Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives

Journal of Industrial Microbiology and Biotechnology

Volumn 33, Issue 7, 2006, Pages 560-568

  Sánchez, César ^a   Méndez, Carmen ^a   Salas, José A ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Glycosylation; Metabolic engineering; Rebeccamycin; Staurosporine; Streptomyces

Indexed keywords

12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE; 6 N METHYLARCYRIAFLAVIN C; ANTINEOPLASTIC AGENT; ARCYRIAFLAVIN A; ARCYRIARUBIN B; ATCC 39243; CARBAZOLE DERIVATIVE; CHROMOPYRROLIC ACID; DNA TOPOISOMERASE; DSM 10189; HOLYRINE A; N GLYCOSYLTRANSFERASE; NATURAL PRODUCT; PROTEIN KINASE INHIBITOR; REBECCAMYCIN; STAUROSPORINE; TJIPANAZOLE F 2; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANTINEOPLASTIC ACTIVITY; BACTERIAL STRAIN; CANCER; COMBINATORIAL CHEMISTRY; CONFERENCE PAPER; DEGENERATIVE DISEASE; DIMERIZATION; DRUG MANUFACTURE; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC ENGINEERING; HALOGENATION; NONHUMAN;

ANTIBIOTICS, ANTINEOPLASTIC; CARBAZOLES; GENES, BACTERIAL; GENETIC ENGINEERING; INDOLES; STAUROSPORINE;

ACTINOBACTERIA (CLASS);

EID: 33745047747     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-006-0092-5     Document Type: Conference Paper

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