pp. 103-108
-
-
Droemann, D.1
Goldmann, T.2
Branscheid, D.3
-
97
-
-
1642494708
-
Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: Evidence for an intracellular compartmentalization of TLR4
-
Guillot L, Medjane S, Le-Barillec K et al. Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4. J Biol Chem 2004; 279:2712-18.
-
(2004)
J Biol Chem
, vol.279
, pp. 2712-2718
-
-
Guillot, L.1
Medjane, S.2
Le-Barillec, K.3
-
98
-
-
17044385039
-
TLR signaling in the gut in health and disease
-
Abreu MT, Fukata M, Arditi M. TLR signaling in the gut in health and disease. J Immunol 2005; 174:4453-60.
-
(2005)
J Immunol
, vol.174
, pp. 4453-4460
-
-
Abreu, M.T.1
Fukata, M.2
Arditi, M.3
-
99
-
-
20344386219
-
Characterization of Toll-like receptors in the female reproductive tract in humans
-
Fazeli A, Bruce C, Anumba DO. Characterization of Toll-like receptors in the female reproductive tract in humans. Hum Reprod 2005; 20:1372-8.
-
(2005)
Hum Reprod
, vol.20
, pp. 1372-1378
-
-
Fazeli, A.1
Bruce, C.2
Anumba, D.O.3
-
100
-
-
0034646695
-
Bacterial lipopolysaccharide activates NF-kappaB through Toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells
-
Faure E, Equils O, Sieling PA et al. Bacterial lipopolysaccharide activates NF-kappaB through Toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. J Biol Chem 2000; 275:11058-63.
-
(2000)
J Biol Chem
, vol.275
, pp. 11058-11063
-
-
Faure, E.1
Equils, O.2
Sieling, P.A.3
-
101
-
-
15444380849
-
IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression
-
Tissari J, Siren J, Meri S, Julkunen I, Matikainen S. IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J Immunol 2005; 174:4289-94.
-
(2005)
J Immunol
, vol.174
, pp. 4289-4294
-
-
Tissari, J.1
Siren, J.2
Meri, S.3
Julkunen, I.4
Matikainen, S.5
-
102
-
-
4143100140
-
-
Li J, Ma Z, Tang ZL, Stevens T, Pitt B, Li S. CpG DNA-mediated immune response in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 2004; 287:L552-8.
-
Li J, Ma Z, Tang ZL, Stevens T, Pitt B, Li S. CpG DNA-mediated immune response in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 2004; 287:L552-8.
-
-
-
-
103
-
-
23944451105
-
Proinflammatory phenotype of vascular smooth muscle cells: Role of efficient Toll-like receptor 4 signaling
-
Yang X, Coriolan D, Murthy V, Schultz K, Golenbock DT, Beasley D. Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling. Am J Physiol Heart Circ Physiol 2005; 289:H1069-76.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Yang, X.1
Coriolan, D.2
Murthy, V.3
Schultz, K.4
Golenbock, D.T.5
Beasley, D.6
-
104
-
-
17644390987
-
Agonists of Toll-like receptors 2 and 4 activate airway smooth muscle via mononuclear leukocytes
-
Morris GE, Whyte MK, Martin GF, Jose PJ, Dower SK, Sabroe I. Agonists of Toll-like receptors 2 and 4 activate airway smooth muscle via mononuclear leukocytes. Am J Respir Crit Care Med 2005; 171:814-22.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 814-822
-
-
Morris, G.E.1
Whyte, M.K.2
Martin, G.F.3
Jose, P.J.4
Dower, S.K.5
Sabroe, I.6
-
105
-
-
0033559522
-
The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells
-
Sauty A, Dziejman M, Taha RA et al. The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J Immunol 1999; 162:3549-58.
-
(1999)
J Immunol
, vol.162
, pp. 3549-3558
-
-
Sauty, A.1
Dziejman, M.2
Taha, R.A.3
-
106
-
-
18244391711
-
Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: Implications for tissue mast cell migration
-
Brightling CE, Kaur D, Berger P, Morgan AJ, Wardlaw AJ, Bradding P. Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. J Leukoc Biol 2005; 77:759-66.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 759-766
-
-
Brightling, C.E.1
Kaur, D.2
Berger, P.3
Morgan, A.J.4
Wardlaw, A.J.5
Bradding, P.6
-
107
-
-
18644380441
-
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle
-
Brightling CE, Ammit AJ, Kaur D et al. The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med 2005; 171:1103-8.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1103-1108
-
-
Brightling, C.E.1
Ammit, A.J.2
Kaur, D.3
-
108
-
-
0037198418
-
Mast-cell infiltration of airway smooth muscle in asthma
-
Brightling CE, Bradding P, Symon FA, Holgate ST, Wardlaw AJ, Pavord ID. Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med 2002; 346:1699-705.
