-
1
-
-
0038630396
-
Artemisinin, a novel antimalarial drug: biochemical and molecular approaches for enhanced production
-
Abdin M.Z., Israr M., Rehman R.U., and Jain S.K. Artemisinin, a novel antimalarial drug: biochemical and molecular approaches for enhanced production. Planta Med. 69 (2003) 289-299
-
(2003)
Planta Med.
, vol.69
, pp. 289-299
-
-
Abdin, M.Z.1
Israr, M.2
Rehman, R.U.3
Jain, S.K.4
-
2
-
-
28244495048
-
Golden rice - five years on the road - five years to go?
-
Al Babili S., and Beyer P. Golden rice - five years on the road - five years to go?. Trends Plant Sci. 10 (2005) 565-573
-
(2005)
Trends Plant Sci.
, vol.10
, pp. 565-573
-
-
Al Babili, S.1
Beyer, P.2
-
3
-
-
0036042698
-
Genomic analysis of the terpenoid synthase (AtTPS) gene family of Arabidopsis thaliana
-
Aubourg S., Lecharny A., and Bohlmann J. Genomic analysis of the terpenoid synthase (AtTPS) gene family of Arabidopsis thaliana. Mol. Genet. Genomics 267 (2002) 730-745
-
(2002)
Mol. Genet. Genomics
, vol.267
, pp. 730-745
-
-
Aubourg, S.1
Lecharny, A.2
Bohlmann, J.3
-
4
-
-
0034787233
-
Metabolic engineering of isoprenoids
-
Barkovich R., and Liao J.C. Metabolic engineering of isoprenoids. Metab. Eng. 3 (2001) 27-39
-
(2001)
Metab. Eng.
, vol.3
, pp. 27-39
-
-
Barkovich, R.1
Liao, J.C.2
-
5
-
-
13544263331
-
Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua
-
Bertea C.M., Freije J.R., Van der Woude H., Verstappen F.W., Perk L., Marquez V., De Kraker J.W., Posthumus M.A., Jansen B.J., de Groot A., Franssen M.C., and Bouwmeester H.J. Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua. Planta Med. 71 (2005) 40-47
-
(2005)
Planta Med.
, vol.71
, pp. 40-47
-
-
Bertea, C.M.1
Freije, J.R.2
Van der Woude, H.3
Verstappen, F.W.4
Perk, L.5
Marquez, V.6
De Kraker, J.W.7
Posthumus, M.A.8
Jansen, B.J.9
de Groot, A.10
Franssen, M.C.11
Bouwmeester, H.J.12
-
6
-
-
6444235290
-
Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol
-
Besumbes O., Sauret-Gueto S., Phillips M.A., Imperial S., Rodriguez-Concepcion M., and Boronat A. Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol. Biotechnol. Bioeng. 88 (2004) 168-175
-
(2004)
Biotechnol. Bioeng.
, vol.88
, pp. 168-175
-
-
Besumbes, O.1
Sauret-Gueto, S.2
Phillips, M.A.3
Imperial, S.4
Rodriguez-Concepcion, M.5
Boronat, A.6
-
7
-
-
0036373903
-
Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum
-
Brodelius M., Lundgren A., Mercke P., and Brodelius P.E. Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum. Eur. J. Biochem. 269 (2002) 3570-3577
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 3570-3577
-
-
Brodelius, M.1
Lundgren, A.2
Mercke, P.3
Brodelius, P.E.4
-
8
-
-
2642547256
-
Molecular cloning and characterization of a cytochrome P450 taxoid 2α-hydroxylase involved in Taxol biosynthesis
-
Chau M., and Croteau R. Molecular cloning and characterization of a cytochrome P450 taxoid 2α-hydroxylase involved in Taxol biosynthesis. Arch. Biochem. Biophys. 427 (2004) 48-57
-
(2004)
Arch. Biochem. Biophys.
, vol.427
, pp. 48-57
-
-
Chau, M.1
Croteau, R.2
-
9
-
-
18044394444
-
The secondary metabolism of Arabidopsis thaliana: growing like a weed
-
D'Auria J.C., and Gershenzon J. The secondary metabolism of Arabidopsis thaliana: growing like a weed. Curr. Opin. Plant Biol. 8 (2005) 308-316
-
(2005)
Curr. Opin. Plant Biol.
, vol.8
, pp. 308-316
-
-
D'Auria, J.C.1
Gershenzon, J.2
-
10
-
-
33751231561
-
Protoberberine alkaloids
-
Da Cunha E.V., Fechinei I.M., Guedes D.N., Barbosa-Filho J.M., and Da Silva M.S. Protoberberine alkaloids. Alkaloids Chem. Biol. 62 (2005) 1-75
-
(2005)
Alkaloids Chem. Biol.
, vol.62
, pp. 1-75
-
-
Da Cunha, E.V.1
Fechinei, I.M.2
Guedes, D.N.3
Barbosa-Filho, J.M.4
Da Silva, M.S.5
-
11
-
-
33645573250
-
Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae
-
Dejong J.M., Liu Y., Bollon A.P., Long R.M., Jennewein S., Williams D., and Croteau R.B. Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae. Biotechnol. Bioeng. 93 (2006) 212-224
-
(2006)
Biotechnol. Bioeng.
, vol.93
, pp. 212-224
-
-
Dejong, J.M.1
Liu, Y.2
Bollon, A.P.3
Long, R.M.4
Jennewein, S.5
Williams, D.6
Croteau, R.B.7
-
12
-
-
0025751609
-
Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack
-
Dittrich H., and Kutchan T.M. Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 9969-9973
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 9969-9973
-
-
Dittrich, H.1
Kutchan, T.M.2
-
14
-
-
0036695569
-
Recent advances in industrial carotenoid synthesis
-
Ernst H. Recent advances in industrial carotenoid synthesis. Pure Appl. Chem. 74 (2002) 1369-1382
-
(2002)
Pure Appl. Chem.
, vol.74
, pp. 1369-1382
-
-
Ernst, H.1
-
15
-
-
0034024497
-
Improving lycopene production in Escherichia coli by engineering metabolic control
-
Farmer W.R., and Liao J.C. Improving lycopene production in Escherichia coli by engineering metabolic control. Nat. Biotechnol. 18 (2000) 533-537
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 533-537
-
-
Farmer, W.R.1
Liao, J.C.2
-
16
-
-
0035128694
-
Precursor balancing for metabolic engineering of lycopene production in Escherichia coli
-
Farmer W.R., and Liao J.C. Precursor balancing for metabolic engineering of lycopene production in Escherichia coli. Biotechnol. Prog. 17 (2001) 57-61
-
(2001)
Biotechnol. Prog.
, vol.17
, pp. 57-61
-
-
Farmer, W.R.1
Liao, J.C.2
-
17
-
-
1542315589
-
The biosynthesis and nutritional uses of carotenoids
-
Fraser P.D., and Bramley P.M. The biosynthesis and nutritional uses of carotenoids. Prog. Lipid Res. 43 (2004) 228-265
-
(2004)
Prog. Lipid Res.
