Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

Nature Immunology

Volumn 4, Issue 12, 2003, Pages 1223-1229

  Hoebe, Kasper ^a   Janssen, Edith M ^b   Kim, Sung O ^a   Alexopoulou, Lena ^c   Flavell, Richard A ^c   Han, Jiahuai ^a   Beutler, Bruce ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; B7 ANTIGEN; BETA INTERFERON; CD40 ANTIGEN; CD86 ANTIGEN; CYTOKINE; DOUBLE STRANDED RNA; INTERFERON RECEPTOR; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, CD; ANTIGENS, CD40; ANTIGENS, CD80; ANTIGENS, CD86; ANTIGENS, DIFFERENTIATION; EIF-2 KINASE; IMMUNITY, CELLULAR; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; MYELOID DIFFERENTIATION FACTOR 88; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, INTERFERON; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; UP-REGULATION;

EID: 0347146027     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1010     Document Type: Article

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