-
(2002)
N Engl J Med
, vol.346
, pp. 1699-1705
-
-
Brightling, C.E.1
Bradding, P.2
Symon, F.A.3
Holgate, S.T.4
Wardlaw, A.J.5
Pavord, I.D.6
-
109
-
-
33748430369
-
Regulation of Toll-like receptor 4-induced pro-asthmatic changes in airway smooth muscle function by opposing actions of ERK1/2 and p38 MAPK signaling
-
Shan X, Hu A, Veler H et al. Regulation of Toll-like receptor 4-induced pro-asthmatic changes in airway smooth muscle function by opposing actions of ERK1/2 and p38 MAPK signaling. Am J Physiol Lung Cell Mol Physiol 2006; 291:L324-33.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Shan, X.1
Hu, A.2
Veler, H.3
-
111
-
-
33646487278
-
Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells
-
Liu H, Komai-Koma M, Xu D, Liew FY. Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci USA 2006; 103:7048-53.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7048-7053
-
-
Liu, H.1
Komai-Koma, M.2
Xu, D.3
Liew, F.Y.4
-
112
-
-
23044454798
-
Expression and function of Toll-like receptor on T cells
-
Xu D, Komai-Koma M, Liew FY. Expression and function of Toll-like receptor on T cells. Cell Immunol 2005; 233:85-9.
-
(2005)
Cell Immunol
, vol.233
, pp. 85-89
-
-
Xu, D.1
Komai-Koma, M.2
Liew, F.Y.3
-
113
-
-
0742324857
-
Toll-like receptors and acquired immunity
-
Pasare C, Medzhitov R. Toll-like receptors and acquired immunity. Semin Immunol 2004; 16:23-6.
-
(2004)
Semin Immunol
, vol.16
, pp. 23-26
-
-
Pasare, C.1
Medzhitov, R.2
-
114
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5:987-95.
-
(2004)
Nat Immunol
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
115
-
-
21344465240
-
TLR signalling and the function of dendritic cells
-
Hemmi H, Akira S. TLR signalling and the function of dendritic cells. Chem Immunol Allergy 2005; 86:120-35.
-
(2005)
Chem Immunol Allergy
, vol.86
, pp. 120-135
-
-
Hemmi, H.1
Akira, S.2
-
116
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392:245-52.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
117
-
-
0347146027
-
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
-
Hoebe K, Janssen EM, Kim SO et al. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol 2003; 4:1223-9.
-
(2003)
Nat Immunol
, vol.4
, pp. 1223-1229
-
-
Hoebe, K.1
Janssen, E.M.2
Kim, S.O.3
-
118
-
-
0141703238
-
Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection
-
Honda K, Sakaguchi S, Nakajima C et al. Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc Natl Acad Sci USA 2003; 100:10872-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10872-10877
-
-
Honda, K.1
Sakaguchi, S.2
Nakajima, C.3
-
119
-
-
0036796384
-
Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation
-
Hoshino K, Kaisho T, Iwabe T, Takeuchi O, Akira S. Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation. Int Immunol 2002; 14:1225-31.
-
(2002)
Int Immunol
, vol.14
, pp. 1225-1231
-
-
Hoshino, K.1
Kaisho, T.2
Iwabe, T.3
Takeuchi, O.4
Akira, S.5
-
120
-
-
0034954034
-
Interferons alpha and beta as immune regulators - a new look
-
Biron CA. Interferons alpha and beta as immune regulators - a new look. Immunity 2001; 14:661-4.
-
(2001)
Immunity
, vol.14
, pp. 661-664
-
-
Biron, C.A.1
-
122
-
-
33746987547
-
Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection
-
Oliver BG, Johnston SL, Baraket M et al. Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection. Respir Res 2006; 7:71.
-
(2006)
Respir Res
, vol.7
, pp. 71
-
-
Oliver, B.G.1
Johnston, S.L.2
Baraket, M.3
-
123
-
-
1342308233
-
Something old, something new: Indoor endotoxin, allergens and asthma
-
Liu AH. Something old, something new: indoor endotoxin, allergens and asthma. Paediatr Respir Rev 2004; 5 (Suppl. A):S65-71.
-
(2004)
Paediatr Respir Rev
, vol.5
, Issue.SUPPL. A
-
-
Liu, A.H.1
-
124
-
-
0030451097
-
Severity of asthma is related to endotoxin in house dust
-
Michel O, Kips J, Duchateau J et al. Severity of asthma is related to endotoxin in house dust. Am J Respir Crit Care Med 1996; 154:1641-6.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 1641-1646
-
-
Michel, O.1
Kips, J.2
Duchateau, J.3
-
125
-
-
27744586059
-
Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin
-
Noulin N, Quesniaux VF, Schnyder-Candrian S et al. Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin. J Immunol 2005; 175:6861-9.