, vol.43
, pp. 228-265
-
-
Fraser, P.D.1
Bramley, P.M.2
-
18
-
-
0034892702
-
Biotransformation of tryptamine and secologanin into plant terpenoid indole alkaloids by transgenic yeast
-
Geerlings A., Redondo F.J., Contin A., Memelink J., van der H.R., and Verpoorte R. Biotransformation of tryptamine and secologanin into plant terpenoid indole alkaloids by transgenic yeast. Appl. Microbiol. Biotechnol. 56 (2001) 420-424
-
(2001)
Appl. Microbiol. Biotechnol.
, vol.56
, pp. 420-424
-
-
Geerlings, A.1
Redondo, F.J.2
Contin, A.3
Memelink, J.4
van der, H.R.5
Verpoorte, R.6
-
19
-
-
44049113918
-
Formation of salutaridine from (R)-reticuline by a membrane bound cytochrome P450 enzyme from Papaver somniferum
-
Gerardy R., and Zenk M.H. Formation of salutaridine from (R)-reticuline by a membrane bound cytochrome P450 enzyme from Papaver somniferum. Phytochemistry 32 (1993) 79-86
-
(1993)
Phytochemistry
, vol.32
, pp. 79-86
-
-
Gerardy, R.1
Zenk, M.H.2
-
20
-
-
0000613388
-
Purification and characterization of salutaridine NADPH 7-oxidoreductase from Papaver somniferum
-
Gerardy R., and Zenk M.H. Purification and characterization of salutaridine NADPH 7-oxidoreductase from Papaver somniferum. Phytochemistry 34 (1993) 125-132
-
(1993)
Phytochemistry
, vol.34
, pp. 125-132
-
-
Gerardy, R.1
Zenk, M.H.2
-
21
-
-
0037029080
-
A prospective study of tomato products, lycopene, and prostate cancer risk
-
Giovannucci E., Rimm E.B., Liu Y., Stampfer M.J., and Willett W.C. A prospective study of tomato products, lycopene, and prostate cancer risk. J. Natl. Cancer Inst. 94 (2002) 391-398
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 391-398
-
-
Giovannucci, E.1
Rimm, E.B.2
Liu, Y.3
Stampfer, M.J.4
Willett, W.C.5
-
22
-
-
0035903228
-
Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum
-
Grothe T., Lenz R., and Kutchan T.M. Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum. J. Biol. Chem. 276 (2001) 30717-30723
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30717-30723
-
-
Grothe, T.1
Lenz, R.2
Kutchan, T.M.3
-
23
-
-
0029079317
-
Isolation of Schizosaccharomyces pombe isopentenyl diphosphate isomerase cDNA clones by complementation and synthesis of the enzyme in Escherichia coli
-
Hahn F.M., and Poulter C.D. Isolation of Schizosaccharomyces pombe isopentenyl diphosphate isomerase cDNA clones by complementation and synthesis of the enzyme in Escherichia coli. J. Biol. Chem. 270 (1995) 11298-11303
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11298-11303
-
-
Hahn, F.M.1
Poulter, C.D.2
-
24
-
-
0031416208
-
Suspension cultured transgenic cells of Nicotiana tabacum expressing tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus produce strictosidine upon secologanin feeding
-
Hallard D., Van der Heijden R., Verpoorte R., Cardoso M.I.L., Pasquali G., Memelink J., and Hoge J.H.C. Suspension cultured transgenic cells of Nicotiana tabacum expressing tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus produce strictosidine upon secologanin feeding. Plant Cell Rep. 17 (1997) 50-54
-
(1997)
Plant Cell Rep.
, vol.17
, pp. 50-54
-
-
Hallard, D.1
Van der Heijden, R.2
Verpoorte, R.3
Cardoso, M.I.L.4
Pasquali, G.5
Memelink, J.6
Hoge, J.H.C.7
-
25
-
-
0034736046
-
Advances in flavonoid research since
-
Harborne J.B., and Williams C.A. Advances in flavonoid research since. Phytochemistry 55 (2000) 481-504
-
(2000)
Phytochemistry
, vol.55
, pp. 481-504
-
-
Harborne, J.B.1
Williams, C.A.2
-
26
-
-
0033057722
-
Expression of prokaryotic 1-deoxy-d-xylulose-5-phosphatases in Escherichia coli increases carotenoid and ubiquinone biosynthesis
-
Harker M., and Bramley P.M. Expression of prokaryotic 1-deoxy-d-xylulose-5-phosphatases in Escherichia coli increases carotenoid and ubiquinone biosynthesis. FEBS Lett. 448 (1999) 115-119
-
(1999)
FEBS Lett.
, vol.448
, pp. 115-119
-
-
Harker, M.1
Bramley, P.M.2
-
27
-
-
21244462769
-
Plasticity of the Streptomyces genome-evolution and engineering of new antibiotics
-
Hranueli D., Cullum J., Basrak B., Goldstein P., and Long P.F. Plasticity of the Streptomyces genome-evolution and engineering of new antibiotics. Curr. Med. Chem. 12 (2005) 1697-1704
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 1697-1704
-
-
Hranueli, D.1
Cullum, J.2
Basrak, B.3
Goldstein, P.4
Long, P.F.5
-
28
-
-
0034161828
-
Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum
-
Huang F.C., and Kutchan T.M. Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum. Phytochemistry 53 (2000) 555-564
-
(2000)
Phytochemistry
, vol.53
, pp. 555-564
-
-
Huang, F.C.1
Kutchan, T.M.2
-
29
-
-
0034838359
-
Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol
-
Huang Q., Roessner C.A., Croteau R., and Scott A.I. Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol. Bioorg. Med. Chem. 9 (2001) 2237-2242
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 2237-2242
-
-
Huang, Q.1
Roessner, C.A.2
Croteau, R.3
Scott, A.I.4
-
30
-
-
0037545559
-
Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster
-
Hwang E.I., Kaneko M., Ohnishi Y., and Horinouchi S. Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster. Appl. Environ. Microbiol. 69 (2003) 2699-2706
-
(2003)
Appl. Environ. Microbiol.
, vol.69
, pp. 2699-2706
-
-
Hwang, E.I.1
Kaneko, M.2
Ohnishi, Y.3
Horinouchi, S.4
-
31
-
-
0141755310
-
Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells
-
Ikezawa N., Tanaka M., Nagayoshi M., Shinkyo R., Sakaki T., Inouye K., and Sato F. Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells. J. Biol. Chem. 278 (2003) 38557-38565
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38557-38565
-
-
Ikezawa, N.1
Tanaka, M.2
Nagayoshi, M.3
Shinkyo, R.4
Sakaki, T.5
Inouye, K.6
Sato, F.7
-
32
-
-
0034789998
-
Taxol: biosynthesis, molecular genetics, and biotechnological applications
-
Jennewein S., and Croteau R. Taxol: biosynthesis, molecular genetics, and biotechnological applications. Appl. Microbiol. Biotechnol. 57 (2001) 13-19
-
(2001)
Appl. Microbiol. Biotechnol.
