메뉴 건너뛰기




Volumn 18, Issue 5, 2000, Pages 533-537

Improving lycopene production in Escherichia coli by engineering metabolic control

Author keywords

Carotenoids; Isoprenoids; Metabolic control; Metabolic engineering; Nitrogen regulon

Indexed keywords

LYCOPENE;

EID: 0034024497     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/75398     Document Type: Article
Times cited : (468)

References (35)
  • 1
    • 0025895183 scopus 로고
    • Toward a science of metabolic engineering
    • Bailey, J.E. Toward a science of metabolic engineering. Science 252, 1668-1675 (1991).
    • (1991) Science , vol.252 , pp. 1668-1675
    • Bailey, J.E.1
  • 2
    • 0033014686 scopus 로고    scopus 로고
    • Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production
    • Guillouet, S., Rodal, A.A., An, G., Lessard, P.A. & Sinskey, A.J. Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl. Environ. Microbiol. 65, 3100-3107 (1999).
    • (1999) Appl. Environ. Microbiol. , vol.65 , pp. 3100-3107
    • Guillouet, S.1    Rodal, A.A.2    An, G.3    Lessard, P.A.4    Sinskey, A.J.5
  • 3
    • 0030016417 scopus 로고    scopus 로고
    • Bacterial growth inhibition by overproduction of protein
    • Kurland, C.G. & Dong, H. Bacterial growth inhibition by overproduction of protein. Mol. Microbiol. 21, 1-4 (1996).
    • (1996) Mol. Microbiol. , vol.21 , pp. 1-4
    • Kurland, C.G.1    Dong, H.2
  • 4
    • 0031750314 scopus 로고    scopus 로고
    • Lycopene: Antioxidant and biological effects and its bioavailability in the human
    • Sies, H. & Stahl, W. Lycopene: antioxidant and biological effects and its bioavailability in the human. Proc. Soc. Exp. Biol. Med. 218, 121-124 (1998).
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.218 , pp. 121-124
    • Sies, H.1    Stahl, W.2
  • 5
    • 0033577044 scopus 로고    scopus 로고
    • Tomatoes, tomato-based products, lycopene and cancer: Review of the epidemiological literature
    • Giovannucci, E. Tomatoes, tomato-based products, lycopene and cancer: review of the epidemiological literature. J. Natl. Cancer Inst. 91, 317-331 (1999).
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 317-331
    • Giovannucci, E.1
  • 6
    • 0033585443 scopus 로고    scopus 로고
    • Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli
    • Wang, C.-W., Oh, M.-K. & Liao, J.C. Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli. Biotechnol. Bioeng. 62, 235-241 (1999).
    • (1999) Biotechnol. Bioeng. , vol.62 , pp. 235-241
    • Wang, C.-W.1    Oh, M.-K.2    Liao, J.C.3
  • 7
    • 0031980175 scopus 로고    scopus 로고
    • Production of the carotenoids lycopene, ß-carotene, and astaxanthin in the food yeast Candida utilis
    • Miura, Y. et al. Production of the carotenoids lycopene, ß-carotene, and astaxanthin in the food yeast Candida utilis. Appl. Environ. Microbiol. 64, 1226-1229 (1996).
    • (1996) Appl. Environ. Microbiol. , vol.64 , pp. 1226-1229
    • Miura, Y.1
  • 8
    • 0030970352 scopus 로고    scopus 로고
    • Expression of an exogenous isopentenyl diphosphate isomerase gene enhances isoprenoid biosynthesis in Escherichia coli
    • Kajiwara, S., Fraser, P.D., Kondo, K. & Misawa, N. Expression of an exogenous isopentenyl diphosphate isomerase gene enhances isoprenoid biosynthesis in Escherichia coli. Biochem. J. 324, 421-426 (1997).
    • (1997) Biochem. J. , vol.324 , pp. 421-426
    • Kajiwara, S.1    Fraser, P.D.2    Kondo, K.3    Misawa, N.4
  • 9
    • 0030772480 scopus 로고    scopus 로고
    • Production of zeaxanthin in Escherichia coli transformed with different carotenogenic plasmids
    • Ruther, A., Misawa, N. & Sandmann, G. Production of zeaxanthin in Escherichia coli transformed with different carotenogenic plasmids. Appl. Microbiol. Biotechnol. 48, 162-167 (1997).
    • (1997) Appl. Microbiol. Biotechnol. , vol.48 , pp. 162-167
    • Ruther, A.1    Misawa, N.2    Sandmann, G.3
  • 11
    • 0028335964 scopus 로고
    • The glucose-starvation stimulon of Escherichia coli: Induced and repressed synthesis of enzymes of central metabolic pathways and role of acetyl phosphate in gene expression and starvation survival
