Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 20, 2002, Pages 12715-12720

  Walker, Kevin ^a   Fujisaki, Shingo ^a,b   Long, Robert ^a   Croteau, Rodney ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b TOHO UNIVERSITY   (Japan)

Author keywords

Amino acid CoA esters; Baccatin III; C 13 O acyltransferase; Paclitaxel; Side chain attachment

Indexed keywords

ACYLTRANSFERASE; BACCATIN III; BENZENE DERIVATIVE; COMPLEMENTARY DNA; JASMONIC ACID; MESSENGER RNA; PACLITAXEL; PACLITAXEL DERIVATIVE;

ACYLATION; ARTICLE; BENZOYLATION; CALCULATION; CATALYSIS; CHEMICAL REACTION; DNA LIBRARY; DRUG ACTIVITY; DRUG SOLUBILITY; DRUG SYNTHESIS; MOLECULAR CLONING; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA ISOLATION; SPECTROMETRY; TAXUS;

ACYL COENZYME A; CARBOXYLIC ESTER HYDROLASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; DNA, COMPLEMENTARY; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PACLITAXEL; SUBSTRATE SPECIFICITY; TAXUS; TIME FACTORS;

TAXUS; TAXUS CUSPIDATA;

EID: 0036789932     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.192463699     Document Type: Article

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