, vol.57
, pp. 13-19
-
-
Jennewein, S.1
Croteau, R.2
-
33
-
-
2642518854
-
Cytochrome p450 taxadiene 5α-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis
-
Jennewein S., Long R.M., Williams R.M., and Croteau R. Cytochrome p450 taxadiene 5α-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis. Chem. Biol. 11 (2004) 379-387
-
(2004)
Chem. Biol.
, vol.11
, pp. 379-387
-
-
Jennewein, S.1
Long, R.M.2
Williams, R.M.3
Croteau, R.4
-
34
-
-
15944383707
-
Coexpression in yeast of Taxus cytochrome P450 reductase with cytochrome P450 oxygenases involved in Taxol biosynthesis
-
Jennewein S., Park H., Dejong J.M., Long R.M., Bollon A.P., and Croteau R.B. Coexpression in yeast of Taxus cytochrome P450 reductase with cytochrome P450 oxygenases involved in Taxol biosynthesis. Biotechnol. Bioeng. 89 (2005) 588-598
-
(2005)
Biotechnol. Bioeng.
, vol.89
, pp. 588-598
-
-
Jennewein, S.1
Park, H.2
Dejong, J.M.3
Long, R.M.4
Bollon, A.P.5
Croteau, R.B.6
-
35
-
-
0242669969
-
Taxoid metabolism: taxoid 14β-hydroxylase is a cytochrome P450-dependent monooxygenase
-
Jennewein S., Rithner C.D., Williams R.M., and Croteau R. Taxoid metabolism: taxoid 14β-hydroxylase is a cytochrome P450-dependent monooxygenase. Arch. Biochem. Biophys. 413 (2003) 262-270
-
(2003)
Arch. Biochem. Biophys.
, vol.413
, pp. 262-270
-
-
Jennewein, S.1
Rithner, C.D.2
Williams, R.M.3
Croteau, R.4
-
37
-
-
2942656782
-
Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis
-
Jennewein S., Wildung M.R., Chau M., Walker K., and Croteau R. Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 9149-9154
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 9149-9154
-
-
Jennewein, S.1
Wildung, M.R.2
Chau, M.3
Walker, K.4
Croteau, R.5
-
38
-
-
0034496492
-
Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria
-
Jones K.L., Kim S.W., and Keasling J.D. Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. Metab. Eng. 2 (2000) 328-338
-
(2000)
Metab. Eng.
, vol.2
, pp. 328-338
-
-
Jones, K.L.1
Kim, S.W.2
Keasling, J.D.3
-
39
-
-
0141594681
-
Heterologous production of flavanones in Escherichia coli: potential for combinatorial biosynthesis of flavonoids in bacteria
-
Kaneko M., Hwang E.I., Ohnishi Y., and Horinouchi S. Heterologous production of flavanones in Escherichia coli: potential for combinatorial biosynthesis of flavonoids in bacteria. J. Ind. Microbiol. Biotechnol. 30 (2003) 456-461
-
(2003)
J. Ind. Microbiol. Biotechnol.
, vol.30
, pp. 456-461
-
-
Kaneko, M.1
Hwang, E.I.2
Ohnishi, Y.3
Horinouchi, S.4
-
40
-
-
0345701916
-
Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus × media cell cultures
-
Ketchum R.E., Rithner C.D., Qiu D., Kim Y.S., Williams R.M., and Croteau R.B. Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus × media cell cultures. Phytochemistry 62 (2003) 901-909
-
(2003)
Phytochemistry
, vol.62
, pp. 901-909
-
-
Ketchum, R.E.1
Rithner, C.D.2
Qiu, D.3
Kim, Y.S.4
Williams, R.M.5
Croteau, R.B.6
-
41
-
-
0035916370
-
Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway in Escherichia coli enhances lycopene production
-
Kim S., and Keasling J. Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway in Escherichia coli enhances lycopene production. Biotechnol. Bioeng. 72 (2001) 408-415
-
(2001)
Biotechnol. Bioeng.
, vol.72
, pp. 408-415
-
-
Kim, S.1
Keasling, J.2
-
43
-
-
0141705406
-
The bioconversion process of deoxypodophyllotoxin with Linum flavum cell cultures
-
Koulman A., Beekman A.C., Pras N., and Quax W.J. The bioconversion process of deoxypodophyllotoxin with Linum flavum cell cultures. Planta Med. 69 (2003) 739-744
-
(2003)
Planta Med.
, vol.69
, pp. 739-744
-
-
Koulman, A.1
Beekman, A.C.2
Pras, N.3
Quax, W.J.4
-
44
-
-
0028083884
-
Heterologous expression of the plant proteins strictosidine synthase and berberine bridge enzyme in insect cell culture
-
Kutchan T.M., Bock A., and Dittrich H. Heterologous expression of the plant proteins strictosidine synthase and berberine bridge enzyme in insect cell culture. Phytochemistry 35 (1994) 353-360
-
(1994)
Phytochemistry
, vol.35
, pp. 353-360
-
-
Kutchan, T.M.1
Bock, A.2
Dittrich, H.3
-
45
-
-
0024285106
-
The cDNA clone for strictosidine synthase from Rauvolfia serpentina. DNA sequence determination and expression in Escherichia coli
-
Kutchan T.M., Hampp N., Lottspeich F., Beyreuther K., and Zenk M.H. The cDNA clone for strictosidine synthase from Rauvolfia serpentina. DNA sequence determination and expression in Escherichia coli. FEBS Lett. 237 (1988) 40-44
-
(1988)
FEBS Lett.
, vol.237
, pp. 40-44
-
-
Kutchan, T.M.1
Hampp, N.2
Lottspeich, F.3
Beyreuther, K.4
Zenk, M.H.5
-
46
-
-
0034700150
-
Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes
-
Lange B.M., Rujan T., Martin W., and Croteau R. Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 13172-13177
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13172-13177
-
-
Lange, B.M.1
Rujan, T.2
Martin, W.3
Croteau, R.4
-
47
-
-
0028263720
-
Agricultural production of artemisinin-a review
-
Laughlin J.C. Agricultural production of artemisinin-a review. Trans. R. Soc. Trop. Med. Hyg. 88 Suppl. 1 (1994) S21-S22
-
(1994)
Trans. R. Soc. Trop. Med. Hyg.
, vol.88
, Issue.SUPPL. 1
-
-
Laughlin, J.C.1
-
48
-
-
0037209731
-
Metabolic engineering towards biotechnological production of carotenoids in microorganisms
-
Lee P.C., and Schmidt-Dannert C. Metabolic engineering towards biotechnological production of carotenoids in microorganisms. Appl. Microbiol. Biotechnol. 60 (2002) 1-11
-
(2002)
Appl. Microbiol. Biotechnol.
, vol.60
, pp. 1-11
-
-
Lee, P.C.1
Schmidt-Dannert, C.2
-
49
-
-
0029559296
-
Acetyl coenzyme A: salutaridinol-7-O-acetyltransferase from Papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis
-
Lenz R., and Zenk M.H. Acetyl coenzyme A: salutaridinol-7-O-acetyltransferase from Papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis. J. Biol. Chem. 270 (1995) 31091-31096
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 31091-31096
-
-
Lenz, R.1
Zenk, M.H.2
-
50
-
-
0028871826
-
Purification and properties of codeinone reductase (NADPH) from Papaver somniferum cell cultures and differentiated plants
-
Lenz R., and Zenk M.H. Purification and properties of codeinone reductase (NADPH) from Papaver somniferum cell cultures and differentiated plants. Eur. J. Biochem. 233 (1995) 132-139
-
(1995)
Eur. J. Biochem.
