Role of TLR-2 in the Activation of Nuclear Factor κB by Oxidative Stress in Cardiac Myocytes

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 5197-5203

  Frantz, Stefan ^b   Kelly, Ralph A ^b   Bourcier, Todd ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR SYSTEM; CELLS; HYDROGEN PEROXIDE; PATHOLOGY; STRESSES; TOXICITY; TUMORS;

CYTOTOXICITY; TUMOR NECROSIS FACTOR;

PROTEINS;

ALPHA TOLL LIKE RECEPTOR 2 ANTIBODY; ANTIBODY; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OCTAMER TRANSCRIPTION FACTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; TLR2 PROTEIN, RAT; TLR4 PROTEIN, RAT; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANTIAPOPTOTIC ACTIVITY; APOPTOSIS; ARTICLE; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME PHOSPHORYLATION; FIBROBLAST; GENE OVEREXPRESSION; HEART DISEASE; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; IMMUNITY; INTRACELLULAR TRANSPORT; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; RECEPTOR BLOCKING; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL NUCLEUS; CYTOLOGY; GENETICS; HAMSTER; HEART MUSCLE; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL NUCLEUS; CELLS, CULTURED; CHO CELLS; CRICETINAE; DROSOPHILA PROTEINS; HYDROGEN PEROXIDE; MEMBRANE GLYCOPROTEINS; MYOCARDIUM; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0035895913     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009160200     Document Type: Article

References (42)