    • Nyström, T. The glucose-starvation stimulon of Escherichia coli: induced and repressed synthesis of enzymes of central metabolic pathways and role of acetyl phosphate in gene expression and starvation survival. Mol. Microbiol. 12, 833-843 (1994).
    • (1994) Mol. Microbiol. , vol.12 , pp. 833-843
    • Nyström, T.1
  • 12
    • 0028075844 scopus 로고
    • Acetyl phosphate and the activation of two-component response regulators
    • McCleary, W.R. & Stock, J.B. Acetyl phosphate and the activation of two-component response regulators. J. Biol. Chem. 269, 31567-31572 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 31567-31572
    • McCleary, W.R.1    Stock, J.B.2
  • 14
    • 0029844678 scopus 로고    scopus 로고
    • Involvement of the sensor kinase EnvZ in the in vivo activation of the response regulator PhoB by acetyl phosphate
    • Kim, S.-K., Wilmes-Riesenberg, M.R. & Wanner, B.L. Involvement of the sensor kinase EnvZ in the in vivo activation of the response regulator PhoB by acetyl phosphate. Mol. Microbiol. 22, 135-147 (1996).
    • (1996) Mol. Microbiol. , vol.22 , pp. 135-147
    • Kim, S.-K.1    Wilmes-Riesenberg, M.R.2    Wanner, B.L.3
  • 15
    • 0026662751 scopus 로고
    • Role of phosphorylated metabolic intermediates in the regulation of glutamine synthetase synthesis in Escherichia coli
    • Feng, J. et al. Role of phosphorylated metabolic intermediates in the regulation of glutamine synthetase synthesis in Escherichia coli. J. Bacteriol. 174, 6061-6070 (1992).
    • (1992) J. Bacteriol. , vol.174 , pp. 6061-6070
    • Feng, J.1
  • 16
    • 0021864787 scopus 로고
    • Expression of glnA in Escherichia coli is regulated at tandem promoters
    • Reitzer, L.J. & Magasanik, B. Expression of glnA in Escherichia coli is regulated at tandem promoters. Proc. Natl. Acad. Sci. USA 82, 1979-1983 (1985).
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 1979-1983
    • Reitzer, L.J.1    Magasanik, B.2
  • 17
    • 0028891890 scopus 로고
    • Activation of the dephosphorylation of nitrogen regulator I-phosphate of Escherichia coli
    • Liu, J. & Magasanik, B. Activation of the dephosphorylation of nitrogen regulator I-phosphate of Escherichia coli. J. Bacteriol. 177, 926-931 (1995).
    • (1995) J. Bacteriol. , vol.177 , pp. 926-931
    • Liu, J.1    Magasanik, B.2
  • 18
    • 0033609111 scopus 로고    scopus 로고
    • Physical evidence for a phosphorylation-dependent conformational change in the enhancer-binding protein NtrC
    • Hwang, I., Thorgeirsson, T., Lee, J., Kustu, S. & Shin, Y.K. Physical evidence for a phosphorylation-dependent conformational change in the enhancer-binding protein NtrC. Proc. Natl. Acad. Sci. USA 96, 4880-4885 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4880-4885
    • Hwang, I.1    Thorgeirsson, T.2    Lee, J.3    Kustu, S.4    Shin, Y.K.5
  • 19
    • 0026460088 scopus 로고
    • Stimulation of glucose catabolism in Escherichia coli by a potential futile cycle
    • Patnaik, R., Roof, W.D., Young, R.F. & Liao, J.C. Stimulation of glucose catabolism in Escherichia coli by a potential futile cycle. J. Bacteriol. 174, 7527-7532 (1992).
    • (1992) J. Bacteriol. , vol.174 , pp. 7527-7532
    • Patnaik, R.1    Roof, W.D.2    Young, R.F.3    Liao, J.C.4
  • 20
    • 0030696041 scopus 로고    scopus 로고
    • Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol
    • Sprenger, G.A. et al. Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol. Proc. Natl. Acad Sci. USA 94, 12857-12862 (1997).
    • (1997) Proc. Natl. Acad Sci. USA , vol.94 , pp. 12857-12862
    • Sprenger, G.A.1
  • 21
    • 0025630190 scopus 로고
    • Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli
    • Misawa, N. et al. Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli. J. Bacteriol. 172, 6704-6712 (1990).
    • (1990) J. Bacteriol. , vol.172 , pp. 6704-6712
    • Misawa, N.1
  • 22
    • 0025088052 scopus 로고
    • Low copy number plasmids for regulated low-level expression of cloned genes in Escherichia coli with blue/white insert screening capability
    • Lerner, C.G. & Inouye, M. Low copy number plasmids for regulated low-level expression of cloned genes in Escherichia coli with blue/white insert screening capability. Nucleic Acids Res. 18, 4631 (1990).