, vol.233
, pp. 132-139
-
-
Lenz, R.1
Zenk, M.H.2
-
51
-
-
0036375597
-
Structure, mechanism and function of prenyltransferases
-
Liang P.H., Ko T.P., and Wang A.H. Structure, mechanism and function of prenyltransferases. Eur. J. Biochem. 269 (2002) 3339-3354
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 3339-3354
-
-
Liang, P.H.1
Ko, T.P.2
Wang, A.H.3
-
52
-
-
33645851015
-
Production of the artemisinin precursor amorpha-4,11-diene by engineered Saccharomyces cerevisiae
-
Lindahl A.L., Olsson M.E., Mercke P., Tollbom O., Schelin J., Brodelius M., and Brodelius P.E. Production of the artemisinin precursor amorpha-4,11-diene by engineered Saccharomyces cerevisiae. Biotechnol. Lett. 28 (2006) 571-580
-
(2006)
Biotechnol. Lett.
, vol.28
, pp. 571-580
-
-
Lindahl, A.L.1
Olsson, M.E.2
Mercke, P.3
Tollbom, O.4
Schelin, J.5
Brodelius, M.6
Brodelius, P.E.7
-
53
-
-
0031891058
-
Production of artemisinin by hairy root cultures of Artemisia annua L. in bioreactor
-
Liu C.Z., Wang Y.C., Ouyang F., Ye H.C., and Li G.F. Production of artemisinin by hairy root cultures of Artemisia annua L. in bioreactor. Biotechnol. Lett. 20 (1998) 265-268
-
(1998)
Biotechnol. Lett.
, vol.20
, pp. 265-268
-
-
Liu, C.Z.1
Wang, Y.C.2
Ouyang, F.3
Ye, H.C.4
Li, G.F.5
-
54
-
-
27544457332
-
Preliminary assessment of the C13-side chain 2′-hydroxylase involved in taxol biosynthesis
-
Long R.M., and Croteau R. Preliminary assessment of the C13-side chain 2′-hydroxylase involved in taxol biosynthesis. Biochem. Biophys. Res. Commun. 338 (2005) 410-417
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 410-417
-
-
Long, R.M.1
Croteau, R.2
-
55
-
-
23744514106
-
Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants
-
Ma J.K., Barros E., Bock R., Christou P., Dale P.J., Dix P.J., Fischer R., Irwin J., Mahoney R., Pezzotti M., Schillberg S., Sparrow P., Stoger E., and Twyman R.M. Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants. EMBO Rep. 6 (2005) 593-599
-
(2005)
EMBO Rep.
, vol.6
, pp. 593-599
-
-
Ma, J.K.1
Barros, E.2
Bock, R.3
Christou, P.4
Dale, P.J.5
Dix, P.J.6
Fischer, R.7
Irwin, J.8
Mahoney, R.9
Pezzotti, M.10
Schillberg, S.11
Sparrow, P.12
Stoger, E.13
Twyman, R.M.14
-
56
-
-
0036200541
-
The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease
-
Mares-Perlman J.A., Millen A.E., Ficek T.L., and Hankinson S.E. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. J. Nutr. 132 (2002) 518S-524S
-
(2002)
J. Nutr.
, vol.132
-
-
Mares-Perlman, J.A.1
Millen, A.E.2
Ficek, T.L.3
Hankinson, S.E.4
-
57
-
-
0038391517
-
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
-
Martin V.J., Pitera D.J., Withers S.T., Newman J.D., and Keasling J.D. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat. Biotechnol. 21 (2003) 796-802
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 796-802
-
-
Martin, V.J.1
Pitera, D.J.2
Withers, S.T.3
Newman, J.D.4
Keasling, J.D.5
-
58
-
-
0035814339
-
The in vivo synthesis of plant sesquiterpenes by Escherichia coli
-
Martin V.J., Yoshikuni Y., and Keasling J.D. The in vivo synthesis of plant sesquiterpenes by Escherichia coli. Biotechnol. Bioeng. 75 (2001) 497-503
-
(2001)
Biotechnol. Bioeng.
, vol.75
, pp. 497-503
-
-
Martin, V.J.1
Yoshikuni, Y.2
Keasling, J.D.3
-
59
-
-
0026638165
-
The crtE gene in Erwinia herbicola encodes geranylgeranyl diphosphate synthase
-
Math S.K., Hearst J.E., and Poulter C.D. The crtE gene in Erwinia herbicola encodes geranylgeranyl diphosphate synthase. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 6761-6764
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 6761-6764
-
-
Math, S.K.1
Hearst, J.E.2
Poulter, C.D.3
-
61
-
-
0037478973
-
Mutants and intersexual heterokaryons of Blakeslea trispora for production of β-carotene and lycopene
-
Mehta B.J., Obraztsova I.N., and Cerda-Olmedo E. Mutants and intersexual heterokaryons of Blakeslea trispora for production of β-carotene and lycopene. Appl. Environ. Microbiol. 69 (2003) 4043-4048
-
(2003)
Appl. Environ. Microbiol.
, vol.69
, pp. 4043-4048
-
-
Mehta, B.J.1
Obraztsova, I.N.2
Cerda-Olmedo, E.3
-
62
-
-
0034664686
-
Molecular cloning, expression, and characterization of amorpha-4,11- diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L
-
Mercke P., Bengtsson M., Bouwmeester H.J., Posthumus M.A., and Brodelius P.E. Molecular cloning, expression, and characterization of amorpha-4,11- diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L. Arch. Biochem. Biophys. 381 (2000) 173-180
-
(2000)
Arch. Biochem. Biophys.
, vol.381
, pp. 173-180
-
-
Mercke, P.1
Bengtsson, M.2
Bouwmeester, H.J.3
Posthumus, M.A.4
Brodelius, P.E.5
-
63
-
-
17844400062
-
Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution
-
Mijts B.N., Lee P.C., and Schmidt-Dannert C. Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution. Chem. Biol. 12 (2005) 453-460
-
(2005)
Chem. Biol.
, vol.12
, pp. 453-460
-
-
Mijts, B.N.1
Lee, P.C.2
Schmidt-Dannert, C.3
-
64
-
-
0025630190
-
Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli
-
Misawa N., Nakagawa M., Kobayashi K., Yamano S., Izawa Y., Nakamura K., and Harashima K. Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli. J. Bacteriol. 172 (1990) 6704-6712
-
(1990)
J. Bacteriol.
, vol.172
, pp. 6704-6712
-
-
Misawa, N.1
Nakagawa, M.2
Kobayashi, K.3
Yamano, S.4
Izawa, Y.5
Nakamura, K.6
Harashima, K.7
-
65
-
-
0031980175
-
Production of the carotenoids lycopene, β-carotene, and astaxanthin in the food yeast Candida utilis
-
Miura Y., Kondo K., Saito T., Shimada H., Fraser P.D., and Misawa N. Production of the carotenoids lycopene, β-carotene, and astaxanthin in the food yeast Candida utilis. Appl. Environ. Microbiol. 64 (1998) 1226-1229
-
(1998)
Appl. Environ. Microbiol.