1. Medzhitov, R., and Janeway, C., Jr. (2000) N. Engl. J. Med. 343, 338-344
2. Schuster, J. M., and Nelson, P. S. (2000) J. Leukoc. Biol. 67, 767-773
3. Rock, F. L., Hardiman, G., Timans, J. C., Kastelein, R. A., and Bazan, J. F. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 588-593
4. Takeuchi, O., Kawai, T., Sanjo, H., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Takeda, K., and Akira, S. (1999) Gene 231, 59-65
5. Medzhitov, R., Preston-Hurlburt, P., and Janeway, C. A., Jr. (1997) Nature 388, 394-397
6. Muzio, M., Natoli, G., Saccani, S., Levrero, M., and Mantovani, A. (1998) J. Exp. Med. 187, 2097-2101
7. Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., and Kirschning, C. J. (1999) J. Biol. Chem. 274, 17406-1749
8. Brightbill, H. D., Libraty, D. H., Krutzik, S. R., Yang, R. B., Belisle, J. T., Bleharski, J. R., Maitland, M., Norgard, M. V., Plevy, S. E., Smale, S. T., Brennan, P. J., Bloom, B. R., Godowski, P. J., and Modlin, R. L. (1999) Science 285, 732-736
9. Underhill, D. M., Ozinsky, A., Smith, K. D., and Aderem, A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14459-14463
10. Hirschfeld, M., Kirschning, C. J., Schwandner, R., Wesche, H., Weis, J. H., Wooten, R. M., and Weis, J. J. (1999) J. Immunol. 163, 2382-2386
11. Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., and Akira, S. (1999) J. Immunol. 162, 3749-3752
12. Poltorak, A., He, X., Smirnova, I., Liu, M. Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ricciardi-Castagnoli, P., Layton, B., and Beutler, B. (1998) Science 282, 2085-2088
13. Qureshi, S. T., Lariviere, L., Leveque, G., Clermont, S., Moore, K. J., Gros, P., and Malo, D. (1999) J. Exp. Med. 189, 615-625
14. Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., and Akira, S. (1999) Immunity 11, 443-451
15. Arbour, N. C., Lorenz, E., Schutte, B. C., Zabner, J., Kline, J. N., Jones, M., Frees, K., Watt, J. L., and Schwartz, D. A. (2000) Nat. Genet. 25, 187-191
16. Zhang, F. X., Kirschning, C. J., Mancinelli, R., Xu, X. P., Jin, Y., Faure, E., Mantovani, A., Rothe, M., Muzio, M., and Arditi, M. (1999) J. Biol. Chem. 274, 7611-7614
17. Frantz, S., Kobzik, L., Kim, Y. D., Fukazawa, R., Medzhitov, R., Lee, R. T., and Kelly, R. A. (1999) J. Clin. Invest. 104, 271-280
18. Ohashi, K., Burkart, V., Flohe, S., and Kolb, H. (2000) J. Immunol. 164, 558-561
19. Matzinger, P. (1998) Semin. Immunol. 10, 399-415
20. von Harsdorf, R., Li, P. F., and Dietz, R. (1999) Circulation 99, 2934-2941
21. Bowie, A., and O'Neill, L. A. (2000) Biochem. Pharmacol. 59, 13-23
22. Peng, M., Huang, L., Xie, Z. J., Huang, W. H., and Askari, A. (1995) Cell Mol. Biol. Res. 41, 189-197
23. Lien, E., Sellati, T. J., Yoshimura, A., Flo, T. H., Rawadi, G., Finberg, R. W., Carroll, J. D., Espevik, T., Ingalls, R. R., Radolf, J. D., and Golenbock, D. T. (1999) J. Biol. Chem. 274, 33419-33425
24. Bourcier, T. (1999) in Methods in Molecular Medicine, Vascular Disease (Baker, A. H., ed) pp. 159-167, Humana Press, Totowa, NJ
25. Heine, H., Kirschning, C., Lien, E., Monks, B., Rothe, M., and Golenbock, D. (1999) J. Immunol. 162, 6971-6975
26. Guyton, K. Z., Liu, Y., Gorospe, M., Xu, Q., and Holbrook, N. J. (1996) J. Biol. Chem. 271, 4138-4142
27. Barkett, M., and Gilmore, T. D. (1999) Oncogene 18, 6910-6924
28. Mustapha, S., Kirshner, A., De Moissac, D., and Kirshenbaum, L. A. (2000) Am. J. Physiol. Heart Circ. Physiol. 279, H939-H945
29. Martin, S. J., Reutelingsperger, C. P., McGahon, A. J., Rader, J. A., van Schie, R. C., LaFace, D. M., and Green, D. R. (1995) J. Exp. Med. 182, 1545-1556
30. Janeway, C. A., Jr. (1992) Immunol. Today 13, 11-16
31. Medzhitov, R., and Janeway, C. A., Jr. (1997) Cell 91, 295-298
32. Matzinger, P. (1994) Annu. Rev. Immunol. 12, 991-1045
33. Kapadia, S., Dibbs, Z., Kurrelmeyer, K., Kalra, D., Seta, Y., Wang, F., Bozkurt, B., Oral, H., Sivasubramanian, N., and Mann, D. L. (1998) Cardiol. Clin. 16, 645-656
34. Flohe, L., Brigelius-Flohe, R., Saliou, C., Traber, M. G., and Packer, L. (1997) Free Radic. Biol. Med. 22, 1115-1126
35. Muller, J. M., Rupec, R. A., and Baeuerle, P. A. (1997) Methods 11, 301-312
36. Yang, R. B., Mark, M. R., Gurney, A. L., and Godowski, P. J. (1999) J. Immunol. 163, 639-643
37. Turner, N. A., Xia, F., Azhar, G., Zhang, X., Liu, L., and Wei, J. Y. (1998) J. Mol. Cell Cardiol. 30, 1789-1801
38. Kol, A., Bourcier, T., Lichtman, A. H., and Libby, P. (1999) J. Clin. Invest. 103, 571-577
39. Aliprantis, A. O., Yang, R. B., Mark, M. R., Suggett, S., Devaux, B., Radolf, J. D., Klimpel, G. R., Godowski, P., and Zychlinsky, A. (1999) Science 285, 736-739
40. Aliprantis, A. O., Yang, R. B., Weiss, D. S., Godowski, P., and Zychlinsky, A. (2000) EMBO J. 19, 3325-3336
41. Anversa, P., Leri, A., Beltrami, C. A., Guerra, S., and Kajstura, J. (1998) Lab. Invest. 78, 767-786
42. Haunstetter, A., and Izumo, S. (1998) Circ. Res. 82, 1111-1129