    • (1990) Nucleic Acids Res. , vol.18 , pp. 4631
    • Lerner, C.G.1    Inouye, M.2
  • 23
    • 0022870839 scopus 로고
    • Molecular cloning of the plasmid RP4 primase region in a multi-host range tacP expression vector
    • Fürste, J.P. et al. Molecular cloning of the plasmid RP4 primase region in a multi-host range tacP expression vector. Gene 48, 119-131 (1986).
    • (1986) Gene , vol.48 , pp. 119-131
    • Fürste, J.P.1
  • 24
    • 0029294180 scopus 로고
    • Pathway engineering for production of aromatics in Escherichia coli: Confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities
    • Patnaik, R., Spitzer, R.G. & Liao, J.C. Pathway engineering for production of aromatics in Escherichia coli: confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities. Biotechnol. Bioeng. 46, 361-370 (1995).
    • (1995) Biotechnol. Bioeng. , vol.46 , pp. 361-370
    • Patnaik, R.1    Spitzer, R.G.2    Liao, J.C.3
  • 25
    • 0028036558 scopus 로고
    • Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield
    • Patnaik, R. & Liao, J.C. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield. Appl. Environ. Microbiol. 60, 3903-3908 (1994).
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 3903-3908
    • Patnaik, R.1    Liao, J.C.2
  • 26
    • 0342762044 scopus 로고    scopus 로고
    • Improvement in recombinant protein production in ppGpp-deficient Escherichia coli
    • Dedhia, N., Richins, R, Mesina, A. & Chen, W. Improvement in recombinant protein production in ppGpp-deficient Escherichia coli. Biotechnol. Bioeng. 53, 379-(1997).
    • (1997) Biotechnol. Bioeng. , vol.53 , pp. 379
    • Dedhia, N.1    Richins, R.2    Mesina, A.3    Chen, W.4
  • 27
    • 0030853330 scopus 로고    scopus 로고
    • Reduction of aerobic acetate production by Escherichia coli
    • Farmer, W.R. & Liao, J.C. Reduction of aerobic acetate production by Escherichia coli. Appl. Environ. Microbiol. 63, 3205-3210 (1997).
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 3205-3210
    • Farmer, W.R.1    Liao, J.C.2
  • 28
    • 0028141650 scopus 로고
    • Threonine dehydratases of Corynebacterium glutamicum with altered allosteric control: Their generation and biochemical and structural analysis
    • Möckel, B., Eggeling, L. & Sahm, H. Threonine dehydratases of Corynebacterium glutamicum with altered allosteric control: their generation and biochemical and structural analysis. Mol. Microbiol. 13, 833-842 (1993).
    • (1993) Mol. Microbiol. , vol.13 , pp. 833-842
    • Möckel, B.1    Eggeling, L.2    Sahm, H.3
  • 29
    • 0031945008 scopus 로고    scopus 로고
    • Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells
    • Fussenegger, M., Schlatter, S., Bailey, J.E. & Mazur, X. Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells. Nat. Biotechnol. 16, 468-472 (1998).
    • (1998) Nat. Biotechnol. , vol.16 , pp. 468-472
    • Fussenegger, M.1    Schlatter, S.2    Bailey, J.E.3    Mazur, X.4
  • 30
    • 0023991777 scopus 로고
    • Identification and expression of genes narL and narX of the nar (nitrate reductase) locus in Escherichia coli K-12
    • Stewart, V. & Parales, J., Jr. Identification and expression of genes narL and narX of the nar (nitrate reductase) locus in Escherichia coli K-12. J. Bacteriol. 170, 1589-1597 (1988).
    • (1988) J. Bacteriol. , vol.170 , pp. 1589-1597
    • Stewart, V.1    Parales, J.2
  • 32
    • 0023255472 scopus 로고
    • Improved single and multicopy lacbased cloning vectors for protein and operon fusions
    • Simons, R.W., Houman, F. & Kleckner, N. Improved single and multicopy lacbased cloning vectors for protein and operon fusions. Gene 53, 85-96 (1987).
    • (1987) Gene , vol.53 , pp. 85-96
    • Simons, R.W.1    Houman, F.2    Kleckner, N.3
  • 33
    • 0000501863 scopus 로고
    • Biocatalytic syntesis of aromatics from D-glucose: The role of transketolase
    • Draths, K.M. et al. Biocatalytic syntesis of aromatics from D-glucose: the role of transketolase. J. Am. Chem. Soc. 114, 3956-3962 (1992).
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 3956-3962
    • Draths, K.M.1
  • 34
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.