, vol.64
, pp. 1226-1229
-
-
Miura, Y.1
Kondo, K.2
Saito, T.3
Shimada, H.4
Fraser, P.D.5
Misawa, N.6
-
66
-
-
0032485906
-
Production of lycopene by the food yeast, Candida utilis that does not naturally synthesize carotenoid
-
Miura Y., Kondo K., Shimada H., Saito T., Nakamura K., and Misawa N. Production of lycopene by the food yeast, Candida utilis that does not naturally synthesize carotenoid. Biotechnol. Bioeng. 58 (1998) 306-308
-
(1998)
Biotechnol. Bioeng.
, vol.58
, pp. 306-308
-
-
Miura, Y.1
Kondo, K.2
Shimada, H.3
Saito, T.4
Nakamura, K.5
Misawa, N.6
-
67
-
-
33751244664
-
Combinatorial biosynthesis of flavones and flavonols in Escherichia coli
-
Miyahisa I., Funa N., Ohnishi Y., Martens S., Moriguchi T., and Horinouchi S. Combinatorial biosynthesis of flavones and flavonols in Escherichia coli. Appl. Microbiol. Biotechnol. (2005) 1-6
-
(2005)
Appl. Microbiol. Biotechnol.
, pp. 1-6
-
-
Miyahisa, I.1
Funa, N.2
Ohnishi, Y.3
Martens, S.4
Moriguchi, T.5
Horinouchi, S.6
-
68
-
-
27644520003
-
Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster
-
Miyahisa I., Kaneko M., Funa N., Kawasaki H., Kojima H., Ohnishi Y., and Horinouchi S. Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. Appl. Microbiol. Biotechnol. 68 (2005) 498-504
-
(2005)
Appl. Microbiol. Biotechnol.
, vol.68
, pp. 498-504
-
-
Miyahisa, I.1
Kaneko, M.2
Funa, N.3
Kawasaki, H.4
Kojima, H.5
Ohnishi, Y.6
Horinouchi, S.7
-
69
-
-
14744303071
-
Exploiting marine actinomycete biosynthetic pathways for drug discovery
-
Moore B.S., Kalaitzis J.A., and Xiang L. Exploiting marine actinomycete biosynthetic pathways for drug discovery. Antonie Van Leeuwenhoek 87 (2005) 49-57
-
(2005)
Antonie Van Leeuwenhoek
, vol.87
, pp. 49-57
-
-
Moore, B.S.1
Kalaitzis, J.A.2
Xiang, L.3
-
70
-
-
0028012837
-
Total synthesis of taxol
-
Nicolaou K.C., Yang Z., Liu J.J., Ueno H., Nantermet P.G., Guy R.K., Claiborne C.F., Renaud J., Couladouros E.A., and Paulvannan K. Total synthesis of taxol. Nature 367 (1994) 630-634
-
(1994)
Nature
, vol.367
, pp. 630-634
-
-
Nicolaou, K.C.1
Yang, Z.2
Liu, J.J.3
Ueno, H.4
Nantermet, P.G.5
Guy, R.K.6
Claiborne, C.F.7
Renaud, J.8
Couladouros, E.A.9
Paulvannan, K.10
-
71
-
-
0033746113
-
Commercial production of astaxanthin from Haematococcus pluvialis using 25,000-liter outdoor photobioreactors
-
Olaizola M. Commercial production of astaxanthin from Haematococcus pluvialis using 25,000-liter outdoor photobioreactors. J. Appl. Phycol. 12 (2000) 499-506
-
(2000)
J. Appl. Phycol.
, vol.12
, pp. 499-506
-
-
Olaizola, M.1
-
72
-
-
18444395871
-
Production of the potent antibacterial polyketide erythromycin C in Escherichia coli
-
Peiru S., Menzella H.G., Rodriguez E., Carney J., and Gramajo H. Production of the potent antibacterial polyketide erythromycin C in Escherichia coli. Appl. Environ. Microbiol. 71 (2005) 2539-2547
-
(2005)
Appl. Environ. Microbiol.
, vol.71
, pp. 2539-2547
-
-
Peiru, S.1
Menzella, H.G.2
Rodriguez, E.3
Carney, J.4
Gramajo, H.5
-
73
-
-
0035102454
-
Biosynthesis of polyketides in heterologous hosts
-
Pfeifer B.A., and Khosla C. Biosynthesis of polyketides in heterologous hosts. Microbiol. Mol. Biol. Rev. 65 (2001) 106-118
-
(2001)
Microbiol. Mol. Biol. Rev.
, vol.65
, pp. 106-118
-
-
Pfeifer, B.A.1
Khosla, C.2
-
74
-
-
17744370937
-
Expression, purification, and characterization of recombinant amorpha-4,11-diene synthase from Artemisia annua L
-
Picaud S., Olofsson L., Brodelius M., and Brodelius P.E. Expression, purification, and characterization of recombinant amorpha-4,11-diene synthase from Artemisia annua L. Arch. Biochem. Biophys. 436 (2005) 215-226
-
(2005)
Arch. Biochem. Biophys.
, vol.436
, pp. 215-226
-
-
Picaud, S.1
Olofsson, L.2
Brodelius, M.3
Brodelius, P.E.4
-
75
-
-
0033779923
-
Genetics and biochemistry of secondary metabolites in plants: an evolutionary perspective
-
Pichersky E., and Gang D.R. Genetics and biochemistry of secondary metabolites in plants: an evolutionary perspective. Trends Plant Sci. 5 (2000) 439-445
-
(2000)
Trends Plant Sci.
, vol.5
, pp. 439-445
-
-
Pichersky, E.1
Gang, D.R.2
-
76
-
-
0026660940
-
Bioconversion of naturally occurring precursors and related synthetic compounds using plant cell cultures
-
Pras N. Bioconversion of naturally occurring precursors and related synthetic compounds using plant cell cultures. J. Biotechnol. 26 (1992) 29-62
-
(1992)
J. Biotechnol.
, vol.26
, pp. 29-62
-
-
Pras, N.1
-
77
-
-
33645870422
-
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
-
Ro D.K., Paradise E.M., Ouellet M., Fisher K.J., Newman K.L., Ndungu J.M., Ho K.A., Eachus R.A., Ham T.S., Kirby J., Chang M.C., Withers S.T., Shiba Y., Sarpong R., and Keasling J.D. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 440 (2006) 940-943
-
(2006)
Nature
, vol.440
, pp. 940-943
-
-
Ro, D.K.1
Paradise, E.M.2
Ouellet, M.3
Fisher, K.J.4
Newman, K.L.5
Ndungu, J.M.6
Ho, K.A.7
Eachus, R.A.8
Ham, T.S.9
Kirby, J.10
Chang, M.C.11
Withers, S.T.12
Shiba, Y.13
Sarpong, R.14
Keasling, J.D.15
-
78
-
-
0031474314
-
Carotenoids: biology and treatment
-
Rock C.L. Carotenoids: biology and treatment. Pharmacol. Ther. 75 (1997) 185-197
-
(1997)
Pharmacol. Ther.
