Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua

Planta Medica

Volumn 71, Issue 1, 2005, Pages 40-47

  Bertea, C M ^a,b   Freije, J R ^a   Van Der Woude, H ^a   Verstappen, F W A ^a   Perk, L ^a   Marquez, V ^a   De Kraker, J W ^a,c   Posthumus, M A ^a   Jansen, B J M ^a   De Groot, Ae ^a   Franssen, M C R ^a   Bouwmeester, H J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF TURIN   (Italy)

^c MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

Author keywords

Artemisia annua; Artemisinin; Asteraceae; Biosynthetic pathway; Glandular trichomes; Sesquiterpenoids

Indexed keywords

ALCOHOL DERIVATIVE; AMORPHA 4,11 DIENE; AMORPHA 4,11 DIENE HYDROXYLASE; ARTEMISIA ANNUA EXTRACT; ARTEMISINIC ACID; ARTEMISINIC ALCOHOL; ARTEMISINIC ALDEHYDE; ARTEMISININ; DIHYDROARTEMISINIC ACID; DIHYDROARTEMISINIC ALCOHOL; DIHYDROARTEMISINIC ALCOHOL DEHYDROGENASE; DIHYDROARTEMISINIC ALDEHYDE; DIHYDROARTEMISINIC ALDEHYDE DEHYDROGENASE; ENZYME; SQUALENE SYNTHASE; UNCLASSIFIED DRUG;

ARTEMISIA; ARTEMISIA ANNUA; ARTICLE; BIOSYNTHESIS; CHEMICAL BOND; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MECHANISM; HYDROXYLATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION REACTION; PLANT LEAF; SECRETORY CELL; TRICHOME;

ANTIMALARIALS; ARTEMISIA ANNUA; ARTEMISININS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; PHYTOTHERAPY; PLANT LEAVES;

EID: 13544263331     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-837749     Document Type: Article

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