-
(2005)
J Immunol
, vol.175
, pp. 6861-6869
-
-
Noulin, N.1
Quesniaux, V.F.2
Schnyder-Candrian, S.3
-
126
-
-
16844363111
-
Neutrophils and keratinocytes in innate immunity - cooperative actions to provide antimicrobial defense at the right time and place
-
Borregaard N, Theilgaard-Monch K, Cowland JB, Stahle M, Sorensen OE. Neutrophils and keratinocytes in innate immunity - cooperative actions to provide antimicrobial defense at the right time and place. J Leukoc Biol 2005; 77:439-43.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 439-443
-
-
Borregaard, N.1
Theilgaard-Monch, K.2
Cowland, J.B.3
Stahle, M.4
Sorensen, O.E.5
-
127
-
-
0030747245
-
Epithelial cells as sensors for microbial infection
-
Kagnoff MF, Eckmann L. Epithelial cells as sensors for microbial infection. J Clin Invest 1997; 100:6-10.
-
(1997)
J Clin Invest
, vol.100
, pp. 6-10
-
-
Kagnoff, M.F.1
Eckmann, L.2
-
128
-
-
0346366980
-
Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2
-
Hertz CJ, Wu Q, Porter EM et al. Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. J Immunol 2003; 171:6820-6.
-
(2003)
J Immunol
, vol.171
, pp. 6820-6826
-
-
Hertz, C.J.1
Wu, Q.2
Porter, E.M.3
-
129
-
-
0038189571
-
Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors
-
Sorensen OE, Cowland JB, Theilgaard-Monch K, Liu L, Ganz T, Borregaard N. Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol 2003; 170:5583-9.
-
(2003)
J Immunol
, vol.170
, pp. 5583-5589
-
-
Sorensen, O.E.1
Cowland, J.B.2
Theilgaard-Monch, K.3
Liu, L.4
Ganz, T.5
Borregaard, N.6
-
130
-
-
16844380318
-
Interactions between neutrophil-derived antimicrobial peptides and airway epithelial cells
-
van Wetering S, Tjabringa GS, Hiemstra PS. Interactions between neutrophil-derived antimicrobial peptides and airway epithelial cells. J Leukoc Biol 2005; 77:444-50.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 444-450
-
-
van Wetering, S.1
Tjabringa, G.S.2
Hiemstra, P.S.3
-
131
-
-
0037443571
-
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: Role of the CCL2-CCR2 axis
-
Maus UA, Waelsch K, Kuziel WA et al. Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis. J Immunol 2003; 170:3273-8.
-
(2003)
J Immunol
, vol.170
, pp. 3273-3278
-
-
Maus, U.A.1
Waelsch, K.2
Kuziel, W.A.3
-
132
-
-
0037218616
-
By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide
-
Liu L, Roberts AA, Ganz T. By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J Immunol 2003; 170:575-80.
-
(2003)
J Immunol
, vol.170
, pp. 575-580
-
-
Liu, L.1
Roberts, A.A.2
Ganz, T.3
-
133
-
-
33646872285
-
Lipopolysaccharide-induced IL-1beta production by human uterine macrophages up-regulates uterine epithelial cell expression of human beta-defensin 2
-
Pioli PA, Weaver LK, Schaefer TM, Wright JA, Wira CR, Guyre PM. Lipopolysaccharide-induced IL-1beta production by human uterine macrophages up-regulates uterine epithelial cell expression of human beta-defensin 2. J Immunol 2006; 176:6647-55.
-
(2006)
J Immunol
, vol.176
, pp. 6647-6655
-
-
Pioli, P.A.1
Weaver, L.K.2
Schaefer, T.M.3
Wright, J.A.4
Wira, C.R.5
Guyre, P.M.6
-
134
-
-
0042261764
-
Monocytes initiate a cycle of leukocyte recruitment when cocultured with endothelial cells
-
Tsouknos A, Nash GB, Rainger GE. Monocytes initiate a cycle of leukocyte recruitment when cocultured with endothelial cells. Atherosclerosis 2003; 170:49-58.
-
(2003)
Atherosclerosis
, vol.170
, pp. 49-58
-
-
Tsouknos, A.1
Nash, G.B.2
Rainger, G.E.3
-
135
-
-
31144442984
-
Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells
-
Groskreutz DJ, Monick MM, Powers LS, Yarovinsky TO, Look DC, Hunninghake GW. Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells. J Immunol 2006; 176:1733-40.
-
(2006)
J Immunol
, vol.176
, pp. 1733-1740
-
-
Groskreutz, D.J.1
Monick, M.M.2
Powers, L.S.3
Yarovinsky, T.O.4
Look, D.C.5
Hunninghake, G.W.6
-
136
-
-
0347362785
-
Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin
-
Monick MM, Yarovinsky TO, Powers LS et al. Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin. J Biol Chem 2003; 278:53035-44.
-
(2003)
J Biol Chem
, vol.278
, pp. 53035-53044
-
-
Monick, M.M.1
Yarovinsky, T.O.2
Powers, L.S.3
-
137
-
-
14044267522
-
Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
-
Guillot L, Le Goffic R, Bloch S et al. Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem 2005; 280:5571-80.
-
(2005)
J Biol Chem
, vol.280
, pp. 5571-5580
-
-
Guillot, L.1
Le Goffic, R.2
Bloch, S.3
|