, vol.75
, pp. 185-197
-
-
Rock, C.L.1
-
79
-
-
0034788156
-
Combinatorial biosynthesis of antimicrobials and other natural products
-
Rodriguez E., and McDaniel R. Combinatorial biosynthesis of antimicrobials and other natural products. Curr. Opin. Microbiol. 4 (2001) 526-534
-
(2001)
Curr. Opin. Microbiol.
, vol.4
, pp. 526-534
-
-
Rodriguez, E.1
McDaniel, R.2
-
80
-
-
0035478823
-
The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates
-
Rohdich F., Kis K., Bacher A., and Eisenreich W. The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates. Curr. Opin. Chem. Biol. 5 (2001) 535-540
-
(2001)
Curr. Opin. Chem. Biol.
, vol.5
, pp. 535-540
-
-
Rohdich, F.1
Kis, K.2
Bacher, A.3
Eisenreich, W.4
-
81
-
-
0037072805
-
Purification and characterization of norcoclaurine synthase. The first committed enzyme in benzylisoquinoline alkaloid biosynthesis in plants
-
Samanani N., and Facchini P.J. Purification and characterization of norcoclaurine synthase. The first committed enzyme in benzylisoquinoline alkaloid biosynthesis in plants. J. Biol. Chem. 277 (2002) 33878-33883
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33878-33883
-
-
Samanani, N.1
Facchini, P.J.2
-
82
-
-
6444243887
-
Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis
-
Samanani N., Liscombe D.K., and Facchini P.J. Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis. Plant J. 40 (2004) 302-313
-
(2004)
Plant J.
, vol.40
, pp. 302-313
-
-
Samanani, N.1
Liscombe, D.K.2
Facchini, P.J.3
-
83
-
-
33745047747
-
Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives
-
Sanchez C., Mendez C., and Salas J.A. Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives. J. Ind. Microbiol. Biotechnol (2006)
-
(2006)
J. Ind. Microbiol. Biotechnol
-
-
Sanchez, C.1
Mendez, C.2
Salas, J.A.3
-
84
-
-
12244279574
-
Combinatorial biosynthesis of antitumor indolocarbazole compounds
-
Sanchez C., Zhu L., Brana A.F., Salas A.P., Rohr J., Mendez C., and Salas J.A. Combinatorial biosynthesis of antitumor indolocarbazole compounds. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 461-466
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 461-466
-
-
Sanchez, C.1
Zhu, L.2
Brana, A.F.3
Salas, A.P.4
Rohr, J.5
Mendez, C.6
Salas, J.A.7
-
85
-
-
0035207633
-
Genetic manipulation of carotenoid biosynthesis: strategies, problems and achievements
-
Sandmann G. Genetic manipulation of carotenoid biosynthesis: strategies, problems and achievements. Trends Plant Sci. 6 (2001) 14-17
-
(2001)
Trends Plant Sci.
, vol.6
, pp. 14-17
-
-
Sandmann, G.1
-
86
-
-
0036901989
-
Combinatorial biosynthesis of carotenoids in a heterologous host: a powerful approach for the biosynthesis of novel structures
-
Sandmann G. Combinatorial biosynthesis of carotenoids in a heterologous host: a powerful approach for the biosynthesis of novel structures. Chem. Biochem. 3 (2002) 629-635
-
(2002)
Chem. Biochem.
, vol.3
, pp. 629-635
-
-
Sandmann, G.1
-
87
-
-
0033941389
-
Molecular breeding of carotenoid biosynthetic pathways
-
Schmidt-Dannert C., Umeno D., and Arnold F.H. Molecular breeding of carotenoid biosynthetic pathways. Nat. Biotechnol. 18 (2000) 750-753
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 750-753
-
-
Schmidt-Dannert, C.1
Umeno, D.2
Arnold, F.H.3
-
88
-
-
0142036457
-
Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: tabersonine 16-hydroxylase
-
Schroder G., Unterbusch E., Kaltenbach M., Schmidt J., Strack D., De L.V., and Schroder J. Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: tabersonine 16-hydroxylase. FEBS Lett. 458 (1999) 97-102
-
(1999)
FEBS Lett.
, vol.458
, pp. 97-102
-
-
Schroder, G.1
Unterbusch, E.2
Kaltenbach, M.3
Schmidt, J.4
Strack, D.5
De, L.V.6
Schroder, J.7
-
89
-
-
33645281589
-
Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula
-
Shao H., He X., Achnine L., Blount J.W., Dixon R.A., and Wang X. Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula. Plant Cell 17 (2005) 3141-3154
-
(2005)
Plant Cell
, vol.17
, pp. 3141-3154
-
-
Shao, H.1
He, X.2
Achnine, L.3
Blount, J.W.4
Dixon, R.A.5
Wang, X.6
-
90
-
-
0031843028
-
Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway
-
Shimada H., Kondo K., Fraser P.D., Miura Y., Saito T., and Misawa N. Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway. Appl. Environ. Microbiol. 64 (1998) 2676-2680
-
(1998)
Appl. Environ. Microbiol.
, vol.64
, pp. 2676-2680
-
-
Shimada, H.1
Kondo, K.2
Fraser, P.D.3
Miura, Y.4
Saito, T.5
Misawa, N.6
-
91
-
-
9244251590
-
Anaerobic microbial dehalogenation
-
Smidt H., and de Vos W.M. Anaerobic microbial dehalogenation. Annu. Rev. Microbiol. 58 (2004) 43-73
-
(2004)
Annu. Rev. Microbiol.
, vol.58
, pp. 43-73
-
-
Smidt, H.1
de Vos, W.M.2
-
92
-
-
0032449901
-
Carotenoids and cancer: prevention and potential therapy
-
Smith T.A. Carotenoids and cancer: prevention and potential therapy. Br. J. Biomed. Sci. 55 (1998) 268-275
-
(1998)
Br. J. Biomed. Sci.
, vol.55
, pp. 268-275
-
-
Smith, T.A.1
-
93
-
-
0035212590
-
Controlling the metabolic flux through the carotenoid pathway using directed mRNA processing and stabilization
-
Smolke C.D., Martin V.J., and Keasling J.D. Controlling the metabolic flux through the carotenoid pathway using directed mRNA processing and stabilization. Metab. Eng. 3 (2001) 313-321
-
(2001)
Metab. Eng.
, vol.3
, pp. 313-321
-
-
Smolke, C.D.1
Martin, V.J.2
Keasling, J.D.3
-
94
-
-
0032104554
-
The terminal O-acetyltransferase involved in vindoline biosynthesis defines a new class of proteins responsible for coenzyme A-dependent acyl transfer
-
St Pierre B., Laflamme P., Alarco A.M., and De L.V. The terminal O-acetyltransferase involved in vindoline biosynthesis defines a new class of proteins responsible for coenzyme A-dependent acyl transfer. Plant J. 14 (1998) 703-713
-
(1998)
Plant J.
, vol.14
, pp. 703-713
-
-
St Pierre, B.1
Laflamme, P.2
Alarco, A.M.3
De, L.V.4
-
95
-
-
0029137429
-
Molecular cloning and characterization of S-adenosyl-l-methionine:scoulerine-9-O-methyltransferase from cultured cells of Coptis japonica
-
Takeshita N., Fujiwara H., Mimura H., Fitchen J.H., Yamada Y., and Sato F. Molecular cloning and characterization of S-adenosyl-l-methionine:scoulerine-9-O-methyltransferase from cultured cells of Coptis japonica. Plant Cell Physiol. 36 (1995) 29-36
-
(1995)
Plant Cell Physiol.
, vol.36
, pp. 29-36
-
-
Takeshita, N.1
Fujiwara, H.2
Mimura, H.3
Fitchen, J.H.4
Yamada, Y.5
Sato, F.6
-
96
-
-
32344437343
-
Artemisia annua L. Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin
-
Teoh K.H., Polichuk D.R., Reed D.W., Nowak G., and Covello P.S. Artemisia annua L. Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin. FEBS Lett. 580 (2006) 1411-1416
-
(2006)
FEBS Lett.
, vol.580
, pp. 1411-1416
-
-
Teoh, K.H.1
Polichuk, D.R.2
Reed, D.W.3
Nowak, G.4
Covello, P.S.5
-
97
-
-
33645975530
-
Biosynthesis of novel carotenoid families based on unnatural carbon backbones: a model for diversification of natural product pathways
-
Tobias A.V., and Arnold F.H. Biosynthesis of novel carotenoid families based on unnatural carbon backbones: a model for diversification of natural product pathways. Biochim. Biophys. Acta 1761 (2006) 235-246
-
(2006)
Biochim. Biophys. Acta
, vol.1761
, pp. 235-246
-
-
Tobias, A.V.1
Arnold, F.H.2
-
98
-
-
1342304132
-
Evolution of a pathway to novel long-chain carotenoids
-
Umeno D., and Arnold F.H. Evolution of a pathway to novel long-chain carotenoids. J. Bacteriol. 186 (2004) 1531-1536
-
(2004)
J. Bacteriol.
, vol.186
, pp. 1531-1536
-
-
Umeno, D.1
Arnold, F.H.2
-
99
-
-
1642263128
-
The Catharanthus alkaloids: pharmacognosy and biotechnology
-
Van der Heijden R., Jacobs D.I., Snoeijer W., Hallared D., and Verpoorte R. The Catharanthus alkaloids: pharmacognosy and biotechnology. Curr. Med. Chem. 11 (2004) 607-628
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 607-628
-
-
Van der Heijden, R.1
Jacobs, D.I.2
Snoeijer, W.3
Hallared, D.4
Verpoorte, R.5
-
100
-
-
0030933558
-
The large scale isolation of deoxypodophyllotoxin from rhizomes of Anthriscus sylvestris followed by its bioconversion into 5-methoxypodophyllotoxin b-d-glucoside by cell cultures of Linum flavum
-
Van Uden W., Bos J.A., Boeke G.M., Woerdenbag H.J., and Pras N. The large scale isolation of deoxypodophyllotoxin from rhizomes of Anthriscus sylvestris followed by its bioconversion into 5-methoxypodophyllotoxin b-d-glucoside by cell cultures of Linum flavum. J. Nat. Prod. 60 (1997) 401-403
-
(1997)
J. Nat. Prod.
, vol.60
, pp. 401-403
-
-
Van Uden, W.1
Bos, J.A.2
Boeke, G.M.3
Woerdenbag, H.J.4
Pras, N.5
-
101
-
-
0031214493
-
Molecular cloning and characterization of desacetoxyvindoline-4-hydroxylase. A 2-oxoglutarate dependent dioxygenase involved in the biosynthesis of vindoline in Catharanthus roseus (L.) G Don
-
Vazquez-Flota F., De Carolis E., Alarco A.M., and De Luca V. Molecular cloning and characterization of desacetoxyvindoline-4-hydroxylase. A 2-oxoglutarate dependent dioxygenase involved in the biosynthesis of vindoline in Catharanthus roseus (L.) G Don. Plant Mol. Biol. 34 (1997) 935-948
-
(1997)
Plant Mol. Biol.
, vol.34
, pp. 935-948
-
-
Vazquez-Flota, F.1
De Carolis, E.2
Alarco, A.M.3
De Luca, V.4
-
102
-
-
0037479864
-
Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma)
-
Verdoes J.C., Sandmann G., Visser H., Diaz M., van Mossel M., and van Ooyen A.J. Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma). Appl. Environ. Microbiol. 69 (2003) 3728-3738
-
(2003)
Appl. Environ. Microbiol.
, vol.69
, pp. 3728-3738
-
-
Verdoes, J.C.1
Sandmann, G.2
Visser, H.3
Diaz, M.4
van Mossel, M.5
van Ooyen, A.J.6
-
103
-
-
23044511375
-
Ethnopharmacology and systems biology: a perfect holistic match
-
Verpoorte R., Choi Y.H., and Kim H.K. Ethnopharmacology and systems biology: a perfect holistic match. J. Ethnopharmacol. 100 (2005) 53-56
-
(2005)
J. Ethnopharmacol.
, vol.100
, pp. 53-56
-
-
Verpoorte, R.1
Choi, Y.H.2
Kim, H.K.3
-
104
-
-
0027453163
-
Plant-cell biotechnology for the production of alkaloids-present status and prospects
-
Verpoorte R., Van der Heijden R., Schripsema J., Hoge J.H.C., and ten Hoopen H.J.G. Plant-cell biotechnology for the production of alkaloids-present status and prospects. J. Nat. Prod. 56 (1993) 186-207
-
(1993)
J. Nat. Prod.
, vol.56
, pp. 186-207
-
-
Verpoorte, R.1
Van der Heijden, R.2
Schripsema, J.3
Hoge, J.H.C.4
ten Hoopen, H.J.G.5
-
105
-
-
0345118986
-
Metabolic engineering of the astaxanthin-biosynthetic pathway of Xanthophyllomyces dendrorhous
-
Visser H., van Ooyen A.J., and Verdoes J.C. Metabolic engineering of the astaxanthin-biosynthetic pathway of Xanthophyllomyces dendrorhous. FEMS Yeast Res. 4 (2003) 221-231
-
(2003)
FEMS Yeast Res.
, vol.4
, pp. 221-231
-
-
Visser, H.1
van Ooyen, A.J.2
Verdoes, J.C.3
-
107
-
-
0034681193
-
Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli
-
Walker K., and Croteau R. Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 583-587
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 583-587
-
-
Walker, K.1
Croteau, R.2
-
108
-
-
0034610386
-
Taxol biosynthesis: molecular cloning of a benzoyl-CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli
-
Walker K., and Croteau R. Taxol biosynthesis: molecular cloning of a benzoyl-CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 13591-13596
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13591-13596
-
-
Walker, K.1
Croteau, R.2
-
110
-
-
0036789932
-
Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis
-
Walker K., Fujisaki S., Long R., and Croteau R. Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 12715-12720
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 12715-12720
-
-
Walker, K.1
Fujisaki, S.2
Long, R.3
Croteau, R.4
-
111
-
-
0037047151
-
The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus
-
Walker K., Long R., and Croteau R. The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 9166-9171
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 9166-9171
-
-
Walker, K.1
Long, R.2
Croteau, R.3
-
112
-
-
0034652139
-
Molecular cloning of a taxa-4(20),11(12)-dien-5α-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli
-
Walker K., Schoendorf A., and Croteau R. Molecular cloning of a taxa-4(20),11(12)-dien-5α-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli. Arch. Biochem. Biophys. 374 (2000) 371-380
-
(2000)
Arch. Biochem. Biophys.
, vol.374
, pp. 371-380
-
-
Walker, K.1
Schoendorf, A.2
Croteau, R.3
-
113
-
-
11144225850
-
Cloning, heterologous expression, and characterization of a phenylalanine aminomutase involved in Taxol biosynthesis
-
Walker K.D., Klettke K., Akiyama T., and Croteau R. Cloning, heterologous expression, and characterization of a phenylalanine aminomutase involved in Taxol biosynthesis. J. Biol. Chem. 279 (2004) 53947-53954
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 53947-53954
-
-
Walker, K.D.1
Klettke, K.2
Akiyama, T.3
Croteau, R.4
-
114
-
-
0035129779
-
Amorpha-4,11-diene synthase: cloning and functional expression of a key enzyme in the biosynthetic pathway of the novel antimalarial drug artemisinin
-
Wallaart T.E., Bouwmeester H.J., Hille J., Poppinga L., and Maijers N.C. Amorpha-4,11-diene synthase: cloning and functional expression of a key enzyme in the biosynthetic pathway of the novel antimalarial drug artemisinin. Planta 212 (2001) 460-465
-
(2001)
Planta
, vol.212
, pp. 460-465
-
-
Wallaart, T.E.1
Bouwmeester, H.J.2
Hille, J.3
Poppinga, L.4
Maijers, N.C.5
-
115
-
-
0033983929
-
Seasonal variation of artemisinin and its biosynthetic precursors in plants of Artemisia annua of different geographical origin: proof for the existence of chemotypes
-
Wallaart T.E., Pras N., Beekman A.C., and Quax W.J. Seasonal variation of artemisinin and its biosynthetic precursors in plants of Artemisia annua of different geographical origin: proof for the existence of chemotypes. Planta Med. 66 (2000) 57-62
-
(2000)
Planta Med.
, vol.66
, pp. 57-62
-
-
Wallaart, T.E.1
Pras, N.2
Beekman, A.C.3
Quax, W.J.4
-
116
-
-
0033585443
-
Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli
-
Wang C.W., Oh M.K., and Liao J.C. Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli. Biotechnol. Bioeng. 62 (1999) 235-241
-
(1999)
Biotechnol. Bioeng.
, vol.62
, pp. 235-241
-
-
Wang, C.W.1
Oh, M.K.2
Liao, J.C.3
-
117
-
-
0015211527
-
Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
-
Wani M.C., Taylor H.L., Wall M.E., Coggon P., and McPhail A.T. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Chem. Soc. 93 (1971) 2325-2327
-
(1971)
J. Am. Chem. Soc.
, vol.93
, pp. 2325-2327
-
-
Wani, M.C.1
Taylor, H.L.2
Wall, M.E.3
Coggon, P.4
McPhail, A.T.5
-
118
-
-
0034705965
-
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis
-
Warzecha H., Gerasimenko I., Kutchan T.M., and Stockigt J. Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis. Phytochemistry 54 (2000) 657-666
-
(2000)
Phytochemistry
, vol.54
, pp. 657-666
-
-
Warzecha, H.1
Gerasimenko, I.2
Kutchan, T.M.3
Stockigt, J.4
-
119
-
-
0345550239
-
Exploiting the genetic potential of polyketide producing streptomycetes
-
Weber T., Welzel K., Pelzer S., Vente A., and Wohlleben W. Exploiting the genetic potential of polyketide producing streptomycetes. J. Biotechnol. 106 (2003) 221-232
-
(2003)
J. Biotechnol.
, vol.106
, pp. 221-232
-
-
Weber, T.1
Welzel, K.2
Pelzer, S.3
Vente, A.4
Wohlleben, W.5
-
120
-
-
33751253909
-
-
Whitmer S., 1999. Aspects of terpenoid indole alkaloid formation by transgenic cell lines of Catharanthus roseus overexpressing tryptophan decarboxylase and strictosidine synthase. Thesis. LACDR, Leiden University, Leiden, The Netherlands.
-
-
-
-
121
-
-
0029873176
-
A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis
-
Wildung M.R., and Croteau R. A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis. J. Biol. Chem. 271 (1996) 9201-9204
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9201-9204
-
-
Wildung, M.R.1
Croteau, R.2
-
122
-
-
0034979805
-
Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology
-
Winkel-Shirley B. Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. Plant Physiol. 126 (2001) 485-493
-
(2001)
Plant Physiol.
, vol.126
, pp. 485-493
-
-
Winkel-Shirley, B.1
-
124
-
-
0033983338
-
Engineering the provitamin A (β-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
-
Ye X., Al Babili S., Kloti A., Zhang J., Lucca P., Beyer P., and Potrykus I. Engineering the provitamin A (β-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science 287 (2000) 303-305
-
(2000)
Science
, vol.287
, pp. 303-305
-
-
Ye, X.1
Al Babili, S.2
Kloti, A.3
Zhang, J.4
Lucca, P.5
Beyer, P.6
Potrykus, I.7
-
125
-
-
29544444196
-
Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli
-
Yuan L.Z., Rouviere P.E., Larossa R.A., and Suh W. Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli. Metab. Eng. 8 (2006) 79-90
-
(2006)
Metab. Eng.
, vol.8
, pp. 79-90
-
-
Yuan, L.Z.1
Rouviere, P.E.2
Larossa, R.A.3
Suh, W.4
-
126
-
-
0035054985
-
Terpenoid indole alkaloid profile changes in Catharanthus pusillus during development
-
Zarate R., Dirks C., van der H.R., and Verpoorte R. Terpenoid indole alkaloid profile changes in Catharanthus pusillus during development. Plant Sci. 160 (2001) 971-977
-
(2001)
Plant Sci.
, vol.160
, pp. 971-977
-
-
Zarate, R.1
Dirks, C.2
van der, H.R.3
Verpoorte, R.4
-
127
-
-
19744367711
-
14-Hydroxylation of opiates: catalytic direct autoxidation of codeinone to 14-hydroxycodeinone
-
Zhang Q., Rich J.O., Cotterill I.C., Pantaleone D.P., and Michels P.C. 14-Hydroxylation of opiates: catalytic direct autoxidation of codeinone to 14-hydroxycodeinone. J. Am. Chem. Soc. 127 (2005) 7286-7287
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 7286-7287
-
-
Zhang, Q.1
Rich, J.O.2
Cotterill, I.C.3
Pantaleone, D.P.4
Michels, P.C.5
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